ORTHO PHENYL PHENOL

Ortho-Phenylphenol is a white crystalline solid with a mild aromatic odor. 
It is slightly soluble in water but more soluble in organic solvents like alcohols and acetone.
The compound is primarily known for its antifungal and antibacterial properties.
 
Cas Number
90-43-7

Synonyms
2-Phenylphenol,o-Phenylphenol,o-Phenylphenol (synonym),Benzenemethanol, 2-phenyl-, 2-Hydroxybiphenyl
 
Introduction
Definition: Ortho Phenyl Phenol (OPP), also known as 2-Phenylphenol, is an aromatic organic compound with fungicidal properties. 
It is primarily used as a preservative and disinfectant.
Historical Development: Overview of how OPP was first discovered and its development for industrial and agricultural use.
Relevance: Its widespread use in agriculture, household products, and as an antimicrobial agent.
 
Chemical Properties
Molecular Formula: C12H10O.
Molecular Structure: Detailed structure with bond angles, ring configuration, and positions of functional groups.
Physical Properties: Melting point, boiling point, density, and state at room temperature.
Solubility: Solubility in water, ethanol, and other organic solvents.
Chemical Behavior: How OPP reacts with acids, bases, and other chemicals.
Reactivity: Stability in different environments (heat, light, humidity).
Spectral Data: IR, NMR, and Mass Spectrometry profiles of OPP to analyze its molecular structure.
 
Production Methods
Raw Materials: Detailed description of the starting materials used to produce Ortho Phenyl Phenol (e.g., phenol and benzene).
 
Synthesis: Various methods of synthesizing OPP, including Friedel-Crafts acylation and other chemical reactions.
Industrial Scale Production: Overview of large-scale production methods, catalysts, and processes used in factories.
Economic Considerations: Costs and sustainability of production methods.
 
Applications
Agriculture: Its role as a fungicide, especially for crops like fruits, vegetables, and grains. Application methods, efficacy, and regulatory considerations.
Disinfectants and Preservatives: Use in cleaning products, surface disinfectants, and personal care products. Benefits in preventing microbial growth.
Healthcare and Medical Uses: Its role as an antiseptic and preservative in pharmaceuticals.
Industrial Applications: Utilization in the manufacturing of coatings, plastics, and other chemical products.
Food and Beverage: How OPP is used as a preservative in food products and its regulatory status in different regions.
 
Benefits and Drawbacks
Benefits:
Effectiveness as a Fungicide: Comparison with other fungicides in terms of performance, spectrum of activity, and ease of application.
Broad-Spectrum Activity: Its ability to target a wide range of pathogens, especially fungi.
Stability and Longevity: How it remains effective over long periods.
Drawbacks:
Toxicity: Potential health hazards for humans and animals, including acute toxicity and long-term exposure risks.
Environmental Concerns: Bioaccumulation in soil and water and its impact on aquatic life.
Resistance: Development of fungal resistance to OPP and the potential for reduced efficacy.
Regulatory Restrictions: Limits on the concentration of OPP in various products due to its toxicity.
 
Environmental Impact
Degradation in the Environment: How OPP breaks down in the environment (e.g., in water, soil, and air).
Bioaccumulation: Potential for OPP to accumulate in living organisms, affecting wildlife and ecosystems.
Impact on Non-target Organisms: Effects on beneficial species such as pollinators, earthworms, and other organisms.
Waste Management: Methods for disposing of or neutralizing OPP waste in industrial settings to prevent contamination.
Regulations: Global standards for OPP release into the environment and its controlled use in agriculture.
 
Alternatives to Ortho Phenyl Phenol
Other Fungicides: A comparison between OPP and other fungicides like copper sulfate, sodium bicarbonate, or sulfur.
Antiseptic Agents: Comparison with alternative antiseptics like chlorine-based compounds, iodine, or hydrogen peroxide.
Environmental Alternatives: Safer alternatives for agricultural and industrial uses that have less environmental impact.
Efficacy and Cost-Effectiveness: Evaluating alternatives in terms of cost, effectiveness, and safety for both humans and the environment.

SAFETY INFORMATION ABOUT ORTHO PHENYL PHENOL

 
 
 
First aid measures:
Description of first aid measures:
General advice:
Consult a physician. 
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
 
If inhaled:
If breathed in, move person into fresh air. 
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately. 
Wash off with soap and plenty of water.
Consult a physician.
 
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
 
If swallowed:
Do NOT induce vomiting. 
Never give anything by mouth to an unconscious person. 
Rinse mouth with water. 
Consult a physician.
 
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
 
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. 
 
Avoid breathing vapours, mist or gas. 
Evacuate personnel to safe areas.
 
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
 
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste. 
Keep in suitable, closed containers for disposal.
 
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
 
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place. 
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
 
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
 
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles. 
Faceshield (8-inch minimum). 
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
 
Skin protection:
Handle with gloves. 
Gloves must be inspected prior to use. 
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product. 
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. 
Wash and dry hands.
 
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
 
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. 
 
If the respirator is the sole means of protection, use a full-face supplied air respirator. 
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. 
Do not let product enter drains.
Discharge into the environment must be avoided.
 
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions. 
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
 
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company. 
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product