PRODUCTS

OCTYLDODECANOL

CAS No. : 5333-42-6
EC No. : 226-242-9

Synonyms:
2-Octyldodecan-1-ol; 2-Octyldodecan-1-ol; 2-Octyldodecanol; Eutanol G; Guerbet C20; Isofol 20; Kalcohl 200G; 2-Octyldodecan-1-ol; 2-Octyl-1-dodecanol; 5333-42-6; Octyldodecanol; 2-Octyldodecanol; 1-DODECANOL, 2-OCTYL-; 2-Octyl dodecanol; Standamul G; Eutanol G; Isofol 20; 2-Octyldodecyl alcohol; Kalcohl 200G; Rilanit G 20; Exxal 20; Octyl dodecanol; Kalcohl 200GD; 2-n-octyl-1-dodecanol; 2-Octyldecanol; 2-octildodecanol; Guerbet C20; Risonol 20SP; CAS-5333-42-6; Octyldodecanol [NF]; Jarcol I 20; Fine Oxocol 2000; C20H42O; OHV 180; 2-octyl-dodecanol; ACMC-1AWZN; Michel XO-150-20; EC 226-242-9; SCHEMBL4873; 3-01-00-01844 (Beilstein Handbook Reference); 2-Octyl-1-dodecanol, 97%; 2-octyldodecan-1-ol, octyldodecanol; 2-octyldodecan-1-ol 5333-42-6; OCTYLDODECANOL; Octyldodecanol; 2-Octyldodecan-1-ol; 2-Octyl-1-dodecanol; 5333-42-6; Octyldodecanol; 2-Octyldodecanol; 1-DODECANOL, 2-OCTYL-; Standamul G; 2-Octyl dodecanol; Eutanol G; Isofol 20; 2-Octyldodecyl alcohol; Kalcohl 200G; Rilanit G 20; Exxal 20; Octyl dodecanol; Kalcohl 200GD; 2-n-octyl-1-dodecanol; 2-Octyldecanol; 2-octildodecanol; Guerbet C20; Risonol 20SP; CAS-5333-42-6; Octyldodecanol [NF] ; Jarcol I 20; Fine Oxocol 2000; C20H42O; OHV 180; 2-octyl-dodecanol; ACMC-1AWZN; Michel XO-150-20; 2-octyldodecan-1-ol, octyldodecanol; Tox21_112351; Tox21_302294; 2-octyldodecan-1-ol ; 5333-42-6; Octyldodecanol; Octyl dodecanol; Oktildodekanol; Oktil dodekanol; Octildodecanol; Octil dodecanol; Octildodekanol; Octil dodekanol; Octyldodekanol; Octyl dodekanol; Oktyildodekanol; Oktyil dodekanol; 2-Octyldodecan-1-ol; 2-Octyldodecan-1-ol; 2-Octyldodecanol; Eutanol G; Guerbet C20; Isofol 20; Kalcohl 200G; 2-Octyldodecan-1-ol; 2-Octyl-1-dodecanol; Octyldodecanol, European Pharmacopoeia (EP) Reference Standard; Octyldodecanol, United States Pharmacopeia (USP) Reference Standard; Octyldodecanol, Pharmaceutical Secondary Standard; Certified Reference Material; octyldodecanol water

Octyldodecanol

Octyldodecanol is a clear, odorless fatty alcohol produced from natural fats and oils. It is stable to hydrolysis and can be used over a wide pH range. It provides the skin with a soft and smooth appearance. It is an ideal solvent to dissolve salicylic acid. It is used in all kinds of skin care, sun care, perfumes and color cosmetics products.

OCTYLDODECANOL is classified as :
Emollient
Solvent
Perfuming

CAS Number 5333-42-6
EINECS/ELINCS No: 226-242-9
COSING REF No: 35610
Chem/IUPAC Name: 2-Octyldodecan-1-ol

Octyldodecanol is a branched-chain primary alcohol used as the isomer 2-octyl-1-dodecanol in cosmetics such as lipstick[1] as an anti-blooming agent, facepowder,[2] It is a medium spreading emollient, with equilibrium spreading pressure of 17.0 dyne/cm.[3] Octyldodecanol is in the class of Guerbet alcohols, because it has the branch at the β position.[4] Compared to arachidyl alcohol, the linear alcohol of the same molecular weight, it has a lower melting point, yet retains low volatility.[4]

Production
2-Octyldodecanol is produced by the Guerbet condensation of decyl alcohol.[5]

Reactions
When octyldodecanol is melted with an alkali it yields octyldodecanoic acid by a dehydrogenation reaction.

Properties
Chemical formula C20H42O
Molar mass 298.555 g·mol−1
Appearance yellow oil
Density 0.84
Melting point 1 °C (34 °F; 274 K)
Boiling point 382 °C (720 °F; 655 K)
Refractive index (nD) 1.454

What Is It?
Stearyl Alcohol, Oleyl Alcohol and Octyldodecanol are long chain fatty alcohols. Stearyl Alcohol is a white, waxy solid with a faint odor, while Oleyl Alcohol and Octyldodecanol are clear, colorless liquids. These three ingredients are found in a wide variety of products such as hair conditioners, foundations, eye makeup, skin moisturizers, skin cleansers and other skin care products.

Why is it used in cosmetics and personal care products?
Stearyl Alcohol, Oleyl Alcohol and Octyldodecanol help to form emulsions and prevent an emulsion from separating into its oil and liquid components. These ingredients also reduce the tendency of finished products to generate foam when shaken. When used in the formulation of skin care products, Stearyl Alcohol, Oleyl Alcohol and Octyldodecanol act as a lubricants on the skin surface, which gives the skin a soft, smooth appearance.

Scientific Facts:
Stearyl Alcohol and Oleyl Alcohol are mixtures of long-chain fatty alcohols. Stearyl Alcohol consists primarily of n-octadecanol, while Oleyl Alcohol is primarily unsaturated 9-n-octadecenol. Octyldodecanol is a branched chain fatty alcohol. Fatty alcohols are higher molecular weight nonvolatile alcohols. They are produced from natural fats and oils by reduction of the fatty acid (-COOH) grouping to the hydroxyl function (-OH). Alternately, several completely synthetic routes yield fatty alcohols which may be structurally identical or similar to the naturally-derived alcohols.

Categories: Texture Enhancer, Emollients

Clear colorless liquid that’s considered a long-chain fatty acid. It’s often used as a texture enhancer in moisturizers and lip products due to its lubricating and emollient properties. Octyldodecanol also helps prevent a formula from separating into its oil and liquid components. It’s a synthetic ingredient.

USAGE AREAS
Oil-Free Emollient,
Solvent & Moisturizer

CAS: 5333-42-6
INCI Name: Octyldodecanol

Benefits:
Emollient, solvent, and moisturizer for all kinds of skin care products
Provides the skin a soft, smooth appearance
Ideal solvent to dissolve salicylic acid
Use: Add to formulas as is, add to oil phase, typical use level 2-20%. For external use only.
Applications: All kinds of skin care, sun care products, various color cosmetics.
Country of Origin: USA
Raw material source: Vegetable oils
Manufacture: Octyldodecanol is a branched fatty alcohol produced from natural fats and oils by reduction of the fatty acid grouping to the hydroxyl function.
Animal Testing: Not animal tested
GMO: No data available
Vegan: Does not contain animal-derived components

Octyldodecanol is a long chain fatty alcohol. It is a medium spreading emollient which is due to its chemical structure hydrolysis stable and therefore beneficially suitable for all formulations where a wide pH range is needed e.g. deo/antiperspirant and hair remover formulations. It is an emulsifier and opacifying agent, used primarily as a thickener in moisturizers because of its lubricating and emollient properties in the formulation of skin care products. Octyldodecanol is approved by ECOCERT for Natural and Organic Cosmetics.

Effects of ethylcellulose and 2-octyldodecanol additives on skin permeation and irritation with ethylene-vinyl acetate copolymer matrix patches containing formoterol fumarate.

What Is Octyldodecanol?
Octyldodecanol is a long chain fatty acid. It looks like a clear, colourless liquid. It can be synthetic or derived from plants.

What Does Octyldodecanol Do In Skincare Products?
Octyldodecanol has several jobs in skincare products:

Anti-foaming: It helps reduce the tendency of products to foam when they’re shaken.
Emollient: It makes skin silky soft to the touch.
Emulsifier: It helps keep formulas together, preventing the oily and watery parts from separating.
Texture-enhancer: It gives the textures of skincare products a better slip, so they can glide smoothly on the skin.
Solvent: It’s rarely used for this, but it can dissolve other skincare ingredients.
Octyldodecanol is there more for the product than for your skin. It can make skin softer and smoother, but it mostly helps to create skincare products that are a pleasure to use.

Does Octyldodecanol Has Any Side Effects?
Octyldodecanol can cause irritations even in low doses, but it’s rare. Unless you have sensitive skin, I wouldn’t worry too much about it.

The Bottom Line
Octyldodecanol is an emollient and emulsifier that improves the texture of your skincare products and makes your skin softer and smoother.

Octyldodecanol is a long-chain fatty alcohol used in a wide variety of beauty products as an emollient and emulsifier, but also rarely as a solvent and fragrance ingredient as well. It is a clear, colorless liquid that is often seen as a thickener in moisturizers because of its lubricating and emollient properties (Source).

* An emollient and emulsifier

Functions:

According to CosmeticsInfo.org, Octyldodecanol helps to form emulsions and prevents formulas from separating into its oil and liquid components. It can also reduce the tendency of finished products to generate foam when shaken. Octyldodecanol acts as a lubricant on the skin, giving a soft, silky feel as an ingredient in lotion.

Safety Measures/Side Effects:

The EWG rates Octyldodecanol as low hazard, although it should be noted that a study published in Cosmetics and Toiletries in 1979 showed irritation occurred in tests of Octyldodecanol, even in low concentrations, and again in a study published in the Journal of Toxicology in 1985. However, both were results were found when tested on rabbits. A 2006 study found that it enhanced the irritation of other ingredients.

Clear, odorless oil with excellent solvent properties. Can be used in almost any cosmetic product, from lip balm to skin lotions, facial cleansers and color cosmetics. Stable to hydrolysis and can be used over a wide pH range. Medium spreading qualities. Moisturizes skin & hair, stabilizes lotions & creams. Solvent for perfume ingredients, also salicylic acid. Clear liquid, odorless. Synonym: 2-octyl dodecanol.

Octyldodecanol is a fatty alcohol used for its solvent and emollient properties in cosmetics. It is produced from natural fats and oils. It can be easily used in a wide range of cosmetics, it moisturizes the skin and hair, stabilizes lotions and creams. It is used as a solvent in perfumes. It is authorized in organic.
Its functions (INCI)
Emollient : Softens and softens the skin
Masking : Reduces or inhibits the odor or basic taste of the product
Perfuming : Used for perfume and aromatic raw materials
Solvent : Dissolves other substances

What Is Octyldodecanol?
Stearyl Alcohol, Oleyl Alcohol and Octyldodecanol are long chain fatty alcohols. Stearyl Alcohol is a white, waxy solid with a faint odor, while Oleyl Alcohol and Octyldodecanol are clear, colorless liquids. These three ingredients are found in a wide variety of products such as hair conditioners, foundations, eye makeup, skin moisturizers, skin cleansers and other skin care products.

Why is Octyldodecanol used in cosmetics and personal care products?
Stearyl Alcohol, Oleyl Alcohol and Octyldodecanol help to form emulsions and prevent an emulsion from separating into its oil and liquid components. These ingredients also reduce the tendency of finished products to generate foam when shaken. When used in the formulation of skin care products, Stearyl Alcohol, Oleyl Alcohol and Octyldodecanol act as a lubricants on the skin surface, which gives the skin a soft, smooth appearance.

Octyldodecanol
Octyldodecanol.svg
Names
IUPAC name
2-Octyl-1-dodecanol
Other names
2-Octyldodecan-1-ol, 2-Octyldodecanol, Eutanol G, Guerbet C20, Isofol 20, Kalcohl 200G
Identifiers
CAS Number
5333-42-6
3D model (JSmol)
Interactive image
ChEMBL
ChEMBL1572050
ChemSpider
20125
DrugBank
DB14134
ECHA InfoCard   100.023.857 Edit this at Wikidata
EC Number
226-242-9
KEGG
C20338
PubChem CID
21414
Properties
Chemical formula   C20H42O
Molar mass   298.555 g·mol−1
Appearance   yellow oil
Density   0.84
Melting point   1 °C (34 °F; 274 K)
Boiling point   382 °C (720 °F; 655 K)
Refractive index (nD)   1.454
Hazards
Flash point   113 °C (235 °F; 386 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Octyldodecanol is a branched-chain primary alcohol used as the isomer 2-octyl-1-dodecanol in cosmetics such as lipstick[1] as an anti-blooming agent, facepowder,[2] It is a medium spreading emollient, with equilibrium spreading pressure of 17.0 dyne/cm.[3] Octyldodecanol is in the class of Guerbet alcohols, because it has the branch at the β position.[4] Compared to arachidyl alcohol, the linear alcohol of the same molecular weight, it has a lower melting point, yet retains low volatility.[4]

Production
2-Octyldodecanol is produced by the Guerbet condensation of decyl alcohol.[5]

Reactions
When octyldodecanol is melted with an alkali it yields octyldodecanoic acid by a dehydrogenation reaction.

OCTYLDODECANOL
Octyldodecanol is a clear, odorless fatty alcohol produced from natural fats and oils. It is stable to hydrolysis and can be used over a wide pH range. It provides the skin with a soft and smooth appearance. It is an ideal solvent to dissolve salicylic acid. It is used in all kinds of skin care, sun care, perfumes and color cosmetics products.
OCTYLDODECANOL is classified as :
Emollient
Solvent
Perfuming
CAS Number   5333-42-6
EINECS/ELINCS No:   226-242-9
COSING REF No:   35610
Chem/IUPAC Name:   2-Octyldodecan-1-ol

octyldodecanol
Rating: GOOD
Categories: Texture Enhancer, Emollients
Clear colorless liquid that’s considered a long-chain fatty acid. It’s often used as a texture enhancer in moisturizers and lip products due to its lubricating and emollient properties. Octyldodecanol also helps prevent a formula from separating into its oil and liquid components. It’s a synthetic ingredient.

Details
A clear, slightly yellow, odorless oil that's a very common, medium-spreading emollient. It makes the skin feel nice and smooth and works in a wide range of formulas.

Functions:

Octyldodecanol helps to form emulsions and prevents formulas from separating into its oil and liquid components. It can also reduce the tendency of finished products to generate foam when shaken. Octyldodecanol acts as a lubricant on the skin, giving a soft, silky feel as an ingredient in lotion.

Safety Measures/Side Effects:

Description: Octyldodecanol (Synonym: 2-octyl dodecanol) is a clear, odorless fatty alcohol with excellent solvent properties. It is produced from natural fats (non animal) and oils by reduction of the fatty acid grouping to the hydroxyl function. It can be used in almost any cosmetic product, from lip balm to skin lotions, facial cleansers and color cosmetics, silicone alternative. Stable to hydrolysis and can be used over a wide pH range. Medium spreading qualities. Moisturizes skin & hair, stabilizes lotions & creams. Solvent for perfume ingredients, also salicylic acid. Clear liquid, odorless. Water-insoluble, miscible in alcohol, soluble in paraffin oil.
CAS: 5333-42-6
INCI Name: Octyldodecanol
Benefits:
Emollient, solvent, and moisturizer for all kinds of skin care products
Provides the skin a soft, smooth appearance
Ideal solvent to dissolve salicylic acid
Use: Add to formulas as is, add to oil phase, typical use level 2-20%. For external use only.
Applications: All kinds of skin care, sun care products, various color cosmetics.
Country of Origin: USA
Raw material source: Vegetable oils
Manufacture: Octyldodecanol is a branched fatty alcohol produced from natural fats and oils by reduction of the fatty acid grouping to the hydroxyl function.
Animal Testing: Not animal tested
GMO: No data available
Vegan: Does not contain animal-derived components

About Octyldodecanol
Helpful information
Octyldodecanol is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

Octyldodecanol is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses
Octyldodecanol is used in the following products: lubricants and greases, coating products, fillers, putties, plasters, modelling clay, washing & cleaning products, finger paints, air care products, polishes and waxes and cosmetics and personal care products.
Other release to the environment of Octyldodecanol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Article service life
Release to the environment of Octyldodecanol can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release, formulation of mixtures and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).

Other release to the environment of Octyldodecanol is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
Octyldodecanol can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines), vehicles and vehicles not covered by End of Life Vehicles (ELV) directive (e.g. boats, trains, metro or planes).

Octyldodecanol can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), rubber (e.g. tyres, shoes, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).

Widespread uses by professional workers
Octyldodecanol is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners, hydraulic fluids and metal working fluids.

Octyldodecanol is used in the following areas: formulation of mixtures and/or re-packaging.
Octyldodecanol is used for the manufacture of: rubber products, plastic products and chemicals.

Other release to the environment of Octyldodecanol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Formulation or re-packing
Octyldodecanol is used in the following products: washing & cleaning products, coating products and inks and toners.
Release to the environment of Octyldodecanol can occur from industrial use: formulation of mixtures.

USES at industrial sites
Octyldodecanol is used in the following products: washing & cleaning products, lubricants and greases, polymers, coating products, inks and toners and fillers, putties, plasters, modelling clay.
Octyldodecanol is used in the following areas: formulation of mixtures and/or re-packaging.
Octyldodecanol is used for the manufacture of: chemicals, rubber products and plastic products.
Release to the environment of Octyldodecanol can occur from industrial use: in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.

Manufacture
Release to the environment of Octyldodecanol can occur from industrial use: manufacturing of the substance, formulation of mixtures and formulation in materials.

Octyldodecanol occurs as a clear, colorless, or yellowish, oily liquid.

Octyldodecanol is widely used in cosmetics and pharmaceutical applications as an emulsifying and opacifying agent. It is primarily used in topical applications because of its lubricating and emollient properties.
Octyldodecanol has been used in the preparation of oil/water microemulsions investigated as the vehicle for the dermal administration of drugs having no or low skin penetration.Octyldodecanol has also been evaluated as a solvent for naproxen when applied topically.Studies of estimated permeability coefficient suggest that octyldodecanol could be a potential dermal permeation enhancer.

Safety
Octyldodecanol is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as nontoxic and nonirritant at the levels employed as an excipient.
In acute oral toxicity studies in rats fed 5 g/kg of undiluted octyldodecanol, no deaths were observed.In an acute dermal toxicity study, intact and abraded skin sites of guinea pigs were treated with 3 g/kg of undiluted octyldodecanol under occlusive patches; no deaths occurred and no gross skin lesions were observed.Octyldodecanol caused either no ocular irritation or minimal, transient irritation in the eyes of rabbits.However, some sources describe undiluted octyldodecanol as an eye and severe skin irritant.

The bulk material should be stored in a well-closed container in a cool, dry place, protected from light. In the original unopened container, octyldodecanol can be stored for 2 years protected from moisture at below 30°C.

2-Octyl-1-dodecanol is generally compatible with most materials encountered in cosmetic and pharmaceutical formulations.