Monobasic sodium phosphate monohydrate is also used in water treatment processes to adjust the pH of water, ensuring it meets the required standards for use in various applications.
Monobasic sodium phosphate monohydrates ability to function as a stabilizer, buffer, and pH regulator makes it an important compound in scientific and industrial fields.
Monobasic sodium phosphate monohydrate is an important compound with diverse uses across multiple industries, primarily due to its ability to regulate pH and act as a buffering agent.
CAS Number: 14265-44-2
Molecular Formula: O4P-3
Molecular Weight: 94.97
EINECS Number: 604-302-9
Synonyms: 10049-21-5, Sodium phosphate monobasic monohydrate, Sodium dihydrogen phosphate monohydrate, Monosodium phosphate monohydrate, MFCD00149208, Phosphoric acid, monosodium salt, monohydrate, sodium;dihydrogen phosphate;hydrate, Sodium Phosphate Monobasic hydrate, sodium dihydrogenphosphate monohydrate, SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE, 593YOG76RN, Phosphoric acid, monosodium salt, monohydrate (8CI,9CI), Phosphoric acid (sodium hydrate), UNII-593YOG76RN, MSP Monohydrate, sodium dihydrogen phosphate hydrate, SodiumPhosphateMonobasichydrate, DTXSID6073994, sodium dihydrogenphosphate hydrate, CHEBI:114249, monohydratemonobasicsodium phosphate, sodium dihydrogen phosphate, hydrate, sodium hydrate dihydrogenphosphate ion, AKOS015913977, AKOS028109193, sodium phosphate mono-basic monohydrate, monosodium mono(hydrogenphosphate) hydrate, sodium dihydrogen phosphate--water (1/1), MONOBASIC SODIUM PHOSPHATE MONOHYDRATE, NS00134324, Sodium phosphate monobasic monohydrate, p.a., MONOBASIC SODIUM PHOSPHATE, MONOHYDRATE, SODIUM PHOSPHATE MONOBASIC, MONOHYDRATE, SODIUM PHOSPHATE MONOBASIC (MONOHYDRATE), Sodium phosphate monobasic monohydrate ACS granular, Sodium dihydrogen phosphate monohydrate, Puratronic?, SODIUM PHOSPHATE, MONOBASIC MONOHYDRATE [MI], Q27195646, SODIUM PHOSPHATE MONOBASIC,MONOHYDRATE [VANDF], SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE [II], SODIUM PHOSPHATE,MONOBASIC,MONOHYDRATE [VANDF], SODIUM PHOSPHATE MONOBASIC (MONOHYDRATE) [WHO-DD], Sodium phosphate monobasic monohydrate, ACS reagent, >=98%, Sodium phosphate monobasic monohydrate, technical grade, 90%, SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE [ORANGE BOOK], Sodium Phosphate, Monobasic, Monohydrate, Cell Culture Grade, OSMOPREP COMPONENT SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE, Sodium phosphate monobasic monohydrate, purum p.a., >=99.0% (T), VISICOL COMPONENT SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE, Sodium phosphate monobasic monohydrate, Vetec(TM) reagent grade, 98%, Sodium phosphate monobasic monohydrate, BioXtra, for molecular biology, >=99.5% (T), Sodium phosphate monobasic monohydrate, puriss. p.a., ACS reagent, >=99.0% (T), Sodium phosphate monobasic monohydrate, BioReagent, suitable for electrophoresis, 98.0-102.0%, BETZ 0264;BUFFER SODIUM PHOSPHATE;DIHYDROGEN SODIUM PHOSPHATE MONOHYDRATE;SODIUM PHOSPHATE, MONOBASIC, HYDRATE;SODIUM PHOSPHATE MONOBASIC: MONOHYDRATE;SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE;SODIUM PHOSPHATE MONOHYDRATE;SODIUM ACID PHOSPHATE
Monobasic sodium phosphate monohydrate, is an inorganic compound.
Monobasic sodium phosphate monohydrate is a sodium salt of phosphoric acid.
Monobasic sodium phosphate monohydrate consists of sodium cations (Na+) and dihydrogen phosphate anions (H2PO−4).
One of many sodium phosphates, Monobasic sodium phosphate monohydrate is a common industrial chemical.
The salt exists in an anhydrous form, as well as monohydrate and dihydrate (NaH2PO4·H2O and NaH2PO4·2H2O respectively).
Monobasic sodium phosphate monohydrate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement.
A phosphate ion that is the conjugate base of hydrogenphosphate.
The salt is obtained by partial neutralization of phosphoric acid.
The pKa of monosodium phosphate is 6.8-7.2 (depending on the physicochemical characteristics during pKa determination).
Heating this salt above 169 °C gives disodium pyrophosphate: 2 NaH2PO4 → Na2H2P2O7 + H2O
When heated at 550 °C, anhydrous trisodium trimetaphosphate is formed: 3 NaH2PO4 → Na3P3O9 + 3 H2O
Monobasic sodium phosphate monohydrate, commonly known as sodium dihydrogen phosphate monohydrate, is a chemical compound composed of sodium, phosphate, and water molecules.
It has the chemical formula NaH₂PO₄·H₂O and is typically found as a white, crystalline solid.
Monobasic sodium phosphate monohydrate is often used in a variety of industries, including pharmaceuticals, food processing, and laboratory applications.
In pharmaceuticals, it serves as a buffering agent to maintain a stable pH in oral and injectable formulations, which is essential for the stability and effectiveness of many drugs.
It is also employed in the preparation of phosphate buffers, which are critical in biochemistry and molecular biology experiments.
In laboratory settings, Monobasic sodium phosphate monohydrate is used to prepare solutions with specific pH levels for various tests, such as enzyme assays and protein separation.
Additionally, it is involved in the preparation of reagents for chemical analysis.
In the food industry, it acts as a food additive, helping to regulate acidity and maintain the proper texture and consistency of processed foods.
Chemically, it consists of one sodium ion (Na⁺), one dihydrogen phosphate ion (H₂PO₄⁻), and a single water molecule (H₂O), making it a monohydrate form of sodium phosphate.
This structure allows it to dissolve readily in water, releasing hydrogen ions (H⁺), which makes it effective in controlling pH in aqueous solutions.
In the pharmaceutical industry, Monobasic sodium phosphate monohydrate is a key ingredient in the formulation of buffered solutions, especially in intravenous fluids, where maintaining the correct pH is crucial for the stability and efficacy of active ingredients.
Monobasic sodium phosphate monohydrate is also used in the formulation of saline solutions, where it helps maintain osmolarity and ensures that the solution is compatible with bodily fluids.
The compound's ability to stabilize pH makes it useful in a range of medications, from antacids to injectable drugs.
In laboratory settings, Monobasic sodium phosphate monohydrate is frequently used to prepare phosphate buffer solutions that provide a stable environment for biochemical reactions.
For instance, in protein electrophoresis, where proteins are separated based on their charge and size, a consistent pH is essential to prevent changes in the protein's structure or charge.
Similarly, in molecular biology, it is used in various assay buffers to ensure optimal conditions for enzymatic activity or DNA/RNA integrity.
Melting point: 100 °C
Density: 1.40 g/mL at 20 °C
storage temp.: -20°C
solubility: H2O: 5 M, clear, colorless
form: powder
color: Clear colorless
PH: 1.4 (20°C in H2O)
biological source: rabbit
Monobasic sodium phosphate monohydrate is a versatile and crucial chemical compound, valued for its buffering capabilities, stability in solutions, and wide range of applications in scientific research, pharmaceuticals, food processing, and water treatment.
Monobasic sodium phosphate monohydrate, Crystal, Reagent, ACS is one of the sodium salts derived from phosphoric acid.
Highly hygroscopic and water soluble it comes in the form of a white powder.
It is used commercially in powered products as an anti-caking agent for those qualities.
In a watered solution it is basic, with a pH value between 8.0 and 11.0.
As an ACS grade Reagent, Spectrum Chemical manufactured compound is used as the quality standard against which other substances are grade and has met the toughest regulatory standards for quality and pureness.
The compound also has applications in environmental chemistry, particularly in the context of pollution control.
As a phosphate source, monobasic sodium phosphate monohydrate is sometimes used in the treatment of industrial wastewaters to precipitate metals such as lead, cadmium, and zinc, reducing their toxicity before discharge into the environment.
Monobasic sodium phosphate monohydrates react with heavy metals, forming insoluble precipitates that can be easily removed from the water, thereby improving water quality.
In agriculture, Monobasic sodium phosphate monohydrate may be used as a component in fertilizers or soil amendments.
Phosphorus is an essential nutrient for plant growth, and adding phosphate to the soil helps ensure that plants have access to the phosphorus they need for photosynthesis, root development, and overall plant health.
By providing a controlled and stable source of phosphorus, monobasic sodium phosphate monohydrate aids in enhancing crop yields and improving soil fertility.
Phosphates derived out of orthophosphoric acid are called orthophosphates.
The most common phosphates are calcium dihydrogen phosphate [Ca(H2PO4)4], or single superphosphate and diammonium hydrogen phosphate (NH4)2HPO4 or DAP.
Monobasic sodium phosphate monohydrate is used in the preparation of certain cleaning and detergent formulations, especially those designed for use in the pharmaceutical and food industries, where stringent cleaning standards are required.
Monobasic sodium phosphate monohydrate can help in the removal of mineral deposits and maintain the correct pH for effective cleaning.
The compound also finds its place in water treatment plants, where it is used to adjust the pH of water in processes such as coagulation and flocculation, ensuring that the water meets safety and quality standards.
Moreover, Monobasic sodium phosphate monohydrate is utilized in the food industry as an acidulant, where it can help to adjust the acidity of foods and beverages, ensuring the desired flavor profile and preventing spoilage.
Monobasic sodium phosphate monohydrate’s versatility extends further in various industrial and scientific applications, owing to its highly effective buffering properties and its role as a source of phosphate ions.
It is commonly found in analytical chemistry, where it serves as a critical reagent in a variety of reactions and procedures.
As a buffering agent, it ensures the proper environment for acid-base titrations and is used in the preparation of calibration solutions for pH meters, where accuracy is paramount.
By stabilizing the pH of a solution, it helps prevent errors in the measurement of other chemical components, ensuring precise analytical results.
In the field of microbiology, Monobasic sodium phosphate monohydrate is used to prepare growth media that maintain the optimal pH for microbial cultures.
The ability to control pH is essential for encouraging the growth of specific bacteria or fungi while inhibiting the growth of unwanted microorganisms.
This feature is particularly important when cultivating strains for research or industrial production, such as in the fermentation of antibiotics or other bioactive compounds.
Monobasic sodium phosphate monohydrate plays a significant role in improving the dyeing processes.
It is often included in dye baths as a pH stabilizer to ensure that the dye interacts with the fabric in a consistent manner, leading to more even and durable colorings.
By adjusting and stabilizing the pH of the dye solution, it helps prevent color fading, uneven distribution, or excessive consumption of dye, making the process more efficient and cost-effective.
Monobasic sodium phosphate monohydrate is also important in the cosmetics and personal care industry.
Monobasic sodium phosphate monohydrate is included in certain formulations, such as shampoos, body washes, and facial cleansers, where it serves as a pH adjuster to ensure that the product is neither too acidic nor too alkaline.
Maintaining a balanced pH is essential not only for the product's stability but also for the safety and comfort of consumers, as products that are too acidic or basic can cause irritation to the skin or scalp.
Uses Of Monobasic sodium phosphate monohydrate:
Monobasic sodium phosphate monohydrate is an inorganic compounds.
Monobasic sodium phosphate monohydrate is a essential nutrient, found in many organic compounds including nucleic acids and lipids.
Abundance of it has also been seen to promote cyanobacterial proliferation.
Monobasic sodium phosphate monohydrate also promotes the forming of bones in the form of minerals in the apatite family.
Monobasic sodium phosphate monohydrate has been used as a component of phosphate buffer to maintain the pH for the preparation of collagen gels and matrices.
Monobasic sodium phosphate monohydrates are often used in foods and in water treatment.
The pH of such formulations is generally adjusted by mixtures of various sodium phosphates, such as this salt.
The sodium chloride equivalent value, or E-Value, is 0.49.
Monobasic sodium phosphate monohydrate is soluble in 4.5 parts water.
Monobasic sodium phosphate monohydrate is added in animal feed, toothpaste, and evaporated milk.
Monobasic sodium phosphate monohydrate is used as a thickening agent and emulsifier.
Monobasic sodium phosphate monohydrate is used to detect the presence of magnesium ions in salts.
Formation of a white precipitate on the addition of ammonium chloride, ammonium hydroxide and monosodium phosphate to an aqueous or dilute HCl solution of the salt indicates presence of magnesium ions.
Monobasic sodium phosphate monohydrate, also known as sodium dihydrogen phosphate monohydrate, is used in a wide array of industries due to its unique ability to regulate pH levels and serve as a buffer in various applications.
One of its primary uses is in the pharmaceutical industry, where it functions as a buffering agent in intravenous solutions, oral medications, and other pharmaceutical formulations.
Its role in maintaining a stable pH is crucial for preserving the efficacy and stability of active pharmaceutical ingredients, particularly in injectable solutions that need to match the body’s natural pH levels to avoid irritation or precipitation.
In laboratory settings, monobasic sodium phosphate monohydrate is commonly used in the preparation of phosphate buffer solutions, which are essential in biochemical and molecular biology experiments.
These buffers are used in a variety of processes, including enzyme assays, protein electrophoresis, and DNA/RNA extraction.
Monobasic sodium phosphate monohydrate ensures that the pH of the solution remains consistent, which is vital for the proper function of enzymes and the successful separation of biomolecules.
It is also used in creating calibration standards for pH meters and in performing acid-base titrations.
The compound is also utilized in the food industry, where it is added as a food additive to control the acidity of certain processed foods.
In foods such as cheeses, jams, and meats, monobasic sodium phosphate monohydrate can help preserve texture, prevent spoilage, and enhance the shelf-life of the product.
Its buffering properties ensure that food maintains its desired pH balance, which is important for both flavor and food safety.
Additionally, Monobasic sodium phosphate monohydrate can be used in the preparation of phosphate-based preservatives that help keep products fresh for longer periods.
In the water treatment industry, monobasic sodium phosphate monohydrate is employed to adjust the pH of water in various processes, such as coagulation, flocculation, and sedimentation.
The compound helps control the pH level of water used for municipal or industrial applications, ensuring that water is properly treated before being released into the environment.
It is particularly effective in reducing the presence of heavy metals in water by facilitating their precipitation, making it an essential component in environmental pollution control.
Another significant application of Monobasic sodium phosphate monohydrate is in the textile industry, where it is used in dyeing processes to maintain the correct pH of the dye bath.
By stabilizing the pH, it ensures that the dyes adhere uniformly to fabrics, resulting in even coloration and preventing issues such as fading or uneven dye uptake.
This makes it a key ingredient in the production of textiles that require consistent and vibrant coloring.
In the agriculture sector, Monobasic sodium phosphate monohydrate is sometimes utilized as a fertilizer component, providing plants with a source of phosphate.
Phosphorus is an essential nutrient for plants, aiding in root development, energy transfer, and overall growth.
By adding phosphate to the soil in a controlled manner, the compound helps improve soil fertility and supports the growth of healthy crops, ultimately boosting agricultural yields.
In the cosmetics and personal care industries, monobasic sodium phosphate monohydrate is used to adjust the pH of products like shampoos, conditioners, and skin care formulations.
By maintaining the correct pH balance, it ensures that these products are gentle and effective when applied to the skin or hair, preventing irritation or damage.
The compound is also used in the formulation of certain cleansers, where its buffering action ensures that the products remain effective at removing dirt and oil without disrupting the natural pH of the skin.
Additionally, Monobasic sodium phosphate monohydrate is employed in specialized cleaning products, particularly in industrial and pharmaceutical cleaning applications.
Its role in cleaning involves adjusting the pH of cleaning solutions to ensure that they can effectively remove mineral deposits, oils, and other residues from equipment and surfaces, ensuring hygienic conditions in environments that require stringent cleanliness standards.
Monobasic sodium phosphate monohydrate serves many crucial functions across a variety of industries.
From pharmaceutical formulations and laboratory research to food processing, water treatment, textile manufacturing, agriculture, and cosmetics, its ability to stabilize pH and provide a reliable source of phosphate makes it an invaluable chemical compound in both commercial and industrial applications.
Safety Profile Of Monobasic sodium phosphate monohydrate:
As a mildly acidic substance, monobasic sodium phosphate monohydrate can cause irritation if it comes into direct contact with the skin or eyes.
Prolonged exposure can lead to redness, discomfort, or more severe irritation, depending on the concentration.
In case of eye contact, it can cause burning sensations, redness, or watering.
Inhalation of dust or vapor from the compound, especially in its dry form, may irritate the respiratory system.
Inhalation of large quantities could cause coughing, shortness of breath, or a sore throat.
This is particularly a concern in environments where the compound is used in bulk quantities or in confined spaces without proper ventilation.
If ingested in significant amounts, Monobasic sodium phosphate monohydrate can cause gastrointestinal irritation, resulting in symptoms like nausea, vomiting, or diarrhea.
While the compound is not considered acutely toxic, ingestion of large amounts can lead to electrolyte imbalances or mild poisoning.