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N-DODECANOIC ACID

CAS NUMBER: 143-07-7

EC NUMBER:  205-582-1

MOLECULAR FORMULA: C12H24O2

MOLECULAR WEEGHT: 200.32

 


DESCRIPTION:

N-Dodecanoic acid is a white needle-like crystal at room temperature, with a slight fragrance of laurel oil. 
N-Dodecanoic acid is insoluble in water, soluble in methanol, ether, chloroform and other organic solvents, slightly soluble in acetone and petroleum ether.

N-Dodecanoic acid is a white solid with a slight odor of bay oil.
N-Dodecanoic acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. 

N-Dodecanoic acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
N-Dodecanoic acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids. 

N-Dodecanoic acid is a bright white, powdery solid with a faint odor of bay oil or soap. 
The salts and esters of N-Dodecanoic acid are known as laurates.

N-Dodecanoic acid comprises about half of the fatty-acid content in coconut milk, coconut oil, laurel oil, and palm kernel oil (not to be confused with palm oil).
Otherwise, N-Dodecanoic acid is relatively uncommon. 

Like many other fatty acids, N-Dodecanoic acid is inexpensive, has a long shelf-life, is nontoxic, and is safe to handle. 
N-Dodecanoic acid is used mainly for the production of soaps and cosmetics. 

For these purposes, N-Dodecanoic acid is reacted with sodium hydroxide to give sodium laurate, which is a soap. 
Most commonly, N-Dodecanoic acid is obtained by saponification of various oils, such as coconut oil. 

These precursors give mixtures of N-Dodecanoic acid and other soaps.
N-Dodecanoic acid is a precursor to dilauroyl peroxide, a common initiator of polymerizations.

N-Dodecanoic acid increases total serum lipoproteins more than many other fatty acids, but mostly high-density lipoprotein (HDL). 
As a result, N-Dodecanoic acid has been characterized as having "a more favorable effect on total HDL than any other fatty acid, either saturated or unsaturated".

N-Dodecanoic acid is a saturated medium-chain fatty acid with a 12-carbon backbone. 
N-Dodecanoic acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.

N-Dodecanoic acid is a saturated medium-chain fatty acid with a 12-carbon backbone. 
N-Dodecanoic acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.

N-Dodecanoic acid belongs to the class of organic compounds known as medium-chain fatty acids. 
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. 

N-Dodecanoic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. 
N-Dodecanoic acid is a potentially toxic compound.

N-Dodecanoic acid has been used as a reagent to synthesize MnFe2O4 magnetic nanoparticles by seed mediated growth method. 
N-Dodecanoic acid can undergo esterification with 2-ethylhexanol in the presence of sulfated zirconia catalyst to form 2-ethylhexanoldodecanoate, a biodiesel.

N-Dodecanoic acid is a saturated fatty acid, which is found in animal and plant fats and oils, and is a major component of coconut oil and palm kernel oil. 
N-Dodecanoic acid has potential antimicrobial property, and can be used in soaps and shampoos manufacturing. 

N-Dodecanoic acid is ideal as a standard and for biological studies. 
During the metabolism of dodecanoic acid it is converted to the omega-hydroxy dodecanoic acid and then to the dicarboxylic dodecanedioc acid. 

In some marine organisms dodecanoic acid is hydroxylated in other positions as well as at the terminal position.
N-Dodecanoic acid is a saturated medium-chain fatty acid with a 12-carbon backbone. 

N-Dodecanoic acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
N-Dodecanoic acid is a solid waxy white substance with a weak characteristic acid odour. 

The melting point is 44 °C and it’s thermally stable at room temperature. 
The vapour pressure is determined to 0.0012 Pa at 25 °C. 

N-Dodecanoic acid shows a very low solubility in water at 20 °C with a typical solubility profile. 
Only weak temperature dependence was determined. 

Because of the formation of micelles at pH > 7, the solubility is determined at pH-values 3, 5 and in an un-buffered system. 
N-Dodecanoic acid is one of the specialists in the sales of N-Dodecanoic acid in Europe. 

N-Dodecanoic acid or dodecanoic acid is a medium-chain saturated fatty acid, that contains 12 carbon atoms (C 12) without any double bonds. 
N-Dodecanoic acid is very present in coconut oil. 

N-Dodecanoic acid is also found in breast milk, in which it is the main fatty acid.
N-Dodecanoic acid is a saturated fatty acid since there is no double bond in the aliphatic chain, so in shorthand is named 12:0. 

N-Dodecanoic acid is a member of the sub-group called medium chain fatty acids or MCFA, namely fatty acids containing from 6 to 12 carbon atoms.
N-Dodecanoic acid is found in high amount in some tropical oils.

N-Dodecanoic acid is present in high quantity in coconut oil and palm kernel oil, approximately 45 g/100 g edible portion.
N-Dodecanoic acid should be noted that palm kernel oil is extracted from the seeds of oil palms, while palm oil from the pulp of the fruit of oil palms.

In the other vegetable fats and oils, tropical or not, such as extra virgin olive oil, corn oil, palm oil, soy oil, sesame oil, margarine, peanut butter, and so on, it is absent or present in low amount (e.g., margarine, 0.76 g/100 g edible portion).
N-Dodecanoic acid is also virtually absent in the fat of red and white meat, eggs, and fish products. 

Small amounts are found in the lard, 0.23 g, and smoked eel, 0.28/g/100 g edible portion.
N-Dodecanoic acid is present in low concentrations, <2.5 g/100 g edible portion, in milk and dairy products.

N-Dodecanoic acid is abundant only in coconut, both fresh and dried, with respectively 16 g and 29 g/100 g edible portion. 
N-Dodecanoic acid is not present in the other fruit.

N-Dodecanoic acid is not found in cereals and legumes.
N-Dodecanoic acid is a saturated carboxylic acid with the molecular formula C12H24O2 and the linear formula:CH3-(CH2)10-COOH0. 

N-Dodecanoic acid is derived from the alkane n-dodecane.
N-Dodecanoic acid occurs naturally as glycerol ester in coconut oil and in laurel oil, as well as cetyl ester in spermaceti.

N-Dodecanoic acid has a melting point at 43.7ºC and a boiling point at 227ºC. 
N-Dodecanoic acid is soluble in ether and ethanol, insoluble in water.

N-Dodecanoic acid is mainly used for the production of soaps and cosmetics. 
N-Dodecanoic acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap.

N-Dodecanoic acid is a powerful substance that’s sometimes extracted from the coconut for use in developing monolaurin.
N-Dodecanoic acid is a saturated fatty acid. 

N-Dodecanoic acid's molecular formula is C12H24O2. 
Although N-Dodecanoic acid is called lauric acid, it only contains 1-3% oil. 

Today, high-acid vegetable oils N-Dodecanoic acid are coconut oil (45-52%), palm kernel oil (44-52%) and babassu kernel oil (43-44%).
Although N-Dodecanoic acid is a saturated fatty acid, its cardiovascular risk is lower than other saturated fatty acids.

N-Dodecanoic acid is a saturated fatty acid with a 12-carbon atom chain. 
The powdery, white crystalline acid has a slight odor of oil of bay and occurs naturally in various plant and animal fats and oils. 

N-Dodecanoic acid is a major component of coconut oil and palm kernel oil. 
N-Dodecanoic acid is mainly used in the manufacturing of soaps and other cosmetics.

In scientific laboratories, N-Dodecanoic acid is often used to investigate the molar mass of unknown substances via freezing-point depression. 
In industry, N-Dodecanoic acid is used as an intermediate and as a surface active agent. 

The consumer market uses N-Dodecanoic acid in the cleaning, furnishing, and production of personal care products. 
In medicine, lauric acid is known to increase total serum cholesterol more than many of the other fatty acids.

N-Dodecanoic acid is produced as a white crystalline powder, has a slight odor of bay oil, and is soluble in water, alcohols, phenyls, haloalkanes, and acetates. 
N-Dodecanoic acid is non-toxic, safe to handle, inexpensive, and has a long shelf life. 

N-Dodecanoic acid is mainly used in the manufacture and production of soaps and other cosmetics as well as scientific laboratory uses.
N-Dodecanoic acid is a medium-length long-chain fatty acid, or lipid, that makes up about half of the fatty acids within coconut oil. 

N-Dodecanoic acid’s a powerful substance that is sometimes extracted from the coconut for use in developing monolaurin. 
N-Dodecanoic acid is an antimicrobial agent that is able to fight bacteria, viruses, yeasts, and other pathogens. 

Like many other fatty acids, N-Dodecanoic acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle. 
N-Dodecanoic acid is mainly used for the production of soaps and cosmetics. 

For these purposes,N-Dodecanoic acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap. 
N-Dodecanoic acid is a common constituent of vegetable fats, especially coconut oil and laurel oil. 

N-Dodecanoic acid may have a synergistic effect in a formula to help fight against mircoorganisms. 
N-Dodecanoic acid is a mild irritant but not a sensitizer, and some sources cite it as comedogenic.

N-Dodecanoic acid is a fatty acid obtained from coconut oil and other veg- etable fats. 
N-Dodecanoic acid is practically insoluble in water but is soluble in alco- hol, chloroform, and ether. 
N-Dodecanoic acid functions as a lubricant, binder, and defoaming agent.

 

APPLICATION:

For the preparation of alkyd resins and wetting agents, detergents and pesticides.
N-Dodecanoic acid can be used for peeling vegetables and fruits, and the maximum usage is 3.0g/kg.

N-Dodecanoic acid is allowed to be used as a spice.
N-Dodecanoic acid is a component for preparing other food-grade additives.

N-Dodecanoic acid is the most widely used in the surfactant industry. 
N-Dodecanoic acid is a 100% natural material used by the cosmetic industry (hair care, skin care), detergency, and many other applications. 

N-Dodecanoic acid is an emulsifying agent, also used as a cleaning agent or as a surfactant. 
N-Dodecanoic acid sells it in solid form.

 

COSMETIC USES:

-cleansing agents
-surfactants
-surfactant - emulsifying

 

PROPERTIES:

-Acid value mgKOH/g: 278.0 282.0
-Iodine Value % Max: 0.5% Max.
-Titer Deg °C: 43.0 44.0
-Colour Lovibond 5 1/4″: 0.2 R Max.- 1 Y Max.
-Water Content % Max.: 0.2 % Max.
-Unsap Matter % Max.: 0.5 % Max.
-Acid value mgKOH/g: 278.0 282.0
-Ionization mode: Positive
-logIE: 0.42
-pH: 2.7
-Instrument: Agilent XCT
-Ion source: Electrospray ionization
-Additive: formic acid (5.3nM)
-Appearance: white needle-like crystals

 

CHEMICAL PROPERTIES:

-Quality Level: 200
-assay: 98%
-bp: 225 °C/100 mmHg (lit.)
-mp: 44-46 °C (lit.)
-density: 0.883 g/mL at 25 °C (lit.)

 

FIRST AID MEASURES:

-Inhalation: 

Move to fresh air. 
Call a physician if symptoms develop or persist.


-Skin contact: 

Remove contaminated clothing. 
Wash with plenty of soap and water. 
If skin irritation occurs: Get medical advice/attention. 
Wash contaminated clothing before reuse.


-Eye contact: 

Immediately flush eyes with plenty of water for at least 15 minutes. 
Remove contact lenses, if present and easy to do. 
Continue rinsing. 
Get medical attention immediately.
Ingestion Rinse mouth. 
Get medical attention if symptoms occur.

 


DEFINITION:

N-Dodecanoic acid is a saturated fat. 
N-Dodecanoic acid is found in many vegetable fats, particularly in coconut and palm kernel oils. 

People use N-Dodecanoic acid as medicine.
N-Dodecanoic acid is used for treating viral infections including influenza (the flu); swine flu; avian flu; the common cold; fever blisters, cold sores, and genital herpes caused by herpes simplex virus (HSV); genital warts caused by human papillomavirus (HPV); and HIV/AIDS. 

N-Dodecanoic acid is also used for preventing the transmission of HIV from mothers to children.
Other uses for N-Dodecanoic acid include treatment of bronchitis, gonorrhea, yeast infections, chlamydia, intestinal infections caused by a parasite called Giardia lamblia, and ringworm.

N-Dodecanoic acid is used as a vegetable shortening.
N-Dodecanoic acid is used to make soap and shampoo.

 

CHARACTERISTICS:

-PSA: 37.3
-XLogP3: 4.2
-Appearance: White Crystalline Powder of Flakes
-Density: 0.883 g/cm3 @ Temp: 20 °C
-Melting Point: 44.2 °C
-Boiling Point: 298.9 °C
-Flash Point: >230 °F
-Refractive Index: 1.4304
-Water Solubility: H2O: insoluble
-Storage Conditions: Store below +30°C.
-Vapor Pressure: 1 mm Hg ( 121 °C)
-Toxicity: LD50 i.v. in mice: 131 ±5.7 mg/kg (Or, Wretlind)
-Explosive limit: 0.6%(V)
-Odor: Characteristic, like oil of bay
-PKA: 5.3(at 20 °C)

 

COMPUTED PROPERTIES:

-Molecular Weight: 200.32
-XLogP3: 4.2
-Hydrogen Bond Donor Count: 1
-Hydrogen Bond Acceptor Count: 2
-Rotatable Bond Count: 10
-Exact Mass: 200.177630004
-Monoisotopic Mass: 200.177630004
-Topological Polar Surface Area: 37.3
-Heavy Atom Count: 14
-Complexity: 132
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes

 

USES:

N-Dodecanoic acid is used for peeling vegetables and fruits with a maximum amount of 3.0g/kg.
N-Dodecanoic acid is used as defoamer; GB 2760-86 provides for the spices allowed to use; used for the preparation of other food grade additives.

N-Dodecanoic acid is widely used in the surfactant industry and can be, according to the classification of surfactants, divided into cationic, anionic, non-ionic and amphoteric type. 
The surfactants types of dodecanoic acid are listed in the attached table of this item. 

Some surfactants of the derivatives of dodecanoic acid and dodecanol are also antiseptics, such as dodecyl dimethyl benzyl ammonium chloride (geramine), dodecyl dimethyl benzyl ammonium bromide (bromo-geramine) and dodecyl dimethyl (2-phenoxyethyl) ammonium bromide (domiphen bromide). 
N-Dodecanoic acid can be used as citrus preservative. 
N-Dodecanoic acid has many applications in plastic additives, food additives, spices and pharmaceutical industries.

 


HOW DOES IT WORK:

N-Dodecanoic acid is not known how lauric acid might work as a medicine. 
Some research suggests N-Dodecanoic acid might be a safer fat than trans-fats in food preparations.

 

SPECIFICATION:

-Source: natural
-Purity: 99%
-Analytical Methods: GC, TLC
-Natural Source: plant
-Solubility: chloroform, ethanol, ethyl ether
-Physical Appearance: solid

 

FUNCTION:

N-Dodecanoic acid is used in many applications, including: Anionic and nonionic surfactants, and raw materials for emulsifiers. 
N-Dodecanoic acid is used in the rubber industry as an activator/accelerator/plasticizer and softener. 
N-Dodecanoic acid is widely used in pharmaceuticals, surfactants, soaps, detergents, cosmetics, daily chemicals.

 

STORAGE:

Store in a cool, ventilated and dry place to prevent sun and rain.
Keep away from heat source and fire, keep away from moisture and sunshine.

 

SYNONYM:

lauric acid
143-07-7
n-Dodecanoic acid
Dodecylic acid
Laurostearic acid
Vulvic acid
Dodecoic acid
Duodecylic acid
1-Undecanecarboxylic acid
Aliphat No. 4
Neo-fat 12
Neo-fat 12-43
C12 fatty acid
Ninol AA62 Extra
Wecoline 1295
Hydrofol acid 1255
Hydrofol acid 1295
Duodecyclic acid
Hystrene 9512
DodecylcarboxylateUnivol U-314
Lauric acid, pure
Lauric acid (natural)
Coconut oil fatty acids
ABL
Undecane-1-carboxylic acid
NSC-5026
FEMA No. 2614
Laurinsaeure
C12:0
C-1297
n-Dodecanoate
Philacid 1200
Dodecanoic Acid Anion
CHEBI:30805
Prifrac 2920
Lunac L 70
Emery 651
MFCD00002736
DAO
CH3-[CH2]10-COOH
NSC5026
1160N9NU9U
dodecylate
laurostearate
vulvate
DODECANOIC ACID (LAURIC ACID)
DSSTox_CID_1590
1-undecanecarboxylate
DSSTox_RID_76223
DSSTox_GSID_21590
CAS-143-07-7
SMR001253907
CCRIS 669
HSDB 6814
EINECS 205-582-1
BRN 1099477
dodecanic acid
lauric-acid
UNII-1160N9NU9U
Acide Laurique
AI3-0011
n-Dodecanoicacid
Lauric acid (NF)
Lauric Acid 652
DODECANOICACID
Kortacid 1299
Lauric Acid, Reagent
Nissan NAA 122
Emery 650
Lunac L 98
Prifac 2920
Univol U 314
Dodecanoic acid, 98%
Dodecanoic acid, 99%
Dodecanoic (Lauric) acid
LAURIC ACID 
bmse000509
LAURIC ACID 
EC 205-582-1
LAURIC ACID 
LAURIC ACID 
SCHEMBL5895
NCIOpen2_009480
4-02-00-01082 (Beilstein Handbook Reference)
MLS002177807
MLS002415737
WLN: QV11
Dodecanoic acid (lauric acid)
LAURIC ACID
LAURIC ACID 
Dodecanoic acid, >=99.5%
Edenor C 1298-100
DODECANOIC ACID [HSDB]
CHEMBL108766
GTPL5534
Lauric acid-1,2-[13C2]
DTXSID5021590
Lauric acid-1,12-[13C2]
HMS2268C14
HMS3649N06
HY-Y0366
STR08039
ZINC1529498
Dodecanoic acid, analytical standard
Lauric acid, >=98%, FCC, FG
Tox21_202149
Tox21_303010
BDBM50180948
LMFA01010012
s4726
STL281860
AKOS000277433
Lauric acid-1,2,3,4-[13C4]
CCG-266587
DB03017
NCGC00090919-01
NCGC00090919-02
NCGC00090919-03
NCGC00256486-01
NCGC00259698-01
AC-16451
BP-27913
Dodecanoic acid, >=99% 
LAU
Dodecanoic acid, purum, >=96.0% (GC)
Lauric acid, natural, >=98%, FCC, FG
CS-0015078
FT-0625572
FT-0695772
L0011
A16350
C02679
D10714
A808010
Q422627
SR-01000838338
J-007739
SR-01000838338-3
F0001-0507
LAURIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC]
Z966690584
76C2A2EB-E8BA-40A6-8032-40A98625ED7B
dodecanoic acid
lauric acid
lauric acid, ammonium salt
lauric acid, barium and cadmium salt (4:1:1)
lauric acid, calcium salt
lauric acid, lithium salt
lauric acid, magnesium salt
lauric acid, nickel(2+) salt
lauric acid, potassium salt
lauric acid, sodium salt
1-Undecanecarboxylate
1-Undecanecarboxylic acid
ABL
Acide Laurique
C12 fatty acid
C12:0
Coconut oil fatty acids
DAO
Dodecanoate
dodecanoic acid
dodecoate
Dodecoic acid
Dodecylate
dodecylcarboxylate
Dodecylic acid
duodecyclate
Duodecyclic acid
duodecylate
Duodecylic acid
LAP
LAU
Laurate
Lauric acid
Laurinsaeure
Laurostearate
Laurostearic acid
MYR
n-Dodecanoate
n-Dodecanoic acid
Sorbitan laurate
Sorbitan monolaurate (NF)
undecane-1-carboxylate
Undecane-1-carboxylic acid
Vulvate
Vulvic acid
CH3-[CH2]10-COOH
Dodecylcarboxylic acid
Laate
Laic acid
Aliphat no. 4
Edenor C 1298-100
Emery 651
Hystrene 9512
Kortacid 1299
Lunac L 70
Lunac L 98
Neo-fat 12
Neo-fat 12-43
Nissan naa 122
Philacid 1200
Prifac 2920
Univol u 314
1-Dodecanoic acid

 

 

 

 

 

 

 

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