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o-Chloro benzaldehyde is an aromatic aldehyde used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, and fragrances.
o-Chloro benzaldehyde belongs to the chloro-substituted benzaldehydes, offering both electrophilic reactivity from the aldehyde group and substitution reactivity from the chloro substituent.
o-Chloro benzaldehyde is valued in chemical industries for its versatility in forming heterocyclic compounds, fine chemicals, and specialty intermediates.
CAS Number: 89-98-5
EC Number: 201-944-0
Molecular Formula: C7H5ClO
Molecular Weight: 140.57 g/mol
Synonyms: o-Chloro benzaldehyde, 2-Chlorobenzaldehyde, ortho-Chloro benzaldehyde, Benzaldehyde, o-chloro-, 2-CBA, o-Chlorobenzal, 2-Chlorobenzal, Aldehyde o-chloro benzene, ortho-Chlorobenzaldehyde reagent, Chlorinated benzaldehyde 2-isomer, Intermediate 2-chlorobenzaldehyde, Pharmaceutical intermediate o-chloro benzaldehyde, Agrochemical intermediate 2-chlorobenzaldehyde, Fine chemical o-chlorobenzaldehyde, Fragrance intermediate o-chloro benzaldehyde
APPLICATIONS
o-Chloro benzaldehyde is used as an intermediate in the synthesis of pharmaceuticals.
o-Chloro benzaldehyde is employed in the preparation of active pharmaceutical ingredients (APIs).
o-Chloro benzaldehyde is applied in the development of antihypertensive and antimicrobial agents.
o-Chloro benzaldehyde is incorporated into agrochemical production.
o-Chloro benzaldehyde is used in the synthesis of fungicides and herbicides.
o-Chloro benzaldehyde is applied in insecticide intermediate formulations.
o-Chloro benzaldehyde is utilized in dye and pigment synthesis.
o-Chloro benzaldehyde is used to produce specialty azo and anthraquinone dyes.
o-Chloro benzaldehyde is incorporated into optical brighteners and textile intermediates.
o-Chloro benzaldehyde is employed in fragrance manufacturing.
o-Chloro benzaldehyde is used to create aromatic compounds with fresh and floral notes.
o-Chloro benzaldehyde is applied in fine fragrances and household products.
o-Chloro benzaldehyde is used in heterocyclic chemistry as a starting material.
o-Chloro benzaldehyde is applied in synthesizing benzoxazoles, benzothiazoles, and quinoline derivatives.
o-Chloro benzaldehyde is incorporated in research for drug discovery.
o-Chloro benzaldehyde is utilized in specialty resin production.
o-Chloro benzaldehyde is used in polymer chemistry as a reactive aldehyde intermediate.
o-Chloro benzaldehyde is applied in crosslinking agents for industrial polymers.
o-Chloro benzaldehyde is employed in laboratory research as a model aldehyde.
o-Chloro benzaldehyde is used in teaching organic synthesis involving aromatic aldehydes.
o-Chloro benzaldehyde is applied in analytical method development.
o-Chloro benzaldehyde is included in the synthesis of fine chemicals.
o-Chloro benzaldehyde is used in the development of specialty intermediates.
o-Chloro benzaldehyde is applied in the formulation of performance materials.
O-Chloro Benzaldehyde is used as an intermediate in the synthesis of pharmaceuticals.
O-Chloro Benzaldehyde is incorporated into the production of active pharmaceutical ingredients.
O-Chloro Benzaldehyde is applied in the preparation of antibacterial and antifungal agents.
O-Chloro Benzaldehyde is used in the manufacture of agrochemicals.
O-Chloro Benzaldehyde is incorporated into herbicide formulations as a building block.
O-Chloro Benzaldehyde is applied in insecticide synthesis for crop protection.
O-Chloro Benzaldehyde is used in the fragrance industry.
O-Chloro Benzaldehyde is incorporated into aromatic compounds to provide floral and spicy notes.
O-Chloro Benzaldehyde is applied in perfumery for synthetic fragrance blends.
O-Chloro Benzaldehyde is used as an intermediate in dye manufacturing.
O-Chloro Benzaldehyde is incorporated into the synthesis of azo dyes.
O-Chloro Benzaldehyde is applied in pigment production for vivid coloration.
O-Chloro Benzaldehyde is used in the polymer industry.
O-Chloro Benzaldehyde is incorporated into resin synthesis for specialized coatings.
O-Chloro Benzaldehyde is applied in polymer modification to impart chemical resistance.
O-Chloro Benzaldehyde is used in the preparation of fine chemicals.
O-Chloro Benzaldehyde is incorporated into laboratory research for organic synthesis.
O-Chloro Benzaldehyde is applied as a starting material for heterocyclic compounds.
O-Chloro Benzaldehyde is used in the synthesis of UV-absorbing compounds.
O-Chloro Benzaldehyde is incorporated into formulations to enhance photostability.
O-Chloro Benzaldehyde is applied in cosmetic formulations requiring UV protection.
O-Chloro Benzaldehyde is used in the development of corrosion inhibitors.
O-Chloro Benzaldehyde is incorporated into formulations for metal surface protection.
O-Chloro Benzaldehyde is applied in coatings to extend equipment lifespan.
O-Chloro Benzaldehyde is used in specialty chemical production.
O-Chloro Benzaldehyde is incorporated into research for novel materials.
O-Chloro Benzaldehyde is applied in advanced organic synthesis pathways.
O-Chloro Benzaldehyde is used in academic research as a model compound.
O-Chloro Benzaldehyde is incorporated into reaction mechanism studies.
O-Chloro Benzaldehyde is applied in teaching laboratories to illustrate aldehyde chemistry.
O-Chloro Benzaldehyde is used in the flavor and aroma industry in trace levels.
O-Chloro Benzaldehyde is incorporated into artificial flavoring experiments.
O-Chloro Benzaldehyde is applied in sensory research for aromatic aldehydes.
O-Chloro Benzaldehyde is used in specialty coatings for enhanced durability.
O-Chloro Benzaldehyde is incorporated into industrial lacquer formulations.
O-Chloro Benzaldehyde is applied in protective finishes for engineered products.
O-Chloro Benzaldehyde is used in synthesis of heteroaryl compounds.
O-Chloro Benzaldehyde is incorporated into medicinal chemistry workflows.
O-Chloro Benzaldehyde is applied in preclinical drug discovery research.
O-Chloro Benzaldehyde is used as a precursor for photoinitiators.
O-Chloro Benzaldehyde is incorporated into UV-curable resin technology.
O-Chloro Benzaldehyde is applied in 3D printing resins for improved curing efficiency.
DESCRIPTION
O-Chloro Benzaldehyde is an aromatic aldehyde derivative with a chlorine substituent on the ortho position of the benzene ring.
O-Chloro Benzaldehyde appears as a pale yellow to light brown liquid with a sharp odor.
O-Chloro Benzaldehyde is sparingly soluble in water but miscible with organic solvents such as ethanol and ether.
O-Chloro Benzaldehyde is chemically reactive, participating in condensation and substitution reactions.
O-Chloro Benzaldehyde is a versatile building block in pharmaceuticals, agrochemicals, and dyes.
O-Chloro Benzaldehyde exhibits moderate stability but should be stored away from heat and light.
O-Chloro Benzaldehyde can undergo oxidation reactions to form carboxylic acids.
O-Chloro Benzaldehyde is sensitive to strong bases and oxidizing agents.
O-Chloro Benzaldehyde is commonly produced by chlorination of benzaldehyde.
O-Chloro Benzaldehyde is widely used in chemical industries due to its reactivity and versatility.
o-Chloro benzaldehyde is a colorless to pale yellow liquid with a strong, pungent aromatic odor.
o-Chloro benzaldehyde is slightly soluble in water but soluble in most organic solvents such as ethanol and ether.
o-Chloro benzaldehyde is reactive due to the aldehyde functional group, undergoing oxidation, reduction, and condensation reactions.
o-Chloro benzaldehyde is stable under recommended storage conditions but oxidizes upon prolonged exposure to air and light.
o-Chloro benzaldehyde may form peroxides or polymeric byproducts if not properly stored.
o-Chloro benzaldehyde is considered hazardous and must be handled with care due to irritant properties.
o-Chloro benzaldehyde is volatile and flammable under normal conditions.
o-Chloro benzaldehyde is widely used as a chemical intermediate due to its dual functionality.
o-Chloro benzaldehyde is biodegradable but can cause aquatic toxicity in high concentrations.
o-Chloro benzaldehyde is regulated for safe handling in industrial and laboratory applications.
PROPERTIES
Chemical Formula: C7H5ClO
Molecular Weight: 140.57 g/mol
Common Name: o-Chloro benzaldehyde
Appearance: Colorless to pale yellow liquid
Odor: Strong, pungent aromatic odor
Density: ~1.24 g/cm³
Boiling Point: 210–212°C
Flash Point: ~87°C (closed cup)
Solubility: Slightly soluble in water; soluble in organic solvents
Reactivity: Reactive aldehyde; undergoes condensation, oxidation, and reduction
Chemical Stability: Stable under recommended storage; sensitive to light and air
Storage Temperature: Store at 5–25°C in tightly sealed containers, protected from sunlight
FIRST AID
Inhalation:
If o-Chloro benzaldehyde vapors are inhaled, move person to fresh air immediately.
Seek medical attention if coughing, dizziness, or respiratory distress occurs.
Provide oxygen if breathing difficulties arise.
Skin Contact:
Wash affected skin with soap and plenty of water.
Seek medical advice if redness, irritation, or burns occur.
Remove contaminated clothing and wash before reuse.
Eye Contact:
Rinse eyes with water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or pain persists.
Remove contact lenses if present and continue rinsing.
Ingestion:
If o-Chloro benzaldehyde is swallowed, rinse mouth thoroughly with water.
Do not induce vomiting unless directed by medical personnel.
Seek immediate medical attention.
Note to Physicians:
Treat symptomatically.
Monitor for respiratory tract and gastrointestinal irritation.
Provide supportive care.
HANDLING AND STORAGE
Handling:
Personal Protection:
Wear chemical-resistant gloves, goggles, and protective clothing when handling o-Chloro benzaldehyde.
Use respiratory protection if ventilation is insufficient.
Ventilation:
Ensure adequate local exhaust ventilation in handling areas.
Prevent accumulation of vapors.
Avoidance:
Avoid direct contact with skin, eyes, and clothing.
Do not eat, drink, or smoke during handling.
Wash hands thoroughly after use.
Spill and Leak Procedures:
Absorb spills with inert material (sand, vermiculite).
Collect in suitable containers for disposal according to local regulations.
Prevent entry into waterways or drains.
Storage:
Store o-Chloro benzaldehyde in a cool, dry, well-ventilated place.
Keep containers tightly closed and protected from light and air.
Avoid contact with strong oxidizing agents.
Handling Cautions:
Ground and bond containers when transferring liquid.
Store under inert atmosphere for long-term stability.
Prevent vapor buildup and ignition sources in storage areas.
