N-OCTYLAMINE (OCT)

N-Octylamine (OCT), also known as 1-aminooctane (C₈H₁₉N), is a colorless to pale yellow liquid with a faint, ammonia-like odor. 
N-Octylamine (OCT) is a versatile chemical intermediate primarily used as a building block for biocides and corrosion inhibitors. 
N-Octylamine (OCT) is mainly used to synthesize amphiphilic copolymers for polymer coating of quantum dots (QDs) to make them water-soluble.

CAS Number: 111-86-4
Molecular Formula: C8H19N
Molecular Weight: 129.24
EINECS Number: 203-916-0

Synonyms:Octylamine, n-Octylamine, N-Octylamine, 1-Octylamine, 1-Octanamine, octan-1-amine, Octanamine, 1-Aminooctane, octane-1-amine, octyl amine, octyl-amine, n-octyl-amine, N-octyl amine, 1-octyl amine, Caprylamine, Caprylylamine, Monoctylamine, Monooctylamine, Armeen 8, Armeen 8D, GENAMIN 8R, Amine 8D, CAS 111-86-4, EC 203-916-0, EINECS 203-916-0, DTXSID8021939, DTXCID401939, NSC 9824, BRN 1679227, MFCD00008247, CHEBI:7728, UNII SF0V8U4T67, RefChem:167904, Amine 8 D;Armeen 8;Armeen 8d;OCTYLAMINE;1-Aminooctan;1-AMINOOCTANE;OCTYLAMINE, STANDARD FOR GC;n-Octylamine, 99+%

N-Octylamine (OCT) is a fatty primary amine with the molecular formula C₈H₁₉N, consisting of a straight eight-carbon alkyl chain attached to an amino group (–NH₂).
N-Octylamine (OCT) is typically obtained from fatty alcohols or petrochemical feedstocks through amination processes.
This makes it an important intermediate in industrial organic chemistry.

The molecule is weakly basic due to the lone electron pair on the nitrogen atom, which allows it to react with acids to form ammonium salts and to participate in a wide range of chemical reactions.
N-Octylamine (OCT)s long hydrophobic carbon chain gives it both organic compatibility and surface-active behavior.
This makes it useful in surfactant and formulation chemistry.

N-Octylamine (OCT) is usually a colorless to pale yellow liquid with a characteristic amine odor and low water solubility but good solubility in organic solvents.
N-Octylamine (OCT) is often handled under controlled conditions due to its volatility and odor.
This makes safe handling and ventilation important.

N-Octylamine (OCT) is best described as a long-chain aliphatic amine used as a building block in surfactants, corrosion inhibitors, chemical intermediates, and specialty formulations.
Its value comes from combining basicity with hydrophobic chain behavior.
N-Octylamine (OCT) makes it widely used in industrial and formulation chemistry.

N-Octylamine (OCT) is often classified as a fatty amine, meaning it combines a long hydrophobic hydrocarbon chain with a reactive amine group, giving it both oil-like and chemically active behavior in the same molecule.
This dual nature allows it to interact with both organic and inorganic systems.
N-Octylamine (OCT) makes it highly versatile in industrial chemistry.

Its molecular structure allows it to adsorb strongly onto surfaces such as metals, clays, and mineral particles through the nitrogen atom while the hydrocarbon chain aligns outward, creating a hydrophobic protective layer.
This surface orientation is key to many of its industrial functions.
N-Octylamine (OCT) makes it important in surface modification chemistry.

N-Octylamine (OCT) can become protonated under acidic conditions, forming water-soluble ammonium salts that behave like cationic surfactants.
This transformation significantly changes its solubility and interfacial behavior.
N-Octylamine (OCT) makes it useful in pH-responsive formulations.

Because of its amphiphilic structure, it can act as a phase-transfer facilitator, helping to transport reactive species between water and organic phases during chemical reactions.
This improves reaction efficiency in biphasic systems.
N-Octylamine (OCT) makes it valuable in synthetic chemistry processes.

N-Octylamine (OCT) is widely used because its long hydrophobic chain and polar amine head allow it to behave like a “molecular bridge” between organic oils and aqueous systems, enabling it to stabilize interfaces in emulsions and dispersions.
This interfacial behavior is central to many formulation and processing applications.
N-Octylamine (OCT) makes it important in surface and colloid chemistry.

In adsorption processes, N-Octylamine (OCT) can bind strongly to negatively charged surfaces such as silica, metal oxides, and clay minerals through electrostatic attraction and hydrogen bonding interactions at the amine group.
N-Octylamine (OCT) leads to the formation of ordered surface layers that modify wettability.
This makes it useful in surface modification technologies.

When used in acidic environments, it forms octylammonium salts that significantly increase water solubility and enhance its ability to function as a cationic surfactant in aqueous systems.
This allows it to switch behavior depending on pH conditions.

N-Octylamine (OCT) makes it valuable in responsive chemical systems.
In corrosion inhibition, its performance improves with time because it can form more organized, densely packed protective films on metal surfaces, reducing permeability to oxygen and moisture.

Melting point: −5 to −1 °C (lit.)
Boiling point: 175–177 °C (lit.)
Density: 0.782 g/mL at 25 °C (lit.)
vapor pressure: 1 mm Hg (20 °C)
refractive index: n20/D 1.429 (lit.)
Flash point: 145 °F
storage temp.: Store below +30°C
solubility: 0.32 g/L
form: liquid
pKa: 10.65 (25 °C)
color: clear
pH: 11.8 (100 g/L, H2O, 25 °C)
Odor: strong fishy ammonia-like odor
explosive limit: 1.6–8.2% (V)
Water Solubility: 0.2 g/L (25 °C)
BRN: 1679227
Henry's Law Constant: 2.2 × 10^-1 mol/(m3Pa) at 25 °C
Dielectric constant: 3.58
InChI: 1S/C8H19N/c1-2-3-4-5-6-7-8-9/h2-9H2,1H3
InChIKey: IOQPZZOEVPZRBK-UHFFFAOYSA-N
SMILES: CCCCCCCCN
LogP: 3.46 at 20 °C

N-Octylamine (OCT)s reactivity as a primary amine also allows it to participate in acylation, alkylation, and condensation reactions, making it a versatile intermediate for producing more complex nitrogen-containing compounds.
These transformations expand its industrial utility beyond direct use.
N-Octylamine (OCT) makes it important in synthetic organic chemistry.

In formulation systems, N-Octylamine (OCT) is often used in combination with other surfactants because it can improve emulsifier packing at interfaces, leading to more stable oil-in-water or water-in-oil dispersions depending on system design.
This helps reduce phase separation in complex mixtures.
N-Octylamine (OCT) makes it useful in industrial formulation stability.

A yellow liquid with an ammonia-like odor. 
Insoluble in water and less dense than water. 
Hence floats on water, contact may irritate skin, eyes and mucous membranes. 

May be toxic by ingestion. 
N-Octylamine (OCT) is sed to make other chemicals.
N-Octylamine (OCT) can act as a nucleophilic reagent in organic synthesis, where the nitrogen atom attacks electrophilic centers to form amides, imines, and other nitrogen-containing derivatives.

N-Octylamine (OCT) reactivity makes it a useful intermediate for producing more complex compounds.
This makes it important in fine chemical synthesis.

Because of its long hydrophobic chain, it exhibits surface-active properties that allow it to accumulate at interfaces between water and oil phases, reducing surface tension and improving emulsification behavior.
This interfacial activity is useful in formulation science.
N-Octylamine (OCT) makes it valuable in surfactant systems.

N-Octylamine (OCT) can form salts with acids such as hydrochloric acid, organic acids, or surfactant acids, which often improves its water dispersibility and enables use in aqueous formulations.
These salt forms are commonly used in industrial products.
N-Octylamine (OCT) makes it important in formulation engineering.

N-Octylamine (OCT) is also used as a corrosion inhibitor component, where it adsorbs onto metal surfaces and forms a protective hydrophobic layer that reduces contact with water and corrosive agents.
N-Octylamine (OCT) protective film helps slow down oxidation and corrosion processes.
This makes it useful in metal protection systems.

In chemical processing, it can be used as a pH-modifying agent and intermediate in the production of quaternary ammonium compounds and other functional derivatives.
These derivatives often have stronger surfactant or antimicrobial properties.
N-Octylamine (OCT) makes it important in industrial synthesis pathways.

Due to its reactive amine group, it must be handled carefully because it can react with oxidizing agents, acids, and acylating compounds, sometimes releasing heat during neutralization or reaction processes.
This requires controlled conditions during storage and processing.
N-Octylamine (OCT) makes process safety important.

N-Octylamine (OCT) neutralizes acids in exothermic reactions to form salts plus water. 
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. 
Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

In corrosion inhibition systems, its effectiveness comes from the ability to form self-assembled, hydrophobic molecular films on metal surfaces that reduce direct contact with water, oxygen, and aggressive ions.
These films can significantly slow electrochemical corrosion reactions.
N-Octylamine (OCT) makes it important in metal protection technologies.

N-Octylamine (OCT) is also used as a precursor for quaternary ammonium compounds, which often have stronger antimicrobial, surfactant, or antistatic properties than the parent amine.
These derivatives are widely used in industrial and cleaning products.
N-Octylamine (OCT) makes it important in specialty chemical production.

N-Octylamine (OCT) is a flammable, corrosive, and strongly irritating amine that requires careful handling due to its volatility and chemical reactivity.
Exposure risks are mainly occupational and occur during handling of the liquid form.
N-Octylamine (OCT) makes industrial safety measures essential.

Direct contact can cause skin burns, eye damage, and irritation, especially with concentrated material or prolonged exposure.
Immediate washing and protective equipment are required during handling.
This makes personal protection critical.

Inhalation of vapors may lead to respiratory tract irritation, coughing, throat discomfort, and dizziness in poorly ventilated environments.
Adequate ventilation reduces exposure significantly.
N-Octylamine (OCT) makes engineering controls important.

Uses Of N-Octylamine (OCT):
N-Octylamine (OCT) is used as a precursor to prepare chemicals. 
N-Octylamine (OCT) finds application in functional fluids and as a laboratory reagent. 
Further, it is used as a reactant in the preparation of 2H-indazoles and 1H-indazolones, which are used as myeloperoxidase(MPO) inhibitors.

N-Octylamine (OCT) is mainly used to synthesize amphiphilic copolymers for polymer coating of quantum dots (QDs) to make them water-soluble.
Synthesis of 2-cyano-N-octylacetamide by reacting with ethyl cyanoacetate.
To induce uniformity for synthesizing uniform ultrathin metal sulfide nanostructures.

N-Octylamine (OCT) is used in the production of corrosion inhibitors for oilfield, cooling water, and industrial metal protection systems, where it helps form protective films on metal surfaces.
These films reduce rusting and chemical degradation.
N-Octylamine (OCT) makes it important in corrosion control chemistry.

In surfactant and detergent formulations, it is used to enhance emulsification, wetting, and interfacial activity between oil and water phases, improving cleaning and dispersion performance.
N-Octylamine (OCT) helps stabilize mixed-phase formulations.
This makes it useful in cleaning and formulation industries.

In chemical synthesis, it is used as a building block for producing amides, quaternary ammonium salts, and other nitrogen-containing specialty chemicals.
These derivatives often have enhanced surfactant or antimicrobial properties.
N-Octylamine (OCT) makes it important in fine chemical manufacturing.

In flotation and mineral processing, it is used to modify surface properties of minerals, improving separation efficiency in ore processing systems.
Its surface activity helps control particle behavior in aqueous suspensions.
N-Octylamine (OCT) makes it useful in mining and metallurgical processes.

In oil and gas applications, it is used as a chemical additive for flow assurance and corrosion protection in pipelines and production systems.
N-Octylamine (OCT) helps reduce equipment degradation and operational issues.
This makes it valuable in petroleum engineering systems.

In textile and specialty chemical applications, it is used to assist in wetting, dyeing auxiliaries, and formulation of functional finishing agents.
Its amphiphilic nature supports better interaction with fibers.
N-Octylamine (OCT) makes it useful in textile chemistry.

N-Octylamine (OCT) is used in corrosion inhibition formulations for oilfield, refinery, and cooling water systems, where it protects metal surfaces from rust and chemical attack.
It forms hydrophobic layers that reduce electrochemical corrosion.
N-Octylamine (OCT) makes it essential in industrial protection systems.

In surfactant chemistry, it is used to enhance emulsification, wetting, and dispersion of oils, waxes, and hydrophobic materials in aqueous systems.
This improves formulation stability in mixed-phase products.
This makes it valuable in detergent and formulation industries.

In chemical synthesis, it is used as a building block for amides, imides, and quaternary ammonium salts used in advanced functional materials.
These derivatives often show enhanced surface or antimicrobial properties.
This makes it important in fine chemical manufacturing.

In flotation and mineral processing, it is used to modify mineral surface charge and hydrophobicity, improving separation efficiency of ores in aqueous slurry systems.
This helps selectively bind or repel particles during processing.
N-Octylamine (OCT) makes it useful in mining chemistry.

In oil and gas operations, it is used as a flow assurance and treatment additive to reduce corrosion and improve pipeline reliability under harsh operating conditions.
It helps maintain stable transport of hydrocarbons and water mixtures.
N-Octylamine (OCT) makes it valuable in petroleum engineering.

In textile and auxiliary chemical applications, it is used to assist dyeing processes and improve wetting of fibers during finishing treatments.
This enhances penetration and uniformity of treatment chemicals.
N-Octylamine (OCT) makes it useful in textile processing chemistry.

N-Octylamine (OCT) is used in corrosion inhibition systems for oilfield pipelines, refineries, and cooling water circuits, where it protects metal surfaces by forming hydrophobic protective films.
This reduces rusting and chemical attack in harsh environments.
N-Octylamine (OCT) makes it essential in industrial corrosion control.

In surfactant and emulsifier formulations, it is used to stabilize mixtures of oil and water by reducing interfacial tension and improving dispersion of hydrophobic substances.
This enhances product stability and performance.
N-Octylamine (OCT) makes it valuable in chemical formulation industries.

In chemical synthesis, it is used as a starting material for producing quaternary ammonium salts, amides, and other functional derivatives with enhanced surface activity or antimicrobial properties.
These derivatives are widely used in specialty chemicals.
N-Octylamine (OCT) makes it important in fine chemical production.

In mineral processing and flotation, it is used to modify mineral surface properties to improve separation efficiency of valuable ores from gangue materials in aqueous slurries.
This improves selectivity during industrial extraction processes.
N-Octylamine (OCT) makes it useful in mining chemistry.

In oil and gas systems, it is used as a treatment additive for flow assurance, helping reduce corrosion and improve the stability of multiphase transport systems.
This enhances operational reliability in pipelines.
N-Octylamine (OCT) makes it valuable in petroleum engineering applications.

In textile and auxiliary chemical applications, it is used to enhance wetting and penetration of processing chemicals into fibers, improving dye uniformity and finishing quality.
N-Octylamine (OCT) improves textile processing efficiency.
This makes it useful in textile chemical engineering.

Safety Profile Of N-Octylamine (OCT):
N-Octylamine (OCT) is a flammable and corrosive irritant chemical that requires careful handling due to its volatility, odor, and reactivity as a primary amine.
Most risks arise from direct exposure and improper storage.
N-Octylamine (OCT) makes industrial safety procedures essential.

Direct contact may cause skin burns, eye irritation, and tissue damage, especially in concentrated form or with prolonged exposure.
Protective gloves, goggles, and protective clothing are required.
N-Octylamine (OCT) makes personal protective equipment important.

Inhalation of vapors may cause respiratory irritation, coughing, throat discomfort, and dizziness, particularly in poorly ventilated environments.
Proper ventilation significantly reduces exposure risk.
N-Octylamine (OCT) makes engineering controls necessary.

Because it is a reactive amine, it can undergo exothermic reactions when neutralized with acids or when reacting with strong oxidizing agents, which may release heat and potentially hazardous fumes.
Careful process control is therefore required.
N-Octylamine (OCT) makes reaction safety important.

N-Octylamine (OCT) is also combustible, and its vapors may form flammable mixtures with air under certain conditions, requiring strict fire prevention measures.
Storage away from ignition sources is necessary.
N-Octylamine (OCT) makes flammability management important.

Environmental release should be avoided because amines can be toxic to aquatic organisms at elevated concentrations and may alter local pH conditions in water systems.
N-Octylamine (OCT) is a flammable, corrosive, and strongly irritating amine that must be handled under controlled industrial conditions due to its vapor exposure and chemical reactivity.