N-CHLORO-P-TOLUENESULFONAMIDE

N-chloro-p-toluenesulfonamide is an organic chlorine compound with an available chlorine content of 28 to 30%
N-chloro-p-toluenesulfonamide is a conjugate acid of a chloro(p-tolylsulfonyl)azanide.
N-chloro-p-toluenesulfonamide is used as a mild disinfectant. 

CAS NUMBER: 144-86-5

EC NUMBER: -

MOLECULAR FORMULA: C7H8ClNO2S

MOLECULAR WEIGHT: 205.66

IUPAC NAME: N-chloro-4-methylbenzenesulfonamide

N-chloro-p-toluenesulfonamide is intended for use in fish farming for prevention and control of bacterial gill disease.
N-chloro-p-toluenesulfonamide is toluene-p-sulfonamide chlorinated at nitrogen. 

N-chloro-p-toluenesulfonamide is functionally related to a toluene-4-sulfonamide. 
N-chloro-p-toluenesulfonamide is also known as chloramine-T
N-chloro-p-toluenesulfonamide is a chlorinated and deprotonated sulfonamide 

N-chloro-p-toluenesulfonamide is not stable in the water dissolved form.
N-chloro-p-toluenesulfonamide is a versatile reagent in organic synthesis and analytical chemistry

N-chloro-p-toluenesulfonamide is a low-cost mild oxidizing agent
N-chloro-p-toluenesulfonamide has a wide range of uses. 

Most importantly, N-chloro-p-toluenesulfonamide can be used in acidic, neutral, and basic conditions. 
N-chloro-p-toluenesulfonamide’s been widely used in chemistry, particularly in organic synthesis and analytical chemistry. 

N-chloro-p-toluenesulfonamide acts as a source of halonium cation and nitrogen anion 
N-chloro-p-toluenesulfonamide acts as base and nucleophile. 

N-chloro-p-toluenesulfonamide reacts with a wide range of functional groups
N-chloro-p-toluenesulfonamide carries different molecular transformations. 

N-chloro-p-toluenesulfonamide is a salt of sodium. 
N-chloro-p-toluenesulfonamide has multiple applications, such as fungicide, algicide, bacteriacide, virucide, and germicide

N-chloro-p-toluenesulfonamide is specially used for chlorination in drinking water treatment 
N-chloro-p-toluenesulfonamide contains electrophilic chlorine as well as more electronegative nitrogen.

N-chloro-p-toluenesulfonamide is also being used in medical, dental and veterinary, food processing, and agriculture because of its anti-microbial property
N-chloro-p-toluenesulfonamide is also the primary disinfectant along with chlorine, chloramines, chlorine dioxide, and potassium permanganate in many areas such as kitchens, laboratories, and hospitals

N-chloro-p-toluenesulfonamide is also effective in treating columnar diseases and monogenean trematodes.
N-chloro-p-toluenesulfonamide is specially used for chlorination in drinking water treatment

N-chloro-p-toluenesulfonamide is used in destruction of toxins
N-chloro-p-toluenesulfonamide can be used in degradation of biofilms, and anticoagulated and anti-inflammatory activities. 

N-chloro-p-toluenesulfonamide destroys the activities of pathogens by the process of oxidative stress cascade
N-chloro-p-toluenesulfonamide is also known as sodium N-chloro-4methylbenzenesulfonamide

N-chloro-p-toluenesulfonamide is a byproduct of saccharin fabrication. 
N-chloro-p-toluenesulfonamide is cheap, easy to handle

N-chloro-p-toluenesulfonamide is sodium salt, sold as chloramine-T
N-chloro-p-toluenesulfonamide is a N-chlorinated and N-deprotonated sulfonamide

N-chloro-p-toluenesulfonamide is used as a biocide and a mild disinfectant. 
N-chloro-p-toluenesulfonamide is a white powder that gives unstable solutions with water. 

USES: 
Iodination and radioiodination:
N-chloro-p-toluenesulfonamide acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl). 
N-chloro-p-toluenesulfonamide is widely used for the incorporation of iodine to peptides and proteins. 
N-chloro-p-toluenesulfonamide together with iodogen or lactoperoxidase is commonly used for labeling peptides and proteins with radioiodine isotopes (123I, 125I or 131I).

Biocide:
N-chloro-p-toluenesulfonamide is available in tablet or powder form and has to be dissolved before use. 

N-chloro-p-toluenesulfonamide used in areas such as hospitals, laboratories, nursing homes, funeral homes, medical, dental and veterinary facilities, where control of pathogens is required, for disinfecting surfaces and soaking medical and dental equipment. 
N-chloro-p-toluenesulfonamide is also used for parasite control and for drinking water disinfection.

N-chloro-p-toluenesulfonamide is as an algicide, bactericide, virucide, fungicide (including spores), germicide. 
N-chloro-p-toluenesulfonamide is also effective against mycobacteria such as tuberculosis, foot-and-mouth disease and avian influenza. 
The molecular structure of N-chloro-p-toluenesulfonamide is similar to para-aminobenzoic acid, an intermediate in bacterial metabolism, which is disrupted by this sulfonamide (in the same way as by a sulfa drug). 
Therefore, N-chloro-p-toluenesulfonamide is capable of inhibiting with bacterial growth with two mechanisms, with the phenylsulfonamide moiety and the hypochlorite, which destroys the DNA structure via oxidation and thereby prevents microbes from reproducing and reforming.

Protective Agent:
N-chloro-p-toluenesulfonamide reacts readily with mustard gas to yield a harmless crystalline sulfimide
N-chloro-p-toluenesulfonamide is used as protective agents against poison gas.

PHYSICAL PROPERTIES: 

-Molecular Weight: 205.66    

-XLogP3-AA: 1.7        

-Exact Mass: 204.9964274    

-Monoisotopic Mass: 204.9964274    

-Topological Polar Surface Area: 54.6 Ų

-Physical Description: White or slightly yellow crystals or crystalline powder

-Color: White or slightly yellow

-Form: Solid

-Odor: Slight odor of chlorine

-Melting Point: 170-177 °C

-Flash Point: 192 °C

-Solubility: Soluble in water

-Density: 1.4 g/cm³

-Chemical Classes: Other Uses -> Biocides/Disinfectants

N-chloro-p-toluenesulfonamide is toluene-p-sulfonamide chlorinated at nitrogen. 
N-chloro-p-toluenesulfonamide is also known as chloramine-T

N-chloro-p-toluenesulfonamide is a chlorinated and deprotonated sulfonamide 
N-chloro-p-toluenesulfonamide is a low-cost mild oxidizing agent

CHEMICAL PROPERTIES: 

-Hydrogen Bond Donor Count: 1    

-Hydrogen Bond Acceptor Count: 3    

-Rotatable Bond Count: 2

-Heavy Atom Count: 12    

-Formal Charge: 0    

-Complexity: 226    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 1    

-Compound Is Canonicalized: Yes

N-chloro-p-toluenesulfonamide acts as a source of halonium cation and nitrogen anion 
N-chloro-p-toluenesulfonamide reacts with a wide range of functional groups

N-chloro-p-toluenesulfonamide is a salt of sodium. 
N-chloro-p-toluenesulfonamide is also the primary disinfectant along with chlorine, chloramines, chlorine dioxide, and potassium permanganate in many areas such as kitchens, laboratories, and hospitals

N-chloro-p-toluenesulfonamide is used in destruction of toxins
N-chloro-p-toluenesulfonamide can be used in anticoagulated and anti-inflammatory activities. 

N-chloro-p-toluenesulfonamide is also known as sodium N-chloro-4methylbenzenesulfonamide
N-chloro-p-toluenesulfonamide is sodium salt

N-chloro-p-toluenesulfonamide is used as a mild disinfectant. 
N-chloro-p-toluenesulfonamide is a white powder

N-chloro-p-toluenesulfonamide is used as protective agents against poison gas.
N-chloro-p-toluenesulfonamide acts as an effective oxidizing agent

N-chloro-p-toluenesulfonamide is widely used for the incorporation of iodine
N-chloro-p-toluenesulfonamide used in areas such as hospitals, laboratories, nursing homes, funeral homes, medical, dental and veterinary facilities, where control of pathogens is required, for disinfecting surfaces and soaking medical and dental equipment. 
N-chloro-p-toluenesulfonamide is also used for drinking water disinfection.

SYNONYMS: 

N-Chloro-p-toluenesulfonamide
N-chloro-4-methylbenzenesulfonamide
tosylchloramide
144-86-5
Benzenesulfonamide, N-chloro-4-methyl-
N-chlorotoluene-p-sulfonamide
N-chloro-4-methylbenzene-1-sulfonamide
p-Toluenesulfonamide, N-chloro-
n-chloro-4-methyl-benzenesulfonamide
N-Chloro-4-Toluenesulfonamide, Sodium salt
EN300-215534
N-chloro 4-methylbenzenesulfonamide, sodium salt
N-chloro para-toluenesulfonylamide,
sodium chloro[(4-methyl phenyl)sulfonyl]azanide, chloramine-T
Chloramine-T
CHLORAMINE T
127-65-1
Chloralone
Chlorasan
Chlorozone
Tosylchloramide sodium
Acti-chlore
Chloraseptine
Chlorazone
Chlorseptol
Multichlor
Tochlorine
Aktivin
Chlorazan
Chlorosol
Heliogen
Mannolite
Tampules
Tolamine
Sodium chloramine T
Chlorina Aktivin
Monochloramine T
Sodium chloro(tosyl)amide
Sodium tosylchloramide
Sodium p-toluenesulfonchloramide
Chlorazene
Tosilcloramida sodica
Tosylchloramide sodique
Tosylchloramidum natricum
Berkendyl
Clorina
Euclorina
Anexol
(N-Chloro-p-toluenesulfonamido)sodium
Sodium p-toluenesulfonylchloramide
Cloramine T
N-Chloro-p-toluenesulfonamide sodium
Sodium N-chloro-p-toluenesulfonamide
Gyneclorina
Clorosan
Halamid
Mianine
Gansil
Chloramin Heyden
Kloramine-T
Tosylchloramide sodium
N-Chlorotoluenesulfonamide sodium salt
N-Chloro-4-methylbenzylsulfonamide sodium salt
sodium chloro(4-methylbenzenesulfonyl)azanide
328AS34YM6
[chloro(p-tolylsulfonyl)amino]sodium
Aseptoclean
Desinfect
Tosylchloramid-natrium
149358-73-6
Tosylchloramide sodium (INN)
chloramine-T anhydrous
Benzenesulfonamide, N-chloro-4-methyl-, sodium salt (1:1)
Chloramine-t
p-Toluenesulfonchloramide Sodium Salt
N-Chloro-p-toluenesulfonamide sodium salt
EINECS 204-854-7
Tosilcloramida sodica
N-Chloro-4-methylbenzenesulfonamide sodium salt
Tosylchloramide sodique
Tosylchloramidum natricum
Chloramin T
p-Toluenesulfonamide, N-chloro-, sodium salt
Sodiumchloro(tosyl)amide
CHLORAMINE-T
TOSYLCHLORAMIDE SODIUM
sodium;chloro-(4-methylphenyl)sulfonylazanide
TOSYLCHLORAMIDE SODIUM
EN300-75322
sodium chloro[(4-methylphenyl)sulfonyl]azanide
Chloramine (T) N-Chloro-4-toluenesulfonamide,sodium salt