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MONTANOX 20

Formula: C58H114O26
Molecular weight: 1227.72 g/mol
Cas Number: 9005-64-5

APPLICATIONS

Montanox 20 is an hydrophilic O/W emulsifier, for all types of application and texture.
Further, Montanox 20 is an xcellent solubilizing agent for lipophilic compounds such as essential oils and fragrances.

Montanox 20 can be used for all types of product:

Make-up removal
Deodorant
Hair
Suncare
Make-up

Montanox 20 is used for production of personal care products:

Facial cleansing gels
Tonics
Shampoos

Montanox 20 has a suitable grade for every application.
Furthermore, Montanox 20 range is composed of monoesters of lauric, stearate or oleic fatty acids.
Montanox 20 has a degree of ethoxylation of 20 and is characterized by its HLB (Hydrophilic-Lipophilic Balance).

Montanox 20 is designed for injectable administration and products are manufactured according to the Good Manufacturing Practices “GMP part II” and comply with the EP, USP and JP or JPE pharmacopoeia.
Montanox 20 is designed for oral and topical administration and products are manufactured according to IPEC’s GMPs and comply with the EP and USP pharmacopoeia.

Food applications of Montanox 20:

Montanox 20 is used as a wetting agent in flavored mouth drops such as Ice Drops, helping to provide a spreading feeling to other ingredients like SD alcohol and mint flavor.

Biotechnical applications of Montanox 20:

In biological techniques and sciences, Montanox 20 has a broad range of applications.

For example, Montanox 20 is used as a washing agent in immunoassays, such as Western blots and ELISAs.
Montanox 20 helps to prevent non-specific antibody binding.

In this major application, Montanox 20 is dissolved in Tris-buffered saline or phosphate buffered saline at dilutions of 0.05% to 0.5% v/v.
These buffers are used for washes between each immunoreaction, to remove unbound immunologicals, and eventually for incubating solutions of immunoreagents (labeled antibodies) to reduce nonspecific background.

Montanox 20 is used to saturate binding sites on surfaces (i.e., to coat polystyrene microplates, generally combined with proteins such as BSA).
Further, Montanox 20 can be used to stabilize proteins purified protein derivative (PPD) solution used in skin testing for tuberculosis exposure.

Montanox 20 is used as a solubilizing agent of membrane proteins.
Moreover, Montanox 20 can be used for lysing mammalian cells, at a concentration of 0.05% to 0.5% v/v, generally combined with other detergents, salts and additives.

Pharmaceutical applications of Montanox 20:

Montanox 20 is used as an excipient in pharmaceutical applications to stabilize emulsions and suspensions.

Industrial and domestic applications of Montanox 20:

Montanox 20 is used in many brands of baby wipes.
Further, Montanox 20 is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself.

Montanox 20 is also used as wetting agent in rubber balers in the elastomer industry.
More to that, Montanox 20 has been used as a shape directing agent to synthesize spheroidal magnetite nanoassemblies.

Montanox 20 is a membrane protein solubilizing non-ionic surfactant.
Furthermore, Montanox 20 is used as a wetting agent in flavored mouth drops such as Ice Drops, helping to provide a spreading feeling to other ingredients like SD alcohol and mint flavor.

Montanox 20 acts as an emulsifier for Oil/water systems and effective solubiliser for essential oils and perfumes in aqueous or aqueous/alcoholic systems.
Montanox 20 is used in skin care creams and lotions, clear systems eg. gels, hair care products, sun care, aftershaves, colognes, wetwipes, bath as well as shower products, cleaners, toners, specific skin care treatments, baby care, male grooming, shaving, color cosmetics and oral care.

Montanox 20 is used for solubilizing membrane proteins during isolation and purification.
More to that, Montanox 20 is used as a wetting agent in flavored mouth drops.
Montanox 20 acts as a washing agent in Western blots and ELISAs and prevents antibody binding.

Montanox 20 is a solubilizing agent of membrane proteins.
In pharmaceutical chemistry, Montanox 20 is used as an excipient to stabilize emulsions and suspensions.
Further, Montanox 20 is used as a dispersing agent, stabilizer, lubricator and also used in creams, salves, ointments, protective creams, balms, pomades, lipsticks, mascaras and glosses.

Montanox 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water.

DESCRIPTION


Montanox 20 emulsifies all types of oil in combination with a lipophilic emulsifier.
Further, Montanox 20 is a solubilizing agent for fat-soluble compounds and fragrances in continuous aqueous mediums (make-up removers, shampoos, etc.).

Montanox 20 can be applied to a variety of textures, from spray to butter.
Furthermore, Montanox 20 has a light, neutral feel.

Montanox 20 has excellent eye and skin tolerance.
Moreoveri Montanox 20 is preservative-free.

Montanox 20 acts as hydrophilic o/w emulsifier, for all types of application and texture.
More to that, Montanox 20 is used as excellent solubilizing agent for lipophilic compounds such as essential oils and fragrances.

Montanox 20 offers light, neutral feel, excellent eye and skin tolerance.
Further, Montanox 20 is preservative-free.
Montanox 20 is used in make-up removal, deodorant, hair, sun-care, make-up, facial cleansing gels, tonics and shampoos.

Montanox 20 is composed of different grades of polysorbates that can be used to solubilize active pharmaceutical and/or biological ingredients and to formulate oil-in-water emulsions for oral, topical and injectable products.

Montanox 20 is polyethoxylated sorbitan esters.
Furthermore, Montanox 20 plays a triple role:
Montanox 20 is used as emulsifier to formulate oil in water emulsions but also as solubilizers for active ingredients with low solubility and also as antiaggregants for biological active ingredients.

Montanox 20 is stable in acidic or basic media and in the presence of electrolytes and are compatible with other surfactants.
They can be combined with Montanox 20 to produce highly stable emulsions.

Montanox 20 acts as an emulsifier to formulate oil in water emulsions but also as hydrophilic solubilizers for active ingredients with low solubility. 
Moreover, Montanox 20 is composed of monoesters of lauric, stearate or oleic fatty acids. 
Montanox 20 is compatible with other surfactants and produce highly stable emulsions.

Montanox 20 is stable in acidic or basic media and in presence of electrolytes.
Further, Montanox 20 is used in cosmetic products.


The stability and relative nontoxicity of Montanox 20 allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications.
As the name implies the ethoxylation process leaves the molecule with 20 repeat units of polyethylene glycol; in practice these are distributed across 4 different chains, leading to a commercial product containing a range of chemical species.


Montanox 20 is a polyoxyethylene sorbitol ester containing approximately 20 units of ethylene oxide per unit of sorbitol.
The fatty acid composition is heterogeneous with lauric acid as major component (40 - 60 %).

Montanox 20 is of importance in immunological determination procedures.
Further, Montanox 20 effectively suppresses unspecific reactions between antibodies, antigens, and other molecules.

Montanox 20 can also be used as a solubilizer in membrane chemistry and as an additive for cell culture media.

In thiophilic interaction chromatography, Montanox 20 has proved effective in the elution of strongly adsorbed proteins.

Other notable applications are e.g. turbidimetric determination of lipolytic enzymes and density gradient centrifugation of viruses.

Montanox 20 (9005-64-5) is a clear, yellow to yellow-green viscous liquid.

Storage of Montanox 20:

Keep container of Montanox 20 tightly closed.
Keep container of Montanox 20 in a cool, well-ventilated area.

Waste Disposal:
Waste must be disposed of in accordance with federal, state and local environmental control regulations.


Its stability and relative nontoxicity allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications.
As the name implies the ethoxylation process leaves the molecule with 20 repeat units of polyethylene glycol; in practice these are distributed across 4 different chains, leading to a commercial product containing a range of chemical species.


Montanox 20 is allowed to be used as the emulsifier, detergent, dispersant, solvent and stabilizer, etc. in a number of fields such as pharmaceutical, chemical, food, textile and other industries due to its stability and relative non-toxicity.

Montanox 20 is widely applied in biological techniques and sciences, which can be added to buffers and reagents for immunohistochemistry, such as Western blots and ELISAs, helping to prevent non-specific antibody binding, decrease background staining and enhance reagent spreading.
Besides, Montanox 20 also has applications in food production as a common food grade additive which are found in many consumables on the market today.
Montanox 20 can also be used as a wetting agent in flavored mouth drops such as Ice Drops, in oral or non-gastrointestinal suspensions and in rubber balers in the elastomer industry.

Montanox 20 is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides.
Furthermore, Montanox 20 has a faint, characteristic odor and a warm, somewhat bitter taste.

Montanox 20 (Tween 20) is a polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group.
More to that, Montanox 20 is a surfactant and emulsifier used in cleaners and personal care products.

Montanox 20 is a hydrophilic nonionic surfactant generally used as emulsifiers, dispersing agent and solubilizer.

PROPERTIES


DNases/RNases/Proteases: not detectable
Density (d 20°C/4°C): 1.095 - 1.105
Hydroxyl-No.: approx. 100
Saponification No.: 40 - 50
CMC (25°C): 5.9 x 10-5 mol/l
Classification: nonionic detergent
Solubility: (25°C in water) 100 g/l
Boiling point: > 100°C
Colour to Gardner: max. 6
Appearance: Light yellow oily liquid
Acid Value: 2.0mg KOH/g max.
Saponification Value: 40~50 mg KOH/g
Hydroxyl Value: 96~108 mg KOH/g
Residue on Ignition: 0.25% max.
Water: 3.0% max.
Lead: 2mg/kg max.
Oxyethylene: 70.0%~74.0%
Appearance (Color): Light Green-Yellow to Green-Yellow and Faint Yellow to Dark Yellow
Appearance (Form): Viscous Liquid
Appearance (Turbidity): Clear
Purity (GC): > 40 % _
GC: Corresponds to Requirements as Lauric Acid (Balance Primarily Myristic, Palmitic, and Stearic Acids)
Solubility (Color): Colorless to Yellow
Solubility (Turbidity): Clear
    100 mg/ml in H2O
Water: < 3.0 % _
Infrared Spectrum: Conforms to Structure
Acid Value: < 2.2 mg/g _
    mg KOH/g
Hydroxyl value 96 - 108 mg/g
    mg KOH/g
Saponification Value: 40 - 50 mg/g
    mg KOH/g
Melting point: 98.9 °C (decomp)
Boiling point: 100 °C
density: 1.11 g/mL at 20 °C
vapor pressure: <1.4 hPa (20 °C)
refractive index: n20/D 1.468(lit.)
FEMA: 2915 | Montanox 20
Fp: >230 °F
storage temp.: Store below +30°C.
solubility: 100 g/L
form: viscous liquid
color: Amber
Specific Gravity: 1.090~1.130 (20/20℃)
PH: 6-8 (50g/l, H2O, 20℃)
PH Range: 7
Water Solubility: 100 g/L

FIRST AID


Ingestion:

Wash out mouth with water.
Remove victim to fresh air and keep at rest in a position comfortable for breathing.
If material has been swallowed and the exposed person is conscious, give small quantities of water to drink.

Do not induce vomiting unless directed to do so by medical personnel.
Get medical attention if symptoms occur.

Eye contact:

Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids.
Check for and remove any contact lenses.
Get medical attention if irritation occurs.

Skin contact:

Flush contaminated skin with plenty of water.
Remove contaminated clothing and shoes.
Get medical attention if symptoms occur.

Inhalation:

Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical attention if symptoms occur.

HANDLING AND STORAGE


Put on appropriate personal protective equipment.
Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed.

Workers should wash hands and face before eating, drinking and smoking.
Remove contaminated clothing and protective equipment before entering eating areas.
Do not inject

Store Montanox 20 in accordance with local regulations.
Store Montanox 20 in original container protected fromdirect sunlight in a dry, cool and well-ventilated area, away from incompatible materials and food and drink.

Keep container of Montanox 20 tightly closed and sealed until ready for use.
Containers of Montanox 20 that have been opened must be carefully resealed and kept upright to prevent leakage.

Do not store in unlabelled containers.
Use appropriate containment to avoid environmental contamination.
Store under cover.

SYNONYMS

Kolliphor PS 20
Montanox 20
Montanox 20
PEG(20)sorbitan monolaurate
Alkest TW 20
Tween 20
Kotilen-20
Montanox 20
Montanox 20
psml
capmul
TWEEN 20
Twain 20
FEMA 2915
'TWEEN' 20
emsorb6915
TWEEN(R) 20
TWEEN(R) 21
TWEEN 20(R)
TWEEN NO 20
TWEEN(TM) 20
TWEEN(TM) 21
Montanox 20(TM)
hodagpsml-20
liposorbl-20
Tween 20 1LT
TWEEN 20PURE
Tween(rg 20
Tween 20 
protasorbl-20
armotanpml-20
EMALEX ET-2020
Montanox 20
POLYSORBATE 21
EmulsifierT-20
glycospersel-20
TWEEN(-1)(R) 20
TWEEN 20 EP, NF
POLYSORBATUM 20
emulsifier(t20)
dxewmulsepoe-sml
glycospersel-20x
TWEEN 20 BP GRADE
POLYSORBATE,20,NF
Montanox 20/80
Montanox 20(Tween20)
POLYSORBATE,20,FCC
POLYSORBATE,20(BULK
Montanox 20, USP
SURFACT-AMPS(TM) 20
SORBITAN MONOLAURATE
Montanox 20 (2 g)
Polisorbate 20- PS 20
POLYSORBAT 20, PH EUR
Tween20=Polysorbate20
PROTEIN SOLUBILIZER 20
TWEEN(R) 20 POLYSORBATE
TWEEN(R) Montanox 20
sorbimacrogollaurate300
PEG-10 SORBITAN LAURATE
PEG-40 SORBITAN LAURATE
PEG-44 SORBITAN LAURATE
PEG-75 SORBITAN LAURATE
PEG-80 SORBITAN LAURATE
Tween 20, Ph. Eur. & USP
Montanox 20 extrapure
Tween 20, synthesis grade
Montanox 20 (2 g) (AS)
TWEEN(R) 20 250-450 MPA.S
Tween(R) 20,Ph. Eur. & USP
ZYP-5052 AUTOINDUCTION MEDIA
TWEEN 20 CELL CULTURE REAGENT
POE (20) SORBITAN MONOLAURATE
TWEEN 20 ELECTROPHORESIS GRADE
PESTLE AND TUBE 1.5ML ASSORTED
TWEEN 20MOLECULAR BIOLOGY GRADE
Polysorbatum 20, Tween(R) 20
SURFACTANTS(glyceryl monosterate
POLYOXYETHYLENE (20) MONOLAURATE
SORBITANPOLYOXYETHYLENEMONOLAURATE
TWEEN(R) 20 BIOXTRA, VISCOUS LIQUID
POLYOXYETHYLENESORBITAN MONOLAURATE
POLYOXYETHYLENE SORBITAN MONOLAUREATE
POLYOXYLETHYLENE SORBITAN MONOLAURATE
POLYOXYETHYLENE(2)SORBITANMONOLAURATE
POLYOXETHYLENE(20)SORBITANMONOLAURATE
POLYOXYETHYLENE(6)SORBITANMONOLAURATE
Montanox 20, Electrophoresis Grade
Tween(R) 20 (Polysorbate), NF, Ph Eur
Sorbitanmonolaurat, ethoxyliert, 20-EO
POLYETHOXYETHANOL SORBITAN MONOLAUREATE
POLY(OXYTHEYLENE)N-SORBITAN-MONOLAURATE
POLYETHYLENE GLYCOL SORBITAN MONOLAURATE
POLYOXYETHYLENE (4) SORBITAN MONOLAURATE
POLYOXYETHYLENE(80) SORBITAN MONOLAURAT&
Montanox 20,Polysorbatum 20, Tween 20
TWEEN(R) 20 Vetec(TM) reagent grade, 40%
ACRYL/BIS 37.5:1 PREMIXED PWD ULTRA PURE
Tween 20 (Trademark of ICI America, Inc.)
Sorbitan monolaureate, ethoxylated (4 EO)
POLYOXYETHYLENE (20) SORBITAN MONOLAURATE
POLYOXYETHYLENE (80) SORBITAN MONOLAURATE
POLYOXYLETHYLENE (20) SORBITAN MONOLAURATE
ProteinSolubilizer20,ReadytouseAmpules,Sterile
polyoxyethylene sorbitan monolauric acid ester
Polyoxyethylene sorbitan monolaurate (Tween 20)
Tween20(Polyoxyethylene-20-SorbitanMonolaurate)
POLYOXYETHYLENESORBITAN MONOLAURATE*(TWE EN 21)
POLYOXYETHYLENESORBITAN MONOLAURATE*SIGM AULTRA
Tween 20 (=Polyoxyethylene Sorbitan Monolaurate)
polyethylene glycol sorbitan monolaurate solution
polyoxyethylene (20)sorbitan monolaurate solution
polyoxyethylene (80) sorbitan monolaurate solution
POLYOXYETHYLENESORBITAN MONOLAURATE*ELEC TROPHORESIS
POLYOXYETHYLENE SORBITAN MONOLAURATE*(TW EEN 20), LO
POLYOXYETHYLENESORBITAN MONOLAURATE*CELL CULTURE TE
POLYOXYETHYLENESORBITAN MONOLAURATE*MOLE CULAR BIOLO
POLYOXYETHYLENE SORBITAN MONOLAURATE*(TW EEN 20), PR
Sorbitan,monodadecanoate,poly(oxy-1,2-ethanediyl)derivs.
sorbitan,monododecanoate,poly(oxy-1,2-ethanediyl)derivs.
sorbitan,monododecanote,poly(oxy-1,2-ethanediyl)derivatives
POLYOXYETHYLENE (20) SORBITAN MONOLAURATE SOLUTION, 70% WATER
POLYOXYETHYLENE (20) SORBITAN MONOLAURATE SOLUTION, 72 WT.% IN WATER
POLYOXYETHYLENE (20) SORBITAN MONOLAURATE SOLUTION, BIOCHEMIKA, ~10% WATER
Tween 20 (=Polyoxyethylene Sorbitan Monolaurate) [for Biochemical Research]
Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate
TWEEN 20,Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate
Polyethylene glycol sorbitan monolaurate solution, Polyoxyethylenesorbitan monolaurate
TWEEN 20,Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate, Montanox 20
Montanox 20, Polyoxyethylene (20) sorbitan monolaurate, PEG(20)sorbitan monolaurate
PEG (20) sorbitan monolaureate
Polisorbate 20- PS 20
Tween 20 (Trademark of ICI America, Inc.)
Tween 20 
Tween 20 1LT;Twain 20;TWEEN(R) 20 Vetec(TM) reagent grade, 40%
ACRYL/BIS 37.5:1 PREMIXED PWD ULTRA PURE
TWEEN 20 ELECTROPHORESIS GRADE
Ahco 7596T; Alkamuls PSML 20
Alkamuls PSML 80/72
Alkamuls T 20; Alkest TW 20
Anapoe 20; Armotan PML 20
Atlas G 4280; Atlas G 7596J; Atlas G 7596P
Atmer 110; Canarcel TW 20; Coulter Dispersant IB
Cremophor PS 20; Crillet 1; Crillet 1HP; D 941
Disponil SML 120; Disponil SML 20; E 432
Emasol 1112
Emasol L 120V
Emasol L 130
Emsorb 6915
Ercasorb 2020
Ethoxylated Sorbitan Monolaurate
Ethsorbox L 20
Ethylene Oxide-sorbitan Monolaurate Adduct; Ethylene Oxide-sorbitan Monolaurate Polymer; Eumulgin SML 15; Eumulgin SML 20; G 1020; G 4280; G 7596J
G 7606J; GL 1; Glycosperse L 20K
Glytanox 1001; Ionet T 20C; Kaopan TW-L 120
Kemotan T 20; Kolliphor PS 20; LT 221
Lamesorb SML 20; Liposorb L 20; Lumisorb PSML-80
ML 55F; Monopol Twl 1030; Montanox 20
Nikkol LT 221; Nikkol TL 10; Nissa

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