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OCTYL METHOXYCINNAMATE

OCTYL METHOXYCINNAMATE

IUPAC name: (RS)-2-Ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
CAS Number: 5466-77-3
Chemical formula: C18H26O3
Molar mass: 290.403 g

Octyl methoxycinnamate or ethylhexyl methoxycinnamate (INCI) or octinoxate (USAN), trade names Eusolex 2292 and Uvinul MC80, is an organic compound that is an ingredient in some sunscreens and lip balms.
Octyl methoxycinnamate is an ester formed from methoxycinnamic acid and 2-ethylhexanol.
Octyl methoxycinnamate is a liquid that is insoluble in water.

Octyl methoxycinnamate is primarily used in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage.
Octyl methoxycinnamate is also used to reduce the appearance of scars.

Uses
Octyl methoxycinnamate is the most common active ingredient in sunscreens for protection against UV-B rays.
Octyl methoxycinnamate may be combined with oxybenzone and titanium oxide.

Studies have evaluated the efficacy of octyl methoxycinnamate in preventing postoperative peritoneal adhesions and determined that octyl methoxycinnamate covering peritoneal surfaces decreases adhesion formation.
This effect is more notable when octyl methoxycinnamate is applied before the induction of trauma.

Chromophore groups, such as C=C, C=O, and O-N=O, have loosely held electrons that are excited by radiation.
Hence, octyl methoxycinnamate is able to absorb radiation when the electron energy level is increased to an excited state.

Spectral Information
The UV spectra of octyl methoxycinnamate contains a maximum at 310 nm.

Synthesis
Olefin metathesis has been widely studied.
One of the synthesis pathways for octyl methoxycinnamate includes cross metathesis.
The high efficiency of the nitro-Grela catalyst has been used in the cross metathesis of trans-anethole with 2-ethylhexyl acrylate to produce octyl methoxycinnamate.

Safety studies
One study performed in 2000 raised safety concerns about octyl methoxycinnamate by demonstrating toxicity to mouse cells at concentrations lower than typical levels in sunscreens.
However, another study concluded that octyl methoxycinnamate and other sun screening agents do not penetrate the outer skin in sufficient concentration to cause any significant toxicity to the underlying human keratinocytes.

Estrogenic and neurological effects were noted in laboratory animals at concentrations close to those experienced by sunscreen users and were also shown in vitro.
Octyl methoxycinnamate has been shown to be light sensitive with a decrease in UV absorption efficiency upon light exposure.
This degradation causes formation of the Z-octyl-p-methoxycinnamate from the E-octyl-p-methoxycinnamate.
In contrast, the OMC does not show degradation when kept in darkness for extended periods of time.

A study carried out in 2017 by the Research Centre for Toxic Compounds in the Environment at Masaryk University, Czech Republic, indicates that octyl methoxycinnamate (EHMC) may damage human cell DNA.
When exposed to sun rays, the spatial arrangement of its molecules changes and isomerisation takes place.
While until now only unchanged EHMC has been researched, Massaryk University researchers focused on its isomers and found out that it has a significant genotoxic effect under lab conditions.
Octyl methoxycinnamate means that it may potentially damage human DNA and cause genome mutations which may lead to serious health risks.

In swimming pools with hypochlorite in aqueous solution, octyl methoxycinnamate has been shown to produce chlorine-substituted intermediates.
The chlorination intermediates of octyl methoxycinnamate demonstrated weak mutagenic effects on the Salmonella typhimurium TA 100 strain.
The reactions depended on the pH, compound structures, and chlorine dose.

Density: 1.01 g/cm3
Melting point: −25 °C
Boiling point: 198 °C
XLogP3-AA: 5.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 10
Exact Mass: 290.18819469
Monoisotopic Mass: 290.18819469
Topological Polar Surface Area: 35.5 Ų
Heavy Atom Count: 21
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 1
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

About Octyl methoxycinnamate
Octyl methoxycinnamate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Octyl methoxycinnamate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses of Octyl methoxycinnamate
Octyl methoxycinnamate is used in the following products: cosmetics and personal care products, perfumes and fragrances, air care products, biocides (e.g. disinfectants, pest control products), polishes and waxes, washing & cleaning products, laboratory chemicals, pharmaceuticals and photo-chemicals.
Other release to the environment of Octyl methoxycinnamate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

Article service life of Octyl methoxycinnamate
Other release to the environment of Octyl methoxycinnamate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).
Octyl methoxycinnamate can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and plastic (e.g. food packaging and storage, toys, mobile phones).

Widespread uses by professional workers of Octyl methoxycinnamate
Octyl methoxycinnamate is used in the following products: laboratory chemicals, perfumes and fragrances, pharmaceuticals, photo-chemicals, polishes and waxes, washing & cleaning products and cosmetics and personal care products.
Other release to the environment of Octyl methoxycinnamate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

Formulation or re-packing of Octyl methoxycinnamate
Octyl methoxycinnamate is used in the following products: cosmetics and personal care products, laboratory chemicals, perfumes and fragrances, pharmaceuticals and photo-chemicals.
Release to the environment of Octyl methoxycinnamate can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites of Octyl methoxycinnamate
Octyl methoxycinnamate is used in the following products: cosmetics and personal care products, laboratory chemicals, perfumes and fragrances, pharmaceuticals, photo-chemicals and washing & cleaning products.
Octyl methoxycinnamate is used for the manufacture of: chemicals.
Release to the environment of Octyl methoxycinnamate can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), in the production of articles, as processing aid, for thermoplastic manufacture and as processing aid.

Manufacture of Octyl methoxycinnamate
Release to the environment of Octyl methoxycinnamate can occur from industrial use: manufacturing of the substance.

Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage.
Octyl methoxycinnamate was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun.
Octyl methoxycinnamate is often combined with nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and decrease the risk of percutaneous absorption.
Octyl methoxycinnamate's use in pharmaceutical and cosmetic formulations is approved by FDA.

A clear, oil-soluble, "cosmetically-elegant" liquid that is the most commonly used chemical sunscreen.
Octyl methoxycinnamate absorbs UVB radiation (at wavelengths: 280-320 nm) with a peak protection at 310nm. 

Octyl methoxycinnamate only protects against UVB and not UVA rays (the 320-400 nm range) – so always choose products that contain other sunscreens too.
Octyl methoxycinnamate is not very stable either, when exposed to sunlight, it kind of breaks down and loses its effectiveness (not instantly, but over time - it loses 10% of its SPF protection ability within 35 mins).
To make it more stable it can be - and should be - combined with other sunscreen agents to give stable and broad-spectrum protection (the new generation sunscreen agent, Tinosorb S is a particularly good one for that).

Regarding safety, there are also some concerns around Octinoxate.
In vitro (made in the lab not on real people) and animal studies have shown that it may produce hormonal (estrogen-like) effects.
Do not panic, the studies were not conducted under real life conditions on real human people, so it is probably over-cautious to avoid Octinoxate altogether.
However, if you are pregnant or a small child (under 2 yrs. old), choose a physical (zinc oxide/titanium dioxide) or new-generation Tinosorb based sunscreen, just to be on the super-safe side.

Overall, Ethylhexyl Methoxycinnamate is an old-school chemical sunscreen agent.
There are plenty of better options for sun protection today, but it is considered "safe as used" (and sunscreens are pretty well regulated) and it is available worldwide (can be used up to 10% in the EU and up to 7.5% in the US).

Octyl Methoxycinnamate is a UV-B category 1 sunscreen used for OTC sun protection products such as sunscreens, personal care products, sun care, baby sun care, daily skin care, decorative cosmetic with sun protection and broad spectrum UV- B filter.

Octyl methoxycinnamate, also called Octinoxate or (OMC), is a UV filter. Octyl methoxycinnamate can be absorbed rapidly through skin. Octyl methoxycinnamate has been detected in human urine, blood and breast milk, which indicates that humans are systemically exposed to this compound.
Octyl methoxycinnamate is an endocrine disruptor that mimics estrogen and can disrupt thyroid function.

Found in: Hair color products and shampoos, sunscreen, lipstick, nail polish, skin creams

What to look for on the label: Octinoxate,o methoxycinnamate (OMC), parsol, parsol MCX, parsol MOX, escalol, 2-ethylhexyl p-methoxycinnamate

What is Octyl methoxycinnamate
Octyl methoxycinnamate filters UV‐B rays from the sun.
Octyl methoxycinnamate does not protect against UV-A rays.
Octyl methoxycinnamate dissolves in oil, which makes it a fat-seeking substance in the body.
Octyl methoxycinnamate is formed by combining methoxycinnamic acid and 2-ethylhexanol- compounds which are not harmful on their own.

When mixed together, they form a clear liquid that does not dissolve in water.
Octyl methoxycinnamate is found in hair color products and shampoos, sunscreen, lipstick, nail polish, and skin creams.
In products other than sunscreens, it is used as a UV filter to protect the products from degrading when exposed to the sun.

health concerns: Endocrine disruption, reproductive and developmental toxicity, organ system toxicity

Endocrine disruption: Octinoxate increases cell proliferation in cells that grow in response to estrogen exposure.
Lifetime estrogen exposure is an established risk factor in the development and progression of breast cancer.
Octinoxate affects other hormone systems as well.
For instance, it reduces thyroid hormones in blood serum.

Thyroid hormones are critical for metabolic functions in the body including mammary gland development.
Octyl methoxycinnamate exposure has also been found to alter the reproductive systems of female offspring, with significantly lowered hormone (estradiol and progesterone) levels, which is associated with infertility and miscarriages.
In males there is a reduction of sperm count at all dose levels.

Reproductive organs and development toxicity: Numerous studies have reported that octinoxate exhibits antiandrogenic activity, which is linked to harmful effects on reproductive organ development in male and female fetuses exposed in utero.
These effects can be further passed onto their offspring.
Moreover, octinoxate alters weight and structure of reproductive organs in male and female rats.

Regulations: Octyl methoxycinnamate is approved for use in cosmetics worldwide; the maximum concentration in ready-for-use preparations varies according to local legislation.
According to the U.S. FDA the recommended use levels is up to 7.5 percent.

how to avoid: Despite the numerous studies and concerns about octinoxate toxicity and the effect on human body systems, octinoxate is approved worldwide [3]. In the United States, it is required to be listed on labels as an active ingredient. To avoid the product in sunscreen, read the list of active ingredients and skip products that rely on octinoxate. Check labels on hair care products, lipsticks nail polish and skin creams, and choose products that do not contain octinoxate or octyl methoxycinnamate (OMC).

Octyl Methoxycinnamate is an organic ester used in sunscreens (and lip balms) formed from methoxycinnamic acid and 2-ethylhexanol (Source).
Octyl methoxycinnamate is a sun blocking agent that absorbs UVB rays, but not UVA rays.
However, when it is exposed to sunlight, it is rendered less effective, although this reaction can be prevented by the addition of other ingredients (as seen in the formula of Tinsorb).
Octyl methoxycinnamate is also used to reduce to appearance of scars.

Safety Measures: 
According to the Cosmetics Database, which rates Octyl Methoxycinnamate as 70% safe, there are many concerns regarding its use, including: biochemical changes that cause mutation and cell death upon exposure to sunlight (which is likely when used as a sunscreen ingredient); immunotoxicity and photoallergic effects; reproductive toxicity that leads to estrogenic effects; organ system toxicity, especially in the liver; and enhanced skin absorption. Octyl methoxycinnamate should be used with caution by pregnant women and children.

One study performed in 2000 raised safety concerns about Octyl Methoxycinnamate's toxicity, but was performed on mouse cells at concentrations lower than typical levels in sunscreens.
"However, a more recent study concluded that Octyl Methoxycinnamate does not penetrate the outer skin in sufficient concentration to cause any significant toxicity to the underlying human keratinocytes.
Estrogenic effects were noted in laboratory animals at concentrations close to those experienced by sunscreen users".

Octyl Methoxycinnamate at a Glance
Globally approved UV filter in use for over 50 years
Provides excellent UVB protection and filters a portion of UVA rays
Backed by numerous studies confirming its safety as used in sunscreens
Octyl methoxycinnamates cinnamic acid component can be allergenic for some
Also known as octyl methoxycinnamate and ethylhexyl methoxycinnamate

Octyl Methoxycinnamate is sunscreen agent used to protect skin primarily from the sun’s UVB rays.
Octyl Methoxycinnamate is one of several currently undergoing further safety testing under the purview of the United States Food and Drug Administration (FDA).
This testing is to gain a better understanding of the systemic absorption, metabolism, and elimination of these sunscreen actives when small amounts enter the body via topical use.

Octyl methoxycinnamate’s important to know that the presence of this or other sunscreen actives in the body does not mean your health is at risk.
Octyl methoxycinnamate is anticipated that the additional testing being done will reaffirm the safety of these ingredients; however, those who remain concerned can choose sunscreens with mineral actives (titanium dioxide and zinc oxide) which are not included in the FDA’s new call for additional testing.

Octyl Methoxycinnamate has a solid record of safety backed by decades of research and mounds of studies.
No studies have demonstrated that octinoxate, as used in SPF products, is harmful to people.
In the studies where such claims are made, the conditions are simply do not apply to how Octyl Methoxycinnamate is used in sunscreens.

This sunscreen ingredient’s cinnamic acid component can be allergenic for some people; however, this is an individual response and simply means your skin cannot tolerate this ingredient.
Octyl Methoxycinnamate is not considered irritating or photosensitizing to broad populations.

The risk of an allergic response can be minimized by formulating Octyl Methoxycinnamate in the oil phase (not the water phase) of a sunscreen.
This along with other formulary steps such as encapsulation and special emulsification approaches also stabilize Octyl Methoxycinnamate.
When such steps are not taken, upwards of 60% of Octyl Methoxycinnamate’s protective ability in a sunscreen is lost when exposed to UV light.
But since this issue is well known among sunscreen chemists, it’s not a concern for today’s sunscreens with oOctyl Methoxycinnamate.

Octyl Methoxycinnamate is sometimes accused of being a hormone disruptor.
This effect has primarily been demonstrated via oral intake of large amounts of this ingredient or examining its effect on isolated cells.
In cases where a hormonal change was measured via topical application, the difference was one million-fold less than what was measured from normal hormonal activity in the body.
Studies involving people have shown that Octyl Methoxycinnamate does not have a biologically significant effect on hormones.

There simply isn’t any research backing the claim that Octyl Methoxycinnamate has any link to health risks when used in sunscreen formulas.
In fact, the European Union’s (EU) permitted usage level for Octyl Methoxycinnamate in sunscreens is higher than the maximum amount permitted in the United States (7.5% in the United States, 10% in the EU).
China, Australia, Brazil, Argentina, India and Thailand are among the other countries permitting Octyl Methoxycinnamate levels up to 10%.

Octyl Methoxycinnamate is often accused of being a threat to coral reefs and has been banned from use in sunscreen in some parts of the world; however, numerous data gaps exist on this issue.
Such gaps include the lack of information on many other UV filters whose effects on coral reefs have yet to be studied.
More important, research is clear that several other factors, from changing climate to coastal development and invasive species have a much stronger link to coral reef damage and demise than sunscreen use by people.

This sunscreen active is one of several currently undergoing further safety testing under the purview of the United States Food and Drug Administration (FDA).
This testing is to gain a better understanding of the systemic absorption, metabolism, and elimination of these sunscreen actives when small amounts enter the body via topical use.

As referenced above, the presence of this or other sunscreen actives in the body does not mean your health is at risk.
Octyl methoxycinnamate is anticipated that the additional testing being done will reaffirm the safety of these ingredients; however, those who remain concerned can choose sunscreens with mineral actives (titanium dioxide and zinc oxide) which are not included in the FDA’s new call for additional testing.

Octyl Methoxycinnamate or ethylhexyl methoxycinnamate, trade names Eusolex 2292 and Uvinul MC80, is an organic compound that is an ingredient in some sunscreens and lip balms.
Octyl methoxycinnamate is an ester formed from methoxycinnamic acid and 2-ethylhexanol.
Octyl methoxycinnamate is a liquid that is insoluble in water.
Octyl methoxycinnamate is primarily used in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage.
Octyl methoxycinnamate is also used to reduce the appearance of scars.

Octyl Methoxycinnamate is an organic compound that is an ingredient in some sunscreens and lip balms. Octyl methoxycinnamate is an ester formed from methoxycinnamic acid and (RS)-2-ethylhexanol.
Octyl Methoxycinnamate is a clear liquid that is insoluble in water.
Octyl methoxycinnamate's primary use is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage.
Octyl methoxycinnamate is also used to reduce the appearance of scars.

Ethylhexyl Methoxycinnamate is one of the most used sun filters in the world.
Ethylhexyl Methoxycinnamate is organic, oil-soluble and absorbs UV-B radiation at wavelengths from 280 to 320nm, with a peak protection at 310nm.
Ethylhexyl Methoxycinnamate is being used in a wide range of cosmetic products to provide an appropriate Sun Protection Factor (SPF) in sunscreens or to protect cosmetics against UV radiation.
In cosmetic products it also acts as a photo stabilizer and it helps to protect colors and fragrances.

An organic compound that is an ingredient in some sunscreens and lip balms as a UV absorber/filter. Octyl methoxycinnamate is an ester formed frommethoxycinnamic acid and (RS)-2-ethylhexanol.
Octyl methoxycinnamate is a clear liquid that is insoluble in water.
Octyl methoxycinnamate's primary use is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage. Octyl methoxycinnamate is also used to reduce the appearance of scars.

Octyl methocycinnamate can be found in hair color products and shampoos, sunscreen, lipstick, nail polish, skin creams.
A recent study concluded that octyl methoxycinnamate and other sun screening agents do not penetrate the outer skin in sufficient concentration to cause any significant toxicity to the underlying human keratinocytes.

Estrogenic effects were noted in laboratory animals at concentrations close to those experienced by sunscreen users and were also shown in test tube experiments.
A study published in 2011 explored the effects of pre- and post-natal exposure to high doses of octyl methoxycinnamate in rats and showed, for example, that the testes weight and testosterone levels were significantly reduced in male rats.

This common sunscreen ingredient is shown to have hormone-mimicking effects on laboratory animals. This chemical is found in humans, including mothers' milk samples.
Octyl methoxycinnamate is one of the most frequently used chemical UV filters worldwide and has been reported to cause photosensitisation and photoallergic effects.
Octyl methoxycinnamate easily penetrates the upper layer of the skin and, when exposed to UV radiation, generates free radicals in skin cells.

Ethylhexyl Methoxycinnamate is a clear liquid that is insoluble in water.
Ethylhexyl Methoxycinnamate is used in the formulation of many types of beauty products, including sunscreens and makeup products that marketed to contain ingredients that protect the skin from the sun.
Octyl methoxycinnamate is often listed as Octinoxate on sunscreen products.
When you see on the ingredient listed for shampoos and other hair care products is it being used to protect these personal care products from deterioration caused by UV rays.

UV light has a wavelength shorter than visible light.
Prolonged exposure to UV light may result in health effects in the skin, eye and immune system.
UV light damages collagen and contributes to aging of skin.
Ethylhexyl Methoxycinnamate (Octinoxate) can help protect against sunburn and other skin damage caused by UV light by absorbing UV radiation.

The Food and Drug Administration (FDA) conducted an OTC (over the counter) drug review of Ethylhexyl Methoxycinnamate and did approve it for use in sunscreens up to a concentration of 7.5%.
There are some studies that this ingredient may produce excess reactive oxygen species that can interfere with cellular signaling, cause mutations, and lead to cell death.

This reaction may also be implicated in cardiovascular disease.
However, another study concluded that octyl methoxycinnamate and other sun screening agents do not penetrate the outer skin in sufficient concentration to cause any significant toxicity.
Once again, we as consumers need to balance the benefits of the ingredients against the harmful side effects.

Octyl methoxycinnamate is a chemical sun blocking agent that absorbs ultraviolet radiation in UVB range.
Octyl methoxycinnamate is a chemical ingredient found in some brands of sunscreen and lip balm that blocks UV-B rays from the sun to protect the skin against harmful radiation.
Octyl methoxycinnamate is the most commonly used chemical for blocking UV-B rays.
Octyl methoxycinnamate is an organic compound formed from methoxycinnamic acid and 2-ethylhexanol. When mixed together, they form a clear liquid that does not dissolve in water.

Octyl methoxycinnamate can absorb UV-B rays from the sun but does not protect against UV-A rays.
Octyl methoxycinnamate is the nomenclature termed by the International Nomenclature of Cosmetic Ingredients (INCI), which provides names for certain chemicals and other ingredients used in soaps, cosmetics and related ingredients.
Octyl methoxycinnamate is referred to as octinoxate according to the United States Adopted Names (USAN), which provides individual names for pharmaceutical products sold in the United States.

Growing demand for skin care is expected to drive the skin care products market within the forecast period as there is an increasing awareness regarding healthy skin among consumers.
This in turn is expected to drive the demand for octyl methoxycinnamate in the market.
Skincare is the largest segment present within the personal care industry.
Skincare products include face creams, hand and body lotions, sun care products and facial treatment products.

Changing lifestyle and increase in disposable income of consumers, particularly in emerging economies such as China, India and Brazil, is expected to drive the personal care industry, thereby augmenting the demand for octyl methoxycinnamate.
The consumption of octyl methoxycinnamate based skin products has become high on account of factors such as hectic lifestyle and pollution damage human health and skin.
Men’s grooming has become a mainstream market in the past few decades and this industry is anticipated to grow further driving the octyl methoxycinnamate market.

Furthermore, rising awareness regarding sunscreen lotions and creams is expected to fuel the demand further for octyl methoxycinnamate over the next few years.
However, octyl methoxycinnamate safety concerns have been raised regarding possible estrogenic and other adverse effects of octyl methoxycinnamate, especially in children and pregnant women.
Additionally, octyl methoxycinnamate is absorbed into the skin and has been shown in some studies to promote generation of potentially harmful free radicals.
This may act as a major restraining factor to the octyl methoxycinnamate market.

Regions such as Asia Pacific, Africa and Latin America are predicted to emerge as the fastest growing markets for octyl methoxycinnamate. The continual and rapid growth in the industries such as skin care and cosmetics care in these regions is expected to drive the demand for octyl methoxycinnamate in the production of various applications products.
Moreover, developed markets such as the U.S. and European economies are steadily recovering from the economic downturn and are anticipated to generate significant demand for octyl methoxycinnamate in the coming years.

Octyl methoxycinnamate or abbreviated OMC or OM-Cinnamate or Octinoxate is a sunscreen agent.
Organic sunscreen   Obtained from Cinnamic Acid (an acid found in the plant Cinnamon) is effective against UVB light.

Appearance
Clear colorless to pale yellow liquid.

Function
Octyl methoxycinnamates primary use is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage.
Octyl methoxycinnamate is also used to reduce the appearance of scars.

Octyl Methoxycinnamate is an UV Absorber and it is used in products that are applied to the skin and hair (such as Hair & Body Sun spray) to absorb, reflect or scatter UV rays.
This serves to protect the skin from sunburn as well as other damaging effects of the sun to skin and hair.
Octyl Methoxycinnamate also protects cosmetics and personal care products from deterioration caused by UV rays.

Snyonyms:
Ethylhexyl methoxycinnamate
Octinoxate
Uvinul MC80
(E)-3-(4-methoxyphenyl) prop-2-enoic acid 2-ethylhexyl ester
226-775-7
2-Ethylhexyl (2E)-3-(4-methoxyphenyl)-2-propenoate
2-Ethylhexyl (2E)-3-(4-methoxyphenyl)acrylate
2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
2-Ethylhexyl p-methoxycinnamate
2-Ethylhexyl trans-4-methoxycinnamate
2-Propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester, (2E)-
3612129
4Y2&1OV1U1R DO1 &&E
4Y5P7MUD51
PARSOL MCX
Sunscreen AV
UNII:4Y5P7MUD51
Uvinul 3088
Uvinul MC 80
(S)-2-(methoxymethyl)piperidine
[5466-77-3]
2-Ethylhex-1-yl 3-(4-methoxyphenyl)acrylate
2-Ethylhex-1-yl 3-(4-methoxyphenyl)prop-2-enoate
2-ethylhexyl (E)-3-(4-methoxyphenyl)prop-2-enoate
2-Ethylhexyl 3-(4-methoxyphenyl)-2-propenoate
2-Ethylhexyl 4-methoxycinnamate
4-methoxycinnamic acid 2-ethylhexyl ester
C118580
cinnamic acid, 4-methoxy-, 2-ethylhexyl ester
DB09496
Escalol
MFCD00072582
Heliopan
OMC
OMC cinnamate
PARSOL
Parsol MOX
UD3392732
UvinulT MC 80 N
Octinoxate
5466-77-3
83834-59-7
2-Ethylhexyl 4-methoxycinnamate
2-Ethylhexyl-p-methoxycinnamate
Parsol MCX
2-Ethylhexyl trans-4-methoxycinnamate
4-Methoxycinnamic Acid 2-Ethylhexyl Ester
Octyl methoxycinnamate
Parsol
2-Ethylhexyl 3-(4-methoxyphenyl)acrylate
2-Ethylhexyl p-methoxycinnamate
Escalol 557
octyl-methoxycinnamate
(E)-2-Ethylhexyl 3-(4-methoxyphenyl)acrylate
Parsol MOX
2-Ethylhexyl-4-methoxycinnamate
2-ethylhexyl (E)-3-(4-methoxyphenyl)prop-2-enoate
Ethylhexyl methoxycinnamate
Octyl 4-methoxycinnamic acid
CHEBI:88667
NSC 26466
2-Propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester, (2E)-
2-Ethylhexyl methoxycinnamate
Neo heliopan AV
Heliopan New
Uvinul MC 80
Octyl p-Methoxycinnamate
NSC-26466
NCGC00160623-01
Parsol (TN)
UvinulT MC 80 N
2-ethylhexyl 3-(4-methoxyphenyl)-2-propenoate
EC 629-661-9
DSSTox_CID_28119
DSSTox_RID_82199
DSSTox_GSID_47205
SCHEMBL15609
MLS004773966
CHEMBL1200608
DTXSID9047205
3-(4-Methoxyphenyl)-2-propenoic acid 2-ethylhexyl ester
4-Methoxycinnamic Acid Octyl Ester
HY-B1234
NSC26466
p-Methoxyzimtsaure-2-ethylhexylester
Tox21_302576
MFCD00072582
s5320
AKOS015838519
2-Ethylhexyl 4-methoxycinnamate
CCG-267384
CS-4732
DB09496
NCGC00160623-02
NCGC00160623-03
NCGC00181309-01
NCGC00256897-01
AS-11708
SMR001550370
CAS-83834-59-7
4-METHOXYCINNAMICACID2-ETHYLHEXYLESTER
M1082
Z3587
(E)-2-Ethylhexyl3-(4-methoxyphenyl)acrylate
D05225
D95744
A840663
Q739648
SR-01000883955
2-Ethylhexyl 4-methoxycinnamate, analytical standard
SR-01000883955-1
3-(4-Methoxy-phenyl)-acrylic acid 2-ethyl-hexyl ester
C118580000

 

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