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EC / List no.: 214-291-9
CAS no.: 1119-97-7
Mol. formula: C17H38N.Br
Myrtrimonium Bromide (Cetrimide) is an antiseptic agent, meaning it has various antibacterial, antifungal and other antimicrobial properties and can be applied to skin or mucous membranes to avoid or minimize the risk of infection.
Myrtrimonium Bromide (Cetrimide) is also a surfactant, meaning it functions as a detergent with cleaning properties.
As a pharmaceutical ingredient, it is used in various products mainly for topical use in sprays, gels and creams for a range of purposes, including cleaning burns and wounds, for disinfecting skin before injections or surgery, and for treating fungal infections or nappy rash.
Myrtrimonium Bromide (Cetrimide) compounds are used in disinfectants and sanitizers to treat swimming pools and industrial water reservoirs, as antiseptics for cleaning wounds, skin, and burns, in hair conditioners, as softeners for textiles and paper, and as pigment dispersers
Myrtrimonium Bromide (Cetrimide) Used as a disinfectant, deodorant, and laboratory reagent.
Formerly registered in the US as a disinfectant and carpet cleaner for institutional, hospital, restaurant, and related applications
Myrtrimonium Bromide (Cetrimide) is an organic molecular entity.
Myrtrimonium Bromide (Cetrimide) compound whose salts and derivatives are used primarily as topical antiseptics.
Physical properties
Myrtrimonium Bromide (Cetrimide) is a white fine powder crystal with a melting point of 245°C to 250°C.
A rough estimate of its density is 1.1328. It is soluble in water with a solubility of 20 g/100 mL.
Description
Myrtrimonium Bromide (Cetrimide) is a dynamin I/II inhibitor targeting the dynamin-phospholipid interaction and inhibiting dynamin GTPase activity with a Ki=940nM.
Rapidly and reversibly inhibits multiple forms of endocytosis with no acute cellular damage.
A useful pharmacological tool for studying dynamin-mediated trafficking events.
Induces cytokinesis failure and apoptosis in human cancer cells.
Induces cytoprotective autophagy in human Jurkat T cells.
Uses:
Disinfectant; deodorant; laboratory reagent.
Myrtrimonium Bromide (Cetrimide) has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure.
Myrtrimonium Bromide (Cetrimide) has also been used in a study to determine the low molecular weight of organic acids in soils and plants by capillary zone electrophoresis.
General Description
Myrtrimonium Bromide (Cetrimide) is a cationic/zwitterionic type of surfactant.
Purification Methods
Crystallise the bromide from acetone or a mixture of Me2CO and >5% MeOH or Me2CO/EtOH.
Wash it with diethyl ether and dry it in a vacuum oven at 60o.
Myrtrimonium Bromide (Cetrimide) is a cationic detergent. Its solubility is 1g/5g H2O.
General Information/ Characteristics:
Myrtrimonium Bromide (Cetrimide) is a quaternary ammonium compound which is a part of a group of ammonium salts that are typically prepared by treatment of an amine and an alkylating agent.
They demonstrate a variety of physical, chemical and biological properties and most are soluble in water as they possess properties of strong electrolytes.
These compounds are additionally known to have the ability to disrupt a micro-organism’s cell processes thus make excellent preservatives.
Benefits / Application: Skin and hair care benefits:
- Acts as an antiseptic and as a detergent thus it is used in the treatment of dandruff, itchy or oily scalp.
- Has been known to treat psoriasis and seborrheic dermatitis of the scalp and skin.
Applications:
- Antimicrobial lotions and skin care soaps.
- Detergents, sanitizers and softeners.
- Pigment dispersal agents.
- 2 in 1 shampoo.
- Hair dressing gels and leave in conditioners.
- Make-up products and make-up removers.
Myrtrimonium Bromide (Cetrimide) is an organic molecular entity.
Myrtrimonium Bromide (Cetrimide) compound whose salts and derivatives are used primarily as topical antiseptics.
Formula: C17H38BrN
Formula Weight: 336.40
Melting point: 245-250°
Storage & Sensitivity: Ambient temperatures.
Solubility: Soluble in water. (100 g/L)
Applications
Myrtrimonium Bromide (Cetrimide) has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure.
Myrtrimonium Bromide (Cetrimide) has also been used in a study to determine the low molecular weight of organic acids in soils and plants by capillary zone electrophoresis.
Myrtrimonium Bromide (Cetrimide)) (TTABr) is an organic building block and cationic surfactant.
Myrtrimonium Bromide (Cetrimide) forms hemimicelles and is used as a surface active aid in capillary separation of acid-derived anionic species.
Myrtrimonium Bromide (Cetrimide) is increasingly used in capillary electrophoresis as a surface active aid in the separation of acid derived anionic species.
Myrtrimonium Bromide (Cetrimide) has been observed that Tetradecyltrimethylammonium bromide requires a minimum concentration of approximately 0.4mM for best results.
This value has been chosen because it is close to its critical micelle concentration (CMC), and it has been projected that this concentration is required for “hemimicelles” to be formed on the inner wall of the capillary
Myrtrimonium Bromide (Cetrimide) is a cationic surfactant that inhibits the activity of bacterial cells via interactions with the Toll-like receptor, a protein that plays an important role in the innate immune system.
This molecule has been shown to have antibacterial efficacy against wild-type and benzalkonium chloride-resistant strains of Staphylococcus aureus.
Myrtrimonium Bromide (Cetrimide) also suppresses the growth of Hl-60 cells by inhibiting DNA polymerase activity.
Myrtrimonium Bromide (Cetrimide) is soluble in water and has a molecular weight of 438.5 g/mol.
Myrtrimonium Bromide (Cetrimide) was synthesized from monoethyl ether and hl-60 cells were used as biological samples to measure its rate constant through electrochemical impedance spectroscopy (EIS).
Myrtrimonium Bromide (Cetrimide) has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure.
Myrtrimonium Bromide (Cetrimide) has also been used in a study to determine the low molecular weight of organic acids in soils and plants by capillary zone electrophoresis.
Myrtrimonium Bromide (Cetrimide) is a cationic surfactant used to improve biomass harvesting and pigment extraction from microalgae.
Microalgae have enormous potential to be sustainable feedstock for numerous bioproducts such as lipids, proteins, carbohydrates, etc.
Used as a disinfectant, deodorant, and laboratory reagent.
Formerly registered in the US as a disinfectant and carpet cleaner for institutional, hospital, restaurant, and related applications
About Myrtrimonium Bromide (Cetrimide)
Helpful information
Myrtrimonium Bromide (Cetrimide) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.
Myrtrimonium Bromide (Cetrimide) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
Myrtrimonium Bromide (Cetrimide) is used in the following products: cosmetics and personal care products, perfumes and fragrances and pharmaceuticals.
Other release to the environment of Myrtrimonium Bromide (Cetrimide) is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Article service life
Other release to the environment of Myrtrimonium Bromide (Cetrimide) is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).
Myrtrimonium Bromide (Cetrimide) can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), paper used for articles with intense direct dermal (skin) contact during normal use such as personal hygiene articles (e.g. nappies, feminine hygiene products, adult incontinence products, tissues, towels, toilet paper) and paper used for articles with intense direct dermal (skin) contact during normal use such as printed articles (e.g. newspapers, books, magazines, printed photographs).
Widespread uses by professional workers
Myrtrimonium Bromide (Cetrimide) is used in the following products: laboratory chemicals and cosmetics and personal care products.
Myrtrimonium Bromide (Cetrimide) is used in the following areas: health services and scientific research and development.
Other release to the environment of Myrtrimonium Bromide (Cetrimide) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Formulation or re-packing
Myrtrimonium Bromide (Cetrimide) is used in the following products: perfumes and fragrances, cosmetics and personal care products, laboratory chemicals, pharmaceuticals and water treatment chemicals.
Release to the environment of Myrtrimonium Bromide (Cetrimide) can occur from industrial use: formulation of mixtures and formulation in materials.
Uses at industrial sites
Myrtrimonium Bromide (Cetrimide) is used in the following products: cosmetics and personal care products.Myrtrimonium Bromide (Cetrimide) is used in the following areas: health services and scientific research and development.
Release to the environment of Myrtrimonium Bromide (Cetrimide) can occur from industrial use: as processing aid.
Manufacture
Release to the environment of Myrtrimonium Bromide (Cetrimide) can occur from industrial use: manufacturing of the substance.
IUPAC NAMES:
(1-Tetradecyl)trimethylammonium bromide
1-Tetradacanaminiumm, N,N,N-trimethyl-, bromide
Cetrimida
CETRIMIDE
Cetrimide
Cetrimide bp
hexadecyl(trimethyl)azanium bromide
Myristyltrimethylammonium bromide
N,N,N-trimethyltetradecan-1-aminium bromide
TETRADECYL-TRIMETHYL-AMMONIUMBROMIDE
Tetradecyltrimethylammonium Bromide
Tetradecyltrimethylammonium bromide
Tetradonium bromide
tetradonium bromide
Tetradonium bromide
tetradonium bromide
Tetradonium bromide [INN]
trimethyl(tetradecyl)azanium bromide
SYNONYMS:
1119-97-7
Cetrimide
Myristyltrimethylammonium bromide
Tetradecyltrimethylammonium bromide
Tetradonium bromide
MITMAB
N,N,N-trimethyltetradecan-1-aminium bromide
Tetradecyl Trimethyl Ammonium Bromide
TTAB
8044-71-1
Myrtrimonium bromide
trimethyl(tetradecyl)azanium;bromide
1-Tetradecanaminium, N,N,N-trimethyl-, bromide
Trimethyltetradecylammonium bromide
trimethyl(tetradecyl)azanium bromide
Trimethyl(tetradecyl)ammonium bromide
MTAB
CHEBI:3565
Mytab
Tetradecyltrimethylammonium (bromide)
8483H94W1E
Morpan T
Quaternium 13
Myrtrimonium bromide;Cetrimide BP; MTAB; Microcide II; Morpan T;
Alkyltrimethylammonium bromide
CHEMBL113150
Tetradonio bromuro
Tetradonio bromuro [DCIT]
Tetradonium bromide [INN]
Tetradonii bromidum
CAS-1119-97-7
Ammonium, trimethyltetradecyl-, bromide
Bromuro de tetradonio
Trimethylmyristylammonium bromide
Bromure de tetradonium
Tetradonii bromidum [INN-Latin]
EINECS 214-291-9
Bromure de tetradonium [INN-French]
Bromuro de tetradonio [INN-Spanish]
Quammonium
N,N,N-Trimethyl-1-tetradecanaminium bromide
Cetrimide bromide
Myristyl trimethyl ammonium bromide
Cetrimide (JAN
N-Tetradecyltrimethylammonium bromide
(1-TETRADECYL)TRIMETHYLAMMONIUM BROMIDE
AMMONIUM, TETRADECYLTRIMETHYL-, BROMIDE
Myristyltrimethylaminium bromide
1-Tetradecanaminium, N,N,N-trimethyl-, bromide (1:1)
Tetradecyltrimethylammmonium bromide
Trimethyltetradecyl Ammonium Bromide
N,N,N-trimethyltetradecan-1-aminiumbromide
(1-Tetradecyl)trimethylammonium bromide, 98%
UNII-24QSH2NL8N component CXRFDZFCGOPDTD-UHFFFAOYSA-M
alkyl*trimethylammoniumbromide*(c14,5%c16)
alkyltrimethylammoniumbromide
alkyltrimethylammoniumbromide(c14,5%c16)
Tetradecanaminium,N,N,N-trimethyl-,bromide
tetradecyltrimethyl-ammoniubromide
MYRTRIMONIUM BROMIDE
(1-Tetradecyl)trimethylammonium bromide
TETRADECYLTRIMETHYLAMMONIUM BROMIDE, FOR IPC
MicrocideIitm
MyristylTrimethylAmoniumBromide
Trimethyl-N-tetradecylammoniumbromide
MTAB
1-Tetradecanaminium, N,N,N-trimethyl-, bromide
TETRADECYLTRIMETHYLAMMONIUMBROMIDE,REAGENT
Tetradoniumbromid
Cetrimide
Myristyltrimethylammonium bromide
Tetradecyl trimethyl ammonium bromide
Tetradecyltrimethylammonium bromide
MYRISTYL (TETRADECYL) TRIMETHYL AMMONIUM BROMIDE
TETRADECYLTRIMETHYLAMMOUNIUM BROMIDE
CETRIMIDE extrapure AR
Tetradecyltrimethylammonium bromide, Trimethyl(tetradecyl)ammonium bromide
Myristyltrimethylammonium bromide ,98%
Tetradecyltrimethylaminium·bromide
Myristyltrimethylaminium·bromide
morpant
mytab
n,n,n-trimethyl-1-tetradecanaminiubromide
N,N,N-Trimethyl-1-tetradecanaminumbromide
quaternium13
N, N, N- triMethyl-1-tetradecyl broMide
Myristyltrimethylammonium bromide 98% (AT)
Myristyltrimethylammonium bromide Vetec(TM) reagent grade, >=99%
Dynamin Inhibitor II, MiTMAB - CAS 1119-97-7 - Calbiochem
TTAB
TRIMETHYLMYRISTYLAMMONIUM BROMIDE
TRIMETHYL-TETRADECYLAMMONIUM BROMIDE
tetradonium
tetradoniumbromide
trimethyltetradecyl-ammoniubromide
N,N,N-TRIMETHYL-1-TETRADECANAMINIUM BROMIDE
N-TETRADECYL-N,N,N-TRIMETHYLAMMONIUM BROMIDE
(N-TETRADECYL)TRIMETHYLAMMONIUM BROMIDE
Dynamin Inhibitor II, MiTMAB
Tetradecyltrimethylammonium bromide for synthesis
Dynamin Inhibitor II
Tetradonium brom
[M3C14N]Br
Trimethyltetradecylaminium·bromide
Myristyltrimethylammonium bromide,99%
Tetradecyltrimethylammonium bromide, HPLC grade
Myristyltrimethylammonium bromide,Tetradecyltrimethylammonium bromide, Trimethyl(tetradecyl)ammonium bromide
Myristyltrimethylamm
Myristyltrimethylammonium bromide purum, >=98.0% (AT)
MitMAB
N,N,N-TriMethyl-1-tetradecaneaMMoniuM broMide
1432
