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MSA 70% (METHANE SULFONIC ACID)

CAS:    75-75-2
MF:    CH4O3S
MW:    96.11
EINECS:    200-898-6

MSA 70% (Methane Sulfonic Acid) is a strong acid widely used as a catalyst (esterification, alkylation, etc.). 
Thanks to its versatility, MSA 70% (Methane Sulfonic Acid) is a viable substitute for organic and inorganic strong acids in a variety of applications. 
MSA 70% (Methane Sulfonic Acid) is a strong organic acid. 
The chemical oxidation of dimetyl sulfide in the atmosphere leads to the formation of MSA 70% (Methane Sulfonic Acid) in large quantities. 
MSA 70% (Methane Sulfonic Acid) undergoes biodegradation by forming CO2 and sulphate.
MSA 70% (Methane Sulfonic Acid) is considered a green acid as it is less toxic and corrosive in comparison to mineral acids.
The aqueous MSA 70% (Methane Sulfonic Acid) has been considered a model electrolyte for electrochemical processes.
MSA 70% (Methane Sulfonic Acid) is an alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl. 
MSA 70% (Methane Sulfonic Acid) has a role as an Escherichia coli metabolite. 
MSA 70% (Methane Sulfonic Acid) is an alkanesulfonic acid and a one-carbon compound. 
MSA 70% (Methane Sulfonic Acid) is a conjugate acid of a methanesulfonate.
MSA 70% (Methane Sulfonic Acid) is a 70% aqueous solution of methanesulfonic acid (MSA). 
MSA 70% (Methane Sulfonic Acid) is a strong organic acid. 
The chemical oxidation of dimetyl sulfide in the atmosphere leads to the formation of MSA in large quantities. 
MSA 70% (Methane Sulfonic Acid) undergoes biodegradation by forming CO2 and sulphate. 
MSA 70% (Methane Sulfonic Acid) is considered a green acid as it is less toxic and corrosive in comparison to mineral acids.
The aqueous MSA 70% (Methane Sulfonic Acid) has been considered a model electrolyte for electrochemical processes.
MSA 70% (Methane Sulfonic Acid) is considered a particularly suitable supporting electrolyte for electrochemical applications, where it stands as an environmentally friendly alternative to other acid electrolytes used in plating processes.
MSA 70% (Methane Sulfonic Acid) is also a primary ingredient in rust remover and descaler. 
MSA 70% (Methane Sulfonic Acid) is recommended in formulation for removing rust from ceramic, tiles and porcelain surfaces which are usually susceptible to acid attack.

MSA 70% (Methane Sulfonic Acid) Chemical Properties
Melting point: 17-19 °C (lit.)
Boiling point: 167 °C/10 mmHg (lit.)
Density: 1.475-1.485 g/mL at 20 °C 1.481 g/mL at 25 °C (lit.)
Vapor density: 3.3 (vs air)
Vapor pressure: 1 mm Hg ( 20 °C)
Refractive index: n20/D 1.429(lit.)
Fp: >230 °F
Storage temp.: 2-8°C
Solubility water: soluble1,000 g/L at 20°C
pka: -2.6(at 25℃)
Form: Solution
Color: brown
Specific Gravity: 1.48 (18/4℃)
Water Solubility: Miscible with water. 
Slightly miscible with benzene and toluene. Immiscible with paraffins.
λmax λ: 240-320 nm Amax: <0.4
Sensitive: Light Sensitive & Hygroscopic
Merck: 14,5954
BRN: 1446024
Stability: Stable. Moisture sensitive. Incompatible with amines, bases, water, common metals. 
Releases a substantial amount of heat when diluted with water (add acid to water with care if diluting).
InChIKey: AFVFQIVMOAPDHO-UHFFFAOYSA-N
CAS DataBase Reference: 75-75-2(CAS DataBase Reference)
NIST Chemistry Reference: CH3SO3H(75-75-2)
EPA Substance Registry System: Methanesulfonic acid (75-75-2)

MSA 70% (Methane Sulfonic Acid) is a colourless or light yellow liquid having a melting point of 20° C, is a strong acid acting corroding but not oxidizing.
MSA 70% (Methane Sulfonic Acid) is used in the electroplating industry and for organic syntheses, in particular as a catalyst for alkylations, esterifications, and polymerizations. 
Beyond that, MSA 70% (Methane Sulfonic Acid) is used as a starting material for the preparation of methanesulfonyl chloride.
MSA 70% (Methane Sulfonic Acid) is a 70% aqueous solution of methane sulfonic acid (MSA). 
MSA 70% (Methane Sulfonic Acid) is a strong organic acid. MSA undergoes biodegradation by forming CO2 and sulphate. 
MSA 70% (Methane Sulfonic Acid) is considered a green acid as it is less toxic and corrosive in comparison to mineral acids. 
The aqueous MSA 70% (Methane Sulfonic Acid) has been considered a model electrolyte for electrochemical processes. 

Uses
MSA 70% (Methane Sulfonic Acid) is used as a catalyst in organic reactions namely esterification, alkylation and condensation reactions due to its non- volatile nature and solubility in organic solvents. 
MSA 70% (Methane Sulfonic Acid) is also involved in the production of starch esters, wax oxidate esters, benzoic acid esters, phenolic esters, or alkyl esters. 
MSA 70% (Methane Sulfonic Acid) reacts with sodium borohydride in presence of polar solvent tetrahydrofuran to prepare borane-tetrahydrofuran complex. 
MSA 70% (Methane Sulfonic Acid) finds application in batteries, because of its purity and chloride absence. 
In pharmaceutical industry, MSA 70% (Methane Sulfonic Acid) is used for the manufacturing of active pharmaceutical ingredients like telmisartan and eprosartan. 
MSA 70% (Methane Sulfonic Acid) is useful in ion chromatography and is a source of carbon and energy for some gram-negative methylotropic bacteria.
MSA 70% (Methane Sulfonic Acid) is involved in the deprotection of peptides.

MSA 70% (Methane Sulfonic Acid)
1-Strong acid
2-Readily Biodegradable & low VOC
3-Non oxidizing and not foaming
4-Compatible with oxidizing agent and biocides
5-High solubility of salts
6-Odorless
7-High thermal stability 

Synonyms
METHANESULFONIC ACID
75-75-2
Methylsulfonic acid
Methanesulphonic acid
Mesylate
Mesylic acid
Kyselina methansulfonova
Sulfomethane
Methansulfonsaeure
NSC 3718
CH3SO3H
MFCD00007518
CHEBI:27376
22515-76-0
MSA
NSC-3718
12EH9M7279
ammoniummethanesulfonate
CCRIS 2783
Kyselina methansulfonova [Czech]
HSDB 5004
EINECS 200-898-6
BRN 1446024
METHANE SULFONIC ACID
AI3-28532
UNII-12EH9M7279
metanesulfonic acid
methansulfonic acid
MsOH
methansulphonic acid
methylsulphonic acid
03S
methyl sulfonic acid
methyl-sulfonic acid
methane-sulfonic acid
MeSO3H
methane sulphonic acid
methanesulphonic-acid-
LACTIC ACID(DL)
ammonium methanesulphonate
CH3SO2OH
H3CSO3H
DSSTox_CID_6422
WLN: WSQ1
EC 200-898-6
DSSTox_RID_78109
Methane Sulfonic Acid 99%
Methanesulfonic acid solution
DSSTox_GSID_26422
4-04-00-00010 (Beilstein Handbook Reference)
Methanesulfonic acid, 99.5%
Methanesulfonic acid, anhydrous
CHEMBL3039600
DL-MALICACIDMONOSODIUMSALT
DTXSID4026422
METHANESULFONIC ACID [II]
METHANESULFONIC ACID [MI]
Methanesulfonic acid, HPLC grade
NSC3718
Methanesulfonic acid, >=99.0%
METHANESULFONIC ACID [HSDB]
Tox21_201073
STL264182
Methane Sulfonic Acid, 70% Solution
AKOS009146947
AT25153
J1.465F
CAS-75-75-2
NCGC00248914-01
NCGC00258626-01
BP-12823
DB-075013
FT-0628287
M0093
M2059
Methanesulfonic acid, >=99.0%, ReagentPlus(R)
Methanesulfonic acid, for HPLC, >=99.5% (T)
A934985
Methanesulfonic acid solution, 70 wt. % in H2O
Q414168
J-521696
Methanesulfonic acid, Vetec(TM) reagent grade, 98%
F1908-0093
Z940713430
Methanesulfonic acid solution, 4 M (with 0.2% (w/v) tryptamine)
Methanesulfonic acid concentrate, 0.1 M CH3SO3H in water (0.1N), eluent concentrate for IC
Methanesulfonic acid, PharmaGrade, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production

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