PRODUCTS

p-TOLUENESULFONYL ISOCYANATE

CAS NUMBER: 4083-64-1

EC NUMBER: 223-810-8

MOLECULAR FORMULA: C8H7NO3S

MOLECULAR WEIGHT: 197.21

IUPAC NAME: 4-methyl-N-(oxomethylidene)benzenesulfonamide

p-Toluenesulfonyl Isocyanate undergoes palladium-catalyzed bis-allylation reaction with allylstannanes and allyl chlorides.
p-Toluenesulfonyl Isocyanate is a reagent used to prepare acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides

p-Toluenesulfonyl Isocyanate undergoes palladium-catalyzed bis-allylation reaction with allylstannanes and allyl chlorides.
p-Toluenesulfonyl Isocyanate is a Colorless liquid

Application:
p-Toluenesulfonyl Isocyanate has been used as :
-derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS

-derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC

-as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides

p-Toluenesulfonyl Isocyanate is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides.
-p-Toluenesulfonyl Isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS.
p-Toluenesulfonyl Isocyanate is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.

p-Toluenesulfonyl Isocyanate undergoes palladium-catalyzed bis-allylation reaction with allylstannanes and allyl chlorides
p-Toluenesulfonyl Isocyanate as a novel derivatization reagent to enhance the electrospray ionization and its application in the determination of two stereo isomers of 3-hydroxyl-7-methyl-norethynodrel in plasma

p-Toluenesulfonyl Isocyanate (PTSI) is sulfonyl isocyanate by VanDeMark Chemical.
p-Toluenesulfonyl Isocyanate Acts as a moisture scavenger.

Urethane systems utilizing PTSI can be applied under the most demanding humidity, dew point or temperature conditions and still guarantee the best corrosion resistance.
p-Toluenesulfonyl Isocyanate's reactivity towards active hydrogen atoms makes it useful as a scavenger for water and other isocyanate reactive groups such as free acid in powdered aluminum alkanoates and active hydrogen present in carbon black pigments.

p-Toluenesulfonyl Isocyanate (PTSI) is suitable for the formulation of urethane-based coatings and UV inks.
p-Toluenesulfonyl Isocyanate is a reagent used to prepare acetylated syn-1,2-diols.

p-Toluenesulfonyl Isocyanate is used in:
-polyurethane coatings

-sealants

-adhesives

-as a stabilizer for organic isocyanates

-as a chemical intermediate.

p-Toluenesulfonyl Isocyanate is used to formulate adhesives-sealants
p-Toluenesulfonyl Isocyanate is used to formulate paints-coatings-thinners

p-Toluenesulfonyl Isocyanate is used as an intermediate for pharmaceuticals
p-Toluenesulfonyl Isocyanate has been used to react with a prepolymer with the OH-functionality.

p-Toluenesulfonyl Isocyanate is used as an intermediate for medicine and moisture scavengers used in urethane applications.
p-Toluenesulfonyl Isocyanate was found that silyl enol ethers reacted with p-toluenesulfonyl isocyanate to afford either N-sulfonyl-2-silyloxycycloalkanecarboxamides or N-sulfonyl-4-silyloxy-2-azetidinones.

Both adducts were easily hydrolyzed to the corresponding N-sulfonyl-2-oxoalkanecarboxamides.
P-Toluenesulfonyl Isocyanate is clear

p-Toluenesulfonyl Isocyanate has a colorless liquid form.
p-Toluenesulfonyl Isocyanate is insoluble in water

P-Toluenesulfonyl Isocyanate (PTSI) can be used as Agent.
p-Toluenesulfonyl Isocyanate can be used as solvent and filler.

p-Toluenesulfonyl Isocyanate can be like pigment
p-Toluenesulfonyl Isocyanate is an effective ingredient

This cure, which is a traditional two-component polyurethane coating system, is applied wet.
In addition, P-Toluenesulfonyl Isocyanate (PTSI) is also a stabilizer.

butyl acts as a purifier.
Double isocyanate can be used to prevent its deterioration or discoloration.

PHYSICAL PROPERTIES:

-Molecular Weight: 197.21

-XLogP3-AA: 2.7

-Exact Mass: 197.01466426

-Monoisotopic Mass: 197.01466426

-Topological Polar Surface Area: 72 Å²

-Physical Description: Liquid

-Melting Point: 5°C

-Boiling Point: 144 °C

-Density: 1.291 g/mL

-Vapor Pressure: 1 mm Hg

-Refractive index: n20/D 1.534(lit.)

-Flash Point: >230 °F

-Specific Gravity: 1.291.291

-Sensitive: Moisture Sensitive

P-Toluenesulfonyl Isocyanate (PTSI) c is a solvent, filler.
p-Toluenesulfonyl Isocyanate reacts with water to produce sulfonamides.

p-Toluenesulfonyl Isocyanate can be used in the paint making process
p-Toluenesulfonyl Isocyanate is usually the alkyl isocyanate and aryl isocyanate are passed through the reaction, not the secondary and ordinary solvents.

In addition, p-Toluenesulfonyl Isocyanate has a structure that does not cause yellowing.
P-Toluenesulfonyl Isocyanate (PTSI) can be used for Polyurethane coating.

p-Toluenesulfonyl Isocyanate acts as an anti-yellowing agent on surfaces such as foam.
p-Toluenesulfonyl Isocyanate is used in the pharmaceutical industry.

CHEMICAL PROPERTIES:

-Heavy Atom Count: 13

-Formal Charge: 0

-Complexity: 303

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Hydrogen Bond Donor Count: 0

-Hydrogen Bond Acceptor Count: 4

-Rotatable Bond Count: 2

p-Toluenesulfonyl Isocyanate is often used as a pharmaceutical intermediate.
P-Toluenesulfonyl Isocyanate (PTSI) has high reactivity.

so the application and operation should be especially careful.
P-Toluenesulfonyl Isocyanate (PTSI) reacts rapidly with water.

p-Toluenesulfonyl Isocyanate also reacts with:
-alcohol

-Amine

-acid

-alkali

By reaction p-Toluenesulfonyl Isocyanate can produce a large number of gases in a very short time.
for example, moisture builds up inside the container, which can cause the container (even a closed container) to burn.

STORAGE:

p-Toluenesulfonyl Isocyanate should be stored in closed containers.
p-Toluenesulfonyl Isocyanate should be kept in its original packaging.

p-Toluenesulfonyl Isocyanate should be stored in a dry environment.
This substance is sensitive to moisture.
In good condition, p-Toluenesulfonyl Isocyanate has a shelf life of at least six months.

p-Toluenesulfonyl Isocyanate is used to formulate adhesives-sealants
p-Toluenesulfonyl Isocyanate is used to formulate paints-coatings-thinners

p-Toluenesulfonyl Isocyanate is used as an intermediate for pharmaceuticals
p-Toluenesulfonyl Isocyanate has been used to react with a prepolymer with the OH-functionality.

p-Toluenesulfonyl Isocyanate is used to formulate adhesives-sealants
p-Toluenesulfonyl Isocyanate is used to formulate paints-coatings-thinners

p-Toluenesulfonyl Isocyanate is used as an intermediate for pharmaceuticals
p-Toluenesulfonyl Isocyanate has been used to react with a prepolymer with the OH-functionality.

p-Toluenesulfonyl Isocyanate is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides.
p-Toluenesulfonyl Isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS.
p-Toluenesulfonyl Isocyanate is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.

p-Toluenesulfonyl Isocyanate (PTSI) is sulfonyl isocyanate by VanDeMark Chemical.
p-Toluenesulfonyl Isocyanate acts as a moisture scavenger.

SYNONYMS:

Tosyl isocyanate
p-Toluenesulfonyl isocyanate
4-Methylbenzenesulfonyl isocyanate
p-Toluenesulphonyl isocyanate
Benzenesulfonyl isocyanate, 4-methyl-
4-methyl-N-(oxomethylidene)benzenesulfonamide
p-Tolylsulfonyl isocyanate
p-Toluenesulfonic acid, anhydride with isocyanic acid
p-TOLUENE SULFONYL ISOCYANATE
p-toluenesulfonylisocyanate
4-Methylbenzene-1-sulphonyl isocyanate
Tosylisocyanate
(4-methylphenyl)sulfonylisocyanate
p-Tosyl isocyanate
TsNCO
4-methylbenzene-1-sulfonyl isocyanate
p-tolylsulfonyl-isocyanate
Sulfone, isocyanato tolyl
p-toluenesulphonylisocyanate
p-Toluensulfonyl isocyanate
p-toluene sulfonylisocyanate
4-Toluenesulfonyl isocyanate
p-toluene-sulfonyl isocyanate
para-toluenesulfonylisocyanate
4-Isocyanatosulphonyltoluene,
p-toluene sulphonyl isocyanate
para-toluene sulfonylisocyanate
4-toluene-sulphonyl isocyanate
p-Methylphenylsulfonyl isocyanate
4-Methylphenylsulfonyl isocyanate
4-Methylphenylsulphonyl isocyanate
4-methyl-benzenesulfonyl isocyanate
p-Toluenesulfonyl isocyanate, 96%
4-methyl-N-(oxo-methylene)-benzenesulfonamide