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CAS NUMBER: 9004-74-4
EC NUMBER: 203-962-1
MOLECULAR FORMULA: C7H16O4
MOLECULAR WEIGHT: 164.20
IUPAC NAME: 2-[2-(2-methoxyethoxy)ethoxy]ethanol
MPEG 2000 is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE; Item No. 15095).
Formulations containing MPEG 2000 have been used in the synthesis of liposomes for the delivery of anticancer and antimalarial agents.
MPEG 2000 is a phospholipid PEG conjugate, has both hydrophilicity and hydrophobility.
MPEG 2000 is used in the synthesis of liposomes, increases the hydrophilicity on the surface of liposomes, consequently increasing the longevity of liposomes in the blood circulation for the study of anticancer and antimalarial agents
MPEG 2000 was used to study stability and biodistribution of lung-specific liposomal antitubercular drugs.
MPEG 2000 has been used in the synthesis of liposomes for the delivery of anticancer and antimalarial agents.
MPEG 2000 is a phospholipid PEG conjugate, has both hydrophilicity and hydrophobility.
MPEG 2000 is used in the synthesis of liposomes, increases the hydrophilicity on the surface of liposomes, consequently increasing the longevity of liposomes in the blood circulation for the study of anticancer and antimalarial agents
APPLICATIONS:
-Medical research
-Drug release
-Nanotechnology
-New materials research
-Cell culture
-Ligand
-Polypeptide synthesis support
-Vaccine polymer compounds
-Modified functional skins
MPEG 2000 is a derivative of phosphatidylethanolamine and is used to increase the circulation time of liposomes and lipid nanoparticles (LNPs) in vivo.
The hydrophilic MPEG 2000 chains decrease interactions with the reticular-endothelial system and increases the size of the particles both of which result in lowered clearance rate from the body.
MPEG 2000 is used in COVID 19 mRNA vaccines.
MPEG 2000 is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE
Formulations containing MPEG 2000 have been used to prepare liposomes with long circulation time for the delivery of anticancer and antimalarial agents..
MPEG 2000 has also been widely used as hydrophilic surface modifying agent for a variety types of hydrophobic nanoparticles, including recently reported lipid nanoparticle mRNA vaccines.
MPEG 2000 is a hydroxypolyether that is the monomethyl ether derivative of triethylene glycol.
Metabolite observed in cancer metabolism.
MPEG 2000 has a role as a human metabolite.
MPEG 2000 is functionally related to a triethylene glycol.
MPEG 2000 is a colorless odorless liquid.
MPEG 2000 is a natural product found in Euglena gracilis with data available.
MPEG 2000 is a PEG chain having one functional group blocked with a methyl group.
MPEG 2000 derivatives are therefore useful for modification of compounds where cross-linking should be avoided.
MPEG 2000 is a PEG linker containing a hydroxyl group.
The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
The hydrophilic MPEG 2000 spacer increases solubility in aqueous media.
MPEG 2000 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.
MPEG 2000 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
MPEG 2000 of with an average molecular mass of 164.
MPEG 2000 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.
MPEG 2000 is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of methyl ether.
Advantages of the product:
-Effective component of PCE superplasticizing admixtures,
-Very good hygroscopic properties,
-Low diol content,
-Paste/soft wax consistency,
-High solubility in water,
-Slight odour
Etherification of the MPEG 2000 chain ends can be undertaken in basic conditions by reacting it with alkyl halides.
MPEG 2000 can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.
MPEG 2000 is a hydrophilic polymer that is used to control the flexibility of a composite.
MPEG 2000 can be used for a variety of applications such as drug delivery, tissue engineering, and other biological uses.
MPEG 2000 is a PEG chain having one functional group blocked with a methyl group. mPEG and mPEG derivatives are therefore useful for modification of compounds where cross-linking should be avoided.
MPEG 2000 is a high molecular weight product that belongs to methoxy polyoxyethylene glycols.
MPEG 2000 is intended mainly for the construction industry.
MPEG 2000 is a white solid.
MPEG 2000 is a polymer with high solubility in water and a slight odour.
MPEG 2000 is used in the synthesis of superplasticizers (concrete admixtures),
MPEG 2000 is used in the synthesis of pigment dispersants.
PHYSICAL PROPERTIES:
-Molecular Weight: 164.20
-XLogP3: -1
-Exact Mass: 164.10485899
-Monoisotopic Mass: 164.10485899
-Topological Polar Surface Area: 47.9 Ų
-Melting Point: 53-54°C
-Storage Temperature: -20°C Freezer
-Physical Description: colorless odorless liquid
-Color: Colorless
-Form: Liquid
-Boiling Point: 246 °C
-Melting Point: -44 °C
-Flash Point: 245 °F
-Solubility: Soluble in water
-Density: 1.0494
-Vapor Pressure: 0.0035 mmHg
-Autoignition Temperature: 210 °C
-Surface Tension: 31.4 dynes/cm
-Chemical Classes: Solvents -> Glycol Ethers
MPEG 2000 is a phospholipid PEG conjugate, has both hydrophilicity and hydrophobility.
MPEG 2000 is used in the synthesis of liposomes, increases the hydrophilicity on the surface of liposomes, consequently increasing the longevity of liposomes in the blood circulation for the study of anticancer and antimalarial agents
MPEG 2000 is used in the synthesis of liposomes, increases the hydrophilicity on the surface of liposomes, consequently increasing the longevity of liposomes in the blood circulation for the study of anticancer and antimalarial agents
MPEG 2000 is a derivative of phosphatidylethanolamine and is used to increase the circulation time of liposomes and lipid nanoparticles (LNPs) in vivo.
MPEG 2000 is used in COVID 19 mRNA vaccines.
MPEG 2000 is a hydroxypolyether that is the monomethyl ether derivative of triethylene glycol.
CHEMICAL PROPERTIES:
-Hydrogen Bond Donor Count: 1
-Hydrogen Bond Acceptor Count: 4
-Rotatable Bond Count: 8
-Heavy Atom Count: 11
-Formal Charge: 0
-Complexity: 67.5
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes
MPEG 2000 is functionally related to a triethylene glycol.
MPEG 2000 is a colorless odorless liquid.
MPEG 2000 is a natural product found in Euglena gracilis with data available.
MPEG 2000 is a hydrophilic polymer that is used to control the flexibility of a composite.
MPEG 2000 can be used for a variety of applications such as drug delivery, tissue engineering, and other biological uses.
MPEG 2000 is a white solid.
MPEG 2000 is a polymer with high solubility in water and a slight odour.
MPEG 2000 is used in the synthesis of superplasticizers.
MPEG 2000 is used in the synthesis of pigment dispersants.
SYNONYMS:
1,2-Distearoyl-rac-glycero-3-PE-N-Polyethyleneglycol-2000
1,2-Distearoyl-rac-glycerol-3-Phosphatidylethanolamine-N-Polyethyleneglycol-2000
1,2-Distearoyl-rac-glycerol-3-Phosphoethanolamine-N-Polyethyleneglycol-2000
1,2-DSPE-MPEG(2000)
alpha-[6-Hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-omega-methoxy-poly(oxy-1,2-ethanediyl)
DSPE-mPEG2K
DSPE-MPEG1000
DSPE-MPEG10000
MPEG-2000-DSPE
DSPE-PEG,MW:3400
MPRG-2000-DSPE-Na
DSPE-PEG2000，>95%
Methyl-PEG2000-DSPE
MPEG-2000-DSPE,99%+
MPEG-2000-DSPE
147867-65-0
DSPE-mPEG2000
PEG2000-DSPE
156543-00-9
sodium;[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate
247925-28-6
Methyl-PEG2000-DSPE
m-PEG-DSPE, MW 550
m-PEG-DSPE, MW 1,000
m-PEG-DSPE, MW 2,000
m-PEG-DSPE, MW 5,000
BP-25268
BP-25269
BP-25271
BP-27962
HY-112760
CS-0063337
1,2-Distearoyl-ras-glycero-3-PE-N-Polyethyleneglycol-2000
1,2-Distearoyl-ras-glycerol-3-Phosphatidylethanolamine-N-Polyethyleneglycol-2000
1,2-Distearoyl-ras-glycerol-3-Phosphoethanolamine-N-Polyethyleneglycol-2000
alpha-[6-hydroxy-6-oxido-1,12-dioxo-9
mPEG2000-DSPE
1,2-Distearoyl-ras-glycero-3-PE-N-Polyethyleneglycol-2000
TRIETHYLENE GLYCOL MONOMETHYL ETHER
112-35-6
2-(2-(2-Methoxyethoxy)ethoxy)ethanol
m-PEG3-alcohol
Methyltrioxitol
Methoxytriglycol
2-[2-(2-Methoxyethoxy)ethoxy]ethanol
Dowanol TMAT
Methyltriglycol
Methoxytriethylene glycol
3,6,9-Trioxa-1-decanol
Poly-Solv TM
Methyl triethylene glycol
Triglycol monomethyl ether
Triethylene glycol methyl ether
Ethanol, 2-[2-(2-methoxyethoxy)ethoxy]-
Triethylene glycolmonomethyl ether
mPEG3-OH
NSC 97395
3,6,9-trioxadecanol
m-PEG3-OH
Ethanol, 2-(2-(2-methoxyethoxy)ethoxy)-
2-(2-(2-methoxyethoxy)ethoxy)ethan-1-ol
2-[2-(2-Methoxy-Ethoxy)-Ethoxy]-Ethoxyl
Methyl Triglycol
Methoxy triglycol
CAS-112-35-6
EINECS 203-962-1
triethyleneglycolmonomethylether
triethylene glycol monomethylether
Triethyleneglycol monomethyl ether
MFCD00002875
Methyl-PEG3-alcohol
METHOXY PEG-3
MPEG-3
EC 203-962-1
PEG-3 METHYL ETHER
3,6,9-trioxadecane-1-ol
PEG-3 MONOMETHYL ETHER
triethyleneglycol monomethylether
MACROGOL 150 METHYL ETHER
PEG-3 METHYL ETHER [INCI]
2-(2-(2-methoxyethoxyl)ethoxy)ethanol
2-(2-(2-Methoxyethoxy);ethoxy);ethanol
2-[2-(2-methoxyethoxy)-ethoxy]-ethanol
Triethylene glycol monomethyl ether, 95%
2-(2'-(2"-methoxy ethoxy)ethoxy)ethanol
CS-0114074
FT-0649849
POLYETHYLENE GLYCOL 150 METHYL ETHER
TRIETHYLENE GLYCOL MONOMETHYL ETHER [HSDB]
J-002758
J-525081
Q27157604
Triethylene glycol monomethyl ether, purum, >=97.0% (GC)
