A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6.
Morinda officinalis Root extract is a natural anthraquinone.
Morinda officinalis Root extract has been reported to have laxative and anti-inflammatory actions, inhibit kinases and tyrosinase, and have cytotoxicity against cancer cells.
CAS: 521-61-9
MF: C16H12O5
MW: 284.26
EINECS: 208-315-7
Synonyms
;3-methoxy-6-methyl-;1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthraquinone;EMODIN-3-METHYLETHER;(RG)(CALL);1,8-Dihydroxy-3-Methoxy-6-Methyl-;Rheochrysidin (Physcione);MethyleModin;Physcic acid;Przewalskinone B;Physcion;521-61-9;Physcione;Parietin;Rheochrysidin;Emodin 3-methyl ether;1,8-Dihydroxy-3-methoxy-6-methylanthraquinone;Emodin-3-methyl ether;1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione;Parienin;NSC 251670;Emodin monomethyl ether;1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione;CCRIS 4399;1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone;Rheochrysidin (Physcione);EINECS 208-315-7;UNII-H6PT94IV61;BRN 1915778;H6PT94IV61;Parietin;Rheochrysidin;PHYSCIONE-;1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinone;ANTHRAQUINONE, 1,8-DIHYDROXY-3-METHOXY-6-METHYL-;6-O-METHYLEMODIN;MFCD00017374;NSC251670;NSC-251670;CHEMBL42624;9,10-Anthracenedione, 1,8-dihydroxy-3-methoxy-6-methyl-;CHEBI:38167;DTXSID20200101;CHRYSOPHANIC ACID, 6-METHOXY-;Methoxyemodin;fischione;Physcion,(S);Spectrum_001782;9,10-dione;SpecPlus_000471;Spectrum2_000503;Spectrum3_001829;Spectrum4_000909;Spectrum5_001742;1,8-Dihydroxy-3-methoxy-6-methyl-anthraquinone;BSPBio_003477;KBioGR_001378;KBioSS_002265;Physcion, analytical standard;DivK1c_006567;SCHEMBL486155;SPECTRUM1504070;SPBio_000425;MEGxm0_000018;KBio1_001511;KBio2_002264;KBio2_004832;KBio2_007400;KBio3_002981;1,8-dihydroxy-3-methoxy-6-methyl-anthracene-9,10-dione;DTXCID80122592;HMS3656I15;HMS3874M13;Physcion, >=98.0% (TLC);EX-A6797;HY-N0108;EMODIN 3-METHYL ETHER [MI];BDBM50005886;CCG-38713;s2395;AKOS015905689;AC-7979;KS-5385;SDCCGMLS-0066772.P001;NCGC00096075-01;NCGC00096075-02;NCGC00096075-03;1ST40046;9, 1,8-dihydroxy-3-methoxy-6-methyl-;AS-15488;DA-66695;NCI60_002011;CS-0007795;NS00010362;SW219324-1;1,8-dihydroxy-3-methoxy-6-methylanthracene-;1,8-dihydroxy-6-methoxy-3-methylanthraquinone;Anthraquinone,8-dihydroxy-3-methoxy-6-methyl-;C17045;SR-05000002537;Q-100587;Q1668551;SR-05000002537-1;8,9-dihydroxy-3-methyl-6-methoxy-1,10-anthraquinone;8,9-dihydroxy-6-methyl-3-methoxy-1,10-anthraquinone;BRD-K67772619-001-03-6;BRD-K67772619-001-05-1;1,8-Dihydroxy-3-methoxy-6-methylanthra-9,10-quinone #;7-methoxy-2-methyl-4,5-dihydroxyanthracene-9,10-dione;1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, Emodin-3-methyl ether
Morinda officinalis Root extract inhibits 6-phosphogluconate dehydrogenase (IC50 = 38.5 µM), decreasing lipogenesis and RNA biosynthesis in cancer cells, leading to reduced cell proliferation and tumor growth in mice.
Morinda officinalis Root extract is a dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6.
Morinda officinalis Root extract has been widely isolated and characterised from both terrestrial and marine sources.
Morinda officinalis Root extract has a role as an apoptosis inducer, an antineoplastic agent, a hepatoprotective agent, an anti-inflammatory agent, an antibacterial agent, an antifungal agent and a metabolite.
Morinda officinalis Root extract is functionally related to a 2-methylanthraquinone.
A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6.
Morinda officinalis Root extract has been widely isolated and characterised from both terrestrial and marine sources.
Morinda officinalis Root extract Chemical Properties
Melting point: 196-206°C
Boiling point: 560.5±50.0 °C(Predicted)
Density: 1.448±0.06 g/cm3(Predicted)
Storage temp.: -20°C Freezer, Under Inert Atmosphere
Solubility: Chloroform (Slightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Slightly)
Form: Solid
pka: 6.23±0.20(Predicted)
Color: Yellow to Dark Yellow to Dark Orange
BRN: 6770499
Stability: Hygroscopic
InChIKey: FFWOKTFYGVYKIR-UHFFFAOYSA-N
LogP: 5.078 (est)
CAS DataBase Reference: 521-61-9(CAS DataBase Reference)