METHYL ETHYL KETOXIME (MEKO)

Methyl Ethyl Ketoxime (MEKO) is a colorless or light yellow oily transparent liquid that has strong complexation with metal ions and is volatile in the air. 
Methyl Ethyl Ketoxime (MEKO) can react with hydrochloric acid and sulfuric acid to form methyl ethyl ketone.
Methyl Ethyl Ketoxime (MEKO) knows as a novel oxygen scavenger is disclosed in the U.S. and patented by Drew Chemical Company in 1984. 

CAS Number: 96-29-7
Molecular Formula: C4H9NO
Molecular Weight: 87.12
EINECS Number: 406-930-7

MEK-oxime,Butanone oxime,2-BUTANONE OXIME2-Butanone oxime, 2-Butanone, oxime, 2-butanona, oxima, 4-01-00-03250 (Beilstein Handbook Reference), 96-29-7, BRN 1698241, Butanone oxime, Butanone oxime; (Ethyl methyl ketoxime), C4-H9-N-O, C4H9NO, CCRIS 1382, EC 202-496-6, EINECS 202-496-6, Ethyl methyl ketone oxime, Ethyl methyl ketoxime, Ethyl-methylketonoxim, Ethyl-methylketonoxim [Czech], HSDB 8043, MEK-oxime, MEKO, Methyl ethyl ketone oxime, Methyl ethyl ketoxime, NA1993, NSC 442, Skino #2, Troykyd anti-skin B, UN1993, UNII-51YGE935U9, USAF AM-3, USAF EK-906

Methyl Ethyl Ketoxime (MEKO) displays low toxicity, efficiency, fast-performance, and a blunt protective effects. 
In Europe and other developed countries it has been widely applied, and China it is also successfully developed in the nineties, and has been successful in promotion.
Oxygen scavenging performance: oxime compound is an organic compound with an oxime group. 

Oxime compounds are currently used for boiler shutdown protection and oxygen mainly acetaldehyde oxime, Methyl Ethyl Ketoxime (MEKO) and methyl ethyl ketone oxime.
Methyl Ethyl Ketoxime (MEKO)s have a strong reduction, easy to react with oxygen. When put in a wide temperature and pressure ranges, oximes has good oxygen scavenging performance. 
The optimum temperature range is 138~336 ℃, and pressure range is 0.3~13.7Mpa. 

According to comparative experiments, under the same conditions, the rate of oxygen and oxygen efficiency oximes is higher than that of hydrazine.
Corrosion and passivation: oximes can restore high iron and copper oxide into suboxide, which can be a good solution in the steel magnetic oxide film formed on the surface of the metal surface passivation plays well, corrosion inhibition. 
Where in dimethylketoximino is the best, using the minimum amount required. 

According to comparative experiments, oxime compounds having the same passivation, corrosion inhibition hydrazine, can significantly reduce the iron content in solution at high temperature and pressure conditions. 
The steel has a protective effect, among which the dimethylketoximino is best, which requires the least amount. 
Meanwhile, oxime compounds have cleaning actions to copper corrosion products deposited in the pipeline, economizer, etc., which is in the initial period of oximes. 

This is the reason why furnace copper water content is significantly higher.
Volatile: the volatile degree of oxime compounds is higher than that of hydrazine, DEHA, morpholine, cyclohexylamine, etc. 
Methyl Ethyl Ketoxime (MEKO) is close to the volatility of NH3. When the steam condenses, highly volatile oxygen scavenger will has a certain amount of condensation agent which is dissolved in water, therefore, helpful to protect the condensate system metal material.

Decomposition: By experiments under the high temperature and pressure conditions, the decomposition products of oxime compound is NH3, N2, H2O, trace of acetic acid, formic acid produces, no adverse effects on water vapor system.
Low toxicity: based on the data comparison of LD50, the LD50 for hydrazine is 290mg/kg, acetaldehyde oxime is 1900mg/kg, methyl ethyl ketone oxime is 2800mg/kg, dimethylket oximino 5500mg/kg. 
So the toxicity of hydrazine is very strong, and toxicity of oxime compound is very small. 

Methyl Ethyl Ketoxime (MEKO) belongs to low toxicity compounds. Test through the skin and mucous membrane contact with oxygen scavengers showed no significant oximes oxygen scavenger irritation and damage, but hydrazine causes damage of skin irritation, erosion, mucosal hyperemia.
Methyl Ethyl Ketoxime (MEKO) is the organic compound with the formula C2H5C(NOH)CH3. 
This colourless liquid is the oxime derivative of methyl ethyl ketone. 

Methyl Ethyl Ketoxime (MEKO), as it is called in the paint industry, is used to suppress "skinning" of paints: the formation of a skin on paint before it is used. 
Methyl Ethyl Ketoxime (MEKO) is particularly used in alkyd paints. 
Methyl Ethyl Ketoxime (MEKO) functions by binding the drying agents, metal salts that catalyze the oxidative crosslinking of drying oils. 

Once the paint is applied to a surface, Methyl Ethyl Ketoxime (MEKO) evaporates, thereby allowing the drying process to proceed. 
Other antiskinning agents have been used, including phenolic antioxidants (E.G butylated hydroxytoluene), but these tend to yellow the paint.
This oxime is also used in some types of RTV silicones.

Methyl Ethyl Ketoxime (MEKO) is a chemical compound with the molecular formula C3H7NO. 
Methyl Ethyl Ketoxime (MEKO) is also known as ethyl methyl ketone oxime or 2-Butanone oxime. 
Methyl Ethyl Ketoxime (MEKO) is a clear, colorless to pale yellow liquid with a characteristic odor.

Methyl Ethyl Ketoxime (MEKO) is primarily used as an additive in various industrial processes, particularly in coatings, adhesives, and sealants. 
Methyl Ethyl Ketoxime (MEKO) functions as an anti-skinning agent, meaning it prevents the formation of a skin on the surface of these products when exposed to air. 
This helps to maintain the quality and usability of the product over time by preventing surface drying and oxidation.

Methyl Ethyl Ketoxime (MEKO) is obtained by the reaction of butanone and hydroxylamine hydrochloride. 
Methyl Ethyl Ketoxime (MEKO) can also be synthesized by the reaction between butanone and hydroxylamine sulfate.
Methyl Ethyl Ketoxime (MEKO) is sensitive to heat. Has exploded at least twice when heated in the presence of acidic impurities. 

Mixtures with strong acids may explode. 
Reacts with sulfuric acid to form an explosive product .
Methyl Ethyl Ketoxime (MEKO) is primarily used as an anti-skinning agent for oil and latex paints and coatings. 

Methyl Ethyl Ketoxime (MEKO) is also widely used as an isocyanate-blocking agent in priming automobiles (electrodeposition coating) for paint jobs and as a curing agent for silicon rubber due to its outstanding water and heat resistance.
Methyl Ethyl Ketoxime (MEKO) or butanone oxime, is a substance used to prevent the skinning of some solvent-borne paints in the container or prior to use. 
Once the paint is applied to a surface, the Methyl Ethyl Ketoxime (MEKO) evaporates, thereby allowing the drying process to proceed. 

Historically, Methyl Ethyl Ketoxime (MEKO) has been used by the industry for many years as it is a very effective anti-skinning agent.
Methyl Ethyl Ketoxime (MEKO), commonly referred to as MEKO, is a chemical compound with the molecular formula C5H11NO. 
Methyl Ethyl Ketoxime (MEKO) is categorised as an oxime Crosslinker for silicones and is characterised by its distinctive odour. 

Methyl Ethyl Ketoxime (MEKO) is a colourless to pale yellow liquid that is soluble in water and commonly used for its reactivity with compounds containing isocyanate groups. 
Methyl Ethyl Ketoxime (MEKO) has several valuable applications across different industries.
Methyl Ethyl Ketoxime (MEKO) is often used as an anti-skinning agent in coatings and paints. 

Methyl Ethyl Ketoxime (MEKO) prevents the formation of a skin or surface film when the product is exposed to air, thus extending the shelf life of these materials.
In the production of adhesives and sealants, Methyl Ethyl Ketoxime (MEKO) acts as a crosslinking agent. 
Methyl Ethyl Ketoxime (MEKO) helps improve the durability and performance of these products.

Methyl Ethyl Ketoxime (MEKO) is employed as an inhibitor in industrial processes involving isocyanate compounds, such as the production of polyurethane foams. 
Methyl Ethyl Ketoxime (MEKO) stabilizes these compounds, preventing premature reactions.
Methyl Ethyl Ketoxime (MEKO) Some silicone sealants use MEKO as a curing agent, aiding in the hardening and setting of the sealant.

Methyl Ethyl Ketoxime (MEKO) is an essential chemical used as an anti-skinning agent in paints and lacquers, as a blocking-agent for isocyanate in polyurethanes, and in the manufacture of oxime silanes (that are used as crosslinkers for silicone sealants).
Methyl Ethyl Ketoxime (MEKO) is a high production volume (HPV) chemical produced at over one million pounds annually.

AdvanSix has established a provisional occupational exposure limit of 3 ppm (10 mg/m3) for an 8-hour timeweighted average and a short-term exposure limit of 10 ppm for use in worksite safety programs.
Methyl Ethyl Ketoxime (MEKO) is a clear, colorless, combustible liquid.
Methyl Ethyl Ketoxime (MEKO) is severely irritating to eyes. 

If Methyl Ethyl Ketoxime (MEKO) gets into the eyes, immediately flush with plenty of water and seek medical attention to avoid serious damage. 
Methyl Ethyl Ketoxime (MEKO) is moderately toxic in the unlikely event of ingestion. 
Ingesting or breathing  high concentrations may cause harmful, but reversible, effects on the blood (anemia) and inhalation can irritate nasal passages. 

Methyl Ethyl Ketoxime (MEKO) is slightly irritating to skin and can be absorbed through the skin to cause harmful effects on the blood and nervous system. 
Getting Methyl Ethyl Ketoxime (MEKO) on the skin may cause an allergic response in certain individuals. 
Methyl Ethyl Ketoxime (MEKO) is rapidly metabolized and eliminated from the body. MEKO does not cause harmful effects on reproduction or development.

Male rodents developed liver tumors when repeatedly exposed during their lifetime to high concentrations of Methyl Ethyl Ketoxime (MEKO).
These tumors developed late in life and did not affect survival. 
Methyl Ethyl Ketoxime (MEKO) is not genotoxic, pointing to a threshold mechanism for cancer development (i.e., a “safe level” below which cancer will not occur: a level well above typical exposures). Therefore, the human risk of cancer is low.

Methyl Ethyl Ketoxime (MEKO) has low toxicity to aquatic organisms, upon either single or repeated exposure.
Methyl Ethyl Ketoxime (MEKO) has minimal potential to accumulate in the bodies of humans or animals. 
Methyl Ethyl Ketoxime (MEKO) is readily biodegradable and will not persist in the environment.

Methyl Ethyl Ketoxime (MEKO), also known as 2-butanone oxime or MEK-oxime, is an industrial antioxidant used as an antiskinning agent in paints. 
Methyl Ethyl Ketoxime (MEKO) is also used as a blocking agent for urethane polymers, as a corrosion inhibitor in industrial boilers, and can be found in some adhesives, caulking products and repair products that may be used by
consumers.
Because of the wide range of industrial and consumer uses for this chemical, one might expect exposures to both workers and consumers. 

Acts as a curing agent. 
Offers outstanding water resistance and heat resistance.
Recommended for silicone based rubbers.

Methyl Ethyl Ketoxime (MEKO) is the organic compound with the formula C2H5C(NOH)CH3. 
This colorless liquid is the oxime derivative of methyl ethyl ketone. 
Methyl Ethyl Ketoxime (MEKO), as it is called in the paint industry, is used to suppress “skinning” of paints: the formation of a skin on paint before it is used. 

Methyl Ethyl Ketoxime (MEKO) functions by binding the drying agents, metal salts that catalyze the oxidative crosslinking of drying oils. 
Once the paint is applied to a surface, Methyl Ethyl Ketoxime (MEKO) evaporates, thereby allowing the drying process to proceed.
Methyl Ethyl Ketoxime (MEKO) is a high-efficiency anti-skinning agent used for air-drying paints, inks and coatings.

Methyl Ethyl Ketoxime (MEKO) is also used to improve the shelf life of silicone adhesives and sealants, and the functionality of polyurethane coatings.
Methyl Ethyl Ketoxime (MEKO) is produced to meet the low moisture and high assay standards that formulators require.

Melting point: -30 °C
Boiling point: 59-60 °C15 mm Hg(lit.)
Density: 0.924 g/mL at 25 °C(lit.)
vapor density: 3 (vs air)
vapor pressure: <8 mm Hg ( 20 °C)
refractive index: n20/D 1.442(lit.)
Flash point: 140 °F
solubility: water: soluble100g/L at 25°C
form: Liquid
pka: pK1:12.45 (25°C)
color: Clear colorless to pale yellow
Water Solubility: 114 g/L (20 ºC)
BRN: 1698241
Dielectric constant: 3.4（20℃）
Stability: Stable. Combustible. Incompatible with strong oxidizing agents. May react with strong acids to form an explosive material.
InChIKey: WHIVNJATOVLWBW-SNAWJCMRSA-N
LogP: 0.63 at 25℃

Methyl Ethyl Ketoxime (MEKO) is a ketoxime compound derived from the reaction of methyl ethyl ketone (MEK) with hydroxylamine. 
Methyl Ethyl Ketoxime (MEKO) has a boiling point of approximately 152-154°C and is soluble in water, alcohols, and many organic solvents.
Methyl Ethyl Ketoxime (MEKO) is widely used as an anti-skinning agent in coatings, paints, and inks to prevent the formation of a skin or surface film when these products are exposed to air. 

This helps to prolong the shelf life of the product and maintain its workability.
Methyl Ethyl Ketoxime (MEKO) is also utilized as a reagent in oximation reactions, where it reacts with carbonyl compounds (such as aldehydes and ketones) to form oxime derivatives. 
This reaction is commonly used in organic synthesis for functional group transformations and the synthesis of various compounds.

In addition to its anti-skinning properties, Methyl Ethyl Ketoxime (MEKO) can also act as a polymerization inhibitor in certain systems, helping to prevent unwanted polymerization reactions that can lead to product degradation or quality issues.
Methyl Ethyl Ketoxime (MEKO) is widely used in industry, it is important to handle it with care due to its potential health hazards. 
Inhalation or skin exposure to Methyl Ethyl Ketoxime (MEKO) vapor or liquid can cause irritation to the respiratory system, eyes, and skin. 

Prolonged or repeated exposure may lead to more serious health effects. 
Proper safety measures, including adequate ventilation and personal protective equipment, should be employed when handling MEKO.
Methyl Ethyl Ketoxime (MEKO) is regulated in various jurisdictions, and its use may be subject to restrictions and safety guidelines. 

Methyl Ethyl Ketoxime (MEKO) is important for users to be aware of relevant regulations and ensure compliance with safety standards when handling MEKO-containing products.
Methyl Ethyl Ketoxime (MEKO) is the organic compound with the formula C2H5C(NOH)CH3. 
This colourless liquid is the oxime derivative of methyl ethyl ketone. 

Methyl Ethyl Ketoxime (MEKO), as it is called in the paint industry, is used to suppress "skinning" of paints: the formation of a skin on paint before it is used.
With suitable precautions, to 1 liter of the sodium hydroxylamine di­sulfonate solution from Preparation 2-1 (approx. 1.2 moles) is added 72 gm (1 mole) of methyl ethyl ketone.
Then the reaction flask is wrapped with insulation and allowed to cool slowly for 12 hr.

After neutralization with 48% sodium hydroxide solution, the oxime is extracted from the reaction mixture with benzene. 
The benzene solution is distilled fractionally. 
Methyl Ethyl Ketoxime (MEKO) distills between 152° and 154°C; yield, 65 gm (75%).

Methyl Ethyl Ketoxime (MEKO) is incorporated into a range of products across different industries. 
Methyl Ethyl Ketoxime (MEKO) is added to paints and coatings as an anti-skinning agent, ensuring the product remains usable over time.
Methyl Ethyl Ketoxime (MEKO) is used as a crosslinking agent in adhesives and sealants, enhancing their performance and durability.

In the production of polyurethane foams, MEKO serves as an inhibitor to prevent premature reactions during processing.
Certain silicone sealants use Methyl Ethyl Ketoxime (MEKO) as a curing agent to facilitate the hardening process.
The short-term risks of Methyl Ethyl Ketoxime (MEKO) exposure when using oxime silicone sealants are associated with acute toxicity upon contact with the skin, eyes, or inhalation. 

At low concentrations resulting from oxime curing, skin contact may lead to mild skin irritation or trigger allergic dermal reactions. 
Eye contact is particularly severe, causing serious eye irritation upon exposure to fumes and irreversible eye damage upon concentrated contact. 
Although acute toxicity through inhalation is classified as low, it may still result in respiratory irritation, posing significant long-term exposure risks. 

Acute oral toxicity is low but is less relevant for sealant applications.
Methyl Ethyl Ketoxime (MEKO) also known as Butanone oxime (CAS number 96-29-7) is a substance that has been reclassified in UK and EU law as carcinogenic. 
Since 1st March 2022 this has resulted in mandatory labelling and classification of any products containing Methyl Ethyl Ketoxime (MEKO) sold on the general market. 

The EU REACH has also restricted the sale of any products containing this substance to the general public. 
This is not currently the case under UK REACH and therefore the restriction on supply to the general public does not apply in the UK.
Methyl Ethyl Ketoxime (MEKO), is utilized to eliminate a thick layer, typically a few millimeters thick, that forms on the surface of the paint. 

The application of anti-skinning in the paint industry becomes necessary when colors are exposed to air and oxygen, causing them to undergo changes and develop a thick layer. 
Consequently, incorporating anti-skinning agents into paints prevents the formation of these thick layers on the paint’s surface.
When the solvent in base colorants evaporates, it leaves behind a layer of substances in the remaining paint. 

The addition of this additive to the paint prevents the formation of this layer on the paint’s surface. 
Essentially, this substance inhibits the oxidative reaction of colorants with air inside the can, and it has no impact on viscosity, overall film stability, gloss, and other rheological properties of the color, both during storage and the drying phase.
The anti-oxidative mechanism of anti-skinning agents involves their rapid evaporation, reaching the paint surface. 

Its vapors cover the surface of the paint in the can and fill the gap between the oxygen present in the empty space of the container. 
The primary resins prone to skinning are alkyd resins, characterized by a specific structural form, followed by epoxy esters, urethane alkyd resins, and modified oils.

Uses Of Methyl Ethyl Ketoxime (MEKO):
Methyl ethyl ketoxime is mainly used as anti-skinning agent and silicon curing agent for alkyd resin coatings. 
Methyl Ethyl Ketoxime (MEKO) is used as an antioxidant to prevent skin formation, which is better than butyraldehyde oxime and cyclohexanone oxime.
For a variety of oil-based paint, alkyd paint, epoxy paint, such as esters during storage and transportation of anti-skinning process, also used as a curing agent silicon.

Methyl Ethyl Ketoxime (MEKO) was employed as reagent and solvent in the syntheses of ketoimine and 2,4-dipyridyl-1,3,5-triazapentadiene palladium(II) complexes. Methyl Ethyl Ketoxime (MEKO) was also used in the synthesis of novel acetaldiimine cobalt complex, [CoI2{((CH3CH2)(CH3)C=NO)2C(CH3)2}]. 
Methyl Ethyl Ketoxime (MEKO) is used primarily as an antiskinning agent in alkyd coating resins.

Methyl Ethyl Ketoxime (MEKO) is used in the following products: coating products.
Methyl Ethyl Ketoxime (MEKO) is used in the following areas: building & construction work.
Methyl Ethyl Ketoxime (MEKO) is used for the manufacture of: wood and wood products, pulp, paper and paper products, plastic products, fabricated metal products, electrical, electronic and optical equipment, machinery and vehicles and furniture.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Methyl Ethyl Ketoxime (MEKO) is used in the following products: coating products and polymers.
Release to the environment of Methyl Ethyl Ketoxime (MEKO) can occur from industrial use: formulation of mixtures.

Methyl Ethyl Ketoxime (MEKO) is used in the following products: coating products.
Methyl Ethyl Ketoxime (MEKO) has an industrial use resulting in manufacture of another substance (use of intermediates).
Methyl Ethyl Ketoxime (MEKO) is used in the following areas: formulation of mixtures and/or re-packaging.

Methyl Ethyl Ketoxime (MEKO) is used for the manufacture of: chemicals.
Release to the environment of Methyl Ethyl Ketoxime (MEKO) can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, manufacturing of the substance and formulation of mixtures.
Methyl Ethyl Ketoxime (MEKO) is widely used as an anti-skinning agent in coatings, paints, and varnishes to prevent the formation of a surface skin or film when these products are exposed to air. 

This helps to maintain the quality and usability of the coatings and prevents skinning in storage containers and on application surfaces.
In the printing industry, Methyl Ethyl Ketoxime (MEKO) serves as an anti-skinning agent in inks and printing varnishes to prevent drying and skinning on printing plates, rollers, and other equipment. 
Methyl Ethyl Ketoxime (MEKO) helps to ensure smooth printing operations and prevents blockages in printing machinery.

Methyl Ethyl Ketoxime (MEKO) is used in adhesive and sealant formulations to prevent skinning and drying of the product in storage containers and during application. 
Methyl Ethyl Ketoxime (MEKO) helps to maintain the workability and shelf life of adhesives and sealants, particularly those based on solvent-based or reactive chemistries.
Methyl Ethyl Ketoxime (MEKO) is employed as a reagent in organic synthesis for oximation reactions, where it reacts with carbonyl compounds (such as aldehydes and ketones) to form oxime derivatives. 

Oximation reactions are used in the synthesis of pharmaceuticals, agrochemicals, flavors, fragrances, and other specialty chemicals.
Methyl Ethyl Ketoxime (MEKO) can act as a polymerization inhibitor in certain systems to prevent unwanted polymerization reactions that can lead to product degradation or Methyl Ethyl Ketoxime (MEKO) is used in polymerizable monomers, resins, and other reactive systems to stabilize the formulation and extend its shelf life.

Methyl Ethyl Ketoxime (MEKO) may be used in cleaning formulations as a solvent or co-solvent for removing paints, varnishes, and coatings from equipment, surfaces, and tools. 
Its ability to dissolve and disperse coatings makes it useful in paint strippers and cleaning solutions for industrial and household applications.
Methyl Ethyl Ketoxime (MEKO) is employed in metal surface treatment processes, such as metal cleaning and degreasing, to remove contaminants and prepare the surface for painting, coating, or plating. 

Methyl Ethyl Ketoxime (MEKO) helps to dissolve oils, greases, and other residues from metal surfaces, improving adhesion and corrosion resistance.
Methyl Ethyl Ketoxime (MEKO) is commonly used in automotive coatings, including primers, basecoats, and clearcoats, to prevent skinning and drying during storage and application. 
Methyl Ethyl Ketoxime (MEKO) helps to maintain the viscosity and flow properties of the coatings, ensuring consistent coverage and finish.

In wood finishing products such as stains, varnishes, and lacquers, Methyl Ethyl Ketoxime (MEKO) serves as an anti-skinning agent to prevent surface drying and skinning. 
Methyl Ethyl Ketoxime (MEKO) helps to preserve the quality and usability of wood finishes, particularly in applications where extended storage times are common.
Methyl Ethyl Ketoxime (MEKO) is utilized in textile printing processes as an anti-skinning agent in printing pastes and inks. 

Methyl Ethyl Ketoxime (MEKO) helps to prevent drying and clogging of screens and rollers during the printing process, ensuring smooth and continuous operation in textile printing facilities.
Methyl Ethyl Ketoxime (MEKO) can be used in the production of plastics and resins as a stabilizer or inhibitor to prevent premature polymerization or degradation of the polymer matrix. 
Methyl Ethyl Ketoxime (MEKO) helps to maintain the integrity and performance of plastic materials during processing and storage.

Methyl Ethyl Ketoxime (MEKO) is incorporated into industrial cleaning formulations for the removal of coatings, adhesives, and sealants from equipment, machinery, and surfaces.
Its solvent properties facilitate the dissolution and removal of stubborn residues, making it effective in maintenance and repair operations.

Methyl Ethyl Ketoxime (MEKO) is sometimes used as a corrosion inhibitor in metalworking fluids, rust preventatives, and industrial coatings to protect metal surfaces from corrosion and oxidation. 
Methyl Ethyl Ketoxime (MEKO) forms a protective film on metal surfaces, preventing contact with moisture and corrosive agents.

Safety Profile Of Methyl Ethyl Ketoxime (MEKO):
Poison by intraperitoneal route. 
Moderately toxic by subcutaneous route. 
May explode if heated. 

Reacts with sulfuric acid to form an explosive product.
Methyl Ethyl Ketoxime (MEKO) can cause irritation to the skin upon direct contact, leading to redness, itching, or dermatitis. 
Prolonged or repeated exposure may exacerbate these effects. 

Methyl Ethyl Ketoxime (MEKO)'s important to wear appropriate protective clothing, such as gloves and long sleeves, when handling Methyl Ethyl Ketoxime (MEKO) to minimize skin contact.
Methyl Ethyl Ketoxime (MEKO vapor or liquid can irritate the eyes upon contact, causing redness, tearing, or discomfort. 
Eye protection, such as safety goggles or a face shield, should be worn when working with MEKO to prevent accidental splashes or exposure.

Inhalation of Methyl Ethyl Ketoxime (MEKO) vapor or mist can irritate the respiratory tract, leading to symptoms such as coughing, shortness of breath, or throat irritation.
Adequate ventilation should be maintained in work areas where Methyl Ethyl Ketoxime (MEKO) is used, and respiratory protection may be necessary in poorly ventilated spaces.
Some individuals may develop sensitization or allergic reactions to Methyl Ethyl Ketoxime (MEKO) upon repeated exposure. 

This can manifest as allergic dermatitis or respiratory sensitization, which may require medical attention and avoidance of further exposure.
While acute toxicity from Methyl Ethyl Ketoxime (MEKO) exposure is low, ingestion or inhalation of large amounts may cause more severe health effects, including headache, dizziness, nausea, or vomiting. 
Ingestion of Methyl Ethyl Ketoxime (MEKO) can also lead to gastrointestinal irritation or chemical burns in the mouth, throat, and stomach.