Methylparaben is a widely used preservative belonging to the paraben family, commonly used to prevent microbial growth and extend the shelf life of products.
Derived from para-hydroxybenzoic acid, Methylparaben is recognized for its antimicrobial properties and compatibility with a variety of formulations.
Methylparaben is extensively utilized in cosmetics, personal care, pharmaceuticals, and food products due to its effectiveness and safety at low concentrations.
CAS Number: 99-76-3
EC Number: 202-785-7
Molecular Formula: C8H8O3
Molecular Weight: 152.15 g/mol
Synonyms: Methylparaben, Methyl Parahydroxybenzoate, Methyl p-Hydroxybenzoate, Nipagin M, Preservative Methylparaben, Methyl Ester of p-Hydroxybenzoic Acid, Paraben M, Cosmetic Grade Methylparaben, Pharmaceutical Grade Methylparaben, Food Grade Methylparaben, E218 (Food Additive Code), Methyl Hydroxybenzoate, Paraben Preservative, Antimicrobial Methylparaben, Methylparaben Preservative for Cosmetics
APPLICATIONS
Methylparaben is extensively used in skincare products, such as creams and lotions, to prevent microbial contamination and ensure product stability.
Methylparaben is included in hair care formulations, such as shampoos and conditioners, to maintain freshness and prolong shelf life.
Methylparaben is employed in color cosmetics, including foundations and mascaras, to prevent bacterial and fungal growth.
Methylparaben is added to sunscreens to inhibit microbial proliferation and extend product durability.
Methylparaben is utilized in personal hygiene products, such as deodorants and body washes, for its preservative properties.
Methylparaben is found in pharmaceutical formulations, including ointments and eye drops, to ensure sterility and safety.
Methylparaben is incorporated into food products, such as baked goods and sauces, as an antimicrobial agent under the food additive code E218.
Methylparaben is applied in beverage preservation to prevent spoilage caused by molds and yeasts.
Methylparaben is included in pet care products, such as shampoos and conditioners, to ensure product safety and longevity.
Methylparaben is used in dental care products, such as toothpaste and mouthwash, to inhibit microbial growth and enhance shelf life.
Methylparaben is incorporated into baby care formulations, such as lotions and powders, due to its mildness and safety profile.
Methylparaben is added to medical-grade products, such as wound care solutions, to maintain sterility during storage.
Methylparaben is employed in industrial applications, such as lubricants and adhesives, to prevent microbial degradation.
Methylparaben is found in specialty products for sensitive skin, ensuring safe preservation without compromising mildness.
Methylparaben is applied in natural and organic formulations at low concentrations to meet safety standards while retaining product integrity.
Methylparaben is included in specialty coatings and films for its antimicrobial and preservative properties.
Methylparaben is used in laboratory settings to stabilize samples and reagents for extended analysis periods.
Methylparaben is applied in pharmaceutical syrups and liquid medications to prevent spoilage and extend usability.
Methylparaben is widely used in cosmetics and personal care products as a preservative to prevent the growth of bacteria, fungi, and mold.
Methylparaben is included in skin care products such as moisturizers and cleansers to extend shelf life and maintain product safety.
Methylparaben is employed in shampoos and conditioners to prevent microbial contamination and enhance the stability of the formulation.
Methylparaben is used in body lotions and creams for its preservative properties, helping to protect the product from spoilage.
Methylparaben is applied in hair care products like hair dyes and treatments to maintain product integrity and ensure it remains safe for use over time.
Methylparaben is incorporated into deodorants to prevent the growth of harmful microorganisms and ensure the product stays fresh.
Methylparaben is used in sunscreens to protect the product from microbial contamination and maintain its effectiveness during storage.
Methylparaben is employed in facial masks and serums to improve the shelf life of active ingredients and maintain product safety.
Methylparaben is used in baby care products for its antimicrobial properties, ensuring the product remains safe for young skin.
Methylparaben is included in makeup products such as foundations, mascaras, and powders to help preserve the product and prevent contamination.
Methylparaben is used in facial cleansers to keep the formulation free from bacterial growth and maintain product stability.
Methylparaben is applied in foot care products to extend shelf life while preventing bacterial and fungal contamination.
Methylparaben is used in anti-aging products to ensure the stability of the ingredients and maintain their effectiveness.
Methylparaben is incorporated in acne treatments to preserve the formula and prevent the growth of bacteria that could worsen skin conditions.
Methylparaben is employed in personal care wipes to maintain hygiene and protect against microbial contamination.
Methylparaben is used in body sprays and perfumes to preserve the fragrance and ensure its long-lasting appeal.
Methylparaben is included in medical and pharmaceutical formulations to maintain product safety and prevent bacterial growth.
Methylparaben is applied in wound care products to ensure the formula remains safe for use and resistant to microbial contamination.
Methylparaben is used in oral care products like toothpaste and mouthwashes to prevent microbial growth and ensure hygiene.
Methylparaben is incorporated in air fresheners to prevent microbial growth while providing long-lasting fragrance.
Methylparaben is employed in lotions for dry skin to help maintain the formulation’s stability and prevent spoilage.
Methylparaben is used in dental products to maintain the integrity of the formula and protect it from bacterial contamination.
Methylparaben is used in insect repellents to maintain the stability of active ingredients and extend shelf life.
Methylparaben is employed in anti-cellulite treatments to ensure the formulation remains safe and effective for its intended use.
Methylparaben is used in bath and shower gels to preserve the formula and maintain the safety of the product.
DESCRIPTION
Methylparaben is a white crystalline powder or colorless crystalline solid with a faint characteristic odor.
This compound is highly soluble in alcohol and slightly soluble in water, facilitating its incorporation into various formulations.
Methylparaben exhibits broad-spectrum antimicrobial activity against bacteria, yeasts, and molds, making it highly effective as a preservative.
Methylparaben is stable across a wide pH range (4–8), ensuring compatibility with diverse cosmetic and pharmaceutical products.
This preservative is used at low concentrations, typically between 0.1% and 0.5%, ensuring efficacy without compromising safety.
Methylparaben is biodegradable and environmentally friendly, breaking down into harmless byproducts in natural settings.
Methylparaben is recognized for its low toxicity and high safety profile, making it suitable for use in personal care and food applications.
This compound enhances the shelf life and stability of formulations, reducing the need for additional preservatives.
Methylparaben’s antimicrobial properties make it ideal for preventing contamination in multi-use and long-term storage products.
Methylparaben is a widely used preservative in cosmetics and personal care products, known for its ability to prevent microbial growth and extend shelf life.
Methylparaben is a colorless, odorless compound that is soluble in alcohol and water, making it suitable for incorporation into a wide range of formulations.
Methylparaben is part of the parabens family, which includes other common preservatives such as ethylparaben, butylparaben, and propylparaben.
Methylparaben is effective against bacteria, fungi, and mold, ensuring that personal care products remain safe for use over time.
Methylparaben is commonly used in low concentrations (0.1% to 0.3%) in cosmetic formulations to achieve optimal preservative efficacy without affecting product quality.
Methylparaben has a low toxicity profile when used at recommended levels, making it one of the most popular preservatives in the cosmetics industry.
Methylparaben is often combined with other preservatives to achieve a broad spectrum of antimicrobial protection and to enhance product stability.
Methylparaben is widely accepted by regulatory bodies, including the FDA and the European Commission, as a safe and effective preservative when used within recommended concentrations.
Methylparaben is sometimes included in products designed for sensitive skin, as it helps to keep the formulation safe from contamination while maintaining product effectiveness.
Methylparaben has antioxidant properties that can also help protect cosmetic formulations from oxidative damage, further enhancing the stability of the product.
PROPERTIES
Chemical Formula: C8H8O3
Molecular Weight: 152.15 g/mol
Common Name: Methylparaben
Appearance: White crystalline powder or colorless crystals
Odor: Faint, characteristic odor
Density: Approx. 1.46 g/cm³
Melting Point: 125–128°C
Solubility: Soluble in alcohol, slightly soluble in water
Reactivity: Stable under normal conditions; avoid strong oxidizing agents
Chemical Stability: Stable across pH 4–8
Storage Temperature: Store at 15–25°C in a cool, dry place
FIRST AID
Inhalation:
If Methylparaben dust is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.
Skin Contact:
Wash the affected area thoroughly with soap and water.
If skin irritation or rash develops, seek medical attention.
Remove contaminated clothing and wash before reuse.
Eye Contact:
Flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.
Ingestion:
If Methylparaben is ingested, rinse the mouth thoroughly with water.
Do not induce vomiting unless instructed by medical personnel.
Seek immediate medical attention if discomfort persists.
If the person is conscious, give small sips of water to drink.
Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.
HANDLING AND STORAGE
Handling:
Personal Protection:
Wear appropriate personal protective equipment (PPE), such as gloves, safety goggles, and protective clothing, when handling Methylparaben.
Use in a well-ventilated area to minimize exposure to dust.
Ventilation:
Ensure proper ventilation during handling to prevent airborne particle accumulation.
Use local exhaust systems if necessary.
Avoidance:
Avoid direct contact with eyes, skin, and clothing.
Do not eat, drink, or smoke while handling.
Wash hands thoroughly after handling.
Spill and Leak Procedures:
Contain spills to prevent further release.
Use inert absorbent materials (e.g., sand, vermiculite) to collect spilled material.
Dispose of waste according to local regulations.
Storage:
Store in a cool, dry, well-ventilated area away from heat and incompatible materials.
Keep containers tightly closed and protected from sunlight.
Avoid freezing or excessive heat to maintain stability.
Handling Cautions:
Ensure storage containers are compatible and sealed properly.
Avoid contamination during handling to preserve product integrity.