METHANE SULFONIC ACID (MSA)

Methane Sulfonic Acid (MSA) is a strong, non-oxidizing organic acid widely used in chemical synthesis, electroplating, and industrial formulations.
Methane Sulfonic Acid (MSA) is recognized for its excellent solubility, high acidity, and biodegradability compared to mineral acids.
Methane Sulfonic Acid (MSA) is a clear, colorless liquid with low volatility and low corrosiveness to equipment, making it a safer and more environmentally friendly alternative to traditional acids.
MSA is commonly employed in pharmaceuticals, polymerization, metal surface treatment, and catalysis.

CAS Number: 75-75-2
EC Number: 200-898-6
Molecular Formula: CH4O3S
Molecular Weight: 96.10 g/mol

Synonyms: Methane Sulfonic Acid, MSA, Methanesulphonic Acid, Mesylic Acid, Methylsulfonic Acid, Sulfoacetic Acid (obsolete), CH3SO3H, Methane Sulfonate (conjugate base), Organic Sulfonic Acid MSA, Methane Sulfonic Catalyst, MSA Acid Grade, MSA Electroplating Additive, Methane Sulfonic Acid (MSA), Methanesulfonic Acid, Mesylic Acid, Methylsulfonic Acid, MSA Acid, MeSO₃H, CH₃SO₃H, Methanesulfonate Acid, Methane Sulfonate Acid, Methane Sulphonic Acid, Methanesulphonic Acid, Methane Sulfonic Acid Solution, Methane Sulfonic Acid Liquid, Methane Sulfonic Acid Concentrate, Methane Sulfonic Acid Compound, Methane Sulfonic Acid Material, Methane Sulfonic Acid Product, Methane Sulfonic Acid Reagent, Methane Sulfonic Acid Certified Reagent, Methane Sulfonic Acid Laboratory Reagent, Methane Sulfonic Acid Analytical Reagent, Methane Sulfonic Acid Certified Standard, Methane Sulfonic Acid Analytical Standard, Methane Sulfonic Acid Laboratory Standard, Methane Sulfonic Acid Assay, Methane Sulfonic Acid Pure, Methane Sulfonic Acid Extra Pure, Methane Sulfonic Acid High Purity, Methane Sulfonic Acid Refined, Methane Sulfonic Acid Stabilized, Methane Sulfonic Acid Certified, Methane Sulfonic Acid ACS Grade, Methane Sulfonic Acid AR Grade, Methane Sulfonic Acid CP Grade, Methane Sulfonic Acid USP Grade, Methane Sulfonic Acid BP Grade, Methane Sulfonic Acid EP Grade, Methane Sulfonic Acid Technical Grade, Methane Sulfonic Acid Industrial Grade, Methane Sulfonic Acid Pharmaceutical Grade, Methane Sulfonic Acid Food Grade, Methane Sulfonic Acid Cosmetic Grade, Methane Sulfonic Acid Research Grade, Methane Sulfonic Acid Laboratory Grade, Methane Sulfonic Acid Bulk Chemical, Methane Sulfonic Acid Commercial Grade, Methane Sulfonic Acid Raw Material

APPLICATIONS

Methane Sulfonic Acid (MSA) is used as an acid catalyst in organic synthesis.
Methane Sulfonic Acid (MSA) accelerates esterification and transesterification reactions.
Methane Sulfonic Acid (MSA) is applied in alkylation and condensation reactions.

Methane Sulfonic Acid (MSA) is employed in polymerization processes.
Methane Sulfonic Acid (MSA) catalyzes the production of resins and plastics.
Methane Sulfonic Acid (MSA) is used in phenolic and melamine resin synthesis.

Methane Sulfonic Acid (MSA) is incorporated in electroplating formulations.
Methane Sulfonic Acid (MSA) provides excellent metal deposition in tin and lead plating.
Methane Sulfonic Acid (MSA) improves brightness and uniformity of coatings.

Methane Sulfonic Acid (MSA) is used in pharmaceuticals as a catalyst.
Methane Sulfonic Acid (MSA) is employed in the preparation of active pharmaceutical ingredients (APIs).
Methane Sulfonic Acid (MSA) is used in salt formation for improved drug solubility.

Methane Sulfonic Acid (MSA) is applied in biodiesel production.
Methane Sulfonic Acid (MSA) enhances efficiency in esterification of free fatty acids.
Methane Sulfonic Acid (MSA) provides a greener alternative to mineral acids in biofuel synthesis.

Methane Sulfonic Acid (MSA) is used in oilfield chemicals.
Methane Sulfonic Acid (MSA) is employed as a catalyst in enhanced oil recovery formulations.
Methane Sulfonic Acid (MSA) improves stability of drilling fluids.

Methane Sulfonic Acid (MSA) is used in electronics manufacturing.
Methane Sulfonic Acid (MSA) is applied in electrochemical processes for semiconductors.
Methane Sulfonic Acid (MSA) ensures precise metal finishing in microelectronics.

Methane Sulfonic Acid (MSA) is incorporated into cleaning and descaling agents.
Methane Sulfonic Acid (MSA) dissolves oxides and scales without strong corrosiveness.
Methane Sulfonic Acid (MSA) is safe for stainless steel and sensitive alloys.

Methane Sulfonic Acid (MSA) is used in electroplating.
Methane Sulfonic Acid (MSA) serves as an electrolyte in metal deposition.
Methane Sulfonic Acid (MSA) enhances efficiency in tin and lead plating.

Methane Sulfonic Acid (MSA) is applied in gold plating.
Methane Sulfonic Acid (MSA) ensures smooth deposition of gold layers.
Methane Sulfonic Acid (MSA) improves uniformity of precious metal coatings.

Methane Sulfonic Acid (MSA) is used in catalyst preparation.
Methane Sulfonic Acid (MSA) acts as an acid catalyst in esterification reactions.
Methane Sulfonic Acid (MSA) supports polymerization processes.

Methane Sulfonic Acid (MSA) is incorporated in pharmaceutical synthesis.
Methane Sulfonic Acid (MSA) is used in the production of active pharmaceutical ingredients.
Methane Sulfonic Acid (MSA) provides mild reaction conditions for drug intermediates.

Methane Sulfonic Acid (MSA) is applied in alkylation reactions.
Methane Sulfonic Acid (MSA) enhances selectivity in organic synthesis.
Methane Sulfonic Acid (MSA) replaces stronger mineral acids in fine chemicals.

Methane Sulfonic Acid (MSA) is used in the production of biodiesel.
Methane Sulfonic Acid (MSA) catalyzes transesterification of oils and fats.
Methane Sulfonic Acid (MSA) supports renewable fuel technologies.

Methane Sulfonic Acid (MSA) is applied in polymer manufacturing.
Methane Sulfonic Acid (MSA) catalyzes the formation of specialty resins.
Methane Sulfonic Acid (MSA) improves polymerization yield.

Methane Sulfonic Acid (MSA) is used in cleaning formulations.
Methane Sulfonic Acid (MSA) removes scale and rust from industrial equipment.
Methane Sulfonic Acid (MSA) provides eco-friendly descaling alternatives.

Methane Sulfonic Acid (MSA) is incorporated in electronics.
Methane Sulfonic Acid (MSA) is used in etching and surface treatment.
Methane Sulfonic Acid (MSA) supports high-purity circuit board processing.

Methane Sulfonic Acid (MSA) is applied in agrochemicals.
Methane Sulfonic Acid (MSA) acts as an intermediate in pesticide production.
Methane Sulfonic Acid (MSA) supports synthesis of herbicide formulations.

Methane Sulfonic Acid (MSA) is used in laboratory research.
Methane Sulfonic Acid (MSA) serves as a strong, non-oxidizing acid.

Methane Sulfonic Acid (MSA) provides reproducible results in controlled experiments.
Methane Sulfonic Acid (MSA) is used in electrorefining.

Methane Sulfonic Acid (MSA) provides stable electrolytes for metal recovery.
Methane Sulfonic Acid (MSA) enables efficient separation of non-ferrous metals.

Methane Sulfonic Acid (MSA) is applied in tin-lead solder plating.
Methane Sulfonic Acid (MSA) ensures uniform coating thickness.
Methane Sulfonic Acid (MSA) enhances solder joint reliability.

Methane Sulfonic Acid (MSA) is used in precious metal recovery.
Methane Sulfonic Acid (MSA) dissolves gold and silver salts in refining.

Methane Sulfonic Acid (MSA) supports eco-friendly extraction methods.
Methane Sulfonic Acid (MSA) is applied in battery technology.

Methane Sulfonic Acid (MSA) is used in flow battery electrolytes.
Methane Sulfonic Acid (MSA) enhances charge and discharge efficiency.

Methane Sulfonic Acid (MSA) is incorporated in catalyst systems.
Methane Sulfonic Acid (MSA) replaces strong mineral acids in acid catalysis.

Methane Sulfonic Acid (MSA) supports homogeneous and heterogeneous catalysis.
Methane Sulfonic Acid (MSA) is used in esterification reactions.
Methane Sulfonic Acid (MSA) catalyzes production of flavor esters.

Methane Sulfonic Acid (MSA) improves selectivity in chemical synthesis.
Methane Sulfonic Acid (MSA) is applied in polymer modification.

Methane Sulfonic Acid (MSA) catalyzes crosslinking of specialty polymers.
Methane Sulfonic Acid (MSA) enhances performance of engineering plastics.

Methane Sulfonic Acid (MSA) is used in pharmaceutical intermediates.
Methane Sulfonic Acid (MSA) supports synthesis of analgesics and antihypertensives.
Methane Sulfonic Acid (MSA) provides controlled reaction conditions for sensitive drugs.

Methane Sulfonic Acid (MSA) is incorporated in herbicide production.
Methane Sulfonic Acid (MSA) is used to synthesize sulfonylurea herbicides.

Methane Sulfonic Acid (MSA) improves yield of agrochemical formulations.
Methane Sulfonic Acid (MSA) is applied in fine chemicals.

Methane Sulfonic Acid (MSA) supports synthesis of dyes and pigments.
Methane Sulfonic Acid (MSA) ensures reproducibility in specialty chemicals.

Methane Sulfonic Acid (MSA) is used in the fragrance industry.
Methane Sulfonic Acid (MSA) catalyzes reactions in aroma compound synthesis.
Methane Sulfonic Acid (MSA) provides high-purity intermediates for perfumery.

Methane Sulfonic Acid (MSA) is incorporated in biofuel research.
Methane Sulfonic Acid (MSA) is used as a catalyst in biomass conversion.

Methane Sulfonic Acid (MSA) supports development of green energy technologies.
Methane Sulfonic Acid (MSA) is applied in descaling agents.

Methane Sulfonic Acid (MSA) removes mineral deposits from heat exchangers.
Methane Sulfonic Acid (MSA) provides an alternative to hydrochloric acid cleaners.

Methane Sulfonic Acid (MSA) is used in microelectronics.
Methane Sulfonic Acid (MSA) acts as a surface treatment agent.
Methane Sulfonic Acid (MSA) improves adhesion of thin film layers.

Methane Sulfonic Acid (MSA) is applied in laboratory analysis.
Methane Sulfonic Acid (MSA) serves as a standard strong acid in titrations.
Methane Sulfonic Acid (MSA) is used in high-performance liquid chromatography.

DESCRIPTION

Methane Sulfonic Acid (MSA) is a clear, colorless to slightly yellow liquid.
Methane Sulfonic Acid (MSA) is a strong organic sulfonic acid.

Methane Sulfonic Acid (MSA) has the CAS number 75-75-2.
Methane Sulfonic Acid (MSA) has the EC number 200-898-6.

Methane Sulfonic Acid (MSA) has the molecular formula CH4O3S.
Methane Sulfonic Acid (MSA) has a molecular weight of 96.10 g/mol.

Methane Sulfonic Acid (MSA) appears as a colorless to pale yellow liquid.
Methane Sulfonic Acid (MSA) is highly soluble in water.

Methane Sulfonic Acid (MSA) is non-volatile and thermally stable.
Methane Sulfonic Acid (MSA) is considered less corrosive than mineral acids.

Methane Sulfonic Acid (MSA) is biodegradable and environmentally friendly.
Methane Sulfonic Acid (MSA) is preferred as a green alternative to other strong acids.
Methane Sulfonic Acid (MSA) does not release harmful byproducts upon decomposition.

Methane Sulfonic Acid (MSA) is stable under normal storage conditions.
Methane Sulfonic Acid (MSA) is compatible with a wide range of solvents.
Methane Sulfonic Acid (MSA) requires careful handling due to strong acidity.

It is compatible with many industrial formulations.
MSA is widely adopted in industries seeking sustainable acid alternatives.

PROPERTIES

Appearance: Clear, colorless to slightly yellow liquid
Odor: Odorless or faint characteristic
Density: 1.48 g/cm³ (at 20°C)
Melting Point: 20°C
Boiling Point: 167°C (decomposes)
Flash Point: Non-flammable
Solubility: Miscible with water, alcohols, polar solvents
pKa: -1.9 (strong acid)
Reactivity: Strong acid, reacts with bases, amines, and oxidizers
Storage Temperature: Store at 10–30°C in tightly sealed containers

FIRST AID

Inhalation:
Move to fresh air immediately.
Seek medical attention if breathing difficulty occurs.

Skin Contact:
Wash thoroughly with soap and water.
Remove contaminated clothing.
Seek medical help if irritation persists.

Eye Contact:
Flush with plenty of water for at least 15 minutes.
Seek immediate medical attention.

Ingestion:
Rinse mouth with water.
Do not induce vomiting.
Seek immediate medical attention.

Note to Physicians:
Treat symptomatically.
Corrosive acid; may cause burns to mucous membranes and GI tract.

HANDLING AND STORAGE

Handling:
Wear protective gloves, goggles, and clothing.
Avoid inhalation, ingestion, and contact with skin and eyes.

Ventilation:
Use in well-ventilated areas or with local exhaust.

Avoidance:
Avoid contact with strong oxidizers and reactive metals.
Do not eat, drink, or smoke while handling.

Spill and Leak Procedures:
Neutralize with alkaline absorbent (lime, sodium carbonate).
Collect and dispose of according to local regulations.

Storage:
Store in corrosion-resistant containers.
Keep tightly sealed in a cool, dry, and ventilated place.
Protect from moisture, heat, and direct sunlight.