Quick Search
Nicotinic acid is sometimes referred to as nicotinic acid or nicotinamide and earlier called the P-P factor, antipellagra factor, antiblacktongue factor, and vitamin B4, niacin is available in several forms (niacin, niacinamide, niacinamide ascorbate, etc.) for use as a nutrient and dietary supplement.
Nicotinic acid is frequently identified with the B complex vitamin grouping.
Nicotinic acid and nicotinamide are colorless crystalline substances.
CAS Number: 59-67-6
Molecular Formula: C6H5NO2
Molecular Weight: 123.11
EINECS Number: 200-441-0
Synonyms: Nicotinic acid, Niacin, Vitamin B3, Pyridine-3-carboxylic acid, 3-pyridinecarboxylic acid, 3-Carboxypyridine, 3-Carboxylpyridine, 3-Pyridylcarboxylic acid, 3-Pyridyl carboxylic acid, 3-pyridine carboxylic acid, Pyridine-beta-carboxylic acid, Pyridine-.beta.-carboxylic acid, beta-pyridinecarboxylic acid, m-Pyridinecarboxylic acid, Nicotine acid, Acidum nicotinicum, Acide nicotinique, Acido nicotinico, Nicotinsaure, Nikotinsaeure, Niacine, Vitamin B-3, Niacin-Vitamin B3, Nicotinic acid (Vitamin B3), Niacin (nicotinic acid), Nicotinic acid (Niacin), Wampocap, Niaspan, Niacor, Nico-Span, Tega-Span, Enduracin, Slo-niacin, SK-Niacin, Nicolar, Apelagrin, Pellagrin, Pellagramin, Akotin, Daskil, Efacin, Pelonin, Linic, Nicamin, Nicobid, Nicocap, Nicodelmine, Niconacid, Nicotinipca, Direktan, Nicacid, Nicangin, Peviton, Bionic, Diacin, Nicyl, Nyclin, Niac, Vitaplex N, Davitamon PP, Nicocidin, Nicocrisina, Niconazid, Nicotamin, Nicotene, Nicovasan, Nicovasen, Nipellen, Naotin, Nicodon, Niconat, Nicosan 3, Nicosyl, Nicotil, Tinic, Nicodan, Nicoside, NICO, Nico-400, Nicagin, Anti-pellagra vitamin, PP Factor, P.P. factor, Pellagra preventive factor, Preventative factor, Niacin extended release, Induracin.
Nicotinic acid is slightly soluble in water and ethanol; nicotinamide is very soluble in water and moderately soluble in ethanol.
Nicotinic acids car boxyl group can form esters and anhydrides and can be reduced.
Both nicotinic acid and nicotinamide are very stable in dry form, but in solution nicotinamide is hydro lyzed by acids and bases to yield nicotinic.
The coenzyme forms of niacin are the pyridine nucleotides, NAD(H) and NADP(H).
In each of these compounds, the electron-withdrawing effect of the N-1 atom and the amide group of the oxidized pyridine nucleus enables the pyridine C-4 atom to react with many nucleophilic agents (e.g., sulfite, cyanide, and hydride ions).
It is the reaction with hydride ions (H?) that is the basis of the enzymatic hydrogen transfer by the pyridine nucleotides; the reaction involves the transfer of two electrons in a single step
Several substituted pyridines are antagonists of niacin in biological systems: pyridine-3-sulfonic acid, 3-acetylpyridine, isonicotinic acid hydrazine, 17 and 6-aminonicotinamide.
Nicotinic acid was discovered by the oxidation of nicotine.
Nicotinic acid is derived from nicotinic acid + vitamin, as the name to be given to it is not intended to evoke nicotine.
Nicotinic acid can be seen in ancient texts that the name vitamin PP (short for the English term "pellegra prevention") was used for Nicotinic acid.
Nicotinic acid is a B vitamin that's made and used by your body to turn food into energy.
Nicotinic acid helps keep your nervous system, digestive system and skin healthy.
Nicotinic acid (vitamin B-3) is often part of a daily multivitamin, but most people get enough niacin from the food they eat.
Foods rich in Nicotinic acid include yeast, milk, meat, tortillas and cereal grains.
People use prescription Nicotinic acid (Niacor, Niaspan) to help control their cholesterol.
The recommended daily amount of Nicotinic acid for adult males is 16 milligrams (mg) a day and for adult women who aren't pregnant, 14 mg a day.
Nicotinic acid, or vitamin B3, is a water-soluble B vitamin found naturally in some foods, added to foods, and sold as a supplement.
The two most common forms of Nicotinic acid in food and supplements are nicotinic acid and nicotinamide.
The body can also convert tryptophan—an amino acid—to nicotinamide.
Nicotinic acid is water-soluble so that excess amounts the body does not need are excreted in the urine.
Nicotinic acid works in the body as a coenzyme, with more than 400 enzymes dependent on it for various reactions.
Nicotinic acid helps to convert nutrients into energy, create cholesterol and fats, create and repair DNA, and exert antioxidant effects.
Niacin, also known as nicotinic acid, is an organic compound and a vitamer of vitamin B3, an essential human nutrient.
Nicotinic acid can be manufactured by plants and animals from the amino acid tryptophan.
Nicotinic acid is obtained in the diet from a variety of whole and processed foods, with highest contents in fortified packaged foods, meat, poultry, red fish such as tuna and salmon, lesser amounts in nuts, legumes and seeds.
Nicotinic acid as a dietary supplement is used to treat pellagra, a disease caused by niacin deficiency.
Signs and symptoms of pellagra include skin and mouth lesions, anemia, headaches, and tiredness.
Many countries mandate its addition to wheat flour or other food grains, thereby reducing the risk of pellagra.
The amide derivative Nicotinic acid (niacinamide) is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP+).
Although Nicotinic acid and nicotinamide are identical in their vitamin activity, nicotinamide does not have the same pharmacological, lipid-modifying effects or side effects as niacin, i.e., when niacin takes on the -amide group, it does not reduce cholesterol nor cause flushing.
Nicotinic acid is recommended as a treatment for niacin deficiency because it can be administered in remedial amounts without causing the flushing, considered an adverse effect.
Nicotinic acid (also known as vitamin B3) is one of the water-soluble B vitamins.
Nicotinic acid is the generic name for nicotinic acid (pyridine-3-carboxylic acid), nicotinamide (niacinamide or pyridine-3-carboxamide), and related derivatives, such as nicotinamide riboside.
Nicotinic acid is naturally present in many foods, added to some food products, and available as a dietary supplement.
Nicotinic acid is a pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Nicotinic acid has a role as an antidote, an antilipemic drug, a vasodilator agent, a metabolite, an EC 3.5.1.19 (nicotinamidase) inhibitor, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a plant metabolite.
Nicotinic acid is a vitamin B3, a pyridinemonocarboxylic acid and a pyridine alkaloid.
Nicotinic acid is a conjugate acid of a nicotinate.
Nicotinic acid, or vitamin B3, is a water-soluble B vitamin found naturally in some foods, added to foods, and sold as a supplement.
The two most common forms of Nicotinic acid in food and supplements are nicotinic acid and nicotinamide.
The body can also convert tryptophan—an amino acid—to nicotinamide.
Nicotinic acid is water-soluble so that excess amounts the body does not need are excreted in the urine.
Nicotinic acid works in the body as a coenzyme, with more than 400 enzymes dependent on it for various reactions.
Nicotinic acid helps to convert nutrients into energy, create cholesterol and fats, create and repair DNA, and exert antioxidant effects.
Nicotinic acid is also a prescription medication.
Amounts far in excess of the recommended dietary intake for vitamin functions will lower blood triglycerides and low density lipoprotein cholesterol (LDL-C), and raise blood high density lipoprotein cholesterol (HDL-C, often referred to as "good" cholesterol).
There are two forms: immediate-release and sustained-release Nicotinic acid.
Initial prescription amounts are 500 mg/day, increased over time until a therapeutic effect is achieved.
Immediate-release doses can be as high as 3,000 mg/day; sustained-release as high as 2,000 mg/day.
Despite the proven lipid changes, Nicotinic acid has not been found useful for decreasing the risk of cardiovascular disease in those already on a statin.
Nicotinic acid, on the other hand, is quite scarce in food and only recently started being sold as a supplement.
All three forms of vitamin B3 are converted to an important coenzyme called Nicotinic acid in the body.
Nicotinic acid is found in all living cells, and it plays a vital role in energy metabolism and maintaining proper cell functioning — particularly the functioning of our mitochondria, the power plants in our cells that turn food and oxygen into energy.
Nicotinic acid also plays an important role in protecting cells all over the body from age-related damage and decline in function.
While all three forms of vitamin B3 share common traits, each has a slightly different effect on the body and serves a different role when taken as a supplement.
Nicotinic acid (or nicotinic acid as it’s referred to in medical circles) was the third B vitamin to be discovered (hence the name B3).
Nicotinic acid wasn’t until about 1943, though, that a couple of doctors reported that niacin worked wonders in relieving the pain and stiffness associated with arthritis.
Nicotinic acid has a unique characteristic.
While not dangerous, Nicotinic acid can be uncomfortable, or even alarming, if you aren’t prepared for it.
Nicotinic acid, also known as vitamin B3, is a water-soluble vitamin.
Water-soluble vitamins are stored in the body in very limited amounts and are excreted through the urine.
Therefore, Nicotinic acid is a good idea to have them in your daily diet.
In addition to getting Nicotinic acid from dietary sources, the body can synthesize a form of niacin from the amino acid tryptophan.
Nicotinic acid causes the blood vessels to dilate or open up near the skin, which results in a hot, tingling sensation accompanied by a red flushing of the skin.
Generally, by starting with low amounts of Nicotinic acid (50 to 100 mg a day) and gradually increasing the dosage, a person can quickly build up a tolerance and avoid the flush.
Taking Nicotinic acid immediately following a meal will also lessen the flushing sensation.
Since Nicotinic acid isn’t something that drug companies can patent, it’s of little interest to them.
In fact, Nicotinic acid and niacinamide work on different circulatory systems and have their own unique benefits, making it important to take both.
Nicotinic acid in hydrochloric acid is highly suitable for checking the photometric accuracy of spectrometers in the UV range.
The Nicotinic acid spectrum shows a relatively broad maximum at the wavelengths 213 nm and 261 nm.
The Nicotinic acid filter solutions are filled and immediately fused under controlled conditions to become permanently airtight.
Nicotinic acid (NYE a sin) is used in combination with a healthy diet to lower bad cholesterol and increase good cholesterol.
Nicotinic acid is also used to decrease triglycerides.
Nicotinic acid can also be helpful in patients who have heart disease or who have had a heart attack.
Nicotinic acid may be used for other purposes; ask your health care provider or pharmacist if you have questions.
Nicotinic acid (also known as “vitamin B3” or “vitamin PP”) includes two vitamers (nicotinic acid and nicotinamide) giving rise to the coenzymatic forms nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP).
The two coenzymes are required for oxidative reactions crucial for energy production, but they are also substrates for enzymes involved in non-redox signaling pathways, thus regulating biological functions, including gene expression, cell cycle progression, DNA repair and cell death.
Nicotinic acid, Niacin or B3 is a water-soluble vitamin.
Derivatives of NADH, NADPH, NAD and NAD+ are a vitamin that has been affected in terms of energy, nuclear acids, protein fats and production.
Nicotinic acid cannot be included in the term vitamin B3.
Early in the research on niacin, a nutritional niacin deficiency was identified as the cause of pellagra in humans, blacktongue in dogs, and certain forms of dermatosis in humans.
Nicotinic acid deficiency is also associated with perosis in chickens as well as poor feathering of the birds.
Nicotinic acid can produce a variety of adverse effects, depending on the intake and health of the consumer.
The skin flushing reaction produced by nicotinic acid has been recognized for more than 70 years.
Nicotinic acid, melting point is 234-237℃.
Nicotinic acid is slightly soluble in water and ethanol; 100ml room temperature water can dissolve 1.6g.
When taken on an empty stomach, crystalline nicotinic acid in doses as small as 10 mg may produce a mild and transient, but noticeable, flushing reaction.
While not desirable, such reactions produce no known adverse consequences, and they are almost never perceptible when small amounts of nicotinic acid are taken in tablet or capsule form or consumed as part of food.
Nicotinic acid, also known as niacin or vitamin B3, is a white crystal or crystalline powder, odorless or has a slight odor, slight sour taste.
Nicotinic acid is easily soluble in hot water, hot ethanol, alkaline water, propylene glycol, and chloroform.
Nicotinic acid is amphoteric and forms salts with acids as well as bases.
Melting point: 236-239 °C(lit.)
Boiling point: 260C
Density: 1.473
refractive index: 1.5423 (estimate)
Flash point: 193°C
storage temp.: 2-8°C
solubility: 18g/l
pka: 4.85(at 25℃)
form: Powder
color: White to off-white
PH: 2.7 (18g/l, H2O, 20℃)
Odor: odorless to sl. odor, sour taste
Water Solubility: 1-5 g/100 mL at 17 ºC
Merck: 14,6525
BRN: 109591
BCS Class: 3
Stability: Stable. Incompatible with strong oxidizing agents. May be light sensitive.
InChIKey: PVNIIMVLHYAWGP-UHFFFAOYSA-N
LogP: 0.360
Nicotinic acid, also called nicotinic acid and vitamin B3, water-soluble vitamin of the B complex.
Nicotinic acid is also called the pellagra-preventive vitamin because an adequate amount in the diet prevents pellagra, a chronic disease characterized by skin lesions, gastrointestinal disturbance, and nervous symptoms.
Nicotinic acid is interchangeable in metabolism with its amide, niacinamide (nicotinamide).
Like the vitamins thiamin (vitamin B1) and riboflavin (vitamin B2), niacin functions as part of a coenzyme involved in the metabolism of carbohydrates and acts to catalyze the oxidation of sugar derivatives and other substances.
Nicotinic acid, which was identified as a pellagra preventive in 1937, is widely distributed among plants and animals.
Nicotinic acid approximately 15 mg per day (1 mg = 0.001 gram) of nicotinic acid is required by humans.
In the intestinal tract, the Nicotinic acid tryptophan can be converted to niacin by bacterial action and thus can serve as a source for part of the required Nicotinic acid.
This explains scientists’ early observation that the protein in such foods as eggs and milk, both poor sources of niacin, can nevertheless prevent or cure pellagra.
Nicotinic acid is indicated to prevent vitamin deficiencies in pediatric and adult patients receiving parenteral nutrition as part of multivitamin intravenous injections.
Nicotinic acid oral tablets are indicated as a monotherapy or in combination with simvastatin or lovastatin to treat primary hyperlipidemia and mixed dyslipidemia
Nicotinic acid can also be used to reduce the risk of nonfatal myocardial infarctions in patients with a history of myocardial infarction and hyperlipidemia.
Nicotinic acid is also indicated with bile acid binding resins to treat atherosclerosis in patients with coronary artery disease and hyperlipidemia or to treat primary hyperlipidemia.
Finally Nicotinic acid is indicated to treat severe hypertriglyceridemia.
Nicotinic acid is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Nicotinic acid acts to decrease levels of very low density lipoproteins and low density lipoproteins, while increasing levels of high density lipoproteins.
Nicotinic acid can be converted to nicotinamide in the animal body and, in this form, is found as a component of two oxidation-reduction coenzymes, NAD and NADP.
The nicotinamide portion of the coenzyme transfers hydrogens by alternating between an oxidized quaternary nitrogen and a reduced tertiary nitrogen.
Enzymes that contain Nicotinic acid or NADP are usually called dehydrogenases.
They participate in many biochemical reactions of lipid, carbohydrate, and protein metabolism.
An example of an Nicotinic acid-requiring system is lactic dehydrogenase which catalyzes the conversion of lactic acid to pyruvic acid.
Nicotinic acid decreases formation and secretion of VLDL by the liver.
This action appears secondary to its ability to inhibit fatty acid mobilization from adipose tissue.
Circulating free fatty acids provide the main source of fatty acids for hepatic triglyceride synthesis, and lowering triglyceride synthesis lowers Nicotinic acid formation and secretion by the liver.
Since plasma VLDL is the source of Nicotinic acid, lowering VLDL can ultimately lower LDL.
In addition, nicotinic acid shifts LDL particles to larger (more buoyant) sizes.
The larger LDL particles are thought to be less atherogenic.
Nicotinic acid can also significantly increase plasma HDL levels; the mechanism is unknown.
Nicotinic acid is also known as vitamin B3, one of the B-complex vitamins.
Vitamins help to support the body's ability to make and break down natural compounds (metabolism) needed for good health.
Nicotinic acid (nicotinamide) is a different form of vitamin B3 and does not work the same as niacin.
Nicotinic acid is both a vitamin, i.e., an essential nutrient, marketed as a dietary supplement, and in the US, a prescription medicine.
As a Nicotinic acid, it is precursor of the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP).
Severe deficiency of Nicotinic acid in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death.
Common psychiatric symptoms include irritability, poor concentration, anxiety, fatigue, loss of memory, restlessness, apathy, and depression.
Nicotinic acid is taken by mouth for high cholesterol and other fats.
Nicotinic acid is also used for low levels of a specific type of cholesterol, HDL.
Nicotinic acid is also used along with other treatments for circulation problems, migraine headache, Meniere's syndrome and other causes of dizziness, and to reduce the diarrhea associated with cholera.
Nicotinic acid is also taken by mouth to for preventing positive urine drug screens in people who take illegal drugs.
Nicotinic acid is taken by mouth for preventing vitamin B3 deficiency and related conditions such as pellagra.
Nicotinic acid is also taken by mouth for schizophrenia, hallucinations due to drugs, Alzheimer's disease and age-related loss of thinking skills, chronic brain syndrome, muscle spasms, depression, motion sickness, alcohol dependence, blood vessel swelling linked with skin lesions, and fluid collection (edema).
Some people take Nicotinic acid by mouth for acne, leprosy, attention deficit-hyperactivity disorder (ADHD), preventing premenstrual headache, improving digestion, protecting against toxins and pollutants, reducing the effects of aging, arthritis, lowering blood pressure, improving circulation, promoting relaxation, improving orgasms, and preventing cataracts.
Nicotinic acid is also used to improve exercise performance.
Nicotinic acid is a water-soluble vitamin that cannot be stored in body fat.
Nicotinic acid has two active components, nicotinic acid (niacin) and nicotinamide (niacinamide).
This vitamin plays a role in over 200 enzymatic reactions.
The body can synthesize Nicotinic acid in small amounts, provided it has sufficient stores of magnesium, vitamins B6 and B2, and tryptophan.
The latter is an essential amino acid (part of a protein)—that is, it is not produced by the body and must be obtained from food sources.
Nicotinic acid is a member of the B family of vitamins (B complex).
Nicotinic acida water-soluble vitamin.
Like the other B vitamins, Nicotinic acid helps make energy in your body.
Nicotinic acid helps your body use carbohydrates, fatty acids, and proteins.
Nicotinic acid is found in many plant and animal foods, such as yeast, meats (especially liver), grains, legumes, corn treated with alkali (such as corn used in tortillas), and seeds.
Nicotinic acid can be made by the liver from the amino acid tryptophan.
Nicotinic acid can be manufactured by plants and animals from the amino acid tryptophan.
Nicotinic acid is obtained in the diet from a variety of whole and processed foods, with highest contents in fortified packaged foods, meat, poultry, red fish such as tuna and salmon, lesser amounts in nuts, legumes and seeds.
Nicotinic acid as a dietary supplement is used to treat pellagra, a disease caused by niacin deficiency.
Signs and symptoms of pellagra include skin and mouth lesions, anemia, headaches, and tiredness many countries mandate its addition to wheat flour or other food grains, thereby reducing the risk of pellagra.
The amide derivative Nicotinic acid (niacinamide) is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP+).
Nicotinic acid, 3-pyridinecarboxylicacid (Niacin), is effective in the treatment of all types ofhyperlipoproteinemia except type I, at doses above thosegiven as a vitamin supplement.
Nicotinic acid reduces VLDLsynthesis and, subsequently, its plasma products, IDL andLDL.
Plasma triglyceride levels are reduced because of thedecreased VLDL production.
Cholesterol levels are lowered,in turn, because of the decreased rate of LDL formationfrom VLDL.
Although niacin is the drug of choicefor type II hyperlipoproteinemias, Nicotinic acids use is limited becauseof the vasodilating side effects.
Flushing occurs inpractically all patients but generally subsides when thedrug is discontinued.
The hypolipidemic effects of Nicotinic acid may be caused byits ability to inhibit lipolysis (i.e., prevent the release ofFFAs and glycerol from fatty tissues).
Therefore, there is areduced reserve of FFA in the liver and diminution oflipoprotein biosynthesis, which reduces the production ofVLDL.
The decreased formation of lipoproteins leads to apool of unused cholesterol normally incorporated inVLDL.
Nicotinic acid excess cholesterol is then excreted throughthe biliary tract.
Nicotinic acid, also known as B3, nicotinic acid or nicotinamide, is an important enzymatic component required for the body to function normally.
This vitamin allows us to obtain energy from macronutrients (carbohydrates and fats).
Nicotinic acid, a very important micronutrient for energy synthesis, also contributes to the healthy functioning of the nervous and digestive systems.
In addition to these, Nicotinic acid is known that it is good for skin health and vitality, hair and eyes.
Nicotinic acid, an enzymatic component, has an important role in the metabolism of fats and sugars.
In this way, cells have the ability to provide the energy they need to continue their normal functions.
Nicotinic acid use of supplements containing niacin may be beneficial in terms of weight loss, as the substance will stimulate energy synthesis and help reduce the feeling of fatigue caused by weight loss.
Nicotinic acid also positively affects the vitality and health of the skin, eyes and hair and can be used for the treatment of skin conditions such as dermatitis, skin irritation and acne.
Adequate consumption of niacin contributes to the strengthening of the digestive and immune systems, while helping to fight oxidative stress.
Nicotinic acid also has positive effects on the health of the nervous system (it triggers units related to cognitive functions and memory).
Nicotinic acid deficiency can cause serious symptoms such as muscle weakness, digestive upsets (irritation of the mucus layer in the mouth, stomach, and intestines), loss of appetite, and skin rashes.
In more severe cases, Nicotinic acid can cause lesions in the central nervous system, leading to confusion and disorientation.
Studies have shown that Nicotinic acid can significantly lower cholesterol levels, but because the product is inexpensive, the pharmaceutical industry has not commercialized this supplement as a combined treatment for hypercholesteremia.
Since Nicotinic acid helps regulate fat and cholesterol levels, it can be used for the prevention or treatment of cardiovascular ailments.
Uses Of Nicotinic acid:
Nicotinic acid is used as a medication to help lower elevated levels of LDL (low-density lipoprotein) cholesterol and triglycerides in the blood while increasing HDL (high-density lipoprotein) cholesterol.
Nicotinic acid is often prescribed for individuals with high cholesterol or those at risk of heart disease.
Due to its cholesterol-lowering properties, nicotinic acid can be prescribed to reduce the risk of heart attacks and strokes in certain patients with cardiovascular disease.
Nicotinic acid is sometimes used to treat hyperlipidemia, a condition characterized by high levels of lipids (fats) in the blood.
Nicotinic acid can also be used to manage dyslipidemia, a condition involving abnormal lipid levels in the blood, including high LDL cholesterol and triglycerides.
In some cases, nicotinic acid may be used to improve blood circulation in people with certain vascular conditions, like intermittent claudication, a symptom of peripheral arterial disease.
Nicotinic acid is sometimes used topically or in skincare products to improve the health and appearance of the skin.
Nicotinic acid can help address issues like acne, dry skin, and skin aging.
Nicotinic acid has been used in the prevention of migraines, although its effectiveness can vary from person to person.
Some studies have suggested that niacin supplementation may help improve certain symptoms of schizophrenia when used in combination with other medications.
Nicotinic acid is involved in various metabolic processes in the brain and may play a role in maintaining cognitive function.
Some research has explored its potential in Alzheimer's disease and age-related cognitive decline, though results are inconclusive.
High-dose Nicotinic acid has been used in certain detoxification programs for individuals trying to eliminate traces of illicit drugs, particularly marijuana, from their system.
This approach is controversial and should only be done under medical supervision.
Nicotinic acid is a crucial component in the production of energy within cells. It helps convert food into energy and is involved in various metabolic pathways.
Nicotinic acid has been shown to lower levels of Lp(a) cholesterol, which is associated with an increased risk of cardiovascular disease.
Nicotinic acid can be used in specific cases to target elevated Lp(a) levels.
Nicotinic acid, a form of niacin, is used in skincare products to address various skin conditions, such as acne, rosacea, and hyperpigmentation.
Nicotinic acid can help improve the appearance and texture of the skin.
Nicotinic acid has anti-inflammatory properties and is used in skincare products to soothe and calm irritated skin.
Nicotinic acid may also help reduce redness associated with certain skin conditions.
In addition to treating pellagra caused by niacin deficiency, nicotinic acid can sometimes be used to alleviate pellagra-like conditions that may result from other medical conditions or medications.
Nicotinic acid is an important factor in delivering hydrogen and fighting pellagra in organisms; it helps maintain skin and nerve health and stimulate digestion.
Nicotinic acid or niacinamide are used to treat and prevent pellagra.
This is a disease caused by niacin deficiency.
Nicotinic acid is also used to treat high cholesterol.
In some cases, niacin taken with colestipol can work as well as colestipol and a statin medicine.
Nicotinic acid USP granular is used for food fortification, as dietary supplement and as an intermediate of pharmaceuticals.
Nicotinic acid feed grade is used as vitamin for poultry, swines, ruminants, fish, dogs and cats, etc.
Nicotinic acid is also used as intermediate for nicotinic acid derivatives and technical applications.
Nicotinic acid is used to prevent and treat niacin deficiency (pellagra).
Nicotinic acid deficiency may result from certain medical conditions (such as alcohol abuse, malabsorption syndrome, Hartnup disease), poor diet, or long-term use of certain medications (such as isoniazid).
Nicotinic acid deficiency can cause diarrhea, confusion (dementia), tongue redness/swelling, and peeling red skin.
Nicotinic acid is also known as niacin and vitamin B3.
Nicotinic acid is a water-soluble conditioning agent that improves rough, dry, or flaky skin, helping smooth the skin and improve its suppleness.
Nicotinic acid enhances the appearance and feel of hair, by increasing body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.
When used in the formulation of skin care products, niacinamide and niacin enhance the appearance of dry or damaged skin by reducing flaking and restoring suppleness.
Nicotinic acid is a precursor of the coenzymes NAD and NADP.
Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains.
Nicotinic acid is a water-soluble b-complex vitamin that is necessary for the growth and health of tissues.
Dietary deficiency is associated with pellagra.
Nicotinic acid was functions as a nutrient and dietary supplement that prevents pellagra.
The term "Nicotinic acid" has also been applied.
The term “Nicotinic acid” has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid.
Nicotinic acid is essential for the proper functioning of the body, and a deficiency can lead to a condition called pellagra.
Supplementing with niacin can effectively treat and prevent pellagra.
Safety Profile Of Nicotinic acid:
Nicotinic acid, questionable carcinogen with experimental carcinogenic data.
When heated to decomposition it emits toxic fumes of NOx.
Nicotinic acid poison by intraperitoneal route.
Moderately toxic by ingestion, intravenous, and subcutaneous routes.
Human systemic effects: change in clotting factors, changes in platelet count.
