OLIGOPEPTIDE-24

Oligopeptide-24 is a synthetic cosmetic peptide widely used in advanced anti-aging and skin-conditioning formulations.
Oligopeptide-24 helps support smoother, firmer, and more revitalized-looking skin while complementing products designed for elasticity and wrinkle care.
Oligopeptide-24's peptide-based profile makes it especially suitable for serums, creams, eye-care products, and intensive rejuvenating treatments.

CAS Number: 1018685-16-9
Molecular Formula: C50H78N16O19S2
Molecular Weight: approx. 1271.38 g/mol

Synonyms: H-Cys-Met-Tyr-Ile-Glu-Gly-Gly-Gly-Gly-Arg-Gly-Asp-Gly-OH, H-CMYIEGGGGRGDG-OH, L-Cysteinyl-L-methionyl-L-tyrosyl-L-isoleucyl-L-α-glutamylglycylglycylglycylglycyl-L-arginylglycyl-L-α-aspartylglycine, L-cysteinyl-L-methionyl-L-tyrosyl-L-isoleucyl-L-alpha-glutamyl-glycyl-glycyl-glycyl-glycyl-L-arginyl-glycyl-L-alpha-aspartyl-glycine, CG-EDP3

Oligopeptide-24 regulates cell growth and promotes growth.
Oligopeptide-24 stimulates the metabolism of skin cells, promoting collagen and elastin generation.

Oligopeptide-24 can reduce skin redness, swelling, and sensitivity by inhibiting inflammatory reactions.
Oligopeptide-24 is suitable for use in anti-wrinkle and anti-aging cosmetics.

Oligopeptide-24 is a potent synthetic peptide used in skincare for its ability to stimulate the production of elastin and hyaluronic acid, thereby reducing the appearance of wrinkles, improving skin elasticity, and promoting a firmer, more youthful complexion.
Oligopeptide-24 works by upregulating the expression of epidermal growth factor (EGF), activating fibroblasts, and enhancing the skin's natural repair mechanisms, making it a valuable ingredient in anti-aging and skin-rejuvenation formulations.

Oligopeptide-24 is a synthetic biomimetic peptide that stimulates skin cell proliferation by upregulating EGF (Epidermal Growth Factor) expression.
Oligopeptide-24 mimics a key component in regulating the renewal of all skin structures: epidermal and dermal cells, hyaluronic acid molecules, collagen fibers, elastin, and fibronectin.

Oligopeptide-24 demonstrated upregulation of cell growth and migration, cell survival, extracellular matrix expression, and the expression of a specific type of growth factor in skin cell lines.
Oligopeptide-24 smoothes fine lines and wrinkles, revealing a youthful skin appearance.

A scientific study showed an increase in EGF concentration in fibroblast cells after 72 hours of treatment with Oligopeptide-24 in serum-free culture conditions.
Additionally, Oligopeptide-24 demonstrated positive regulation of CG-EDP3, hyaluronic acid, and fibronectin expression.
Oligopeptide-24 was observed that oligopeptide-24 increased hyaluronic acid (3-fold) and elastin (1.3-fold) expression in fibroblast cells in a dose-dependent manner.

Oligopeptide-24 is also used as an anabolic "fat-burning" peptide in injectable preparations.
Due to its noticeable beneficial effects, Oligopeptide-24 is used in various anti-aging products for skin and body care.

Oligopeptide-24 is a synthetic biomimetic peptide composed of 13 amino-acid residues, including arginine, aspartic acid, cysteine, isoleucine, glutamic acid, glycine, methionine, and tyrosine.
Oligopeptide-24 is primarily used as a skin-conditioning ingredient in cosmetic and personal-care formulations.

Oligopeptide-24 is commonly incorporated into anti-aging, firming, moisturizing, and skin-renewal products because of its potential to support fibroblast activity and components associated with skin elasticity and hydration.
Oligopeptide-24 is a 13 amino acids biomimetic peptide with skin repair effect.

Oligopeptide-24 upregulates expression of elastin and hyaluronic acid and increases fibroblast activity.
Oligopeptide-24 can be used in cosmetics as an anti-wrinkle and firming agent.

Oligopeptide-24 regulates cell growth and promotes growth.
Oligopeptide-24 stimulates the metabolism of skin cells, promoting collagen and elastin generation.

Oligopeptide-24 can reduce skin redness, swelling, and sensitivity by inhibiting inflammatory reactions.
Oligopeptide-24 is suitable for use in anti-wrinkle and anti-aging cosmetics.

Oligopeptide-24 is a synthetic biomimetic peptide that stimulates skin cell proliferation by up-regulation of EGF (Epidermal Growth Factor) expression.
Oligopeptide-24 mimics a key component in the regulation of the renewal of all skin structures: epidermal and dermal cells, hyaluronic acid molecules, collagen fibers, elastin, and fibronectin. BiologicalSciences

Oligopeptide-24 demonstrated upregulation of cell growth and migration, cell survival, extracellular matrix expression, and specific growth factor expression in skin cell lines.
Oligopeptide-24 smooths fine lines and wrinkles, exposing a youthful skin appearance.

A scientific study showed that EGF concentration increased in fibroblast cells after 72 hours of Oligopeptide-24 treatment in a serum-free culture condition.
In addition, CG-EDP3 showed positive regulation of Hyaluronic acid and fibronectin expression.
Increased expression of hyaluronic acid (3-fold) and Elastin (1.3-fold) was observed in a dose-dependent manner with Oligopeptide-24 in fibroblast cells.

Applications of Oligopeptide-24:
Oligopeptide-24 is used in anti-aging creams, facial serums, eye-care products, moisturizers, and skin-repair formulations.
Oligopeptide-24 is incorporated into cosmetic products designed to support skin firmness, elasticity, smoothness, and overall skin conditioning.

Oligopeptide-24 may also be used in rejuvenating, wrinkle-care, and intensive treatment formulations where peptide-based active ingredients are desired.
Oligopeptide-24 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient.

Applications in Cosmetic Formulations:

Anti-Aging Products:
The primary application of Oligopeptide-24 is in anti-aging skincare formulations, where it serves as an active ingredient targeting multiple signs of skin aging.

Oligopeptide-24's biological activities make it particularly valuable for addressing:

Formulation Synergies:
In cosmetic formulations, Oligopeptide-24 can be strategically combined with complementary ingredients to enhance its efficacy.

According to skincare formulation guidelines, Oligopeptide-24 pairs particularly well with:
Hyaluronic acid for added hydration and synergistic effects on skin plumping
Niacinamide to enhance skin barrier function and provide additional anti-aging benefits
Vitamins such as B3, Provitamin B5, and Vitamin E to provide antioxidant protection and support skin repair processes

These combinations create comprehensive anti-aging formulations that address multiple aspects of skin aging simultaneously.

Application Recommendations:
Skincare products containing Oligopeptide-24 are typically recommended for evening application as part of a nighttime skincare routine.
This timing aligns with the skin's natural regeneration cycle, which is more active during sleep.
Oligopeptide-24 is best applied before moisturizing to ensure optimal penetration into the skin and maximize its beneficial effects.

Chemical Structure and Properties of Oligopeptide-24:

Molecular Composition:
Oligopeptide-24 is a precisely engineered synthetic peptide consisting of 13 amino acids.
Oligopeptide-24's composition includes arginine, aspartic acid, cysteine, isoleucine, glutamic acid, glycine, methionine, and tyrosine.
These amino acids are arranged in a specific sequence to optimize the peptide's biological activity and interactions with target receptors in the skin.

Amino Acid Sequence:
The exact sequence of Oligopeptide-24 is Cys-Met-Tyr-Ile-Glu-Gly-Gly-Gly-Gly-Arg-Gly-Asp-Gly, which can be shortened to CMYIEGGGGRGDG.
This precise arrangement is crucial for its biological effects and receptor recognition, allowing it to effectively mimic natural peptide signals involved in skin regeneration processes.

Stability and Reactivity of Oligopeptide-24:

Chemical Stability:
Stable under recommended storage and handling conditions.

Reactivity:
Low reactivity under normal conditions.

Conditions to Avoid:
Excessive heat, moisture, prolonged light exposure, and incompatible materials.

Incompatible Materials:
Strong oxidizing agents, strong acids, and strong bases.

Handling and Storage of Oligopeptide-24:

Safe Handling:
Avoid generating dust and unnecessary contact with eyes and skin.

Storage Conditions:
Store tightly closed in a cool, dry, well-ventilated place, protected from heat, moisture, and direct sunlight.

First Aid Measures of Oligopeptide-24:

Inhalation:
Move the affected person to fresh air and seek medical attention if discomfort persists.

Skin Contact:
Wash thoroughly with soap and water.

Eye Contact:
Rinse cautiously with plenty of water for several minutes and obtain medical attention if irritation continues.

Ingestion:
Rinse mouth and seek medical advice if symptoms occur.

Firefighting Measures of Oligopeptide-24:

Suitable Extinguishing Media:
Use water spray, dry chemical, foam, or carbon dioxide as appropriate for the surrounding fire.

Specific Hazards:
Thermal decomposition may produce irritating gases and fumes.

Protective Equipment:
Firefighters should use suitable protective clothing and self-contained breathing apparatus when necessary.

Accidental Release Measures of Oligopeptide-24:

Personal Precautions:
Avoid dust formation and contact with eyes or skin.

Cleanup Methods:
Carefully collect spilled material into a suitable container and clean the affected area thoroughly.

Environmental Precautions:
Prevent unnecessary release into drains and surface waters.

Exposure Controls/Personal Protective Protection of Oligopeptide-24:

Engineering Controls:
Provide adequate general or local ventilation where dust may be generated.

Eye Protection:
Safety glasses or protective goggles.

Hand Protection:
Suitable protective gloves.

Skin Protection:
Wear appropriate protective clothing.

Respiratory Protection:
Use suitable particulate respiratory protection when significant dust exposure cannot be adequately controlled.

Identifiers of Oligopeptide-24:
Synonym: CG-EDP3
CAS Number: 1018685-16-9
Molecular Formula: C50H78N16O19S2
Molecular Weight: Approximately 1271.38 g/mol
Chemical Type: Synthetic oligopeptide

Chemical Name: OLIGOPEPTIDE-24
CAS No.: 1018685-16-9
Molecular Formula: C50H78N16O19S2
Molecular weights: 1271.38
Appearance: White to off-white powder
Content: ≥98%

Product Name: OLIGOPEPTIDE-24
CAS: 1018685-16-9
MF: C50H78N16O19S2
MW: 1271.38

Category: Cosmetic Peptides
Molecular Formula: C50H78N16O19S2
Molecular Weight: 1271.38
Appearance: White to off-white solid
Storage: Store at -20 °C

Density: 1.54±0.1 g/cm3
Sequence: CMYIEGGGGRGDG
Solubility: Soluble in DMSO
InChI: InChI=1S/C50H78N16O19S2/c1-4-25(2)42(66-48(84)32(16-26-7-9-27(67)10-8-26)65-47(83)31(13-15-87-3)63-43(79)28(51)24-86)49(85)64-30(11-12-39(73)74)45(81)58-20-36(70)56-18-34(68)55-19-35(69)57-21-37(71)61-29(6-5-14-54-50(52)53)44(80)59-22-38(72)62-33(17-40(75)76)46(82)60-23-41(77)78/h7-10,25,28-33,42,67,86H,4-6,11-24,51H2,1-3H3,(H,55,68)(H,56,70)(H,57,69)(H,58,81)(H,59,80)(H,60,82)(H,61,71)(H,62,72)(H,63,79)(H,64,85)(H,65,83)(H,66,84)(H,73,74)(H,75,76)(H,77,78)(H4,52,53,54)/t25-,28-,29-,30-,31-,32-,33-,42-/m0/s1
InChI Key: KETLMQUWYBBGQR-ZXVPBAOPSA-N
SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)N

Chem/IUPAC Name: Oligopeptide-24 is the synthetic peptide containing 13 amino acids consisting of arginine, aspartic acid, cysteine, isoleucine, glutamic acid, glycine, methionine, and tyrosine
COSING REF No: 83566

CAS No.: 1018685-16-9
Chemical Name: OLIGOPEPTIDE-24
CBNumber: CB43135071
Molecular Formula: C50H78N16O19S2
Molecular Weight: 1271.38

Properties of Oligopeptide-24:
Appearance: White to off-white powder
Odor: Characteristic or nearly odorless
Solubility: Soluble or dispersible in water
Molecular Weight: Approximately 1271.38 g/mol
Molecular Formula: C50H78N16O19S2
Physical Form: Peptide powder

Density: 1.54±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka: 3.16±0.10(predicted)
form: Solid
color: White to off-white
Sequence: Cys-Met-Tyr-Ile-Glu-Gly-Gly-Gly-Gly-Arg-Gly-Asp-Gly
Cosmetics Ingredients Functions: SKIN CONDITIONING

density : 1.54±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka: 3.16±0.10(predicted)
form : Solid
color : White to off-white
Sequence: Cys-Met-Tyr-Ile-Glu-Gly-Gly-Gly-Gly-Arg-Gly-Asp-Gly
Cosmetics Ingredients Functions: SKIN CONDITIONING