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METHYL SALICYLATE


EC / List no.: 204-317-7
CAS no.: 119-36-8
Mol. formula: C8H8O3


Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic compound with the formula C6H4(OH)(CO2CH3). 
Methyl Salicylate is the methyl ester of salicylic acid. Methyl Salicylate is a colorless, viscous liquid with a sweet, fruity odor reminiscent of root beer, but often associatively called "minty", as it is an ingredient in mint candies.
Methyl Salicylate is produced by many species of plants, particularly wintergreens. 
Methyl Salicylate is also produced synthetically, used as a fragrance and as a flavoring agent.

Biosynthesis and occurrence
Methyl salicylate was first isolated (from the plant Gaultheria procumbens) in 1843 by the French chemist Auguste André Thomas Cahours (1813–1891), who identified it as an ester of salicylic acid and methanol.

The biosynthesis of methyl salicylate arises via the hydroxylation of benzoic acid by a cytochrome P450 followed by methylation by a methylase enzyme.


Methyl salicylate as a plant metabolite

Wintergreen plants (Gaultheria procumbens)
Many plants produce methyl salicylate in small quantities. 
Methyl salicylate levels are often upregulated in response to biotic stress, especially infection by pathogens, where it plays a role in the induction of resistance.
 Methyl salicylate is believed to function by being metabolized to the plant hormone salicylic acid. 
Since methyl salicylate is volatile, these signals can spread through the air to distal parts of the same plant or even to neighboring plants, whereupon they can function as a mechanism of plant-plant communication, "warning" neighbors of danger.
Methyl salicylate is also released in some plants when they are damaged by herbivorous insects, where they may function as a cue aiding in the recruitment of predators.

Some plants produce methyl salicylate in larger quantities, where it likely involved in direct defense against predators or pathogens. 
Examples of this latter class include: some species of the genus Gaultheria in the family Ericaceae, including Gaultheria procumbens, the wintergreen or eastern teaberry; some species of the genus Betula in the family Betulaceae, particularly those in the subgenus Betulenta such as B. lenta, the black birch; all species of the genus Spiraea in the family Rosaceae, also called the meadowsweets; species of the genus Polygala in the family Polygalaceae. 
Methyl salicylate can also be a component of floral scents, especially in plants dependent on nocturnal pollinators like moths, scarab beetles, and (nocturnal) bees.


Commercial production
Methyl salicylate can be produced by esterifying salicylic acid with methanol.
Commercial methyl salicylate is now synthesized, but in the past, it was commonly distilled from the twigs of Betula lenta (sweet birch) and Gaultheria procumbens (eastern teaberry or wintergreen).


Uses
Methyl salicylate is used in high concentrations as a rubefacient and analgesic in deep heating liniments (such as Bengay) to treat joint and muscular pain. 
Randomised double blind trials report that evidence of its effectiveness is weak, but stronger for acute pain than chronic pain, and that effectiveness may be due entirely to counterirritation. However, in the body it metabolizes into salicylates, including salicylic acid, a known NSAID.

Methyl salicylate is used in low concentrations (0.04% and under) as a flavoring agent in chewing gum and mints. 
When mixed with sugar and dried, it is a potentially entertaining source of triboluminescence, for example by crushing Wint-O-Green Life Savers in a dark room. 
When crushed, sugar crystals emit light; methyl salicylate amplifies the spark because it fluoresces, absorbing ultraviolet light and re-emitting it in the visible spectrum.
Methyl Salicylate is used as an antiseptic in Listerine mouthwash produced by the Johnson & Johnson company.
Methyl Salicylate provides fragrance to various products and as an odor-masking agent for some organophosphate pesticides.

Methyl salicylate is also used as a bait for attracting male orchid bees for study, which apparently gather the chemical to synthesize pheromones, and to clear plant or animal tissue samples of color, and as such is useful for microscopy and immunohistochemistry when excess pigments obscure structures or block light in the tissue being examined. 
This clearing generally only takes a few minutes, but the tissue must first be dehydrated in alcohol.
Methyl Salicylate has also been discovered that methyl salicylate works as a kairomone that attracts some insects, such as the spotted lanternfly.

Additional applications include: used as a simulant or surrogate for the research of chemical warfare agent sulfur mustard, due to its similar chemical and physical properties. in restoring (at least temporarily) the elastomeric properties of old rubber rollers, especially in printers, and as a penetrating oil to loosen rusted parts.

Methyl salicylate is a benzoate ester that is the methyl ester of salicylic acid. 
Methyl Salicylate has a role as a flavouring agent, a metabolite and an insect attractant. 
Methyl Salicylate is a benzoate ester and a member of salicylates. 
Methyl Salicylate derives from a salicylic acid.

Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. 
The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. 
Methyl Salicylate can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. 
Methyl Salicylate forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen. 
For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments. 
Methyl Salicylate is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic in mouthwash solutions.

Use and Manufacturing
Household & Commercial/Institutional Products
• Auto Products
• Commercial / Institutional
• Home Maintenance
• Inside the Home
• Personal Care
• Pesticides
• Pet Care

Use Areas
• Agent for soaking up liquid
• Adhesion of molecules to a surface    
• Relating to agricultural, including the raising and farming of animals and growing of crops
• Related to animals (but non-veterinary) e.g., animal husbandry, farming of animals/animal production, raising of animals for food or fur, animal feed, products for household pets 
• Products used on crops, or related to the growing of crops    
• Air cleaners and anti-odor agents, air purifiers, air conditioners, air filters, general air care products
• Type of pesticide used to destroy or inhibit the growth of disease-causing mechanisms, can be impregnated into clothing
• Relatived to the maintenance and repair of automobiles, products for cleaning and caring for automobiles (auto shampoo, polish/wax, undercarriage treatment, brake grease) 
• Modifier used for chemical, when chemical is used in a laboratory    
• Agents of chemical warfare    
• Chemicals in cigarettes, or tobacco related products, or related to the manufacturing of tobacco products    
• Related to all forms of cleaning/washing, including cleaning products used in the home, laundry detergents, soaps, de-greasers, spot removers, etc
• General disinfectants/sanitizing agnets, disinfectants related to drugs
• Products used in an enclosed setting, such as boiler and tank cleansing agents, and drain cleaners
• Flooring materials (carpets, wood, vinyl flooring), or related to flooring such as wax or polish for floors
• Detergents with wide variety of applications
• Toilets, cleaning/sanitizing products for toilets    
• Term used for colorants, dyes, or pigments; includes colorants for drugs, textiles, personal care products (cosmetics, tatoo inks, hair dye), food colorants, and inks for printing
• General construction (as opposed to those things labeled
• Drug product, or related to the manufacturing of drugs; modified by veterinary, animal, or pet.
• Related to food production (restaurants, catering, etc)    
• Related to food and beverage service activities    
• Includes antifoaming agents, coagulating agents, dispersion agents, emulsifiers, flotation agents, foaming agents, viscosity adjustors, etc
• Shortening, cooking oils, vegetable and animal oils and fats    
• Includes spices, extracts, colorings, flavors, etc added to food for human consumption    
• General flavoring agents used in foods, including condiments and seasonings    
• Includes food packaging, paper plates, cutlery, small appliances such as roasters, etc.; does not include facilities that manufacture food
• Plastic products, industry for plastics, manufacturing of plastics, plastic additives
• Fragrances or odor agents, can be used in home products (cleaners, laundry products, air fresheners) or similar industrial products;
• Related to the activity of hunting    
• Generic lubricants, lubricants for engines, brake fluids, oils, etc
• Soaps, includes personal care products for cleansing the hands or body, and soaps/detergents for cleaning products, homes, etc
• Personal care products, including cosmetics, shampoos, perfumes, soaps, lotions, toothpastes, etc
• Fragrance used as a personal care product
• Consumer use first aid products
• Subcategory of personal care product, used to cleanse the mouth    
• Substances used for preventing, destroying or mitigating pests
• Type of pesticide
• Pesticide for non agricultural use    
• Includes preservatives used in cosmetics, film, wood preserving agents, foods, etc
• Includes spices, extracts, colorings, flavors, etc added to food for human consumption
• Car wax/polish, floor wax, general polishing agents, polish for metals, plastics, rubber, lacquers, leather, furniture, etc
• Relatived to the maintenance and repair of automobiles, products for cleaning and caring for automobiles (auto shampoo, polish/wax, undercarriage treatment, brake grease) 
• Related to fracking, natural gas, industrial gases    
• Paint removers, graffiti removers, or general solvents    
• Related to metals - manufacturing of metals, casting of metals, production of metals, surface treatment of metals, etc
• Includes water softeners, lime removers, and the products used in the process of the collection, purification, and distribution of water

Industry Uses
• Odor agents
• Plasticizers


Consumer Uses
• Air care products
• Cleaning and furnishing care products
• Laundry and dishwashing products
• Personal care products


General Manufacturing Information
Industry Processing Sectors
• All other chemical product and preparation manufacturing
• Food, beverage, and tobacco product manufacturing
• Fragrances
• Pesticide, fertilizer, and other agricultural chemical manufacturing
• Petroleum lubricating oil and grease manufacturing
• Plastic material and resin manufacturing
• Soap, cleaning compound, and toilet preparation manufacturing
• Wholesale and retail trade
    
Natural material is found in wintergreen oil, oil of wintergreen, birch oil, green tea seed oil, clove oil, Quercetin tree oil, tuberose oil, small when medicated oil, tea oil, ylang ylang oil and cherry, apple, strawberry fruit juice. 
Methyl Salicylate is a colorless or pale yellow, red or light yellow transparent oily liquid. 
A strong aroma of wintergreen oil. 
The relative molecular mass of 152.16. 
The relative density of 1.1738. 
Melting point-8.6 ℃. 
Boiling point 223.3 ℃. 
A flashpoint of 96 ℃. 
The refractive index of 1.5360. 
Methyl Salicylate is insoluble in water, soluble in alcohol, ether, acetic acid, and other common organic solvents. 
Methyl Salicylate is easy to change when exposed to air. 

Methyl salicylate can be used in the formulation of flavors, mainly for the deployment of ylang-ylang, tuberose, chypre, acacia, Fougere, orchids. 
But the most common use is perfuming toothpaste. 

Methyl salicylate is also used as preservatives, pesticides, polishes, inks, paints, polyester dye carriers in industrial fields

Applications
Methyl salicylate ointment is a common dermatology drug with analgesic, anti-inflammatory, bactericidal effect. 
Because it can induce local irritation, it is rarely orally used.
When spread in the skin,it is easily absorbed. 
Its liniments, ointments can be used for acute rheumatoid arthritis, low back pain and muscle pain, also itching and flavoring agents, flavoring agents, preservatives.

Appropriately use it as modifiers for some floral types , such as ylang ylang, magnolia, acacia, shy flower, tuberose, gardenia, bloom, sweet clover grass.
Methyl Salicylate is mainly used for medicine and hygiene products such as toothpaste, tooth powder, mouthwash, talcum powder, carminative oil. 
Methyl salicylate can also be used for industrial products such as glue, glue paper, card paste, paste. 
Methyl Salicylate can also be used for food flavor,such as strawberries, grapes, walnuts, spearmint, spicy flavor as a special green gas.
Methyl salicylate is used as high-temperature heat carrier in dyeing industry .
The product has similar-Pyrola odor ,when used as a spice, it is often used as flavoring agent for pharmaceutical drugs and the pigmentum.
Methyl Salicylate also has applications in blending spices, such as Quercetin trees in general flavors. 
Methyl salicylate is also used as solvents and intermediates for the manufacture of pesticides, fungicides, perfumes, paints, cosmetics, ink and dye fibers such help. 
Methyl salicylate reacts with ammonia to make salicylamide which is used for production of antipyretic analgesics salicylaldehyde ethyl amine ,and salicylamide itself is an anti-inflammatory drug. 
Methyl salicylate can be obtained by acetylation using acetylsalicylic acid methyl ester (C10H10O4, [580-02-9]). 
Add methyl salicylate and acetic anhydride into pot ,put sulfuric acid under stirring, the reaction temperature does not exceed 60 ℃ for about 1h, the reaction is completed, the reaction is poured into ice water and precipitated crystals are filtered, washed, dried, and acetylsalicylic acid methyl ester is obtained. 
Acetylsalicylic acid can be prepared by cyclization to get 4-hydroxy coumarin. 
Methyl salicylate is used as a pharmaceutical for external application agent.
Perfumes and suntan lotion ultraviolet absorber.


Production Method    
Methyl salicylate is widespread in nature, and it is a main ingredient of wintergreen, small medicated oil. 
Also it is present in essential oils of the tuberose, Quercetin tree, ylang ylang, cloves, tea. Salicylic acid and methanol are used to make it in the presence of sulfuric acid through esterification.
Salicylic acid is dissolved in methanol, add sulfuric acid, heat with stirring, the reaction time is 3h,90-100℃, cool to below 30 ℃,take oil ,wash with sodium carbonate solution to pH8 above, and then wash 1 time with water. 
Vacuum distillation, collect 95-110 ℃ (1.33-2.0kPa) distillate, obtain methyl salicylate. 
The yield is over 80%. 
General industrial methyl salicylate content is 99.5%. Material consumption fixed: Acid 950kg/t, methanol 400kg/t.


Description    
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester that is naturally produced by many species of plants. 
Some of the plants which produce it are called wintergreens, hence the common name. 
This compound is used as a fragrance. 
Methyl Salicylate is also found in liniments (rubbing ointments).


Chemical Properties    
Methyl Salicylate is the main component of wintergreen oil and occurs in small quantities in other essential oils and fruits. 
Methyl Salicylate is a colorless liquid with a sweet, phenolic odor.
Methyl salicylate has a characteristic wintergreen-like odor. 
May be prepared by extraction from natural sources; or by esterification of salicylic acid with methanol.
Wintergreen is an evergreen shrub with slender, creeping stems, assurgent, flowering branches with toothed leaves clustered at the top, white, bell-shaped flowers blossoming July to August, followed by red berries (checkerberries). 
The plant grows extensively in the woods of Canada and the United States (Pennsylvania). 
The leaves are harvested between June and September. 
Wintergreen has an aromatic odor and flavor similar to methyl salicylate.

Occurrence    
Numerous plants produce methyl salicylate in very small amounts. Some plants, such as the following, produce more:
Some species of the genus Gaultheria in the family Ericaceae, including Gaultheria procumbens, the wintergreen or eastern teaberry;
Some species of the genus Betula in the family Betulaceae, particularly those in the subgenus Betulenta such as B. lenta, the black birch;
All species of the genus Spiraea in the family Rosaceae, also called the meadowsweets.
This compound is produced most likely as an anti-herbivore defense. 
If the plant is infected with herbivorous insects, the release of methyl salicylate may function as an aid in the recruitment of beneficial insects to kill the herbivorous insects.
A side from its toxicity, methyl salicylate may also be used by plants as a pheromone to warn other plants of pathogens such as tobacco mosaic virus.

Uses
Methyl salicylate occurs in the leaves ofGaultheria procumbens L. and in the barkof Betulaceae. 
Methyl Salicylate is produced by esterificationof salicylic acid with methanol. Methyl Salicylate is used inperfumery and as a flavoring agent.
In high concentrations as a rubefacient in deep heating liniments (such as Bengay) to treat joint and muscular pain. 
Randomised double blind trial reviews report evidence of its effectiveness that is weak, but stronger for acute pain than chronic pain, and that effectiveness may be due entirely to counter-irritation. 
However, in the body it metabolizes into salicylates, including salicylic acid, a known NSAID.
In low concentrations as a flavoring agent (no more than 0.04%; it is toxic).
providing fragrance to various products and as an odor-masking agent for some organophosphate pesticides. 
If used excessively, it can cause stomach and kidney problems.
Attracting male orchid bees, who apparently gather the chemical to synthesize pheromones; it is commonly used as bait to attract and collect these bees for study.
Clear plant or animal tissue samples of color, and as such is useful for microscopy and immunohistochemistry when excess pigments obscure structures or block light in the tissue being examined. 
This clearing generally only takes a few minutes, but the tissue must first be dehydrated in alcohol.
A mint flavoring in some kinds of chewing gum and candy, as an alternative to the more common peppermint and spearmint oils. 
Methyl Salicylate can also be found as a flavoring of root beer. 
Methyl Salicylate is also a potentially entertaining source of tri boluminescence ; when mixed with sugar and dried, it gains the tendency to build up electrical charge when crushed or rubbed. 
This effect can be observed by crushing wintergreen Life Savers candy in a dark room.

Methyl salicylate is an organic ester that is commonly produced naturally by wintergreens. 
Methyl salicylate is utilize as a anti-herbivore defense system in various plants that produces it. 
Methyl salicylate is also used in high concentrations as a rubefacient to treat joint, muscular pain and acute pain.
Methyl salicylate is also used as a flavoring agent and often used to provide fragrance to pr oducts.

Potent inhibitor of ornithine decarboxylase

Preparation    
Methyl salicylate can be produced by esterifying salicylic acid with methanol. Commercial methyl salicylate is now synthesized, but in the past, it was commonly distilled from the twigs of Betula lenta (sweet birch) and Gaultheria procumbens (eastern teaberry or winter green).


Production Methods    
Methyl acetate, a novel acyl acceptor for biodiesel production has been developed, and a comparative study on Novozym 435-catalyzed transesterification of soybean oil for biodiesel production with different acyl acceptors has been studied (Noureddini et al., 2005).

Methyl salicylate is used in the following products: washing & cleaning products, air care products, biocides (e.g. disinfectants, pest control products), polishes and waxes, cosmetics and personal care products and perfumes and fragrances. Other release to the environment of Methyl salicylate is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

Methyl salicylate is used in the following products: washing & cleaning products, cosmetics and personal care products, polishes and waxes, fuels, air care products, biocides (e.g. disinfectants, pest control products), laboratory chemicals, perfumes and fragrances and pharmaceuticals.
Methyl salicylate is used in the following areas: health services.
Other release to the environment of Methyl salicylate is likely to occur from: indoor use as processing aid, outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Methyl salicylate is used in the following products: perfumes and fragrances, cosmetics and personal care products, air care products, washing & cleaning products and fuels.
Release to the environment of Methyl salicylate can occur from industrial use: formulation of mixtures.

Methyl salicylate is used in the following products: washing & cleaning products, cosmetics and personal care products, fuels, laboratory chemicals, perfumes and fragrances, pharmaceuticals, air care products, biocides (e.g. disinfectants, pest control products) and polishes and waxes.
Methyl salicylate is used in the following areas: scientific research and development and health services.
Methyl salicylate is used for the manufacture of: chemicals and food products.
Release to the environment of Methyl salicylate can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), in the production of articles and of substances in closed systems with minimal release.

What is methyl salicylate?
Methyl salicylate is an external analgesic available in over-the-counter (OTC) medicines that temporarily relieve minor body aches and muscle and joint pain associated with backache, arthritis, strains, sprains, and bruises. Methyl salicylate can be found in topical pain medicines (e.g., creams or ointments) that contain more than one external analgesic active ingredient.

What is methyl salicylate used to treat?
Relieves minor body aches
Relieves muscle and joint pain

Methyl salicylate is a topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.


Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. 
The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. 
It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. 
It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen. For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments. 
It is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic in mouthwash solutions.

Pharmacodynamics
Methyl salicylate relieves musculoskeletal pain in the muscles, joints, and tendons by causing irritation and reddening of the skin due to dilated capillaries and increased blood flow. 
It is pharmacologically similar to aspirin and other NSAIDs but as a topical agent, it primarily acts as a rubefacient and skin irritant. 
Counter-irritation is believed to cause a soothing sensation of warmth.

Mechanism of action
Counter-irritation is thought to be effective at alleviating musculoskeletal pain as the irritation of the sensory nerve endings is thought to alter or offset the pain in the underlying muscle or joints that are served by the same nerves 5. 
This is thought to mask the underlying musculoskeletal pain and discomfort. 
When applied topically, methyl salicylate is thought to penetrate the skin and underlying tissues where it reversibly inhibits cyclooxygenase enzyme and locally and peripherally prevents the production of inflammatory mediators such as prostaglandin and thromboxane A2.

Absorption
Approximately 12-20% of topically applied methyl salicylate may be systemically absorbed through intact skin within 10 hours of application, and absorption varies with different conditions such as surface area and pH. 
Dermal bioavailability is in the range of 11.8 – 30.7%. 
For the assessment of potential oral exposure to salicylates, bioavailability is assumed to be 100% 9.

Volume of distribution
After absorption, methyl salicylate is distributed throughout most body tissues and most transcellular fluids, primarily by pH-dependent passive processes. 
Salicylate is actively transported by a low-capacity, saturable system out of the CSF across the choroid plexus. 
The drug readily crosses the placental barrier.

Protein binding
The degree of albumin binding depends on the plasma concentration of the compound

Metabolism
Minor metabolism may occur in various tissues but hepatic metabolism constitutes the majority of metabolic processes of absorbed methyl salicylate. 
It is mainly hydrolyzed to salicylic acid via hepatic esterase enzymes. 
Conjugation with glycine forms salicyluric acid and conjugation with glucuronic forms ester or acyl and ether or phenolic glucuronide, which are the three main metabolites.

Uses
This product is used to treat minor aches and pains of the muscles/joints (such as arthritis, backache, sprains). 
Menthol and methyl salicylate work by causing the skin to feel cool and then warm. 
These feelings on the skin distract you from feeling the aches/pains deeper in your muscles and joints.

IUPAC names
- methyl 2-hydroxybenzoate
METHYL 2-HYDROXYBENZOATE
Methyl 2-hydroxybenzoate
methyl 2-hydroxybenzoate
methyl 2-hydroxybenzoic acid
METHYL SALICYLATE
Methyl Salicylate
Methyl salicylate
methyl salicylate
Methyl Salicylate
Methyl salicylate
methyl salicylate
methyl-2-hydroxybenzoate
METHYL-SALICYLATE
Metil szalicilát
salicylic acid, methyl ester
Wintergreen
Wintergreen Essential Oil
Wintergreen oil
Wintergreen Oil (procumbens)

SYNONYMS:
Birch-Me, AR,99%
Methyl salicylate In stock Factory
Methyl salicylate/2-hydroxy-benzoicacimethylester
WINTERGREEN
WINTERGREEN OIL, SYNTHETIC
SYNTHETIC OIL OF WINTERGREEN
SWEET BIRCH OIL
RARECHEM AL BF 0029
o-Hydroxybenzoic acid methyl ester
OIL OF WINTERGREEN
2-HYDROXYBENZOIC ACID METHYL ESTER
2-(methoxycarbonyl)phenol
2-Carbomethoxyphenol
FEMA 2745
FEMA 2154
exagien
Flucarmit
Gaultheria oil
BETULA OIL
BIRCH OIL, SWEET
Linsal
METHYL 2-HYDROXYBENZOATE
METHYL HYDROXYBENZOATE
METHYLIS SALICYLAS
METHYL SALICYLATE
METHYL-O-HYDROXYBENZOATE
Methyl Salicylate 2-Hydroxybenzoic acid methyl ester Wintergreen oil
METHYL SALICYLATE NF FCC
METHYL SALICYLATE EXTRA PURE, DAB, PH. E UR., B. P., PH. FRANC.
METHYL SALICYLATE BP/USP GRADE
THYL SALICYLATE
2-Hydroxybenzoic acid methyl
Methyl salicylate,98%
Methyl salicylate,2-Hydroxybenzoic acid methyl ester, Methyl 2-hydroxybenzoate, Oil of wintergreen, Wintergreen oil
Methyl salicylate,2-Hydroxybenzoic acid methyl ester, Methyl 2-hydroxybenzoate, Methylis salicylas, Oil of wintergreen, Wintergreen oil
Methyl salicylate, extra pure
Methyl Salicylate (2 mL) (AS)
Methyl Salicylate (AS)
Methyl Liu
Anthrapole ND
NSC 8204
Methyl salicylate, 99% 5ML
benzoic acid, 2-hydroxy-, methyl ester (9ci)
Hyl Salicylate
2-Hydroxybenzoic Acid Methyl Ester Salicylic Acid Methyl Ester Methyl 2-Hydroxybenzoate
PredaLure
Methyl salicyl
Methyl salicylate 2-Carbomethoxyphenol
Methyl salicylate Vetec(TM) reagent grade, 99%
Methyl Salicylate (2 mL)
METHYL SALICYLATE BIOXTRA
2-Hydroxybenzoic acid methyl ester Methyl 2-hydroxybenzoate Oil of wintergreen Wintergreen oil Methyl hydroxybenzoate Salicylic Acid Methyl Ester
2-hydroxy-benzoicacimethylester
Benzoic acid, 2-hydroxy-, methyl ester
Benzoicacid,2-hydroxy-,methylester
Betula
Betula Lenta

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