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Octenidine dihydrochloride is a cationic surfactant and antiseptic compound widely used in medical, pharmaceutical, and personal care applications.
Octenidine dihydrochloride is valued for its broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.
Octenidine dihydrochloride is considered a safe and effective alternative to older antiseptics such as chlorhexidine and is increasingly used in wound care and oral hygiene products.
CAS Number: 70775-75-6
EC Number: 274-861-8
Molecular Formula: C36H62N4O4·2HCl
Molecular Weight: 623.81 g/mol
Synonyms: Octenidine dihydrochloride, Octenidine HCl, Octenidine.2HCl, Octenidindihydrochlorid, Antiseptic octenidine dihydrochloride, Bis-(dihydropyridinyl)-decane dihydrochloride, Octenidine-based disinfectant, Cationic surfactant octenidine dihydrochloride, Medical antiseptic octenidine, Octenidine hydrochloride salt, Octenidine bis-hydrochloride, Pharmaceutical grade octenidine, Topical antiseptic octenidine dihydrochloride, Wound care active octenidine dihydrochloride
APPLICATIONS
Octenidine dihydrochloride is widely used in wound care solutions for disinfection of acute and chronic wounds.
Octenidine dihydrochloride is applied in antiseptic wound gels to prevent infection.
Octenidine dihydrochloride is used in surgical wound management for its antimicrobial properties.
Octenidine dihydrochloride is incorporated into oral rinses and mouthwashes for the prevention of gingivitis and periodontitis.
Octenidine dihydrochloride is applied in dental care to reduce plaque formation.
Octenidine dihydrochloride is used in oral sprays for maintaining oral hygiene.
Octenidine dihydrochloride is utilized in preoperative skin disinfection.
Octenidine dihydrochloride is applied in antiseptic wipes for skin preparation.
Octenidine dihydrochloride is used in surface disinfectants for medical devices.
Octenidine dihydrochloride is incorporated into catheter lock solutions to reduce infection risks.
Octenidine dihydrochloride is applied in vascular access care.
Octenidine dihydrochloride is used in urinary catheter hygiene.
Octenidine dihydrochloride is employed in dermatological formulations for acne treatment.
Octenidine dihydrochloride is applied in topical antiseptics for skin lesions.
Octenidine dihydrochloride is used in foot care products to control microbial growth.
Octenidine dihydrochloride is utilized in gynecological hygiene products for safe disinfection.
Octenidine dihydrochloride is applied in vaginal gels to prevent infections.
Octenidine dihydrochloride is included in intimate hygiene solutions.
Octenidine dihydrochloride is used in burn treatment to prevent secondary infections.
Octenidine dihydrochloride is applied in bandage-impregnated antiseptic layers.
Octenidine dihydrochloride is incorporated in hospital infection control protocols.
Octenidine dihydrochloride is employed in veterinary medicine as a disinfectant.
Octenidine dihydrochloride is applied in animal wound care formulations.
Octenidine dihydrochloride is used in livestock hygiene products.
Octenidine dihydrochloride is incorporated into hand sanitizers and antiseptic gels.
Octenidine dihydrochloride is applied in hospital-grade hand hygiene products.
Octenidine dihydrochloride is used in personal hygiene disinfectant sprays.
Octenidine dihydrochloride is employed in ophthalmic formulations for surface disinfection.
Octenidine dihydrochloride is applied in ear and nasal antiseptic solutions.
Octenidine dihydrochloride is used in mucosal antiseptic sprays.
Octenidine dihydrochloride is used as an antiseptic in wound care products.
Octenidine dihydrochloride is incorporated into solutions for cleaning acute and chronic wounds.
Octenidine dihydrochloride is applied in gels to support healing and prevent infections.
Octenidine dihydrochloride is used in oral care products.
Octenidine dihydrochloride is incorporated into mouth rinses to reduce oral bacteria.
Octenidine dihydrochloride is applied in dental care to manage gingivitis and periodontitis.
Octenidine dihydrochloride is used as a skin disinfectant before surgical procedures.
Octenidine dihydrochloride is incorporated into preoperative skin preparations.
Octenidine dihydrochloride is applied in hospital hygiene protocols for patient safety.
Octenidine dihydrochloride is used in mucous membrane antisepsis.
Octenidine dihydrochloride is incorporated into vaginal suppositories for infection control.
Octenidine dihydrochloride is applied in intimate hygiene products for antimicrobial protection.
Octenidine dihydrochloride is used in catheter care to reduce infection risk.
Octenidine dihydrochloride is incorporated into catheter coatings for antimicrobial activity.
Octenidine dihydrochloride is applied in urological care to prevent bacterial colonization.
Octenidine dihydrochloride is used in surgical hand disinfectants.
Octenidine dihydrochloride is incorporated into alcohol-based rubs for enhanced efficacy.
Octenidine dihydrochloride is applied in hospital settings to reduce microbial transmission.
Octenidine dihydrochloride is used in wound dressings with antimicrobial functionality.
Octenidine dihydrochloride is incorporated into hydrogel dressings to reduce infection.
Octenidine dihydrochloride is applied in foam dressings for long-lasting protection.
Octenidine dihydrochloride is used in dermatological products for acne treatment.
Octenidine dihydrochloride is incorporated into facial cleansers to reduce bacterial load.
Octenidine dihydrochloride is applied in lotions for irritated or compromised skin.
Octenidine dihydrochloride is used in veterinary medicine for animal wound care.
Octenidine dihydrochloride is incorporated into sprays for livestock hygiene.
Octenidine dihydrochloride is applied in companion animal care to support healing.
Octenidine dihydrochloride is used in disinfectant wipes for medical equipment.
Octenidine dihydrochloride is incorporated into surface cleaners in healthcare settings.
Octenidine dihydrochloride is applied in wipes for quick disinfection of devices.
Octenidine dihydrochloride is used in pharmaceutical formulations as a preservative.
Octenidine dihydrochloride is incorporated into topical preparations for microbial control.
Octenidine dihydrochloride is applied in ophthalmic solutions in low concentrations.
Octenidine dihydrochloride is used in intensive care units for patient antisepsis.
Octenidine dihydrochloride is incorporated into protocols for central line-associated infection prevention.
Octenidine dihydrochloride is applied in ICU hygiene regimens for high-risk patients.
Octenidine dihydrochloride is used in first-aid antiseptic sprays.
Octenidine dihydrochloride is incorporated into consumer wound care kits.
Octenidine dihydrochloride is applied for immediate infection control in cuts and abrasions.
Octenidine dihydrochloride is used in burn care formulations.
Octenidine dihydrochloride is incorporated into sprays for superficial burns.
Octenidine dihydrochloride is applied in gels for soothing and antimicrobial effects.
DESCRIPTION
Octenidine dihydrochloride is a cationic bispyridine compound with strong antimicrobial properties.
Octenidine dihydrochloride appears as a white to off-white crystalline powder.
Octenidine dihydrochloride is freely soluble in water and ethanol, forming clear solutions.
Octenidine dihydrochloride exhibits broad-spectrum activity against Gram-positive and Gram-negative bacteria.
Octenidine dihydrochloride also shows efficacy against fungi and some enveloped viruses.
Octenidine dihydrochloride is stable over a wide pH range, making it suitable for diverse formulations.
Octenidine dihydrochloride has low systemic absorption when applied topically, ensuring safety.
Octenidine dihydrochloride is valued as an alternative to chlorhexidine in sensitive patients.
Octenidine dihydrochloride is compatible with a variety of wound care and medical products.
Octenidine dihydrochloride is widely used in healthcare, dentistry, dermatology, and veterinary medicine.
Octenidine dihydrochloride is a white to off-white crystalline powder.
Octenidine dihydrochloride is odorless and has a neutral to slightly bitter taste.
Octenidine dihydrochloride is freely soluble in water, ethanol, and propylene glycol.
Octenidine dihydrochloride is a bispyridine derivative with dual cationic charges, enabling strong binding to microbial membranes.
Octenidine dihydrochloride disrupts cell membranes, leading to rapid antimicrobial action.
Octenidine dihydrochloride is highly effective at low concentrations, typically 0.05–0.1%.
Octenidine dihydrochloride exhibits stability across a wide pH range (5–9).
Octenidine dihydrochloride does not lead to significant resistance development compared to antibiotics.
Octenidine dihydrochloride is non-toxic at therapeutic concentrations and is well tolerated in topical use.
Octenidine dihydrochloride is considered environmentally safe due to its biodegradability.
PROPERTIES
Chemical Formula: C36H62N4O4·2HCl
Molecular Weight: 623.81 g/mol
Common Name: Octenidine dihydrochloride
Appearance: White to off-white crystalline powder
Odor: Odorless
Density: Approx. 1.2 g/cm³
Melting Point: ~240°C (decomposes)
Solubility: Freely soluble in water, ethanol, propylene glycol
Reactivity: Strong cationic surfactant with membrane-disrupting activity
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store at 15–25°C in tightly closed containers, protected from moisture
FIRST AID
Inhalation:
If Octenidine dihydrochloride dust is inhaled, move person to fresh air immediately.
Seek medical attention if respiratory irritation occurs.
Provide artificial respiration if breathing stops.
Skin Contact:
Wash affected skin with soap and water.
Seek medical attention if redness or irritation develops.
Remove contaminated clothing and wash before reuse.
Eye Contact:
Rinse eyes with water for at least 15 minutes.
Seek immediate medical attention if irritation persists.
Remove contact lenses if present and continue rinsing.
Ingestion:
If Octenidine dihydrochloride is ingested, rinse mouth with water immediately.
Do not induce vomiting unless directed by medical staff.
Seek immediate medical attention.
Note to Physicians:
Treat symptomatically.
Supportive care recommended.
Monitor gastrointestinal and respiratory functions.
HANDLING AND STORAGE
Handling:
Personal Protection:
Wear gloves, goggles, and protective clothing when handling Octenidine dihydrochloride.
Use respiratory protection if dust may be generated.
Ventilation:
Ensure adequate local exhaust or general ventilation during handling.
Avoidance:
Avoid direct contact with skin, eyes, and clothing.
Do not eat, drink, or smoke when handling.
Wash hands thoroughly after use.
Spill and Leak Procedures:
Collect spills using inert absorbent materials.
Avoid generating dust.
Dispose of in accordance with local regulations.
Storage:
Store Octenidine dihydrochloride in a cool, dry, and well-ventilated area.
Keep containers tightly sealed and protected from light and moisture.
Avoid exposure to high heat and incompatible substances.
Handling Cautions:
Prevent dust formation in handling areas.
Maintain container integrity.
Follow all local and international regulations for handling antiseptic chemicals.
