n-Tetracosyl alcohol is widely used as an ingredient in cosmetics, personal care products, pharmaceutical formulations, industrial waxes, lubricants, and specialty chemical manufacturing.
n-Tetracosyl alcohol is used in polymers and plastics it can function as a wax-like additive and processing aid to improve softness, gloss, and processability of plastic and wax systems; in coatings and inks it is used as a wax-like additive.
CAS Number: 506-51-4
EC Number: 208-046-5
Chemical formula: C24H50O
Molar mass: 354.663 g·mol−1
SYNONYMS:
N-Tetracosyl Alcohol, 1-Tetracosanol, Tetracosan-1-ol, n-Tetracosanol, Lignoceryl alcohol, Lignoceryl Alcohol, Tetracosyl Alcohol, C24 Alcohol, Tetracosan-1-ol, Lignoceryl alcohol, 1-Tetracosanol, 506-51-4, Tetracosan-1-ol, LIGNOCERYL ALCOHOL, Lignocerol, n-Tetracosanol, Tetracosyl alcohol, Lignoceric alcohol, n-Tetracosanol-1, HSDB 5674, UNII-2N0PI37IOC, EINECS 208-043-9, 2N0PI37IOC, NSC 93768, NSC-93768, DTXSID8027161, CHEBI:77413, EC 208-043-9, RefChem:25873, DTXCID107161, TETRACOSANOL (CONSTITUENT OF SAW PALMETTO), 208-043-9, Tetracosanol, MFCD00042662, A1EM1, SCHEMBL17228, orb1296995, SCHEMBL1610834, SCHEMBL4756477, SCHEMBL4756480, LIGNOCERYL ALCOHOL [HSDB], FOH 24:0, NSC93768, LMFA05000222, TN6753, AKOS015839851, EBC-617702, HY-W127492, AS-56560, BP-41337, SY052177, Lignoceryl alcohol, >=99% (capillary GC), CS-0185720, NS00007752, T72542, F828252, Q2806593, 1-Tetracosanol 10 |Ig/mL in Methyl-tert-butyl ether, 1-Tetracosanol 10 microg/mL in Methyl-tert-butyl ether, TETRACOSANOL (CONSTITUENT OF SAW PALMETTO) [DSC], Lignoceric alcohol, Lignoceryl alcohol, 1-Tetracosanol, Tetracosan-1-ol, Tetracosyl alcohol, Lignocerol, Tetracosanol, Myristyl alcohol, Tetradecyl alcohol
n-Tetracosyl alcohol, 1-Tetracosanol (lignoceryl alcohol), is a fatty alcohol containing 24 carbon atoms, usually derived from the fatty acid lignoceric acid.
n-Tetracosyl alcohol is a very long-chain primary fatty alcohol that is tetracosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group.
n-Tetracosyl alcohol has been isolated from a variety of plants, including grape seeds, evening primrose (Oenothera biennis), pitaya fruits (Hylocereus polyrhizus and Hylocereus undatus), and the flowers of Arabian jasmine ( Jasminum sambac).
n-Tetracosyl alcohol has a role as a vulnerary and a plant metabolite.
n-Tetracosyl alcohol is a very long-chain primary fatty alcohol and a tetracosanol.
n-Tetracosyl alcohol has been reported in Castanopsis lanceifolia, Artemisia igniaria, and other organisms with data available.
n-Tetracosyl alcohol, 1-Tetradecanol, with the CAS number 112-72-1, is a long-chain fatty alcohol characterized by its straight-chain structure consisting of 14 carbon atoms and a hydroxyl (-OH) functional group.
n-Tetracosyl alcohol is a colorless, waxy solid at room temperature and has a mild, fatty odor.
n-Tetracosyl alcohol is insoluble in water but soluble in organic solvents such as ethanol and ether, which is typical for long-chain alcohols.
n-Tetracosyl alcohol, also known as fatty alcohol, is an organic compound that is a straight chain fatty alcohol composed of fourteen carbon atoms.
Lipotic alcohols are a class of aliphatic compounds, usually obtained by chemical reactions from natural vegetable oils or animal fat.
Tedecenecols belong to alcohols in chemical structure, and because of carbon chain length due to certain physical properties and wide application fields.
n-Tetracosyl Alcohol is a long-chain saturated primary fatty alcohol containing 24 carbon atoms.
Its IUPAC name is tetracosan-1-ol, and n-Tetracosyl alcohol belongs to the family of higher aliphatic alcohols commonly found in natural waxes such as beeswax, plant waxes, carnauba wax, and cuticular waxes on leaves and fruits.
At room temperature, n-Tetracosyl alcohol appears as a white crystalline solid or waxy substance with little to no noticeable odor.
Due to its long hydrocarbon chain, N-tetracosyl alcohol exhibits excellent hydrophobicity, lubricity, and film-forming properties.
n-Tetracosyl alcohol is widely used as an ingredient in cosmetics, personal care products, pharmaceutical formulations, industrial waxes, lubricants, and specialty chemical manufacturing.
Unlike short-chain alcohols, n-Tetracosyl alcohol is non-volatile and has relatively low acute toxicity, making it suitable for applications requiring stable, water-resistant coatings and formulations.
USES and APPLICATIONS of N-TETRACOSYL ALCOHOL:
n-Tetracosyl alcohol is a long-chain fatty alcohol (C24) used in cosmetics and personal care as an emollient and thickener; in perfumery as a fragrance fixative to extend scent.
n-Tetracosyl alcohol is used in polymers and plastics it can function as a wax-like additive and processing aid to improve softness, gloss, and processability of plastic and wax systems; in coatings and inks it is used as a wax-like additive
n-Tetracosyl alcohol exhibits properties such as being a surfactant and emulsifier, making it useful in various applications, including cosmetics, personal care products, and as a lubricant.
n-Tetracosyl alcohol's melting point is relatively high compared to shorter-chain alcohols, reflecting its hydrophobic nature.
Additionally, n-Tetracosyl alcohol can undergo typical alcohol reactions, such as oxidation to form aldehydes or acids.
Due to its fatty nature, n-Tetracosyl alcohol is also used in the production of esters for fragrances and flavorings.
n-Tetracosyl alcohol is valued for its functional properties in industrial and consumer products.
Research Applications of n-Tetracosyl alcohol is frequently used in research involving: plant wax chemistry, lipid metabolism, long-chain alcohol analysis, chromatographic standards, surface chemistry.
-Cosmetics and Personal Care uses of n-Tetracosyl alcohol:
N-Tetracosyl alcohol is widely used in cosmetic formulations because it improves texture, stability, and moisture retention.
n-Tetracosyl alcohol is commonly found in: creams, lotions, lipsticks, balms, ointments, conditioners, skincare products.
n-Tetracosyl alcohol functions as an emollient, viscosity modifier, thickening agent, and protective film former.
-Pharmaceutical Applications of n-Tetracosyl alcohol:
In pharmaceutical formulations, N-Tetracosyl alcohol serves as an excipient that improves the consistency and stability of topical preparations.
n-Tetracosyl alcohol is used in: ointments, medicated creams, controlled-release formulations, protective skin preparations.
n-Tetracosyl alcohol's waxy structure helps regulate moisture loss and improve product durability.
-Wax Manufacturing uses of n-Tetracosyl alcohol:
n-Tetracosyl alcohol is an important ingredient in specialty wax formulations because of its hardness and water resistance.
Applications include: polishing waxes, protective coatings, industrial wax blends, candle formulations, leather treatments.
-Industrial Lubricants uses of n-Tetracosyl alcohol:
n-Tetracosyl alcohol's long hydrocarbon chain provides excellent boundary lubrication.
n-Tetracosyl alcohol is used in: specialty lubricants, metal processing, textile finishing, mold release formulations.
n-Tetracosyl alcohol reduces friction while providing a durable protective surface.
-Chemical Intermediate uses of n-Tetracosyl alcohol:
N-Tetracosyl alcohol serves as a starting material for manufacturing: fatty esters, surfactants, emulsifiers, specialty lubricants, wax derivatives, industrial additives.
n-Tetracosyl alcohol's primary alcohol functionality allows efficient chemical modification.
BENEFITS of N-TETRACOSYL ALCOHOL:
N-Tetracosyl alcohol offers numerous practical advantages across multiple industries.
n-Tetracosyl alcohol's benefits include:
excellent moisture barrier properties,
superior film formation,
high chemical stability,
low volatility,
natural occurrence in biological waxes,
effective lubrication,
good compatibility with wax formulations,
biodegradable behavior under suitable environmental conditions,
useful chemical versatility through its hydroxyl group.
CHEMICAL BEHAVIOR of N-TETRACOSYL ALCOHOL:
The hydroxyl group provides the primary reactive site of n-Tetracosyl alcohol, while the long hydrocarbon chain contributes exceptional hydrophobic character.
N-Tetracosyl alcohol readily undergoes:
esterification with carboxylic acids,
oxidation to tetracosanoic acid,
ether formation,
reactions producing surfactants and wax derivatives.
n-Tetracosyl alcohol remains chemically stable under ordinary storage conditions and does not readily polymerize.
CHARACTERISTICS of N-TETRACOSYL ALCOHOL:
N-Tetracosyl alcohol possesses several distinctive characteristics that make it valuable in industrial and commercial applications.
n-Tetracosyl alcohol is:
highly hydrophobic,
wax-forming,
non-volatile,
chemically stable,
biodegradable,
lubricating,
film-forming,
moisture-resistant.
Its combination of a long hydrocarbon chain and a reactive hydroxyl group allows n-Tetracosyl alcohol to function both as a protective wax component and as a useful chemical intermediate.
INDUSTRIAL PRODUCTION of N-TETRACOSYL ALCOHOL:
Commercial production of N-Tetracosyl alcohol is typically achieved through catalytic hydrogenation of tetracosanoic acid derivatives or natural wax feedstocks.
Production methods include:
hydrogenation of fatty acid esters,
reduction of long-chain aldehydes,
purification from natural waxes such as beeswax and plant waxes.
These methods produce high-purity material suitable for cosmetic, pharmaceutical, and industrial applications.
SCIENTIFIC INFORMATION of N-TETRACOSYL ALCOHOL:
Naturally present in beeswax, carnauba wax, and plant cuticular waxes.
n-Tetracosyl alcohol contributes to the water-repellent properties of plant surfaces.
n-Tetracosyl alcohol acts as a structural component in natural protective wax layers.
n-Tetracosyl alcohol is useful as a chromatographic reference standard for long-chain alcohol analysis.
n-Tetracosyl alcohol exhibits excellent compatibility with lipid-based formulations.
n-Tetracosyl alcohol provides hardness and durability in wax mixtures.
n-Tetracosyl alcohol's long saturated carbon chain contributes exceptional oxidative stability compared with unsaturated fatty alcohols.
n-Tetracosyl alcohol is frequently studied in lipidomics and plant surface chemistry because of its role in biological wax composition.
PHYSICAL and CHEMICAL PROPERTIES of N-TETRACOSYL ALCOHOL:
Appearance: White crystalline solid or wax-like flakes.
Odor: Odorless or nearly odorless.
Physical State: Solid at room temperature.
Molecular Formula: C₂₄H₅₀O.
Molecular Weight: 354.65 g/mol.
CAS Number: 506-51-4.
EC Number: 208-046-5.
Density: Approximately 0.82 g/cm³ (near melting temperature).
Melting Point: Approximately 74–76°C.
Boiling Point: Approximately 390–400°C (decomposes near boiling).
Flash Point: Above 180°C.
Vapor Pressure: Extremely low at room temperature.
Refractive Index: Approximately 1.44.
Evaporation Rate: Negligible under normal conditions.
Color: White to off-white.
Texture: Waxy and crystalline.
Chemical Properties
Chemical Class: Long-chain primary fatty alcohol.
Functional Group: Primary alcohol (-CH₂OH).
Carbon Chain Length: 24 carbon atoms.
Saturation: Fully saturated.
Polarity: Amphiphilic, with a hydrophobic hydrocarbon chain and a polar hydroxyl group.
Water Solubility: Practically insoluble.
Solubility: Soluble in ethanol (when heated), ether, chloroform, benzene, and other organic solvents.
XLogP: Very high (approximately 10–11), reflecting strong lipophilicity.
Hydrogen Bond Donor Count: 1.
Hydrogen Bond Acceptor Count: 1.
Rotatable Bond Count: 23.
Topological Polar Surface Area: Approximately 20 Ų.
Exact Mass: 354.386 g/mol.
Heavy Atom Count: 25.
Formal Charge: 0
Chemical formula: C24H50O
Molar mass: 354.663 g·mol−1
Melting point: 75 °C (167 °F; 348 K)
Solubility in water: 0.001 g/L (23 °C)
Hazards
Flash point: 218 °C (424 °F; 491 K)
Molecular Weight: 354.7 g/mol
XLogP3: 11.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 22
Exact Mass: 354.386166214 Da
Monoisotopic Mass: 354.386166214 Da
Topological Polar Surface Area: 20.2 Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 214
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molecular Formula / Molecular Weight: C24H50O = 354.66
Physical State (20 deg.C): Solid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN: 506-51-4
Reaxys Registry Number: 1777129
PubChem Substance ID: 87576489
SDBS (AIST Spectral DB): 10902
MDL Number: MFCD00042662
Linear Formula: CH3(CH2)13OH
CAS Number: 112-72-1
Molecular Weight: 214.39
NACRES: NA.22
PubChem Substance ID: 24850687
eCl@ss: 39020231
UNSPSC Code: 12352100
EC Number: 204-000-3
MDL number: MFCD00004757
Beilstein/REAXYS Number: 1742652
Assay: 97%
Form: solid
Physical state: solid
Color: colorless
Odor: characteristic
Melting point/freezing point
Melting point/range: 35 - 39 °C - lit.
Initial boiling point and boiling range
289 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 148 °C - closed cup
Autoignition temperature: ca.259 °C at 1.013 hPa
Decomposition temperature: No data available
pH: No data available
Viscosity: Viscosity, kinematic: 2,845 mm2/s at 100 °C - ASTM D 445
Viscosity, dynamic: No data available
Water solubility: 0,0013 g/l at 23 °C - slightly soluble
Partition coefficient: n-octanol/water
log Pow: 5,5
Vapor pressure: ca.0,008 hPa at ca.38 °C
Density: 0,823 g/mL at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
FIRST AID MEASURES of N-TETRACOSYL ALCOHOL:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of N-TETRACOSYL ALCOHOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of N-TETRACOSYL ALCOHOL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of N-TETRACOSYL ALCOHOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of N-TETRACOSYL ALCOHOL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of N-TETRACOSYL ALCOHOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
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