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N,N-DIETHYLETHANOLAMINE

CAS:    100-37-8
MF:    C6H15NO
MW:    117.19
EINECS:    202-845-2

N,N-Diethylethanolamine is a colorless liquid. 
Flash point 103-140°F. 
N,N-Diethylethanolamine is less dense than water. 
Vapors heavier than air. 
Produces toxic oxides of nitrogen during combustion. 
Causes burns to the skin, eyes and mucous membranes.
N,N-Diethylethanolamine is an aminoalcohol. 
Amines are chemical bases. 
They neutralize acids to form salts plus water. 
These acid-base reactions are exothermic. 

The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. 
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. 
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. 
N,N-Diethylethanolamine can react with strong oxidizers and acids.
N,N-Diethylethanolamine is a member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups. 
N,N-Diethylethanolamine is a member of ethanolamines, a tertiary amino compound and a primary alcohol. 
N,N-Diethylethanolamine derives from an ethanolamine. 

N,N-Diethylethanolamine derives from a hydride of a triethylamine.
N,N-Diethylethanolamine is a chemical compound with the molecular formula C6H15NO. 
N,N-Diethylethanolamine is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine. 
N,N-Diethylethanolamine can be reacted with 4-aminobenzoic acid to make procaine. 
N,N-Diethylethanolamine can be used as a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography. 
N,N-Diethylethanolamine can also be conveniently obtained from renewable sources. 
N,N-Diethylethanolamine is chemically stable and able to absorb carbon dioxide (CO2) from its surroundings. 
In solution, N,N-Diethylethanolamine can decrease the surface tension of water when the temperature is increased.

N,N-Diethylethanolamine is a chemical compound with the molecular formula C6H15NO. 
N,N-Diethylethanolamine is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine. 
N,N-Diethylethanolamine can be reacted with 4-aminobenzoic acid to make procaine. 
N,N-Diethylethanolamine can be used as a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography. 
N,N-Diethylethanolamine can also be conveniently obtained from renewable sources. 
N,N-Diethylethanolamine is chemically stable and able to absorb carbon dioxide (CO2) from its surroundings. 
In solution, N,N-Diethylethanolamine can decrease the surface tension of water when the temperature is increased.
N,N-Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.
N,N-Diethylethanolamine is an irritant to the eyes, skin, and respiratory system.
The Occupational Safety and Health Administration and the National Institute for Occupational Safety and Health have set occupational exposure limits for workers handling the chemical at 10 ppm (50 mg/m3) over an eight-hour workday.
N,N-Diethylethanolamine is difficult or insoluble in non-polar solvents such as aliphatic hydrocarbons and the like.
An azeotrope may be formed with water. Hygroscopic, placed in the air can absorb carbon dioxide. 
N,N-Diethylethanolamine is easy to change color in long-term storage or temperature environment at 40 °c. 
Flammable, fire, high-energy combustion caused by explosion. 
Reactions with strong oxidants can cause combustion, the products of which are carbon monoxide, carbon dioxide and nitrogen oxides.

N,N-Diethylethanolamine Chemical Properties
Melting point: -70 °C
Boiling point: 161 °C (lit.)
Density: 0.884 g/mL at 25 °C (lit.)
Vapor density: 4.04 (vs air)
Vapor pressure: 1 mm Hg ( 20 °C)
Refractive index: n20/D 1.441(lit.)
Fp: 120 °F
Storage temp.: Store below +30°C.
Solubility: soluble
Form: Crystalline Powder
pka: 14.74±0.10(Predicted)
Color: White to pale yellow
PH Range: 10
PH: 11.5 (100g/l, H2O, 20℃)
Explosive limit: 0.7%(V)
Water Solubility: soluble
FreezingPoint: -70℃
Merck: 14,3112
BRN: 741863
Exposure limits: NIOSH REL: TWA 10 ppm (50 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 10 ppm; ACGIH TLV: TWA 2 ppm (adopted).
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, acids. Moisture sensitive. Hygroscopic.
InChIKey: BFSVOASYOCHEOV-UHFFFAOYSA-N
LogP: 0.21 at 23℃
CAS DataBase Reference: 100-37-8(CAS DataBase Reference)
NIST Chemistry Reference: N,N-Diethylethanolamine (100-37-8)
EPA Substance Registry System: N,N-Diethylethanolamine (100-37-8)

Colorless liquid with a nauseating, weak, ammonia odor; hygroscopic; very soluble in water; soluble in alcohol, ether acetone, benzene, and petroleum ether.
Colorless, hygroscopic liquid with a nauseating, ammonia-like odor. 
Experimentally determined detection and recognition odor threshold concentrations were 50 μg/m3 (11 ppbv) and 190 μg/m3 (40 ppbv), respectively.

Uses    
N,N-Diethylethanolamine can be used as a precursor chemical to procaine. 
N,N-Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen. 
N,N-Diethylethanolamine is used for the synthesis of drugs in the pharmaceutical industry and as a catalyst for the synthesis of polymers in the chemical industry. 
N,N-Diethylethanolamine is also used as a pH stabilizer.
N,N-Diethylethanolamine is used in the pharmaceutical industry for the manufacture of the local anesthetics procaine and chloroquine; and in the chemical industry for the manufacture of water-soluble salts, fatty-acid derivatives, derivatives containing tertiary amine groups, emulsifiers, special soaps, cosmetics and textiles and fibers. 

N,N-Diethylethanolamine also is used in chromatography in chemistry and biochemistry laboratories (N,N-Diethylethanolamine is useful as an ion-exchange matrix; DEAE-cellulose columns are used for purification of proteins and DNA, and DEAE-silica for phospholipid separations). 
In other industries N,N-Diethylethanolamine is used in some antirust compositions and in textile softeners (Hawley 1977; HSDB 1988). 
N,N-Diethylethanolamine is also used widely as a steam additive in large buildings requiring humidifiers.
N,N-Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.
N,N-Diethylethanolamine is used in the following products: lubricants and greases, metal working fluids, coating products, hydraulic fluids and laboratory chemicals. 
N,N-Diethylethanolamine is used in the following areas: building & construction work. 

N,N-Diethylethanolamine is used for the manufacture of: fabricated metal products and . 
Other release to the environment of N,N-Diethylethanolamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Preparation
N,N-Diethylethanolamine is prepared commercially by the reaction of diethylamine and ethylene oxide.
(C2H5)2NH + cyclo(CH2CH2)O → (C2H5)2NCH2CH2OH
N,N-Diethylethanolamine is also possible to prepare it by the reaction of diethylamine and ethylene chlorohydrin.

Synonyms
2-(Diethylamino)ethanol
2-Diethylaminoethanol
DIETHYLAMINOETHANOL
100-37-8
N,N-Diethylethanolamine
Diethylethanolamine
DEAE
(Diethylamino)ethanol
Ethanol, 2-(diethylamino)-
N,N-Diethyl-2-aminoethanol
(2-Hydroxyethyl)diethylamine
Diethyl(2-hydroxyethyl)amine
Diethylmonoethanolamine
2-Hydroxytriethylamine
Pennad 150
Diaethylaminoaethanol
2-(Diethylamino)Ethan-1-Ol
2-(N,N-Diethylamino)ethanol
N,N-Diethylmonoethanolamine
N,N-Diethyl-2-hydroxyethylamine
beta-Diethylaminoethanol
beta-Hydroxytriethylamine
2-(Diethylamino)ethyl alcohol
Diethylamino ethanol
N-Diethylaminoethanol
2-diethylamino-ethanol
2-N-Diethylaminoethanol
diethyl ethanolamine
DEEA
beta-Diethylaminoethyl alcohol
N-(Diethylamino)ethanol
N,N-Diethyl-N-(beta-hydroxyethyl)amine
NSC 8759
N,N-Diethylaminoethanol
2-(diethylamino)-ethanol
2-N-(Diethylamino)ethanol
.beta.-(Diethylamino)ethanol
ETHANOL,2-DIETHYLAMINO
S6DL4M053U
beta-(Diethylamino)ethyl alcohol
CHEBI:52153
.beta.-(Diethylamino)ethyl alcohol
NSC-8759
N,N-Diethyl-N-(.beta.-hydroxyethyl)amine
DSSTox_CID_1837
DSSTox_RID_76358
DSSTox_GSID_21837
CAS-100-37-8
Diaethylaminoaethanol [German]
CCRIS 4793
HSDB 329
EINECS 202-845-2
UN2686
UNII-S6DL4M053U
AI3-16309
2-Diethylamino
Diathylaminoathanol
Diethylamlnoethanol
MFCD00002850
n,n-diethyl ethanolamine
N, N-Diethylethanolamine
beta-(Diethylamino)ethanol
N,N-diethyl ethanol amine
2-Diethylaminoethanol [UN2686] [Corrosive]
.beta.-Hydroxytriethylamine
EC 202-845-2
SCHEMBL3114
2-Diethylaminoethanol, 9CI
CHEMBL1183
Diaethylaminoaethanol(german)
2-(diethylamino)-1-ethanol
MLS002174251
2-(N,N-diethylamino)-ethanol
2-(Diethylamino)ethanol, 99%
DTXSID5021837
DIETHYLAMINOETHANOL [HSDB]
N-(beta-hydroxyethyl)diethylamine
NSC8759
HMS3039I08
ZINC388479
2-(Diethylamino)ethanol, >=99%
DIETHYL ETHANOLAMINE [INCI]
DIETHYLAMINOETHANOL [MART.]
WLN: Q2N2 & 2
ADAL1185323
DIETHYLAMINOETHANOL [WHO-DD]
N-(hydroxyethyl)-N,N-diethyl amine
Tox21_201463
Tox21_300037
BBL012211
STL163552
2-(DIETHYLAMINO)ETHANOL [MI]
2-(Diethylamino)ethanol, >=99.5%
AKOS000119883
UN 2686
NCGC00090925-01
NCGC00090925-02
NCGC00090925-03
NCGC00253920-01
NCGC00259014-01
A 22
BP-20552
SMR001261425
VS-03234
DB-012722
D0465
2-Diethylaminoethanol [UN2686] [Corrosive]
D88192
2-(Diethylamino)ethanol, purum, >=99.0% (GC)
Q209373
2-Diethylaminoethanol 100 microg/mL in Acetonitrile
J-520312
Diethyl ethanolamine Diethylaminoethanol 2-Hydroxytriethylamine

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