NONYL PHENOL 40

NONYL PHENOL 40 = NP 40 = NONOXYNOL-40

CAS Number: 127087-87-0
EC Number: 500-315-8
MDL Number: MFCD00132411
Chemical Formula: C15H24O(C2H4O)x

White to off white waxy solid /Flakes
Nonyl phenol 40 is highly water-soluble emulsifier & stabilizer Wetting. 
Nonyl phenol 40 is soluble in chlorinated solvents and polar solvents.

Chemically stable in the presence of dilute acids, bases and salts
Compatible with soaps, anionic and other nonionic surfactants, and many organic solvents
Nonyl phenol 40 are nonionic surfactants which are such as all kinds of other nonionic surfactants mixtures varying in the number of repeating ethoxy groups. 

The digit which is appeared after the name of phenol shows the average number of carbon-tail units in the Nonylphenol molecule. 
For example, Nonyl phenol 40 means a nonylphenol molecule which is reacted with average forty molecules of ethylene oxide.
A thick, yellowish liquid with a slight phenolic odor. 
Insoluble in water. 
Flash point 285°F. 

Nonyl phenol 40 is a non-ionic surfactant belonging to the group of ethoxylated nonylphenols. 
Nonyl phenol 40 is a white to light straw-coloured wax which solidifies at a temperature of about 35°C. 
Nonyl phenol 40 has good water solubility. 
Nonyl phenol 40 has a cloud point in the temperature range of 72-76°C in a solution of NaCl 100 g/L. 

Nonyl phenol 40 is a component of washing and cleaning agents and laundry detergents. 
Nonyl phenol 40 acts as an emulsifier and dispersant, thus improving detergency properties. 
Nonyl phenol 40 can be used in a mixture with other non-ionic auxiliaries and anionic and cationic agents. 
Nonyl phenol 40 is characterized by good resistance to oxidizing and reducing factors, as well as stability in acids and alkalis.

Nonyl phenol is a family of closely related organic compounds called alkylphenols. 
Alkylphenols are used in the production of antioxidants, lubricating oil additives, laundry and dishwashing detergents, emulsifiers and solubilizers. 
These compounds are also present in nonionic surfactants such as alkylphenol ethoxylates and nonylphenol ethoxylates used in detergents, paints, pesticides, personal care products and plastics.

Nonyl phenol 40 has attracted attention for Nonyl phenol 40's potential role as an endocrine disruptor and xenoestrogen due to its prevalence in the environment and its ability to act with estrogen-like activity. 
Nonyl phenol 40 is a commercially available detergent. 
Nonyl phenol 40 is an ethoxylated nonylphenol for non-ionic surfactants and can act as emulsifier and demulsifier agent.

Nonyl phenol 40 fall into the general chemical category of alkylphenols. 
The structure of Nonyl phenols can vary. 
The nonyl group can be attached to the phenol ring at various positions, usually the 4- and to a lesser extent 2-positions, and may be branched or linear. 

A branched nonylphenol, 4-nonylphenol, is the most widely produced and marketed nonylphenol. 
The mixture of nonylphenol isomers is a pale yellow liquid, but pure compounds are colorless. 
Nonylphenols are moderately soluble in water but soluble in alcohol.
Nonylphenol originates from the environmental degradation of nonylphenol ethoxylates, which are metabolites in commercial detergents called alkylphenol ethoxylates. 

NPEs are a clear to light orange colored liquid. 
Nonylphenol ethoxylates are non-ionic in water; this means they have no payload. 
Because of this property, they are used as detergents, cleaners, emulsifiers and various applications. 
They are amphipathic, meaning they have hydrophilic and hydrophobic properties; this allows them to surround non-polar substances such as oil and grease and insulate them from water.

USES and APPLICATIONS of NONYL PHENOL 40:
-Nonyl phenol 40 is used in manufacturing antioxidants, lubricating oil additives, laundry and dish detergents, emulsifiers, and solubilizers.
-Nonyl phenol 40 is used in the process for the manufacture of 5-nonyl salicylaldoxime, which is used for the selective purification and concentration of copper ions.

-Nonionic surfactant for use in paper and textile processing, paints & coatings, and agrochemicals; featuring versatile solubility characteristics, high water solubility, suitability for use at higher temperatures.
-Bituminous emulsions.
-Cleaners & detergents

-Nonyl phenol 40 is a non-ionic emulsifier in the emulsion polymerization process. 
-Nonyl phenol 40 is compatible with a wide range of polymers and can be used in the production of acrylic, styrene-acrylic, homo- and vinyl acetate copolymers. 
Typical application of Nonyl phenol 40 is 0.5-3% by weight of the total dispersion.

-Nonyl phenol 40 is also used as an emulsifier for the production of bituminous masses and for the emulsification of asphalts. 
-Nonyl phenol 40 is also an emulsifying additive in the production of polyester resins.
-Nonyl phenol 40 is used in the manufacture of oil additives, surfactants, fungicide preparations and plastics and rubber.
-Paper & textile processing

-Paints & coatings
-Agro-chemicals
-Metalworking fluids
-Nonyl phenol 40 is often used to break open all membranes within a cell, including the nuclear membrane. 

-Nonyl phenol 40 has applications in paper and textile processing, in paints and coatings, and in agrochemical manufacturing.
-Nonyl phenol 40 is a high active nonionic surfactant finding application in a variety of agricultural applications, detergents, sanitizers, industrial cleaners, metal cleaners, textiles, and paper deinking.
-Nonyl phenol 40 is nonionic and provides excellent detergency, outstanding wetting, versatile solubility characteristics and low odor. 

-Nonyl phenol 40 is used in paper & textile processing, paints & coatings and agrochemicals.
-Nonyl phenol 40 is used by various industries, such as Oil & Gas, Crop Solutions and Home Care and I&I, and act as wetting agents, solubilizers, detergents, dispersants, emulsifiers, and degreasers.
-Nonyl phenol 40 is a nonionic surfactant used in the isolation of membrane complexes. 

-Due to Nonyl phenol 40's nonionic structure, Nonyl phenol 40 is compatible with anionic surfactants and is stable in the presence of acids, bases, and salts. 
-Paints and coatings
-Emulsion polymerization
-Cleaners & degreasers
-Agrochemical

-Paints and coatings, paper and textile processing, cleaners and detergents, agrochemicals, and metalworking fluids, oilfield drilling and production formulations.
-Nonyl phenol 40 is used in a wide variety of applications, for instance detergent formulations, emulsifiers in many industries, paints and coatings, emulsion polymerization, and many others. 

-Nonyl phenol 40 is used anywhere there is a need for increased surface activity, and provide excellent all-purpose detergency and wetting, as well as solubilization and emulsification.
-Nonyl phenol 40 is important in the production of laundry detergents.
-Oil in water emulsion

-Metalworking fluid
-Paint & coatings
-Textiles,
-Nonyl phenol 40 is a high active nonionic surfactant finding application in a variety of agricultural applications, detergents, sanitizers, industrial cleaners, metal cleaners, textile applications, and paper deinking.

-Nonyl phenol 40 is used as cleaners & detergents, degreasers, paper & textile processing, paints, prewash spotters, agrochemicals, metalworking fluids, oil field chemicals. 
-Nonyl phenol 40 is used as emulsifier & detergent for textile, paint, agrochemicals, cleaners formulation
-Nonyl phenol 40 is used in the production of antioxidants, lubricating oil additives, laundry and dishwashing detergents, emulsifiers and solubilizers.

-Nonyl phenol 40 can also be used to produce tris (4-nonyl-phenyl) phosphide (TNPP), an antioxidant used to protect polymers such as rubber, vinyl polymers, polyolefins and polystyrene.
-Nonyl phenol 40 is a stabilizer in plastic food packaging. 
-Tanning,
-Metalworking,

-Pulp and paper industry,
-Industrial cleaning,
-Hard Surface Cleaners
-Oil Well Drilling Fluids
-Textile

-Alkaline Cleaner
-Cleaning Compounds
-Deinking Paper
-Degreaser
-Disinfectant Cleaners

-Cleaners
-Paint, Coatings
-Solubilizing Agent
-Cleaning product formulations
-Nonyl phenol 40 is used in many epoxy formulations.

-Nonionic surfactant for use in paints and coatings, paper and textile processing, cleaners and detergents, agrochemicals, and metalworking fluids.
-Excellent detergency, outstanding wetting, versatile solubility characteristics, and exceptional handling properties. 
-Nonyl phenol 40 can also be used in oilfield drilling and production formulations.

-Anywhere there is a need for increased surface activity.
-Nonyl phenol 40 is used as emulsifier, washing agent, wetting agent, penetrating agent, dispersing agent, degreasing agent, refining agent and chemical intermediate in the industry.

-Dispersant
-Glass Cleaners
-Metal Cleaners
-Steam Cleaner
-Agricultural Emulsifier

-Nonyl phenol 40 is suggested for use in cleaners & degreasers, prewash spotters and metalworking fluids.
-Nonyl phenol 40 is used in manufacturing antioxidants, lubricating oil additives, laundry and dish detergents, emulsifiers, and solubilizers.
-Nonyl phenol 40 can also be used to produce tris(4-nonyl-phenyl) phosphite (TNPP), which is an antioxidant used to protect polymers, such as rubber, Vinyl polymers, polyolefins, and polystyrenics in addition to being a stabilizer in plastic food packaging. 

-Nonyl phenol 40 is also used as heat stabilizers for polyvinyl chloride (PVC).
-Nonyl phenol 40 is also often used an intermediate in the manufacture of the non-ionic surfactants nonylphenol exthoxylates, which are used in detergents, paints, pesticides, personal care products, and plastics. 
-Nonyl phenol 40 is used as components of household detergents.

-Car Wash Soap
-Dairy Cleaners
-Detergents
-Textile
-Sanitizers

-Nonyl phenol 40 is used as heat stabilizers for polyvinyl chloride (PVC).
-Nonyl phenol 40 has been widely used as an intermediate in the production of nonionic surfactants of the nonylphenol ethoxylate (NPE) type. 
-Nonyl phenol 40 are used as oil-soluble detergents and emulsifiers, lubricants, oil additives, and antioxidants for rubber manufacture. 

-Nonyl phenol 40 is an alkylphenol  which is widely used as non-ionic surfactants, nonylphenol ethoxylate (NPEO) and octylphenol ethoxylate being the main representatives of this group. 
-Nonyl phenol 40 can be used in emulsifying applications.

-Nonyl phenol 40 is a non-ionic surfactant which belongs to the group of ethoxylated nonylphenols. 
-Nonyl phenol 40 is used as a detergent, washing and cleaning agent and as an emulsifier. 
-Acid Cleaners
-Penetrant

-Concrete Cleaners
-Dispersant
-Nonyl phenol 40 is used as a wetting agent and emulsifier in emulsion polymerization, drilling and production.
-Excellent oil-soluble surfactant, low HLB emulsifier.
-Cleaners & degreasers, dry cleaning

-Excellent emulsifier, wetting agent, stabilizer, couples detergent
range nonionics into hydrocarbon systems.
-Cleaners, degreasers, dry cleaning, adhesives, agrochemicals
-Nonyl phenol 40 is used in a wide variety of applications, for instance detergent formulations, emulsifiers in many industries, paints and coatings, emulsion polymerization, and many others. 

-Nonyl phenol 40 is used anywhere there is a need for increased
surface activity, and provide excellent all-purpose detergency and wetting, as well as solubilization and emulsification.
-Excellent detergency, outstanding wetting, good rinseability.
-Nonyl phenol 40 is suggested for use in paper & textile processing, paints & coatings and agrochemicals.

-Cleaners & detergents, paper & textile processing, laundry, paints & coatings, dust control, agrochemicals, metalworking fluids
-Excellent detergency, outstanding wetting, versatile solubility
characteristics, and exceptional handling properties.

ADVANTAGES of NONYL PHENOL 40:
-Non-ionic emulsifier in emulsion polymerization,
-Efficiently interacts with the anionic surfactant and controls the emulsion polymerization reaction parameters,
-Improves the stability of polymer dispersion,
-Compatible with a wide range of polymers,
-Good resistance to electrolytes.

-Oustanding wetting
-Effective at high temperatures
-Highly water-soluble emulsifier & stabilizer
-Versatile solubility characteristics
-Low odor
-Excellent detergency

BENEFITS of NONYL PHENOL 40:
-Effective at high temperatures
-Highly water-soluble emulsifier & stabilizer
-Wetting

-Versatile solubility characteristics
-Low odor
-Detergency

-Deliver a combination of economy and performance
-Excellent detergency and wetting
-Good solubilization and emulsification

NONYL PHENOLS:
Nonyl phenols, from the Latin nōnus (number 9) and phenol, are a family of closely related organic compounds composed of phenol bearing a 9 carbon-tail. 
Nonyl phenols can come in numerous structures, all of which may be considered alkylphenols. 
Nonyl phenols are used in manufacturing antioxidants, lubricating oil additives, laundry and dish detergents, emulsifiers, and solubilizers.

Nonyl phenols are also precursors to the commercially important non-ionic surfactants alkylphenol ethoxylates and nonylphenol ethoxylates, which are used in detergents, paints, pesticides, personal care products, and plastics. 
Nonyl phenol has attracted attention due to its prevalence in the environment and its potential role as an endocrine disruptor and xenoestrogen, due to its ability to act with estrogen-like activity.

The estrogenicity and biodegradation heavily depends on the branching of the nonyl sidechain.
Nonylphenol has been found to act as an agonist of the GPER (GPR30).
Nonylphenols fall into the general chemical category of alkylphenols.

The structure of NPs may vary. 
The nonyl group can be attached to the phenol ring at various locations, usually the 4- and, to lesser extent, the 2-positions, and can be either branched or linear. 
A branched nonylphenol, 4-nonylphenol, is the most widely produced and marketed nonylphenol.

The mixture of nonylphenol isomers is a pale yellow liquid, although the pure compounds are colorless. 
The nonylphenols are moderately soluble in water but soluble in alcohol.
Nonyl phenol arises from the environmental degradation of nonylphenol ethoxylates, which are the metabolites of commercial detergents called alkylphenol ethoxylates. 

Nonyl phenol ethoxylates are a clear to light orange color liquid. 
Nonylphenol ethoxylates are nonionic in water, which means that they have no charge. 
Because of this property they are used as detergents, cleaners, emulsifiers, and a variety of other applications. 

They are amphipathic, meaning they have both hydrophilic and hydrophobic properties, which allows them to surround non-polar substances like oil and grease, isolating them from water.
Nonylphenol persists in aquatic environments and is moderately bioaccumulative. 
It is not readily biodegradable, and it can take months or longer to degrade in surface waters, soils, and sediments. 

Nonbiological degradation is negligible. 
In sewage treatment plants, nonylphenol ethoxylate degrades into nonylphenol, which is found in river water and sediments as well as soil and groundwater.
Nonylphenol photodegrades in sunlight, but its half-life in sediment is estimated to be more than 60 years. 
Although the concentration of nonylphenol in the environment is decreasing, it is still found at concentrations of 4.1 μg/L in river waters and 1 mg/kg in sediments.
Nonylphenol is not persistent in air, as it is rapidly degraded by hydroxyl radicals.

PRODUCTION of NONYL PHENOLS:
Nonylphenol can be produced industrially, naturally, and by the environmental degradation of alkylphenol ethoxylates. 
Industrially, nonylphenols are produced by the acid-catalyzed alkylation of phenol with a mixture of nonenes. 
This synthesis leads to a very complex mixture with diverse nonylphenols.

Theoretically there are 211 constitutional isomers and this number rise to 550 isomers if we take the enantiomers into account.
To make NPEs, manufacturers treat NP with ethylene oxide under basic conditions.
Since its discovery in 1940, nonylphenol production has increased exponentially, and between 100 and 500 million pounds of nonylphenol are produced globally every year, meeting the definition of High Production Volume Chemicals.

Nonylphenols are also produced naturally in the environment. 
One organism, the velvet worm, produces nonylphenol as a component of its defensive slime. 
The nonylphenol coats the ejection channel of the slime, stopping it from sticking to the organism when it is secreted. 
It also prolongs the drying process long enough for the slime to reach its target.
Another surfactant called nonoxynol, which was once used as intravaginal spermicide and condom lubricant, was found to metabolize into free nonylphenol when administered to lab animals.

PHYSICAL and CHEMICAL PROPERTIES of NONYL PHENOL 40:
Molecular Weight: 220.35
XLogP3: 5.9
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 8
Exact Mass: 220.182715385
Monoisotopic Mass: 220.182715385
Topological Polar Surface Area: 20.2 Ų
Heavy Atom Count: 16

Formal Charge: 0
Complexity: 148
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Appearance @ 20˚C: White Solid
Color:    Max. 50    
Viscosity @ 50˚C: ca. 220
Density @ 50˚C: 1.07±0.02g/cm3    
pH (5% in water): 5-7
HLB: 17.8
(1% in NaCl 10%): 76 – 80˚C
Hydroxyl value: 26 – 30    mgKOH/g
Water: Max. 0.5

Melting point: 43-44°C
Boiling point: 293-297 °C
Density: 0.937 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.511(lit.)
Flash point: >230 °F
Storage temp.: APPROX 20°C
Solubility: Sparingly Soluble (0.020 g/L) at 25°C.

Form: neat
pka: 6.15±0.15(Predicted)
Specific Gravity: ~1.057
Color: Clear colorless
Odor: Phenol like
PH Range: 6 - 8
Water Solubility: 6.35mg/L(25 ºC)

ΔfG°: 33.21 kJ/mol
ΔfH°gas: -293.71 kJ/mol
ΔfusH°: 34.43 kJ/mol
ΔvapH°: 64.27 kJ/mol
logPoct/wat: 4.685    
Pc: 2108.07 kPa
Tboil: 649.90 K
Tc: 851.69 K
Tfus: 396.95 K
Vc: 0.734 m3/kg-mol

FIRST AID MEASURES of NONYL PHENOL 40:
-General advice:
Consult a physician.

-If inhaled:
Fresh air.

-In case of skin contact:
Take off immediately all contaminated clothing. 
Rinse skin with water/ shower.

-In case of eye contact:
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.

-If swallowed:
Immediately make victim drink water (two glasses at most). 
Consult a physician.

-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of NONYL PHENOL 40:
-Personal precautions, protective equipment and emergency procedures:
*Advice for non-emergency personnel: 
Ensure adequate ventilation. 

-Environmental precautions:
Do not let product enter drains.

-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of NONYL PHENOL 40:
-Extinguishing media:
*Suitable extinguishing media:
Water Foam Carbon dioxide (CO2) Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

EXPOSURE CONTROLS/PERSONAL PROTECTION of NONYL PHENOL 40:
-Control parameters:
*Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:

*Eye/face protection:
Use safety glasses

*Body Protection:
Use protective clothing

-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of NONYL PHENOL 40:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.

-Specific end use(s):
No other specific uses are stipulated.

STABILITY and REACTIVITY of NONYL PHENOL 40:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .

SYNONYMS:
4-nonylphenol
4-n-Nonylphenol
p-Nonylphenol
para-Nonylphenol
p-n-Nonylphenol
Phenol, 4-nonyl-
4-nonyl phenol
Phenol, p-nonyl-
Nonylphenol (mixed)
Phenol, nonyl derivs.
para Nonyl phenol
4-Nonyl-Phenol
p -n -Nonylphenol
p-nonyl phenol
4-n-Nonyl phenol
DTXSID5033836
DSSTox_CID_1857
DSSTox_RID_79098
DSSTox_GSID_33836
4-NP
CCRIS 1251
HSDB 5359
BRN 2047450
paranonylphenol
nonyl-phenol
p-nonyl-phenol
Para-nonyl phenol
4-Nonylphenol, tech.
Spectrum_001973
SpecPlus_000624
P-NONYLPHENOL 
Spectrum2_001832
Spectrum5_002066
4-n-Nonylphenol, 85%
4-n-Nonylphenol, 98%
BIDD:PXR0002
SCHEMBL15887
BSPBio_002543
KBioGR_001263
KBioSS_002539
SPECTRUM330085
BIDD:ER0006
DivK1c_006720
SPBio_001903
CHEMBL153062
4-Nonylphenol-2,3,5,6-d4
KBio1_001664
KBio2_002530
KBio2_005098
KBio2_007666
KBio3_002043
4-Nonylphenol, analytical standard
ZINC1850497
Tox21_201241
LMPK15010001
STL453644
AKOS015888197
MCULE-5930378829
NCGC00090918-01
NCGC00090918-02
NCGC00090918-03
NCGC00090918-05
NCGC00090918-06NCGC00090918-07
NCGC00090918-08
NCGC00257420-01
NCGC00258793-01
FT-0619310
FT-0673035
4-n-Nonylphenol 10 microg/mL in Acetonitrile
4-n-Nonylphenol 10 microg/mL in Cyclohexane
4-n-Nonylphenol 100 microg/mL in Cyclohexane
4-Nonylphenol, PESTANAL(R), analytical standard
SR-05000002459
J-001167
Q4545806
SR-05000002459-1
4-Nonylphenol, certified reference material, TraceCERT(R)