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N,N'-METHYLENE-BIS-ACRYLAMIDE

N,N'-Methylene-bis-acrylamide is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel.
N,N'-Methylene-bis-acrylamide is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.
N,N'-Methylene-bis-acrylamide is a chemical compound with the molecular formula C7H10N2O2.

CAS Number: 110-26-9
Molecular Formula: C7H10N2O2
Molecular Weight: 154.17
EINECS Number: 203-750-9

N,N'-METHYLENEBISACRYLAMIDE, 110-26-9, N,N'-Methylenediacrylamide, N,N'-Methylene-bis-acrylamide, Methylenebisacrylamide, Bis-acrylamide, Methylenediacrylamide, n,n-methylenebisacrylamide, N,N'-Methylenebis(acrylamide), Bisacrylamide, 2-Propenamide, N,N'-methylenebis-, N-[(prop-2-enoylamino)methyl]prop-2-enamide, N,N'-Methylidenebisacrylamide, Acrylamide, N,N'-methylenebis-, N,N'-Methylenebis(2-propenamide), NSC 406836, MBAA, N-[(prop-2-enamido)methyl]prop-2-enamide, EDK4RIE19C, N,N'-methylene bisacrylamide, MLS001055454, DTXSID8025595, MFCD00008625, NSC-406836, Bisacrylamide; MBA;Methylenebisacrylamide, NCGC00090721-03, SMR001227199, Acrylamide, N'-methylenebis-, N,N'-Methylenebis[acrylamide], 2-Propenamide, N'-methylenebis-, bis acrylamide, CCRIS 4672, EINECS 203-750-9, UNII-EDK4RIE19C, N-((PROP-2-ENOYLAMINO)METHYL)PROP-2-ENAMIDE, BRN 1706297, AI3-08643, NAPP, Methylenebis[acrylamide], cid_8041, n,n'-methylenebis acrylamide, n,n'-methylenebis-acrylamide, SCHEMBL20000, N-(acrylamidomethyl)acrylamide, N,N' methylene bis acrylamide, N,N`-Methylene-bis-acrylamide, DTXCID205595, N,N'-Diacryloylmethylenediamine, CHEMBL1401480, N,N'-Methylidenebis[acrylamide], BDBM74235, NSC7774, HY-D0848, N,N'-Methylenebis-Acrylamide, 2%, NSC-7774, Tox21_400038, NSC406836, AKOS005206740, AKOS025264600, N,N'-Methylenebis(acrylamide), 99%, N-[(Acryloylamino)methyl]acrylamide #, METHYLENEBIS-ACRYLAMIDE, N,N'-, NCGC00090721-01, NCGC00090721-02, NCGC00090721-04, CAS-110-26-9, NCI60_041713, N,N'-METHYLENEBISACRYLAMIDE [INCI], N,N'-Methylenebisacrylamide, p.a., 98%, N,N'-Methylenebis(acrylamide), >=99.0%, BB 0295285, CS-0014818, CS-0202692, FT-0629399, M0506, M2877, E80374, EN300-104853, A905227, N-[(1-oxoprop-2-enylamino)methyl]-2-propenamide, Q3869308, W-108692, N,N'-Methylenebis(acrylamide), Vetec(TM) reagent grade, Bis-acrylamide, Molecular biology and electrophoresis grade, N,N'-Methylenebisacrylamide, for molecular biology, >=98%, N,N'-Methylenebisacrylamide, powder, for molecular biology, for electrophoresis, >=99.5%, N,N'-Methylenebisacrylamide,for electrophoresis, Y99.0%(T), 26949-19-9, N,N'-Methylenebisacrylamide, suitable for electrophoresis (after filtration or allowing insolubles to settle).

N,N'-Methylene-bis-acrylamide is commonly used in polymer chemistry as a crosslinking agent or crosslinker.
N,N'-Methylene-bis-acrylamide contains two acrylamide groups connected by a methylene bridge.
As a symmetric, unconjugated divinyl monomer, N,N'-Methylene-bis-acrylamide can be used with suitable initiators in cyclopolymerizations to create linear, soluble polymers whose backbones are built from five- and seven-membered rings.

With acrylic and vinylic monomers such as acrylonitrile, acrylamide, and substituted acrylamides, N,N'-Methylene-bis-acrylamide can undergo radical copolymerization to form highly crosslinked gels, using peroxides, UV light, or redox initiators.
The properties of such gels are determined by the crosslink density, and targeted gel formation using N,N'-Methylene-bis-acrylamide crosslinking gives useful technical properties used in various applications, such as in adhesives, paints, and superabsorbents.
In biochemistry, N,N'-Methylene-bis-acrylamide is used for chromatography gels and polyacrylamide gel electrophoresis.

N,N'-Methylene-bis-acrylamide is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel.
N,N'-Methylene-bis-acrylamide is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.
N,N'-Methylene-bis-acrylamide is the organic compound with the formula CH2[NHC(O)CH=CH2]2.

N,N'-Methylene-bis-acrylamide a colorless solid, this compound is a crosslinking agent in polyacrylamides, e.g., as used for SDS-PAGE.
N,N'-Methylene-bis-acrylamide is a cross linking agent that readily polymerizes with acrylamide to create cross links within the polyacrylamide gel matrix.
N,N'-Methylene-bis-acrylamide effectively creates a network rather than linear chains, a property that helps in maintaining the firmness of gel.

N,N'-Methylene-bis-acrylamide is widely used in gel preparation and also as a test compound for studying the biochemical isolation of insoluble Tau protein in transgenic mouse models of tauopathy.
N,N'-Methylene-bis-acrylamide is a cross-linking agent used during the formation of polymers such as polyacrylamide.
N,N'-Methylene-bis-acrylamide is molecular formula is C7H10N2O2.

N,N'-Methylene-bis-acrylamide is used in the preparation of polyacrylamide gels for electrophoretic separation of nucleic acids and proteins.
Recommended for use with N,N'-Methylene-bis-acrylamide Solution, 40% (sc-3721).
Acrylamide forms linear polymers and bis-Acrylamide introduces cross-links between polyacrylamide chains; by mixing the appropriate ratio of Acrylamide to N,N'-Methylene-bis-acrylamide, the optimal pore size can be obtained for the protein being resolved.

Ready-to-use N,N'-Methylene-bis-acrylamide solutions offer convenience and eliminate the risks associated with the handling of acrylamide powder.
Polymerization agents, TEMED (sc-29111) and APS (Ammonium persulfate, sc-202946) are also available.
N,N'-Methylene-bis-acrylamide is a cross-linker reagent used for precise, critical PAGE gels.

N,N'-Methylene-bis-acrylamide may be used in UV scanning gels.
N,N'-Methylene-bis-acrylamide should mixed with acrylamide for making polyacrylamide gels for use in protein and nucleic acid electrophoresis.
N,N′-Methylenebisacrylamide has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.

N,N′-Methylenebisacrylamide, also known as N,n'-methylene-bis(acrylamide), belongs to the class of organic compounds known as acrylic acids and derivatives.
These are organic compounds containing acrylic acid CH2=CHCO2H or a derivative thereof.
Based on a literature review a significant number of articles have been published on N,N′-Methylenebisacrylamide.

N,N'-Methylene-bis-acrylamide has been identified in human blood as reported by (PMID: 31557052).
N,N'-Methylene-bis-acrylamide is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives.
Technically N,N'-Methylene-bis-acrylamide is part of the human exposome.

The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health.
An individual's exposure begins before birth and includes insults from environmental and occupational sources.
N,N′-Methylenebisacrylamide is a cross linking agent that readily polymerizes with acrylamide to create cross links within the polyacrylamide gel matrix.

N,N'-Methylene-bis-acrylamide effectively creates a network rather than linear chains, a property that helps in maintaining the firmness of gel.
N,N'-Methylene-bis-acrylamide is widely used in gel preparation and also as a test compound for studying the biochemical isolation of insoluble Tau protein in transgenic mouse models of tauopathy.
N,N'-Methylene-bis-acrylamide, also called Bisacrylamide, is a crosslinking agent commonly used for the formation of polymers such as polyacrylamide gels.

N,N'-Methylene-bis-acrylamide is essential in the preparation of protein electrophoresis gels, such as those used in SDS-PAGE.
Visit the supplier page for more product information, such as purity and reagent grade.
N,N'-Methylene-bis-acrylamide is used in the preparation of poly-acrylamides.

N,N'-Methylene-bis-acrylamide is also used in preparing poly-acrylamide gel for electrophoresis and chemical grouting.
Further research may identify additional product or industrial usages of this chemical.
N,N'-Methylene-bis-acrylamide is a white crystalline powder with a neutral odor.

N,N'-Methylene-bis-acrylamide is primarily used as a crosslinking agent in the polymerization of certain monomers.
N,N'-Methylene-bis-acrylamide facilitates the formation of crosslinks between polymer chains, enhancing the mechanical strength and stability of the resulting polymer.
N,N'-Methylene-bis-acrylamide is commonly employed in the preparation of polyacrylamide gels.

These gels are used in techniques such as gel electrophoresis for the separation of biomolecules like proteins and nucleic acids.
In the presence of N,N'-Methylene-bis-acrylamide, acrylamide monomers undergo polymerization, forming a three-dimensional network structure.
The degree of crosslinking can be adjusted to achieve specific properties in the final polymer.

N,N'-Methylene-bis-acrylamide is used in the gel casting process to create polyacrylamide gels for applications in various scientific fields, including molecular biology and biochemistry.
N,N'-Methylene-bis-acrylamide gels crosslinked with MBAm are utilized in biomedical research for applications such as protein separation and DNA analysis.
Acrylamide and its derivatives, including N,N'-Methylene-bis-acrylamide, are generally considered toxic.

Proper safety precautions, including the use of personal protective equipment (PPE), should be taken when handling these substances.
Compliance with safety regulations and guidelines is essential when working with N,N'-Methylene-bis-acrylamide.
This includes proper storage, handling, and disposal practices.

Due to concerns about the toxicity of acrylamide compounds, there is ongoing research in green chemistry to develop alternative crosslinkers with reduced environmental and health risks.
Researchers are exploring bio-based and environmentally friendly alternatives to traditional crosslinkers like N,N'-Methylene-bis-acrylamide.
The concentration of MBAm and reaction conditions can be adjusted to control the degree of crosslinking and tailor the properties of the resulting polymer.

The use of N,N'-Methylene-bis-acrylamide influences the physical and chemical properties of the polymer, including its mechanical strength, porosity, and thermal stability.
Users should refer to the Safety Data Sheet provided by the manufacturer for specific information regarding the hazards, safe handling practices, and emergency procedures associated with N,N'-Methylene-bis-acrylamide.
N,N'-Methylene-bis-acrylamide, belongs to the class of organic compounds known as acrylic acids and derivatives.

These are organic compounds containing acrylic acid CH2=CHCO2H or a derivative thereof. Based on a literature review a significant number of articles have been published on N,N'-Methylene-bis-acrylamide.
N,N'-Methylene-bis-acrylamide has been identified in human blood as reported by (PMID: 31557052 ).
N,N'-Methylene-bis-acrylamide is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives.

Technically N,N'-Methylene-bis-acrylamide is part of the human exposome.
The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health.
An individual's exposure begins before birth and includes insults from environmental and occupational sources.

N,N'-Methylene-bis-acrylamide, 2% (bis-Acrylamide) is used in the preparation of polyacrylamide gels for electrophoretic separation of nucleic acids and proteins.
Recommended for use with Acrylamide Solution, 40% (sc-3721). Acrylamide forms linear polymers.
N,N'-Methylene-bis-acrylamide acts as a crosslinking agent by forming covalent bonds between polymer chains during the polymerization process.

This three-dimensional network enhances the structural integrity of the polymer.
In gel casting or gel electrophoresis applications, N,N'-Methylene-bis-acrylamide promotes the formation of a gel matrix that serves as a medium for separating and analyzing biomolecules.
Polyacrylamide gels crosslinked with N,N'-Methylene-bis-acrylamide are commonly used in protein electrophoresis, allowing for the separation of proteins based on their size and charge.

N,N'-Methylene-bis-acrylamide is also utilized in DNA and RNA electrophoresis, aiding in the separation and analysis of nucleic acid fragments.
Polyacrylamide gels prepared with N,N'-Methylene-bis-acrylamide are often employed in Western blotting techniques for the detection of specific proteins in biological samples.
In some applications, N,N'-Methylene-bis-acrylamide-crosslinked gels may play a role in DNA sequencing methodologies.

N,N'-Methylene-bis-acrylamide can be used in the synthesis of hydrogels, which find applications in drug delivery, tissue engineering, and other biomedical fields.
The properties of N,N'-Methylene-bis-acrylamide-crosslinked polymers can be tailored to create responsive materials, such as smart gels that undergo reversible changes in response to external stimuli.
In certain industrial applications, N,N'-Methylene-bis-acrylamide may be utilized in the formulation of adhesives and coatings where crosslinking properties are desired.

Crosslinking agents like N,N'-Methylene-bis-acrylamide can be employed in the textile industry to enhance the properties of fabrics, such as improving their strength and resistance.
The toxicity of acrylamide compounds, including N,N'-Methylene-bis-acrylamide, necessitates careful handling and adherence to safety protocols.
Users should be aware of potential health risks and take appropriate precautions.

Compliance with regulatory standards and guidelines is crucial when working with N,N'-Methylene-bis-acrylamide to ensure the safety of both workers and the environment.
Ongoing research aims to develop biocompatible crosslinkers as alternatives to N,N'-Methylene-bis-acrylamide, especially in applications where minimizing toxicity is a priority.
Advancements in polymer chemistry explore new materials and formulations, aiming for improved performance and reduced environmental impact.

Proper disposal of waste containing MBAm is essential to prevent environmental contamination.
Considerations for eco-friendly disposal methods are relevant.
Future developments may focus on the incorporation of N,N'-Methylene-bis-acrylamide into formulations of biodegradable polymers, aligning with sustainability goals.

Functionalization methods may be explored to introduce specific properties into N,N'-Methylene-bis-acrylamide-crosslinked polymers, expanding their potential applications.
Educational resources and training programs help inform scientists, researchers, and industry professionals about the proper use and safety considerations associated with MBAm.

Melting point: >300 °C(lit.)
Boiling point: 277.52°C (rough estimate)
Density: 1.235
vapor density: 5.31 (vs air)
vapor pressure: 0-0.073Pa at 20-84.85℃
refractive index: 1.4880 (estimate)
storage temp.: 2-8°C
solubility: H2O: 20 mg/mL at 20 °C, clear, colorless
form: powder
pka: 13.07±0.46(Predicted)
color: White
PH: >=5.0 (25g/l, H2O, 20℃)
Odor: Odorless
PH Range: >5
Water Solubility: 0.01-0.1 g/100 mL at 18 ºC
Sensitive: Air & Light Sensitive
λmax: 528nm(H2O)(lit.)
BRN: 1706297
Stability: Light Sensitive
InChIKey: ZIUHHBKFKCYYJD-UHFFFAOYSA-N
LogP: -1.52--0.08 at 24-25℃ and pH4-10

Recrystallise the amide from MeOH (100g dissolved in 500mL boiling MeOH) and filter without suction in a warmed funnel.
Allow to stand at room temperature and then at -15oC overnight.
The crystals are collected with suction in a cooled funnel and washed with cold MeOH.

The crystals are air-dried in a warm oven.
The reaction proceeds via N,N'-Methylene-bis-acrylamide, which can be detected in alkaline solution and decomposes in acid to give N,N'-Methylene-bis-acrylamide.
Using acrylamide and paraformaldehyde in 1,2-dichloroethane gives a clear solution upon heating, from which MBA crystallizes.

In aqueous media, acrylonitrile also reacts with formaldehyde to give crude N,N'-Methylene-bis-acrylamide, which can be purified by recrystallization with acetone/water.
N,N'-Methylene-bis-acrylamide is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel.
N,N'-Methylene-bis-acrylamide is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.

N,N'-Methylene-bis-acrylamide has the molecular formula C7H10N2O2 and features two acrylamide groups linked by a methylene bridge.
The methylene bridge in N,N'-Methylene-bis-acrylamide facilitates the formation of covalent bonds during polymerization, leading to the creation of a crosslinked network.
The polymerization reaction involving N,N'-Methylene-bis-acrylamide often requires specific conditions, including temperature, pH, and the presence of initiators.

The transition from laboratory-scale to industrial-scale production of MBAm and N,N'-Methylene-bis-acrylamide-crosslinked polymers may pose challenges related to scalability and process optimization.
Advancements in continuous manufacturing processes for polymers and hydrogels involving N,N'-Methylene-bis-acrylamide are explored for increased efficiency.
N,N'-Methylene-bis-acrylamide-crosslinked polymers can undergo surface modifications to impart specific functionalities, such as enhanced adhesion or compatibility with other materials.

Modification of surfaces with N,N'-Methylene-bis-acrylamide-crosslinked layers is investigated for applications in biointerfaces, improving interactions with biological systems.
N,N'-Methylene-bis-acrylamide-crosslinked polymers are considered for use in 3D printing materials, offering possibilities for creating complex structures with controlled properties.
N,N'-Methylene-bis-acrylamide into electroactive polymers is explored for applications in sensors, actuators, and electronic devices.

Computational techniques, such as molecular dynamics simulations, are used to model the behavior of N,N'-Methylene-bis-acrylamide-crosslinked polymers at the molecular level.
The development of predictive models aids in understanding the structural and mechanical properties of MBAm-based materials under different conditions.
Adjusting the concentration of N,N'-Methylene-bis-acrylamide in polymerization reactions allows for tuning the crosslinking density, influencing the final properties of the polymer.

Crosslinking with N,N'-Methylene-bis-acrylamide enhances the mechanical strength of polymers, making them suitable for applications requiring durability.
Collaborative efforts between polymer scientists, materials engineers, and researchers from various disciplines contribute to a holistic understanding of MBAm-based materials.
Scientific journals in materials science regularly publish research articles and reviews on the synthesis, properties, and applications of MBAm-crosslinked polymers.

Researchers are exploring the biodegradability of N,N'-Methylene-bis-acrylamide-based materials to align with sustainable practices and reduce environmental impact.
The development of green synthesis routes for N,N'-Methylene-bis-acrylamide or eco-friendly alternatives contributes to sustainable manufacturing practices.
Academic resources, textbooks, and courses cover the principles of polymer chemistry and the use of crosslinkers like N,N'-Methylene-bis-acrylamide, aiding students and researchers in the field.

Access to online databases and repositories provides a wealth of information on the synthesis protocols, properties, and applications of N,N'-Methylene-bis-acrylamide.
Ongoing research explores the integration of N,N'-Methylene-bis-acrylamide into smart materials with responsive and adaptive properties.
Advancements in precision polymer design involve tailoring the structure and properties of polymers crosslinked with N,N'-Methylene-bis-acrylamide for specific applications.

N,N'-Methylene-bis-acrylamide is used in the production of super absorbent resin.
Superabsorbent resin can be used to produce sanitary products with excellent water absorption.
N,N'-Methylene-bis-acrylamide can also be used in the production of agricultural water retaining agent.

In this paper, potato starch and acrylamide were hydrolyzed with methylene bisacrylamide as crosslinking agent to obtain super absorbent resin.
The thickener for all water phase pigment printing is produced by copolymerization of the product with acrylamide and butyl acrylate, which is the key auxiliary for implementing the new process of all water phase pigment printing.
N,N'-Methylene-bis-acrylamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

N,N'-Methylene-bis-acrylamide-crosslinked hydrogels are investigated for drug delivery applications.
These hydrogels can provide controlled release of drugs, making them suitable for various therapeutic purposes.
N,N'-Methylene-bis-acrylamide may be used to create hydrogels that enhance the bioavailability of certain drugs, improving their efficacy and therapeutic outcomes.

N,N'-Methylene-bis-acrylamide-crosslinked polymers are employed in tissue engineering as scaffolds.
These scaffolds provide a structural framework for cell growth and tissue regeneration.
Hydrogels formed with N,N'-Methylene-bis-acrylamide are explored for cell encapsulation, a technique used in tissue engineering to protect and deliver cells to specific sites for regeneration.

N,N'-Methylene-bis-acrylamide is used in the creation of temperature-sensitive hydrogels.
These materials undergo reversible phase transitions in response to temperature changes, making them suitable for various applications.
Responsive materials crosslinked with MBAm can exhibit "smart" behavior, responding to environmental cues such as pH, temperature, or the presence of specific ions.

N,N'-Methylene-bis-acrylamide-crosslinked hydrogels are explored for encapsulating nanoparticles, providing a controlled and stable environment for the delivery of nanoparticles in various fields, including medicine and catalysis.
The crosslinking properties of MBAm contribute to the enhanced stability of nanoparticles within hydrogel matrices.
N,N'-Methylene-bis-acrylamide-crosslinked polymers can be used for enzyme immobilization, a process employed in catalysis and biocatalysis for the stabilization and reuse of enzymes.

N,N'-Methylene-bis-acrylamide-crosslinked polymers are investigated for use in biocompatible implants.
These materials may find applications in medical devices and implants with reduced toxicity concerns.
N,N'-Methylene-bis-acrylamide-crosslinked hydrogels can be explored as matrices for contrast agents in medical imaging applications, providing improved imaging capabilities.

Ongoing efforts in green chemistry aim to develop eco-friendly alternatives to traditional crosslinkers like N,N'-Methylene-bis-acrylamide, focusing on sustainability and reduced environmental impact.
Research explores the use of renewable and bio-based resources in the synthesis of crosslinkers, aligning with the principles of green and sustainable chemistry.

N,N'-Methylene-bis-acrylamide-crosslinked nanocomposite materials are studied for their unique properties, including enhanced mechanical strength and thermal stability.
The incorporation of functional nanoparticles into N,N'-Methylene-bis-acrylamide-crosslinked polymers expands their potential applications in fields such as electronics and sensors.

Uses Of N,N'-Methylene-bis-acrylamide:
N,N'-Methylene-bis-acrylamide is an organic intermediate; cross-linking agent for preparation of polyacrylamides; in preparing poly-acrylamide gel for e1ectrophoresis, chemical grouting and other purposes; in NAPP and Nyloprint UV-cured printing plates.
N,N'-Methylene-bis-acrylamide has been used in gel preparation.
N,N'-Methylene-bis-acrylamide has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.

Cross-linking agent for preparation of N,N'-Methylene-bis-acrylamides.
N,N'-Methylene-bis-acrylamide is used in the preparation of polyacrylamide gels for electrophoretic separation of nucleic acids and proteins.
N,N'-Methylene-bis-acrylamide has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.

N,N'-Methylene-bis-acrylamide is used as an organic intermediate, cross-linking agent, for making polyacrylamides, and for preparing polyacrylamide gel for electrophoresis, chemical grouting.
May cause skin and eye irritation and symptoms indicative of nervous system effects; [NTP] May cause irritation; Harmful by ingestion and inhalation; May cause reproductive disorders, based on animal studies.
N,N'-Methylene-bis-acrylamide is used as photosensitive nylon and photosensitive plastic raw materials, building grouting materials, also used in photography, printing, plate making, etc; N,N'-Methylene-bis-acrylamide can be used as an efficient crosslinking agent in the polymerization of acrylic acid and acrylamide.

N,N'-Methylene-bis-acrylamide is an oil field fracturing fluid, super absorbent resin, water plugging agent, concrete additive, alcohol soluble photosensitive nylon resin, paper.
An important additive in the synthesis of strong agent and water treatment flocculant.
N,N'-Methylene-bis-acrylamide has an industrial application as a crosslinking agent to increase the quality of naturally occurring fibres by graft copolymerization.

Butler and Ingley however found that divinyl monomer can occasionally yield soluble, gel free polymers and they suggested a new type of alternating intra-inter molecular propagation for such cases.
N,N'-Methylene-bis-acrylamide is used as an organic intermediate, cross-linking agent, for making polyacrylamides, and for preparing polyacrylamide gel for electrophoresis, chemical grouting.
N,N'-Methylene-bis-acrylamide is used in the following products: polymers.

N,N'-Methylene-bis-acrylamide is used in the following areas: scientific research and development.
Other release to the environment of N,N'-Methylene-bis-acrylamide is likely to occur from: indoor use as reactive substance.
Release to the environment of N,N'-Methylene-bis-acrylamide can occur from industrial use: formulation of mixtures.

N,N'-Methylene-bis-acrylamide is used in the following products: laboratory chemicals and polymers.
N,N'-Methylene-bis-acrylamide is used in the following areas: scientific research and development.
N,N'-Methylene-bis-acrylamide is used for the manufacture of: chemicals and plastic products.

Release to the environment of N,N'-Methylene-bis-acrylamide can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture and as processing aid.
N,N'-Methylene-bis-acrylamide has been used in gel preparation.
N,N'-Methylene-bis-acrylamide has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.

N,N'-Methylene-bis-acrylamide is a cross-linker reagent used for precise, critical PAGE gels.
N,N'-Methylene-bis-acrylamide, may be used in UV scanning gels.
N,N'-Methylene-bis-acrylamide should mixed with acrylamide for making polyacrylamide gels for use in protein and nucleic acid electrophoresis.

N,N'-Methylene-bis-acrylamide has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.
N,N'-Methylene-bis-acrylamide is used as photosensitive nylon and photosensitive plastic raw materials, building grouting materials, also used in photography, printing, plate making, etc; It can be used as an efficient crosslinking agent in the polymerization of acrylic acid and acrylamide.

N,N'-Methylene-bis-acrylamide may be incorporated into formulations for adhesives and sealants, where its crosslinking properties contribute to the strength and durability of the final product.
In the petroleum industry, N,N'-Methylene-bis-acrylamide-crosslinked polymers are investigated for use in enhanced oil recovery processes and wastewater treatment.
N,N'-Methylene-bis-acrylamide can be utilized in coatings for paper and textiles, enhancing their properties such as strength and resistance to wear.

N,N'-Methylene-bis-acrylamide-crosslinked polymers are explored for membrane fabrication in applications such as water purification and separation processes.
N,N'-Methylene-bis-acrylamide may find applications in the field of dentistry for the development of dental materials, including those used in prosthodontics and restorative dentistry.
N,N'-Methylene-bis-acrylamide can be used in photopolymerization processes, contributing to the creation of photo-crosslinked materials with applications in optical devices and coatings.

N,N'-Methylene-bis-acrylamide-crosslinked matrices are investigated as supports for catalysts in various chemical processes, contributing to catalytic efficiency and stability.
N,N'-Methylene-bis-acrylamide-crosslinked hydrogels may be employed in the development of biosensors for detecting specific biomolecules, contributing to medical diagnostics.
N,N'-Methylene-bis-acrylamide-based coatings that respond to external stimuli, such as changes in pH or temperature, are explored for applications in controlled release systems and sensors.

N,N'-Methylene-bis-acrylamide-crosslinked materials are studied for their potential use in anti-fouling coatings, preventing the adhesion of unwanted substances on surfaces.
In the food and beverage industry, N,N'-Methylene-bis-acrylamide may find applications in certain processes, such as the development of coatings or materials for food packaging.
N,N'-Methylene-bis-acrylamide-crosslinked materials may be incorporated into electrochemical devices, contributing to the development of sensors, batteries, and capacitors.

N,N'-Methylene-bis-acrylamide-crosslinked hydrogels are explored for wound healing applications, providing a supportive environment for tissue regeneration.
N,N'-Methylene-bis-acrylamide-crosslinked polymers are investigated for use in photonic applications, including the development of materials with optical and light-manipulating properties.
Due to its ability to enhance mechanical strength and stability, N,N'-Methylene-bis-acrylamide contributes to the development of high-performance materials used in various industries.

N,N'-Methylene-bis-acrylamide is used in the following products: polymers.
N,N'-Methylene-bis-acrylamide is used in the following areas: scientific research and development.
Other release to the environment of N,N'-Methylene-bis-acrylamide is likely to occur from: indoor use as reactive substance.

Release to the environment of N,N'-Methylene-bis-acrylamide can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture and as processing aid.
N,N'-Methylene-bis-acrylamide is commonly used in the preparation of polyacrylamide gels for gel electrophoresis.
This technique is widely used for the separation of biomolecules such as proteins and nucleic acids based on their size and charge.

In biochemistry and molecular biology, N,N'-Methylene-bis-acrylamide is utilized for protein electrophoresis.
N,N'-Methylene-bis-acrylamide helps create polyacrylamide gels that serve as a matrix for separating proteins based on their molecular weight.
N,N'-Methylene-bis-acrylamide-crosslinked gels are also employed in the electrophoretic separation of nucleic acids (DNA and RNA), facilitating the analysis and purification of genetic material.

N,N'-Methylene-bis-acrylamide is used in the synthesis of hydrogels. These hydrogels have applications in drug delivery, tissue engineering, and as matrices for controlled release of substances.
In tissue engineering, N,N'-Methylene-bis-acrylamide-crosslinked polymers are employed as scaffolds.
These scaffolds provide a three-dimensional structure for cell growth and tissue regeneration.

Hydrogels formed with N,N'-Methylene-bis-acrylamide are investigated for drug delivery applications.
The crosslinked structure allows for controlled and sustained release of pharmaceutical agents.
N,N'-Methylene-bis-acrylamide is used in various biomedical research applications, including the development of biomaterials, implants, and devices.

N,N'-Methylene-bis-acrylamide-crosslinked polymers can exhibit responsive behavior to external stimuli such as temperature, pH, or the presence of specific ions.
These materials find applications in smart devices and sensors.
N,N'-Methylene-bis-acrylamide is explored for use in 3D printing materials, contributing to the fabrication of complex structures with tailored properties.

Safety Profile Of N,N'-Methylene-bis-acrylamide:
N,N'-Methylene-bis-acrylamide dust or vapors can lead to respiratory irritation.
Adequate ventilation and respiratory protection are recommended.
Direct contact with MBAm may cause skin irritation and dermatitis.

Prolonged or repeated exposure can result in sensitization.
N,N'-Methylene-bis-acrylamide can cause eye irritation. Eye protection, such as safety goggles or a face shield, is recommended.
N,N'-Methylene-bis-acrylamide can lead to gastrointestinal irritation and may pose systemic health risks.

Ingestion should be avoided, and immediate medical attention is required in case of accidental ingestion.
Chronic exposure to acrylamide compounds, including N,N'-Methylene-bis-acrylamide, may have neurotoxic effects, affecting the central and peripheral nervous systems.
There are concerns about the potential reproductive and developmental toxicity of acrylamide compounds.