PRODUCTS

METHYLISOTHIAZOLINONE

CAS NUMBER: 2682-20-4

EC NUMBER: 220-239-6

MOLECULAR FORMULA: C4H5NOS

MOLECULAR WEIGHT: 115.16

IUPAC NAME: 2-methyl-1,2-thiazol-3-one

Methylisothiazolinone is a 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom.
Methylisothiazolinone is a powerful biocide and preservative and is the minor active ingredient in the commercial product Kathon(TM).
Methylisothiazolinone has a role as an antifouling biocide, an antimicrobial agent and an antifungal agent.

Methylisothiazolinone is the organic compound with the formula S(CH)2C(O)NCH3.
Methylisothiazolinone is a white solid.

Methylisothiazolinone, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications.
Methylisothiazolinone and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis

Methylisothiazolinone is used for controlling microbial growth in water-containing solutions.
Methylisothiazolinone is typically used in a formulation with 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT), in a 3:1 mixture (CMIT:MIT) sold commercially as Kathon.

Methylisothiazolinone is supplied to manufacturers as a concentrated stock solution containing from 1.5–15% of CMIT/MIT.
Methylisothiazolinone also has been used to control slime in the manufacture of paper products that contact food.
In addition, Methylisothiazolinone serves as an antimicrobial agent in latex adhesives and in paper coatings that also contact food

Methylisothiazolinone is a preservative that is found in a wide array of liquid cosmetics, personal care products and cleaning products on the market today.
Methylisothiazolinone's function is to inhibit the growth of bacteria.

What products is Methylisothiazolinone in?
Methylisothiazolinone is found in a multitude of products, including those claiming to be “natural”.
The list includes cleaning products, detergents, lotions, sunscreens, shampoos, conditioners, hair coloring, body washes, mascara, shaving cream, make-up remover, liquid soaps, and baby products including wipes, lotions and shampoos.

Methylisothiazolinone is widely used preservatives found in liquid cosmetic and personal care products.
Both chemicals inhibit bacterial growth in cosmetic products on their own, but they are most commonly used as a mixture in products

USAGE:

-Shampoo
-Conditioner
-Hair color
-Body wash
-Lotion
-Sunscreen
-Mascara
-Shaving cream
-Baby lotion
-Baby shampoo
-Hairspray
-Makeup remover
-Liquid soaps and detergents.

Methylisothiazolinone is a preservative that’s active against bacteria, yeast, and fungi.
Methylisothiazolinone’s used in the manufacture of water-based cosmetics and personal care products.

Methylisothiazolinone’s also used in industrial processes, including the manufacture of:
-paper coatings
-detergents
-paints
-glue
-cutting oils

Methylisothiazolinone is a preservative used in personal hygiene products (such as shampoos, lotions, emulsions, and sun screens), and in industrial cooling oils, cutting oils, and paper finishes.
Methylisothiazolinone is also commonly added to household cleaners as a substitute for formaldehyde.

Methylisothiazolinone is a clear, colourless liquid that is soluble in water.
Methylisothiazolinone enhances the safety and shelf-life of products by preventing the growth of bacteria and yeasts.
Without preservatives like Methylisothiazolinone, products could start to smell unpleasant, change colour or grow moulds which can produce toxins which are harmful to health.

Methylisothiazolinone is a biocide and is used to control microbial growth in water containing solutions
Methylisothiazolinone has antibacterial and antifungal properties, giving it broadly the same uses as MI

PHYSICAL PROPERTIES:

-Molecular Weight: 115.16

-XLogP3-AA: 0

-Exact Mass: 115.00918496

-Monoisotopic Mass: 115.00918496

-Topological Polar Surface Area: 45.6 Å²

-Physical Description: Dark yellow powder with lumps

-Color: Colorless

-Form: Prisms

-Boiling Point: 93 °C

-Melting Point: 50-51 °C

-Density: 1.35 g/mL

-Vapor Pressure: 0.062 mmHg

-Chemical Classes: Other Uses -> Biocides/Disinfectants

Methylisothiazolinone is a isothiazolinone based biocide and preservative used in personal care products.
Methylisothiazolinone is also used for controlling microbial growth in water-c ontaining solution.

Methylisothiazolinone is a powerful synthetic biocide and preservative within the group of isothiazolinones.
Methylisothiazolinone is used to control slime-forming bacteria, fungi, and algae in pulp/paper mills, cooling water systems, oil field operations, industrial process waters, and air washer systems.

CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 0

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 0

-Heavy Atom Count: 7

-Formal Charge: 0

-Complexity: 121

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

And Methylisothiazolinone is incorporated into adhesives, coatings, fuels, metal working fluids, resin emulsions, paints, and various other specialty industrial products as a preservative.
Methylisothiazolinone is also used to control the growth of mold, mildew, and sapstain on wood products.

Methylisothiazolinone is generally recommended for use only in rinse-off and leave-on cosmetic products (maximum concentration of 100 ppm) as preservative such as shampoo, conditioner, hair color, body wash, lotion, sunscreen, mascara, shaving cream, baby lotion, baby shampoo, hairspray, makeup remover, liquid soaps, and detergents.
Methylisothiazolinone is reported that methylisothiazolinone in rinse-off products causes allergic contact dermatitis.
Methylisothiazolinone as it is sometimes known, is a preservative used in cosmetics and beauty products.

Methylisothiazolinone is a powerful biocide, or “chemical substance capable of killing living organisms, usually in a selective way.”
Ultimately, Methylisothiazolinone is used to prevent a wide variety of bacteria and fungi from growing in cosmetics and beauty products, most often in shampoo.
Methylisothiazolinone is only approved for use in rinse-off formulas and at low concentrations.

Methylisothiazolinone is a preservative in many skin care products that stops fungi, yeast, and bacteria from growing
Methylisothiazolinone is a synthetic ingredient that is commonly found in many household cleaners

Methylisothiazolinone is a synthetic chemical used in consumer products for its antimicrobial properties.
Methylisothiazolinone is most often applied to cleaning products as a synthetic preservative.
Methylisothiazolinone is used to extend a product’s shelf life and protect consumers against exposure to bacteria and mold by inhibiting the growth of those organisms.

Methylisothiazolinone is a powerful biocide and preservative and is the minor active ingredient in the commercial product Kathon(TM).
Methylisothiazolinone has a role as an antifouling biocide, an antimicrobial agent and an antifungal agent.

Methylisothiazolinone is a white solid.
Methylisothiazolinone is used for controlling microbial growth in water-containing solutions.

Methylisothiazolinone is a preservative that is found in personal care products and cleaning products
Methylisothiazolinone is widely used preservatives found in liquid cosmetic and personal care products.

Methylisothiazolinone’s used in the manufacture of water-based cosmetics and personal care products.
Methylisothiazolinone is also commonly added to household cleaners as a substitute for formaldehyde.
Methylisothiazolinone is a clear, colourless liquid that is soluble in water.

SYNONYMS:

2-Methyl-4-isothiazolin-3-one
2682-20-4
Methylisothiazolinone
2-methylisothiazol-3(2h)-one
2-Methyl-3(2H)-isothiazolone
2-Methyl-4-isothiazoline-3-one
3(2H)-Isothiazolone, 2-methyl-
2-methyl-1,2-thiazol-3-one
N-Methyl-3-oxodihydroisothiazole
2-methyl-3-isothiazolone
2-methyl-1,2-thiazol-3(2H)-one
N-METHYL-3-OXODIHYDRO ISOTHIAZOLE
n-methylisothiazolin-3-one
2-METHYL-2H-ISOTHIAZOL-3-ONE
Microcare MT
Kordek MLX
EINECS 220-239-6
MIT (biocide)
Acticide M 10
Acticide M 20
Bestcide 600
Kordek 50
Kordek 50C
Kordek 573F
Kathon CG 243
2-Methyl-4-isothiazoline-3-ketone
2-Methyl-4-isothiazolin-3-one (MI)
2-methyl-4-isothiazolinone
Methylisothiazolinone free base
2-Methyl 4-Isothiazoline 3-one
METHYLISOTHIAZOLINONE [II]
METHYLISOTHIAZOLINONE
2-Methyl-3(2H)-isothiazolone #
METHYLISOTHIAZOLINONE
METHYLISOTHIAZOLINONE
2-Methyl-4-isothiazolin-3-one, 95%
CAS-2682-20-4
2-methyl-2,3-dihydro-1,2-thiazol-3-one
2-Methyl-4-isothiazolin-3-one, analytical standard
W-107150
2-Methyl-4-isothiazolin-3-one, 50% aqueous solution
Z3227502095
2-Methyl-4-isothiazolin-3-one 100 microg/mL in Acetonitrile
1-(4-CHLOROPHENYL)-3-(3,4-DICHLOROPHENYL)UREA
2-METHYL-3(2H)-ISOTHIAZOLONE
2-METHYL-4-ISOTHIAZOLIN-3-ONE
2-METHYL-4-ISOTHIAZOLINE-3-ONE
3,4,4 TRICHLOROCARBANILIDE
3,4,4'-TRICHLOROCARBANILIDE
3,4,4'-TRICHLORODIPHENYLUREA
CUTISAN
N-(3,4-DICHLOROPHENYL)-N'-(4-CHLOROPHENYL)UREA
N-(4-CHLOROPHENYL)-N-(3,4-DICHLOROPHENYL)-UREA
N-METHYL-3-OXODIHYDRO ISOTHIAZOLE
TCC
TRICHLOROCARBANILIDE
TRICLOCARBAN
2-methyl-3(2h)-isothiazolon
Isothiazolone,2-methyl-
Methylisothiazolinone
Skycide 100
2-methyl-2H-isothiazol-3-one
2-Methylisothiazolin-3-one
2-Methyl-1,2-thiazol-3(2H)-on
2-Methyl-1,2-thiazol-3(2H)-one
2-Méthyl-1,2-thiazol-3(2H)-one
2-methyl-4-isothiazolin-3-one
2-Methyl-4-isothiazoline-3-one
2-Methylisothiazol-3(2H)-one
3(2H)-Isothiazolone, 2-methyl-
606203
methylisothiazolinone
MI
MIT
N-Methylisothiazolone
NX8157080
2682-20-4 (free base)
2-Methyl 4-Isothiazoline 3-one
2-methyl-1,2-thiazol-3-one
2-methyl-2,3-dihydro-1,2-thiazol-3-one
2-Methyl-2H-isothiazol-3-one
2-methyl-3-isothiazolidinone
2-methyl-3-isothiazolone
2-Methyl-4-isothiazolin-3-one (MI)
2-methyl-4-isothiazolin-3-one(mit)
2-methylisothiazol-3-one
3(2H)-ISOTHIAZOLONE, METHYL-
4670-10-4
Methylisothiazolinone|2-methyl-3(2H)-isothiazolone
NCGC00164391-01
N-Methyl-3-oxodihydroisothiazole