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METHOXYPOLYETHYLENE GLYCOL (MPEG)


Methoxypolyethylene Glycol (MPEG) is a nonionic polymer derived from polyethylene glycol, terminated with a methoxy group, widely used as a surfactant, dispersant, emulsifier, and intermediate in chemical synthesis.
Methoxypolyethylene Glycol (MPEG) is valued for its water solubility, low toxicity, biocompatibility, and ability to modify surfaces and molecules to improve stability and performance.
Methoxypolyethylene Glycol (MPEG) is employed in pharmaceuticals, personal care products, industrial formulations, and polymer modification applications.

CAS Number: 9004-74-4
EC Number: 618-363-4
Molecular Formula: CH3O-(CH2CH2O)n-H
Molecular Weight: Variable depending on polymer chain length (commonly 350–5000 g/mol)

Synonyms: Methoxypolyethylene Glycol, MPEG, Polyethylene Glycol Monomethyl Ether, PEG Monomethyl Ether, Methoxy-capped Polyethylene Glycol, Polyethylene Glycol Methyl Ether, PEG-Methyl Ether, Methyl-terminated Polyethylene Glycol, MPEG for Pharmaceuticals, MPEG for Cosmetics, MPEG for Coatings, MPEG for Adhesives, MPEG for Dispersions, MPEG Surface Modifier, MPEG Intermediate, MPEG Binder, MPEG Stabilizer, MPEG Solubilizer, MPEG Lubricant

APPLICATIONS


Methoxypolyethylene Glycol (MPEG) is used as a raw material in the production of polycarboxylate superplasticizers for high-performance concrete.
Methoxypolyethylene Glycol (MPEG) improves water reduction and flowability in cement-based formulations.
Methoxypolyethylene Glycol (MPEG) enhances workability retention in construction applications.

Methoxypolyethylene Glycol (MPEG) is employed as a surfactant and dispersant in pigment and dye formulations.
Methoxypolyethylene Glycol (MPEG) improves color uniformity and stability in coatings and paints.
Methoxypolyethylene Glycol (MPEG) prevents pigment agglomeration in aqueous dispersions.

Methoxypolyethylene Glycol (MPEG) is incorporated into pharmaceuticals for drug conjugation (PEGylation).
Methoxypolyethylene Glycol (MPEG) improves drug solubility, stability, and bioavailability.
Methoxypolyethylene Glycol (MPEG) extends the circulation time of biopharmaceuticals in the body.

Methoxypolyethylene Glycol (MPEG) is used in cosmetics and personal care products as an emulsifier and thickener.
Methoxypolyethylene Glycol (MPEG) provides a smooth texture in creams and lotions.
Methoxypolyethylene Glycol (MPEG) acts as a moisturizer and skin-conditioning agent.

Methoxypolyethylene Glycol (MPEG) is utilized in adhesive formulations to enhance flexibility and reduce brittleness.
Methoxypolyethylene Glycol (MPEG) improves wetting and adhesion properties in waterborne adhesives.
Methoxypolyethylene Glycol (MPEG) increases compatibility between polar and nonpolar components.

Methoxypolyethylene Glycol (MPEG) is applied in polymer modification to create hydrophilic surfaces.
Methoxypolyethylene Glycol (MPEG) improves antifouling properties in marine coatings.
Methoxypolyethylene Glycol (MPEG) is used in biomedical devices for biocompatibility enhancement.

Methoxypolyethylene Glycol (MPEG) is used in lubricant formulations as a friction-reducing additive.
Methoxypolyethylene Glycol (MPEG) provides lubrication in water-based metalworking fluids.
Methoxypolyethylene Glycol (MPEG) improves thermal stability in specialty lubricants.

Methoxypolyethylene Glycol (MPEG) is used in agricultural formulations as a dispersant and wetting agent.
Methoxypolyethylene Glycol (MPEG) improves the spreading of pesticides and herbicides.
Methoxypolyethylene Glycol (MPEG) enhances the performance of foliar nutrient sprays.

Methoxypolyethylene Glycol (MPEG) is applied in textile processing as a softener and antistatic agent.
Methoxypolyethylene Glycol (MPEG) improves dye penetration and fabric smoothness.
Methoxypolyethylene Glycol (MPEG) reduces static buildup in synthetic fibers.

Methoxypolyethylene Glycol (MPEG) is used as a non-ionic surfactant in personal care formulations to provide emulsification and stabilization.
Methoxypolyethylene Glycol (MPEG) is incorporated into shampoos and conditioners to improve texture and spreadability.
Methoxypolyethylene Glycol (MPEG) is applied in skin creams and lotions for enhanced moisture retention.

Methoxypolyethylene Glycol (MPEG) is used as a reactive intermediate in polyurethane manufacturing for flexible foam production.
Methoxypolyethylene Glycol (MPEG) is incorporated into thermoplastic polyurethane elastomers for improved elasticity.
Methoxypolyethylene Glycol (MPEG) is applied in rigid polyurethane foams to enhance dimensional stability.

Methoxypolyethylene Glycol (MPEG) is used in pharmaceutical formulations as a solubilizer for poorly water-soluble drugs.
Methoxypolyethylene Glycol (MPEG) is incorporated into drug delivery systems for controlled-release applications.
Methoxypolyethylene Glycol (MPEG) is applied in ointments to improve consistency and absorption.

Methoxypolyethylene Glycol (MPEG) is used in construction chemicals as a raw material for superplasticizers in concrete.
Methoxypolyethylene Glycol (MPEG) is incorporated into polycarboxylate ether superplasticizers to improve workability.
Methoxypolyethylene Glycol (MPEG) is applied in cement admixtures to increase slump retention.

Methoxypolyethylene Glycol (MPEG) is used in textile finishing to impart softness and antistatic properties.
Methoxypolyethylene Glycol (MPEG) is incorporated into fabric softeners for improved hand feel.
Methoxypolyethylene Glycol (MPEG) is applied in antistatic agents for synthetic fibers.

Methoxypolyethylene Glycol (MPEG) is used in paints and coatings as a dispersing agent for pigments.
Methoxypolyethylene Glycol (MPEG) is incorporated into water-based paints for viscosity control.
Methoxypolyethylene Glycol (MPEG) is applied in anti-foaming agents to improve surface appearance.

Methoxypolyethylene Glycol (MPEG) is used in agrochemical formulations as a dispersant for active ingredients.
Methoxypolyethylene Glycol (MPEG) is incorporated into pesticide emulsions for better spray uniformity.
Methoxypolyethylene Glycol (MPEG) is applied in herbicide formulations for improved solubility.

Methoxypolyethylene Glycol (MPEG) is used in adhesives and sealants to improve flow and wetting properties.
Methoxypolyethylene Glycol (MPEG) is incorporated into hot melt adhesives for better flexibility.
Methoxypolyethylene Glycol (MPEG) is applied in pressure-sensitive adhesives to enhance tack.

Methoxypolyethylene Glycol (MPEG) is used in metalworking fluids as a lubricity enhancer.
Methoxypolyethylene Glycol (MPEG) is incorporated into cutting fluids to reduce friction.
Methoxypolyethylene Glycol (MPEG) is applied in corrosion inhibitor formulations.

Methoxypolyethylene Glycol (MPEG) is used in oilfield chemicals as a component of demulsifiers.
Methoxypolyethylene Glycol (MPEG) is incorporated into drilling fluids to improve rheology.
Methoxypolyethylene Glycol (MPEG) is applied in enhanced oil recovery surfactant packages.

Methoxypolyethylene Glycol (MPEG) is used in inks as a humectant to prevent drying in printing equipment.
Methoxypolyethylene Glycol (MPEG) is incorporated into inkjet formulations to control droplet formation.
Methoxypolyethylene Glycol (MPEG) is applied in flexographic inks for improved print quality.

Methoxypolyethylene Glycol (MPEG) is used in the production of specialty polymers for biomedical applications.
Methoxypolyethylene Glycol (MPEG) is incorporated into hydrogels for wound care products.
Methoxypolyethylene Glycol (MPEG) is applied in tissue engineering scaffolds.

Methoxypolyethylene Glycol (MPEG) is used in food packaging films as a processing aid.
Methoxypolyethylene Glycol (MPEG) is incorporated into biodegradable plastics to enhance flexibility.
Methoxypolyethylene Glycol (MPEG) is applied in edible coatings for moisture control.

Methoxypolyethylene Glycol (MPEG) is used in cleaning products as a solubilizing and wetting agent.
Methoxypolyethylene Glycol (MPEG) is incorporated into dishwashing liquids to improve grease removal.
Methoxypolyethylene Glycol (MPEG) is applied in surface cleaners for uniform coverage.

DESCRIPTION


Methoxypolyethylene Glycol (MPEG) is a clear to slightly hazy viscous liquid or waxy solid depending on molecular weight.
Methoxypolyethylene Glycol (MPEG) is a polyether compound with a methoxy terminal group and a polyethylene glycol backbone.
Methoxypolyethylene Glycol (MPEG) is non-ionic, offering compatibility with a wide range of formulation types.

Methoxypolyethylene Glycol (MPEG) is soluble in water and many polar organic solvents.
Methoxypolyethylene Glycol (MPEG) is stable under normal storage conditions and exhibits low volatility.
Methoxypolyethylene Glycol (MPEG) is resistant to hydrolysis under neutral conditions.

Methoxypolyethylene Glycol (MPEG) is produced by reacting polyethylene glycol with methanol under catalytic conditions.
Methoxypolyethylene Glycol (MPEG) is available in a range of molecular weights to suit different applications.

Methoxypolyethylene Glycol (MPEG) is low in toxicity and generally regarded as safe in approved uses.
Methoxypolyethylene Glycol (MPEG) is stored in sealed containers away from moisture to maintain product quality.

Methoxypolyethylene Glycol (MPEG) is a clear, viscous liquid or waxy solid depending on molecular weight.
It is a polyether polymer with a methoxy end group, making it nonionic and stable across a wide pH range.
Methoxypolyethylene Glycol (MPEG) is soluble in water and many polar organic solvents.

The methoxy termination reduces hydrogen bonding compared to PEG, offering lower viscosity and improved flow in formulations.
Methoxypolyethylene Glycol (MPEG) is chemically stable under normal conditions and resistant to hydrolysis.
It is non-irritating, non-volatile, and considered safe for use in food, cosmetic, and pharmaceutical applications.

Methoxypolyethylene Glycol (MPEG) is synthesized by the polymerization of ethylene oxide with methanol as an initiator.
It is available in different molecular weights to suit specific applications, from low-viscosity liquids to high-melting solids.

PROPERTIES


Chemical Formula: CH3O-(CH2CH2O)n-H
Molecular Weight: 350–5000 g/mol (depending on grade)
Common Name: Methoxypolyethylene Glycol
Appearance: Clear liquid to white waxy solid
Odor: Odorless or faint
Density: ~1.1–1.2 g/cm³
Melting Point: -15°C (low MW) to >60°C (high MW)
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol, and polar organic solvents
pH: Neutral
Reactivity: Stable under normal conditions; incompatible with strong oxidizing agents
Chemical Stability: Excellent under ambient storage conditions
Storage Temperature: Store in a cool, dry, well-ventilated area

FIRST AID


Inhalation:
Move to fresh air.
Seek medical attention if respiratory symptoms develop.

Skin Contact:
Wash thoroughly with soap and water.
Seek medical advice if irritation occurs.

Eye Contact:
Rinse with plenty of water for at least 15 minutes.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if large quantities are ingested.

Note to Physicians:
Treat symptomatically; no specific antidote.

HANDLING AND STORAGE


Handling:
Wear suitable protective clothing, gloves, and safety glasses.
Avoid prolonged skin contact.
Ensure adequate ventilation during handling.

Storage:
Store in sealed containers in a cool, dry place away from heat and strong oxidizers.
Protect from moisture contamination.

Spill and Leak Procedures:
Contain spill and absorb with inert material.
Clean with water and detergent.
Dispose of according to local regulations.


 

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