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P-CHLOROCRESOL

P-CHLOROCRESOL = 4-CHLORO-3-METHYLPHENOL


CAS Number: 59-50-7
EC Number: 200-431-6
MDL Number: MFCD00002323
Linear Formula: ClC6H4OH

White to off white crystalline powderbp-Chlorocresol is the organic compound with the formula ClC6H4OH. 
p-Chlorocresol is a monochlorinated m-cresol. 
p-Chlorocresol is prepared by the chlorination of m-cresol.
Freely soluble in organic solvent, ether, ketones and strong base aqueous solution, and completely soluble in oil.


Friendly to environment, formaldehyde-free, easily degradable.
Well compatibility with anionic surfactant, non-ionic surfactant and emulgator. 
Good synergistic effect with other antiseptic and bactericide.
White to slightly pink crystals.


Odorless or slightly phenolic odor.
Soluble in alkalies, organic solvents, fats, and oils
p-Chlorocresol is a monochlorinated m-cresol. 
p-Chlorocresol is a white or colorless solid that is only slightly soluble in water. 


p-Chlorocresol is prepared by chlorination of m-cresol.
p-Chlorocresol forms colourless, dimorphous crystals at room temperature and is only slightly soluble in water. 
Ph range of application: 4-12
p-Chlorocresol is the organic compound with the formula ClC6H4OH. 
p-Chlorocresol is a monochlorinated m-cresol. 


A ryanodine receptor agonist. 
p-Chlorocresol has a role as a ryanodine receptor agonist, an antimicrobial agent and a disinfectant. 
p-Chlorocresol is a hydroxytoluene and a member of monochlorobenzenes.
p-Chlorocresol is soluble in water, fatty oil, alkali hydroxide solution and organic solvents such as alcohols, ethers & ketones. 


p-Chlorocresol appears as a pinkish to white crystalline solid with a phenolic odor. 
p-Chlorocresol is a white or colorless solid that is only slightly soluble in water. 
A pinkish to white crystalline solid with a phenolic odor. 
Melting point 64-66°C. 


Soluble in aqueous base. 
p-Chlorocresol is a white or colorless solid that is only slightly soluble in water. 
p-Chlorocresol forms colourless, dimorphous crystals at room temperature and is only slightly soluble in water. 
p-Chlorocresol has a broad and very balanced spectrum of activity covering Gram-positive and Gram-negative bacteria, mould and yeast. 


p-Chlorocresol CAS 59-50-7 or 4-Chloro-3-methylphenol is colorless crystals with phenol odor.
p-Chlorocresol is insoluble in water, soluble in most organic solvents.
p-Chlorocresol with a chemical formula  C7H7ClO appears as a white crystalline powdered with a phenolic odor. 
p-Chlorocresol is not natural, rather made by human being. 


p-Chlorocresol has a broad and very balanced spectrum of activity covering Gram-positive and Gram-negative bacteria, mould and yeast. 
Particularly effective against putrefactive bacteria and therefore suitable for use in products which are difficult to preserve (e.g. protein-based formulations).
p-Chlorocresol is a monochlorinated m-cresol. 
p-Chlorocresol is a white or colorless solid that is only slightly soluble in water. 


As a solution in alcohol and in combination with other phenols, p-Chlorocresol is used as an antiseptic and preservative . 
p-Chlorocresol is also an active ingredient in one registered pest control product which is used as a component in concrete admixtures, while the sodium salt form of chlorocresol is present in two registered pest control products.
p-Chlorocresol is the organic compound with the formula ClC6H4OH. 
p-Chlorocresol is a monochlorinated m-cresol. 


p-Chlorocresol is a white or colorless solid that is only slightly soluble in water. 
As a solution in alcohol and in combination with other phenols, p-Chlorocresol is used as an antiseptic and preservative. 
Belongs to the class of organic compounds known as meta cresols. 
These are aromatic compounds containing a meta-cresol moiety, which consists of a benzene ring bearing a methyl group and a hydroxyl group at ring positions 1 and 3, respectively.


p-Chlorocresol is classified as preservative.
p-Chlorocresol is a biocide, which is colorless crystalline compound. 
p-Chlorocresol has role antimicrobial agent.
p-Chlorocresol has role disinfectant.


p-Chlorocresol has role ryanodine receptor agonist.
p-Chlorocresol as know as p-Chlorocresol, is the organic compound with the formula ClC6H4OH. 
p-Chlorocresol is a monochlorinated m-cresol. 
p-Chlorocresol is a white or colorless solid that is only slightly soluble in water. 


p-Chlorocresol is dissolved in organic solvents or nonionic surfactants such as L-64 and then matched with other ingredients. 
White or of- white powder or crystlline power,odorless.
Very soluble in N,N-Dimethylformamide, soluble in methanol, sparingly soluble inglacial acetic acid, very slightly soluble inchloroform, practically insoluble in water.
p-Chlorocresol has a broad and very balanced spectrum of activity covering Gram-positive and Gram-negative bacteria, mould and yeast. 


p-Chlorocresol, also called 4-Chloro-3-methylphenol, is a white to almost white flake. 
p-Chlorocresol is slightly soluble in water(4g/L), easy soluble in organic solvent such as alcohols (96 percent in ethanol), ethers, ketones, etc.
p-Chlorocresol is freely soluble in fatty oils, and dissolves in solutions of alkali hydroxides. 
p-Chlorocresol appears as a pinkish to white crystalline solid with a phenolic odor. 


Melting point is 64-66°C. 
Soluble in aqueous base. 
p-Chlorocresol is a hydroxytoluene that is 3-methylphenol which is substituted by a chlorine at position 4. 
p-Chlorocresol is a hydroxytoluene.


p-Chlorocresol is a monochlorobenzenes.
A hydroxytoluene that is 3-methylphenol which is substituted by a chlorine at position 4. 
A ryanodine receptor agonist.
p-Chlorocresol has a broad and very balanced spectrum of activity covering Gram-positive and Gram-negative bacteria, mould and yeast.
p-Chlorocresol is prepared by chlorination of m-cresol.


p-Chlorocresol is a chlorinated phenol which is used as an antiseptic and preservative. 
For use as a disinfectant such as a hand wash, p-Chlorocresol is commonly dissolved in alcohol in combination with other phenols. 
p-Chlorocresol is the organic compound with the formula ClC6H4OH. 
p-Chlorocresol is a monochlorinated m-cresol. 
p-Chlorocresol is a white or colorless solid that is only slightly soluble in water. 


USES and APPLICATIONS of P-CHLOROCRESOL:
-As a solution in alcohol and in combination with other phenols, p-Chlorocresol is used as an antiseptic and preservative. 
-Tanning Agents
-Topical Antiseptics and Disinfectants
-Adhesives and glues
-Baby cosmetics


-Cooling fluids
-Cosmetics (shampoos and baby cosmetics)
-Creams
-Other fields such as leather, metal machining liquid, concrete, film, glue, textile, oiled, paper, etc.


-p-Chlorocresol is a security and efficient anti-mould antiseptic, which can be used in antibacterial hand soap, shampoo and other healthy products.
-p-Chlorocresol is mainly used as a disinfectant in the field of poultry, and also can be used as an industrial antimildew agent in the fields of leather, adhesives, coatings, papermaking etc.
-p-Chlorocresol is a compound used as an antiseptic, disinfectant and fungicide. 
-p-Chlorocresol is found in creams, topical antiseptics, shampoos, cosmetics and cooling fluids. 


-p-Chlorocresol is also used as an ingredient in various pharmaceutical preparations.
-Inks, paints, and varnishes
-Metalworking fluids
-Packing materials


-Ryanodine receptor agonist:
A ryanodine receptor modulator which activates the receptor. 
Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. 
Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction.


-Antimicrobial agent:
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
-Disinfectant:
An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.


-p-Chlorocresol is also used as a preservative in creams and other preparations for external use which contain water. 
-For use as a disinfectant such as a hand wash, p-Chlorocresol is commonly dissolved in alcohol in combination with other phenols. 
-p-Chlorocresol is a substituted phenol that functions as a cosmetic biocide preservative in skin care and suntan cosmetic formulations.


-For the preservation of adhesives, glues, polymer dispersions and emulsions, metalworking/cutting fluids, dyes, industrial lubricants, pigments and filler suspensions, materials in the building industry (e.g., concrete additives, joint cements), paint and coatings, paper, textile, photo, oil industries and leather at all stages of production.
-Personal care products, antibacterial hand soap, soap, shampoo and healthy products.
-Household & institutional disinfectant and cleansers, Public & hospital Hygiene.


-For the preservation of medical salves and vaccines.
-p-Chlorocresol can be commonly used as a preservative in pharmaceutical products and as an additive to building materials and metal-working fluids.
-Cosmetics
-Creams
-Adhesives and glues


-Cooling fluids
-Corticosteroid creams
-Used as an external germicide. 
-Used as a preservative in paints and inks.


-p-Chlorocresol is used as a preservative in a variety of topical preparations, such as corticosteroid creams and moisturizers and in disinfectants and detergents. 
-p-Chlorocresol is a chlorinated phenol which is used as an antiseptic and preservative. 
-p-Chlorocresol is mainly used as a disinfectant in the field of poultry, and also can be used as an industrial antimildew agent in the fields of leather, adhesives, coatings, papermaking etc.
-Personal care products, such as antibacterial soap, antibacterial shampoo and health care products.


-Other fields such as leather, metal machining liquid, concrete, film, glue, textile, oiled, paper, etc.
-Inks
-Metalworking fluids
-Packing materials


-Paints
-Textile finishes
-Varnishes
-p-Chlorocresol may be used as an analytical standard for the determination of the analyte in water and soil samples by chromatography techniques.


-p-Chlorocresol may be used in certain body creams or lotions and as a non-medicinal ingredient in natural health products and pharmaceuticals.
-Hair care (Shampoos, Conditioners & Styling) 
-Toiletries (Shower & Bath, Oral care...)
-Protections


-Pharmaceutical products
-Tanning agents
-Textile finishes
-Topical antiseptics and disinfectants
-Antibacterial agent


-Preservative
-p-Chlorocresol is frequently used in personal care products, leather, metal machining liquid, concrete, film, gluewater, textile, oiled, paper, etc.
-p-Chlorocresol is a security, efficient, anti-mould antiseptic, anti-mildew agent.
-p-Chlorocresol is a security, efficient, anti-mould antiseptic, anti-mildew agent. 


-Particularly effective against putrefactive bacteria and therefore suitable for use in products which are difficult to preserve (e.g. protein-based formulations).
-p-Chlorocresol is an activator of ryanodine receptor.
-p-Chlorocresol possesses disinfectant and antiseptic properties. 
-p-Chlorocresol is used in various preparations for skin disinfection and wounds. 


-Research chemicals
-Raw material chemical
-Research chemical
-Pharmaceutical intermediate


-Chemical and pharmaceutical intermediates
-Biocides
-For the preservation of thickener solutions, adhesives (including protein-based formulations), concrete additives, metalworking fluids, textile print thickeners, leather etc. 
-p-Chlorocresol of disinfectants is used in hospitals, doctor’s offices, industry, institutions and sheds.


-Concrete additive
-Construction material
-Cosmetics
-Fungicidal treatment of bitumen isolation coverings


-Fungicidal treatment of construction material
-Material protection
-Antibacterial agent
-Preservative


-Pharmaceutical intermediate
-Research chemicals
-Raw material chemical
-Research chemical


-Industrial/Fine Chemicals
-Fluorobenzene
-p-Chlorocresol is a highly effective germicide and fungicide. 
-p-Chlorocresol is widely used in personal care products, film, adhesives or glue, textile, inks, paints, paper and leather. 


-p-Chlorocresol is effectively to control the growth of a wide spectrum of microorganisms - bacteria, mould and fungi. 
-For use as a disinfectant such as a hand wash, p-Chlorocresol is commonly dissolved in alcohol in combination with other phenols. 
-Used as a disinfectant, germicide, preservative, and fungicide.
-p-Chlorocresol is a compound used as an antiseptic, disinfectant and fungicide. 


-p-Chlorocresol is found in creams, topical antiseptics,
shampoos, cosmetics and cooling fluids. 
-p-Chlorocresol is also used as an ingredient in various pharmaceutical preparations.
-Biocides
-Highly Purified Reagents


-Other Categories
-Zone Refined Products
-Pharmaceutical intermediates
-Chemical and pharmaceutical intermediates


-Aromatic Phenols
-Organics
-Phenoles and thiophenoles
-p-Chlorocresol is used for many products, from cosmetics, personal care to leather products, as a preservative and germicide. 


-Personal care products, antibacterial hand soap, soap, shampoo and healthy products.
-Household & institutional disinfectant and cleansers, Public & hospital Hygiene.
-Other fields such as leather, metal machining liquid, concrete, film, glue, textile, oiled, paper, etc.
-Industrial/Fine Chemicals


-Fluorobenzene
-Highly Purified Reagents
-Other Categories
-Zone Refined Products


-Phenoles and thiophenoles
-Aromatic Phenols
-Organics
-p-Chlorocresol is also added to pesticides as p-Chlorocresol acts as a chemical intermediate. 


-Given to p-Chlorocresol's anti-fungal and disinfectant properties, p-Chlorocresol is added into eye drops and hand wash. 
-p-Chlorocresol can be added to all preparations that are meant to be externally used and also contain water.  
-Biocide
-Disinfectant & Antiseptic


-External Germicide
-Preservative
-p-Chlorocresol is mainly used as preservatives and disinfectants.
-Antisepsis and disinfection. 
-p-Chlorocresol is used in organic synthesis, such as dyes, film preservatives, etc.


-Protein shampoo and infant cosmetics preservatives. 
-p-Chlorocresol is also used in organic synthetic raw materials, pigment intermediates and film preservatives.
-Bacteriostatic Agent
-Anti-Septic


-Particularly effective against putrefactive bacteria and therefore suitable for use in products which are difficult to preserve (e.g. protein-based formulations).
-For the preservation of thickener solutions, adhesives (including protein-based formulations), concrete additives, metalworking fluids, textile print thickeners, leather etc.
-Cosmetics
-Chloro Cresol Technical Details:
-Glues/ Gums


-Dyes  / Textiles Auxiliary
-Human & Veterinarian Medicinal Products
-Inks
-Leather Goods 
-Leather, Injectable Drug, Disinfectant , Guar Gum preservative

ALTERNATIVE PARENTS of P-CHLOROCRESOL:
-P-chlorophenols 
-Toluenes 
-Chlorobenzenes 
-1-hydroxy-2-unsubstituted benzenoids 

-Aryl chlorides 
-Organooxygen compounds 
-Organochlorides 
-Hydrocarbon derivatives 


SUBSTITUENTS of P-CHLOROCRESOL:
-4-halophenol
-M-cresol
-4-chlorophenol
-Chlorobenzene


-Halobenzene
-1-hydroxy-2-unsubstituted benzenoid
-Toluene
-Aryl halide
-Aryl chloride
-Monocyclic benzene moiety


-Organohalogen compound
-Organic oxygen compound
-Organochloride
-Organooxygen compound
-Hydrocarbon derivative
-Aromatic homomonocyclic compound


PHYSICAL and CHEMICAL PROPERTIES of P-CHLOROCRESOL:
Molecular Weight: 142.58
XLogP3: 3.1
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 142.0185425
Monoisotopic Mass: 142.0185425
Topological Polar Surface Area: 20.2 Ų
Heavy Atom Count: 9


Formal Charge: 0
Complexity: 94.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes


Appearance: Off White Crystals
Boiling Point: 235 °C
Density: 1.228 g/cm3
Melting Point: 63-65 °C
Molar Mass: 142.58 g/mol
PG: 2
Related Compounds:Chloroxylenol
Solubility: 4 g/l


Water Solubility: 3.93 g/L
logP: 2.74    
logP: 2.79    
logS: -1.6    
pKa (Strongest Acidic): 9.08    
pKa (Strongest Basic): -6.3    
Physiological Charge: 0    
Hydrogen Acceptor Count: 1    
Hydrogen Donor Count: 1    
Polar Surface Area: 20.23 Ų    


Rotatable Bond Count: 0    
Refractivity: 37.88 m³·mol⁻¹    
Polarizability: 14.03 ų    
Number of Rings: 1    
Bioavailability: 1    
Rule of Five: Yes    
Ghose Filter: Yes    
Veber's Rule: Yes    
MDDR-like Rule: Yes


FIRST AID MEASURES of P-CHLOROCRESOL:
-General Information: 
Immediately remove any clothing contaminated by the product. 
Consult a physician.

-Inhalation: 
Move person to fresh air. 
Obtain medical aid.

-Skin contact: 
Immediately flush skin with running water for at least 15 minutes while removing contaminated clothing and shoes. 
Wash clothing before reuse. 
Obtain medical aid immediately.

-Eye contact: 
Immediately flush open eyes with running water for at least 15 minutes. 
Obtain medical aid immediately.

-Ingestion: 
Rinse mouth with water. 
Obtain medical aid immediately.

-Indication of any immediate medical attention and special treatment needed: 
No further information available.


ACCIDENTAL RELEASE MEASURES of P-CHLOROCRESOL:
-Environmental precautions: 
Do not let product enter drains, other waterways, or soil.

-Methods and materials for containment and cleaning up: 
Prevent further leak or spill if safe to do so. 
Vacuum, sweep up, or absorb with inert material and place into a suitable disposal container.
Consult local regulations for disposal.


FIRE FIGHTING MEASURES of P-CHLOROCRESOL:
-Suitable extinguishing media: 
Use water spray, dry chemical, carbon dioxide, or chemical foam.


EXPOSURE CONTROLS/PERSONAL PROTECTION of P-CHLOROCRESOL:
-Exposure limits:
*OSHA PEL: Not available.
*NIOSH REL: Not available.
*ACGIH TLV: Not available.

-Appropriate engineering controls: 
Wash hands before breaks and immediately after handling the product. 
Facilities storing or utilizing this material should be equipped with an eyewash fountain. 

-Personal protection:
*Eyes: 
Use safety glasses.

*Skin and body: 
At the minimum, wear a laboratory coat and close-toed footwear.


HANDLING and STORAGE of P-CHLOROCRESOL:
-Precautions for safe handling: 
Wash hands thoroughly after handling.
Wear suitable protective clothing, gloves, and eye/face protection. 
Keep container tightly closed. 
Do not eat, drink, or smoke while handling.

-Conditions for safe storage, including any incompatibilities: 
Store in a tightly-closed container when not in use. 


STABILITY and REACTIVITY of P-CHLOROCRESOL:
-Reactivity: 
Not available.
-Chemical stability: 
Stable under recommended temperatures and pressures.


SYNONYMS:
p-Chloro-m-cresol
4-Chloro-3-methylphenol
p-Chlorocresol 
Phenol,4-chloro-3-methyl-
4-Chloro-3-methylphenol
p-Chlorocresol
Para Chloro Meta Cresol 
m-Cresol,4-chloro-
1-Chloro-2-methyl-4-hydroxybenzene
2-Chloro-5-hydroxytoluene
3-Methyl-4-chlorophenol
4-Chloro-5-methylphenol
4-Chloro-m-cresol
6-Chloro-3-hydroxytoluene
Baktolan
Candaseptic
Neopredisan
Ottafact
Rasen-Anicon
p-Chloro-m-cresol
para-Chloro-meta-cresol
4-chloro-1-hydroxy-3-methylbenzene
4-chloro-3-methyl-pheno
4-chloro-3-methylphenol(p-chlorocresol)
4-Chloro-5-methylphenol
4-chloro-m-creso
PARA CHLORO META CRESOL
PCMC
P-CHLORO-M-CRESOL
Phenol, 4-chloro-3-methyl-
Parol
p-Chlorocresol
Ottafact
Baktol
4-Chloro-3-cresol
Candaseptic
Baktolan
Parmetol
Peritonan
Raschit
Aptal
Rasen-Anicon
4-Chloro-5-methylphenol
Preventol CMK
Raschit K
p-Chlor-m-cresol
2-Chloro-5-hydroxytoluene
6-Chloro-3-hydroxytoluene
3-METHYL-4-CHLOROPHENOL
2-Chloro-hydroxytoluene
Chlorocresolum
4-Chloro-3-methyl phenol
m-Cresol, 4-chloro-
Rcra waste number U039
NSC 4166
para-Chloro-meta-cresol
1-Chloro-2-methyl-4-hydroxybenzene
2-Chloro-5-hydroxytoluene
2-Chloro-5-Hydroxytoluene, 4-Chloro-m-Cresol, Chlorocresol
2-Chloro-hydroxytoluene

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