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Neopentyl Glycol Diheptanoate belongs to a chemical group called monoalkyl (Neo-pentyl) glycol dialkyl (diheptanoic) acid esters.
Neopentyl Glycol Diheptanoate is a fatty acid obtained from grapes juice.
Neopentyl glycol diheptanoate is a clear, light straw-colored, odorless and very light ester.
CAS Number: 68855-18-5
Molecular Formula: C19H36O4
Molecular Weight: 328.48674
EINECS Number: 272-469-1
Synonyms: Heptanoic acid, ester with 2,2-dimethyl-1,3-propanediol;NEOPENTYL GLYCOL DIHEPTANOATE;Heptansure, Ester mit 2,2-Dimethyl-1,3-propandiol;Neopentyl Glycol Diheptanoate (NGDH)
Neopentyl Glycol Diheptanoate is a light emollient that offers sensory properties similar to cyclomethicone.
Neopentyl Glycol Diheptanoate is colorless and has no odor.
The most common cosmetic uses are: Skin and hair conditioning agent, Film former, Opacifying agent, Slip modifier, Sensorial agent, Active carrier, Surface modifier, Spreading agent.
Due to its special properties, cosmetic manufacturers like to use Neopentyl Glycol Diheptanoate for color cosmetics, skin care, hair care, sun care, and antiperspirant formulations.
Neopentyl Glycol Diheptanoate delivers a smooth, non-oily, silky feel.
Neopentyl glycol diheptanoate is a combination of Neopentyl glycol and heptanoic acid.
Neopentyl Glycol Diheptanoate is an organic chemical compound.
Neopentyl Glycol Diheptanoate is used in the synthesis of polyesters, paints, lubricants, and plasticizers.
When used in the manufacture of polyesters, it enhances the stability of the product towards heat, light, and water.
By esterification reaction with fatty or carboxylic acids, synthetic lubricating esters with reduced potential for oxidation or hydrolysis, compared to natural esters, can be produced.
Neopentyl glycol diheptanoate is an organic chemical compound classified as a diester formed by the esterification reaction between neopentyl glycol, a branched diol with two hydroxyl groups on a propane backbone, and heptanoic acid, a seven-carbon saturated fatty acid also known as enanthic acid.
This chemical structure results in a molecule where the neopentyl glycol core is linked to two heptanoate (heptanoic acid-derived) ester groups, creating a compound that combines the rigidity and stability of neopentyl glycol with the hydrophobic, lipophilic characteristics of the relatively long seven-carbon alkyl chains from the heptanoate moieties.
Neopentyl Glycol Diheptanoate is synthesized industrially by the aldol reaction of formaldehyde and isobutyraldehyde.
This creates the intermediate hydroxypivaldehyde, which can be converted to neopentyl glycol by either a Cannizzaro reaction with excess formaldehyde, or by hydrogenation using palladium on carbon.
Owing to its tendency to form cyclic derivatives (see Thorpe-Ingold Effect), it is used as a protecting group for ketones, for example in gestodene synthesis.
Neopentyl Glycol Diheptanoate gives boronic acid esters, which can be useful in the cross coupling reactions.
A condensation reaction of neopentyl glycol with 2,6-di-tert-butylphenol gives CGP-7930.
Neopentyl Glycol Diheptanoate is a precursor to Neopentyl glycol diglycidyl ether.
The sequence begins with alkylation with epichlorohydrin using a Lewis acid catalyst.
Neopentyl Glycol Diheptanoate of the resulting halohydrin with sodium hydroxide affords the desired ether.
Neopentyl Glycol Diheptanoate has been reported that plastic crystals of neopentyl glycol exhibit a colossal barocaloric effect (CBCEs), which is a cooling effect caused by pressure-induced phase transitions.
The obtained entropy changes are about 389 joules per kilogram per kelvin near room temperature.
This CBCE phenomenon is likely to be very useful in future solid-state refrigeration technologies.
Neopentyl glycol diheptanoate is a mixture of texture-enhancing ingredient neopentyl glycol and grape-derived fatty acid heptanoic acid.
Neopentyl Glycol Diheptanoate functions as a non-aqueous skin-softening agent (emollient) and formulary thickening agent.
Neopentyl Glycol Diheptanoate is an emollient that offer similar sensory properties are excellent alternatives as replacements for cyclomethicones.
It has a colorless and it has no odor.
The most common cosmetic uses for Neopentyl Glycol Diheptanoate are: Skin and hair conditioning agent, Film former, Opacifying agent, Slip modifier, Sensorial agent, Active carrier, Surface modifier, Spreading agent.
Neopentyl Glycol Diheptanoate is a clear, odorless and very light emollient ester that helps achieve light textures.
It has excellent spreading properties and a silky feel on the skin.
Neopentyl Glycol Diheptanoate is ideal for solubilizing sunscreens and fragrances.
Neopentyl Glycol Diheptanoate is also touted as a volatile (evaporates from the skin rather than absorbing it) alternative to silicones, notably as a replacement for cyclomethicone-based blends.
Due to this molecular configuration, neopentyl glycol diheptanoate exhibits properties such as high thermal and oxidative stability, low volatility, and excellent lubricity, which make it suitable for a variety of industrial applications.
Neopentyl Glycol Diheptanoate's ester groups allow it to function as a plasticizer, lubricant, or intermediate in the synthesis of polymers and specialty chemicals.
Its stability and resistance to degradation under heat and chemical exposure enable materials formulated with neopentyl glycol diheptanoate to maintain flexibility and durability in demanding environments.
Density: 0.92[at 20℃]
EWG's Food Scores: 1
Neopentyl glycol diheptanoate is mainly used for formulation enhancement purposes.
Neopentyl Glycol Diheptanoate brings good spreadability and specially used in a product meant for use on the larger area of skin.
So it can bring a smooth and silky feel which is desirable in any topical lotion or cream.
Neopentyl Glycol Diheptanoate is fatty so it gets absorbed relatively quickly on to the skin, because of skin’s fatty secretions.
Neopentyl Glycol Diheptanoate also forms a protective layer that retains the skin’s inherent moisture and doesn’t let the skin dry.
It is also known to have good emollient; thus properly moisturized skin is the very first defense against any skin related problems.
Neopentyl Glycol Diheptanoate is a very good alternative to silicones, for increasing viscosity of any products, since different formulations are desirable to have different consistency for best results, for example, a lotion is not as thicker as cream.
It is used in many formulations of creams, lotions and other skincare products.
Neopentyl Glycol Diheptanoate is a biomass-balanced light emollient ester.
Neopentyl Glycol Diheptanoate forms a non-occlusive, protective layer that retains skin moisture longer, preventing dryness.
It is easy to formulate, integrating well into various formulations with desirable effects on appearance, skin feel.
Neopentyl Glycol Diheptanoate is compatible with a wide range of ingredients and a suitable alternative to decamethylcyclopentasiloxane (D5) silicone.
In sunscreens, Neopentyl Glycol Diheptanoate ensures excellent solubility and spreadability of organic UV filters, preventing crystallization for smooth and even application.
It aids solubility and dispersion of actives and pigments in color cosmetics.
Neopentyl Glycol Diheptanoate enhances the texture, providing a silky and lightweight feel that improves the application and wear of products such as foundations, lipsticks, and eyeshadows, ensuring consistent and vibrant color payoff.
It is effective in sun care, skin care, hair care, and antiperspirant applications.
In the realm of lubricants, neopentyl glycol diheptanoate is often used as a synthetic base fluid or additive, contributing to reduced friction and wear between mechanical parts.
This property is particularly valuable in automotive, aerospace, and industrial machinery applications, where components are subjected to high temperatures and mechanical stress.
Neopentyl Glycol Diheptanoate’s excellent film-forming ability ensures effective lubrication, thereby extending the service life of machinery and reducing maintenance costs.
Additionally, neopentyl glycol diheptanoate serves as a plasticizer in polymer formulations such as polyesters, polyurethanes, and epoxy resins, where it enhances the flexibility, toughness, and overall mechanical performance of the materials.
By improving these characteristics, it enables the production of coatings, adhesives, sealants, and elastomers that withstand thermal cycling, mechanical strain, and environmental exposure without cracking or degrading.
Neopentyl Glycol Diheptanoate also finds application as an intermediate in specialty chemical syntheses, where its bifunctional ester groups provide reactive sites for further chemical modifications, enabling the design and manufacture of tailored materials with specific physical and chemical properties.
Uses:
Neopentyl Glycol Diheptanoate is a skin-conditioning and viscosity increasing agent, it is also emollient.
Neopentyl Glycol Diheptanoate is a versatile chemical compound that plays a significant role in various industrial applications due to its unique molecular structure, which imparts excellent thermal stability, lubricity, and plasticizing properties.
One of its primary uses is as a synthetic lubricant base fluid or additive in the formulation of high-performance lubricants.
In automotive engines, industrial machinery, and aerospace equipment, neopentyl glycol diheptanoate helps reduce friction and wear by forming a durable lubricating film on metal surfaces, even under conditions of high temperature and mechanical stress.
This contributes to improved efficiency, longer equipment life, and reduced maintenance costs.
In the polymer industry, Neopentyl Glycol Diheptanoate is commonly used as a plasticizer to enhance the flexibility, toughness, and durability of polymers such as polyesters, polyurethanes, and epoxy resins.
Its ability to impart softness and resistance to cracking makes it valuable in producing coatings, adhesives, sealants, and elastomers that must withstand mechanical strain and environmental factors like temperature fluctuations and moisture exposure.
For example, coatings formulated with Neopentyl Glycol Diheptanoate exhibit improved flow and leveling characteristics, resulting in smooth, uniform surfaces with enhanced resistance to UV degradation and chemical attack.
The compound also serves as an intermediate in specialty chemical synthesis, where its ester groups enable chemical modifications to create customized materials with desired properties.
These tailored materials find use in advanced applications such as electronic encapsulants, flexible packaging, and high-performance composites.
Moreover, neopentyl glycol diheptanoate is utilized in the production of functional fluids that require low volatility and high oxidative stability, such as hydraulic fluids, gear oils, and metalworking fluids.
Neopentyl Glycol Diheptanoates chemical resilience helps maintain consistent performance under thermal and oxidative stress, ensuring reliability in demanding industrial environments.
In niche applications, neopentyl glycol diheptanoate’s combination of hydrophobicity and thermal stability makes it suitable as a carrier solvent or plasticizing agent in formulations requiring compatibility with both organic and polymeric components.
Neopentyl Glycol Diheptanoate’s uses span across lubrication, polymer enhancement, specialty chemical synthesis, and functional fluids, where it contributes significantly to improving performance, durability, and chemical resistance.
Its multifunctionality makes it a valuable ingredient in manufacturing processes aimed at producing durable, high-performance materials for automotive, industrial, aerospace, electronics, and coatings industries.
Safety Profile:
Neopentyl glycol diheptanoate generally exhibits a low acute toxicity profile, but it still poses several health and safety hazards that must be considered when handling, storing, or using this chemical in industrial or laboratory settings.
The compound primarily poses risks through skin and eye contact, where it can cause mild to moderate irritation.
Prolonged or repeated exposure may lead to redness, itching, or dermatitis on the skin, and direct contact with the eyes may result in irritation, redness, or watering.
Appropriate personal protective equipment (PPE) such as gloves, safety goggles, and protective clothing should be worn to minimize direct contact and reduce the risk of irritation.
Inhalation of vapors, mists, or aerosols containing neopentyl glycol diheptanoate is generally unlikely under normal handling conditions due to its low volatility.
However, in poorly ventilated environments or during processes that generate aerosols or fine droplets, respiratory tract irritation may occur.
Symptoms of inhalation exposure include coughing, throat discomfort, and shortness of breath.
Adequate ventilation, respiratory protection, and dust control measures are recommended in such scenarios to prevent inhalation risks.
Accidental ingestion of neopentyl glycol diheptanoate can cause gastrointestinal irritation, nausea, vomiting, and abdominal discomfort.
Although severe systemic toxicity is not commonly associated with Neopentyl Glycol Diheptanoate, ingestion should be avoided, and good industrial hygiene practices such as washing hands before eating or drinking must be observed to prevent accidental ingestion.
