Quick Search
Nonylphenol, ethoxylated (8-EO), also known as NPEs, are nonionic surfactants that are liquid in form.
Many different types of NPEs are determined by the number of moles of Nonylphenol, ethoxylated (8-EO), or EO.
Nonylphenol, ethoxylated (8-EO)'s may function as adjuvants, cleaners, detergents, dispersants, emulsifiers, humectants, solubilizers or wetting agents.
CAS: 9016-45-9
MF: C19H32O3
MW: 308.45558
EINECS: 500-024-6
Synonyms
NONIDET P- 40 SUBSTITUTE NP-40;NP-10(Nonylphenyl-polyethylene glycol solution);NP-12(Nonylphenyl-polyethylene glycol solution);NP-15(Nonylphenyl-polyethylene glycol solution);NP-20(Nonylphenyl-polyethylene glycol solution);NP-4(Nonylphenyl-polyethylene glycol solution);NP-40(Nonylphenyl-polyethylene glycol solution);NP-50(Nonylphenyl-polyethylene glycol solution)
Nonylphenol, ethoxylated (8-EO) is used in many applications, including coatings, crop solutions, functional fluids, household, industrial, and institutional cleaning, as well as oil and gas.
Nonylphenol, ethoxylated (8-EO) is a nonionic surfactant commonly used in various industrial and consumer applications.
Nonylphenol, ethoxylated (8-EO) is characterized by its hydrophilic polyethylene glycol (PEG) backbone and a hydrophobic nonylphenyl group, which imparts surfactant properties.
Nonylphenol, ethoxylated (8-EO) typically exhibits good solubility in both water and organic solvents, making it effective in emulsifying, wetting, and dispersing formulations.
Nonylphenol, ethoxylated (8-EO)'s molecular structure allows it to lower surface tension, enhancing the stability of emulsions and foams.
Nonylphenol, ethoxylated (8-EO) is often utilized in personal care products, detergents, and agricultural formulations due to its ability to improve the performance of active ingredients.
However, Nonylphenol, ethoxylated (8-EO) is important to note that nonylphenol, a degradation product of this ether, has raised environmental and health concerns, leading to regulatory scrutiny in some regions.
As a result, alternatives are being explored in formulations to mitigate potential ecological impacts.
Overall, Nonylphenol, ethoxylated (8-EO) is valued for its versatility and effectiveness in enhancing product performance across various applications.
Nonylphenol, ethoxylated (8-EO) Chemical Properties
Melting point: 44-46 °C
Boiling point: 250 °C(lit.)
density: 1.06 g/mL at 20 °C
vapor pressure: 1.4hPa at 25℃
refractive index: n20/D 1.495(lit.)
Fp: 535 °F
storage temp.: -20°C
form: Clear, colorless liquid
color: clear colorless
PH: 5-8 (5% in H2O)
biological source: rabbit
Water Solubility: water: 25mg/mL
aqueous buffer: soluble
Specific Activity: 613-829nmol/min·mg
Cosmetics Ingredients Functions SURFACTANT - SOLUBILIZING
SURFACTANT - EMULSIFYING
SURFACTANT - CLEANSING
Cosmetic Ingredient Review (CIR): Nonylphenol Ethoxylate (9016-45-9)
InChI: InChI=1S/C19H32O3/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)22-17-16-21-15-14-20/h10-13,20H,2-9,14-17H2,1H3
InChIKey: BLXVTZPGEOGTGG-UHFFFAOYSA-N
LogP: 3.7-4.48 at 25℃
Surface tension: 32.3mN/m at 1g/L and 20℃
CAS DataBase Reference: 9016-45-9
EPA Substance Registry System: Polyethylene glycol nonylphenyl ether (9016-45-9)
Uses
Nonylphenol, ethoxylated (8-EO) is suitable for the preparation of cell extracts to be analyzed by Antibody Bead Immunoassay (Luminex), ELISA, and Western blotting.
Nonylphenol, ethoxylated (8-EO) can also be used as a wash buffer for immunoprecipitation reactions.
Nonylphenol, ethoxylated (8-EO) is a nonionic surfactant that can be used for testing the stress cracking resistance of polyethylene materials at high temperatures.
Nonylphenol, ethoxylated (8-EO) is also suitable for enhancing the biodegradation of aromatic hydrocarbon compounds.
Biochem/physiol Actions
Nonylphenol, ethoxylated (8-EO) is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines.
Activation of Nonylphenol, ethoxylated (8-EO)requires both tyrosine and threonine phosphorylation that is mediated by MEK.
Nonylphenol, ethoxylated (8-EO) is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord.
Activated Nonylphenol, ethoxylated (8-EO) translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).
