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PALATINOL IC

Palatinol IC is an odorless plasticizer with the molecular formula C16H22O4.
Palatinol IC is a phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of isobutanol.
Palatinol IC belongs to the class of organic compounds known as benzoic acid esters.

CAS Number: 84-69-5
EC Number: 201-553-2
Chemical formula: C16H22O4
Molar mass: 278.348 g·mol−1

Synonyms: Bis(2-methylpropyl) benzene-1,2-dicarboxylate, Diisobutyl phthalate, Di-iso-butyl phthalate, Di(i-butyl)phthalate, Diisobutyl ester of phthalic acid, 1,2-benzenedicarboxylic acid, Bis(2-methylpropyl)ester, Di(isobutyl) 1,2-benzenedicarboxylate, Isobutyl-O-phthalate, DIBP, DiBP, Palatinol IC, DIISOBUTYL PHTHALATE, 84-69-5, DIBP, Palatinol IC, Isobutyl phthalate, Phthalic Acid Diisobutyl Ester, Hexaplas M/1B, Kodaflex DIBP, Di-iso-butyl phthalate, Phthalic acid, diisobutyl ester, Di(i-butyl)phthalate, 1,2-Benzenedicarboxylic acid, bis(2-methylpropyl) ester, Diisobutylester kyseliny ftalove, NSC 15316, bis(2-methylpropyl) phthalate, isobutyl-o-phthalate, 1,2-Benzenedicarboxylic acid, 1,2-bis(2-methylpropyl) ester, DTXSID9022522, di-2-methylpropyl phthalate, di-l-butyl phthalate (DIBP), IZ67FTN290, CHEBI:79053, NSC-15316, Hatcol DIBP, DTXCID602522, 1,2-benzenedicarboxylic acid bis(2-methylpropyl) ester, 1,2-Benzenedicarboxylic acid, di(2-methylpropyl) ester, Phthalic acid, bis-isobutyl ester, CAS-84-69-5, SMR000112470, di-isobutyl phthalate, CCRIS 6193, HSDB 5247, AI3-04278 (USDA), EINECS 201-553-2, BRN 2054802, UNII-IZ67FTN290, AI3-04278, Isobutyl phthalate (VAN), bis(2-methylpropyl) benzene-1,2-dicarboxylate, EC 201-553-2, Diisobutyl phthalate, 99%, SCHEMBL42787, 4-09-00-03177 (Beilstein Handbook Reference), MLS000516002, MLS002152902, BIDD:ER0640, 1, bis(2-methylpropyl) ester, CHEMBL1370662, HMS2269D07, NSC15316, Tox21_202429, Tox21_300612, MFCD00026480, AKOS015837516, Diisobutyl phthalate (ACD/Name 4.0), WLN: 1Y1&1OVR BVO1Y1&1, NCGC00091360-01, NCGC00091360-02, NCGC00091360-03, NCGC00091360-04, NCGC00254487-01, NCGC00259978-01, FT-0689059, NS00010605, P0298, Q162259, 1,2-bis(2-methylpropyl) benzene-1,2-dicarboxylate, J-503794, 1,2-benzenedicarboxylic acid di(2-methylpropyl) ester, Phthalic acid, bis-isobutyl ester 10 microg/mL in Cyclohexane, Diisobutyl phthalate, certified reference material, TraceCERT(R), 1,2-Benzenedicarboxylic acid, bis(2-methylpropyl) ester, DIBP, Di(i-butyl)phthalate, Di-iso-butyl phthalate, Diisobutylester kyseliny ftalove [Czech], Hatcol DIBP, Hexaplas M/1B, Isobutyl phthalate, Kodaflex DIBP, Palatinol IC, Phthalic acid, diisobutyl ester, Phthaloyl dichloride, MFCD01861606, EINECS 201-553-2, Phthalyl chloride, bis(2-methylpropyl) benzene-1,2-dicarboxylate, Phthalic dichloride, 1,2-Benzenedicarbonyl dichloride, tetraphthaloyl chloride, Phthalic acid dichloride, diisobutyl 1,2-benzenedicarboxylate, 1,2-Benzenedicarboxylic acid, bis(2-methylpropyl) ester, di-l-butyl phthalate (DIBP), Diisobutyl phthalate, phthaloyl chloride, Phthalyl dichloride, benzene-1,2-dicarbonyl dichloride, Phthalic chloride, 1,2-benzene dicarboxylic acid diisobutyl ester, 1,2-benzenedicarboxylic acid, bis(2-methylpropyl) ester, AI3-04278, bisoflex DIBA, bisoflex DIBP, di(isobutyl) 1,2-benzenedicarboxylate, DIBP (=diisobutyl phthalate), diplast B, hatcol DIBP, hexaplas M 18, hexaplas M/1B, hexaplas MIB, isobutyl phthalate, jayflex DIBP, kodaflex DIBP, mollan L, phthalic acid diisobutyl ester, vestinol IB), DBP, ARALDITE RESIN, Butyl phthalate, N-BUTYL PHTHALATE, Dibutyl phthalate, Dibutyl-o-phthalate, Di-n-butyl phthalate, Dibutyl Phthalate(DBP), Diisobutyl Phthalate(DIBP), PHTHALIC ACID DIBUTYL ESTER, Phthalic acid di-n-butyl ester, Dibutyl phthalate,abbreviation, PHTHALIC ACID DI-N-BUTYL ESTER, PHTHALIC ACID, BIS-BUTYL ESTER, dibutyl benzene-1,2-dicarboxylate, O-BENZENEDICARBOXYLIC ACID DIBUTYL ESTER, Benzene-1,2-dicarboxylic acid di-n-butylester, 1,2-Benzenedicarboxylic acid, 1,2-bis(2-methylpropyl) ester, 1,2-Benzenedicarboxylic acid, bis(2-methylpropyl) ester, 1,2-Benzenedicarboxylic acid, di(2-methylpropyl) ester, Bis(2-methylpropyl) phthalate, Di-2-methylpropyl phthalate, DIBP, Diisobutyl phthalic acid, Hexaplas M/1B, Isobutyl phthalate,

Palatinol IC is an organic compound used as a plasticizer in the production of plastic and rubber.
Palatinol IC is a colorless, oily liquid with a slight odor.

Palatinol IC is a phthalate ester, which is a type of chemical compound derived from phthalic acid.
Palatinol IC is a clear liquid.

Palatinol IC is a colorless oily liquid with a slight ester odor.
Palatinol IC is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 tonnes per annum.

Palatinol IC is a phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of isobutanol.
Palatinol IC is oily colorless liquid with a slight ester odor.

Palatinol IC is an odorless plasticizer with the molecular formula C16H22O4.
Palatinol IC is a phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of isobutanol.

Palatinol IC is soluble in ethanol, ether, acetone and benzene.
Palatinol IC belongs to the class of organic compounds known as benzoic acid esters.
These are ester derivatives of benzoic acid.

Palatinol IC is prepared by esterification process of isobutanol and phthalic anhydride.
Palatinol IC is an odorless plasticizer and has excellent heat and light stability.

Palatinol IC is the lowest cost plasticizer for cellulose nitrate.
Palatinol IC has lower density and freezing point than DBP.

Palatinol IC has similar properties as dibutyl phthalate and can be used as a substitute for it.
Palatinol IC is an oily colorless liquid with a slight ester odor.

Palatinol IC is denser than water.
Palatinol IC is insoluble in water.

Palatinol IC is a phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of isobutanol.
Palatinol IC has a role as a plasticiser, a teratogenic agent and a PPAR modulator.

Palatinol IC is a phthalate ester and a diester.
Palatinol IC is functionally related to an isobutanol.

Palatinol IC is an odorless plasticizer and has excellent heat and light stability.
Palatinol IC is the lowest cost plasticizer for cellulose nitrate.
Palatinol IC has lower density and freezing point than DBP (dibutyl phthalate, CAS No.: 84-74-2).

Palatinol IC can substitute dibutyl phthalate (DBP) in most, if not all, applications.
Since Palatinol IC is not chemically bound in the polymer matrix it may outgas or be released upon contact with fluids and fat.
In the environment Palatinol IC is degraded relatively fast.

Palatinol IC is compatible with PVC.
Palatinol IC is a phthalate ester having the structural formula C6H4(COOCH2CH(CH3)2)2.

Palatinol IC is formed by the esterification of isobutanol and phthalic anhydride.
When it comes to excretion, Palatinol IC is first converted into the hydrolytic monoester monoisobutyl phthalate (MIBP).

The primary excretory route is urine, with biliary excretion being noted in minor amounts.
Palatinol IC has lower density and freezing point than the related compound dibutyl phthalate (DBP).

Palatinol IC can be sold as a pure substance or as a component of mixtures with other phthalate plasticizers or chemicals.
Examples are dioctyl phthalate (DOP), diisononyl-phthalate (DINP), or bis(2-ethylhexyl) phthalate (DEHP).
Palatinol IC is a natural product found in Artemisia baldshuanica, Lythrum salicaria, and other organisms with data available.

Uses of Palatinol IC:
Palatinol IC is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Palatinol IC is used in the following products: coating products, fillers, putties, plasters, modelling clay and polymers.

Other release to the environment of Palatinol IC is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).
Release to the environment of Palatinol IC can occur from industrial use: in the production of articles, formulation of mixtures and of substances in closed systems with minimal release.
Other release to the environment of Palatinol IC is likely to occur from: indoor use, outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

Palatinol IC can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.
Palatinol IC can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), metal (e.g. cutlery, pots, toys, jewellery), rubber (e.g. tyres, shoes, toys), leather (e.g. gloves, shoes, purses, furniture) and wood (e.g. floors, furniture, toys).

Palatinol IC is used in the following products: coating products, fillers, putties, plasters, modelling clay, polymers and adhesives and sealants.
Palatinol IC is used in the following areas: formulation of mixtures and/or re-packaging.

Palatinol IC is used for the manufacture of: plastic products, mineral products (e.g. plasters, cement) and machinery and vehicles.
Release to the environment of Palatinol IC can occur from industrial use: in the production of articles, of substances in closed systems with minimal release and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).

Other release to the environment of Palatinol IC is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).
Palatinol IC is used in the following products: coating products, fillers, putties, plasters, modelling clay and polymers.

Palatinol IC has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Palatinol IC can occur from industrial use: formulation of mixtures and formulation in materials.
Palatinol IC has an industrial use resulting in manufacture of another substance (use of intermediates).

Palatinol IC is used in the following areas: formulation of mixtures and/or re-packaging.
Palatinol IC is used for the manufacture of: chemicals.
Release to the environment of Palatinol IC can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates) and in the production of articles.

Release to the environment of Palatinol IC can occur from industrial use: manufacturing of Palatinol IC.
Palatinol IC is a plasticizer in used in consumer
products as a substitute ingredient to di-n-butyl phthalate (DBP) due to structural similarities.

Therefore, Palatinol IC's presence in products may increase.
Palatinol IC is a plasticizer used in poly-vinyl chloride (PVC) plastic to increase flexibility.

Palatinol IC can be used replacement for dibutyl phthalate due to lower production costs.
Additionally, Palatinol IC can be used in applications such as ink, coatings, lacquers, and adhesives.

Palatinol IC acts as a plasticizer.
Palatinol IC can be used as a replacement for dibutyl phthalate due to lower production costs.

Palatinol IC is used in poly-vinyl chloride (PVC) plastic to increase flexibility.
Palatinol IC is used as plasticizer.

Palatinol IC is used in paints, lacquers, and varnishes.
Palatinol IC is also used in the paper and pulp industry and to make boards, chemicals, polymers, adhesives, softeners, and viscosity adjusters.

Palatinol IC is prepared by esterification process of isobutanol and phthalic anhydride.
Palatinol IC is an odorless plasticizer and has excellent heat and light stability.

Palatinol IC is the lowest cost plasticizer for cellulose nitrate.
Palatinol IC has lower density and freezing point than DBP.

Palatinol IC has similar properties as dibutyl phthalate and can be used as a substitute for it.
Palatinol IC is a colorless transparent oily liquid used as an alternative to DBP (Dibutyl Phthalate).

Palatinol IC is used in nitrocellulose and alkyd resin paints.
Palatinol IC is prepared by esterification process of isobutanol and phthalic anhydride.

Palatinol IC is an odorless plasticizer and has excellent heat and light stability.
Palatinol IC is the lowest cost plasticizer for cellulose nitrate.

Palatinol IC has lower density and freezing point than DBP.
Palatinol IC has similar properties as dibutyl phthalate and can be used as a substitute for it.

Palatinol IC is a plasticizer that is used in nitrocellulose, alkyd resin paints, inks, coatings, lacquers, and adhesives.
Due to lower production costs, Palatinol IC is used as an alternative to DBP (Dibutyl Phthalate).

Palatinol IC is a plasticizer that is used with different polymers such as polyacrylate, poly acetate dispersions, cellulose acetate, nitrocellulose, polyurethane, and polyvinyl butyrate.
Palatinol IC often is used in combination with other phthalates.

Palatinol IC is used most of the time as a substitute for DBP.
Palatinol IC is used in the plasticization of PVC, the production of paints, printing inks, and adhesives.

Some of Palatinol IC uses include: Floorings, Paints, Industrial adhesives, Lacquers, Printing inks, Hydraulic fluids, and Lubricants.
Palatinol IC is used in a variety of products, including food packaging, medical devices, and toys.

Palatinol IC is used as a plasticizer in the manufacture of flexible PVC products, such as wire and cable insulation, vinyl flooring, adhesives, and coatings.
Palatinol IC is also used in the production of lacquers, printing inks, and synthetic leather.

Palatinol IC is a Dialkyl phthalate ester phthalate plasticizer which can be used as a substitute of dibutyl phthalate.
Palatinol IC as well as other phthalates have genotoxic effects and studies shown an increase in its monoester metabolite in human urine over the years.

Palatinol IC is one of the main plasticizers in common use.
Palatinol IC can be used as plasticizer of cellulose resin, vinyl resin, NBR and chlorinated rubber.

Similar to Palatinol IC, it has excellent solubility, dispersibility and adhesion.
Palatinol IC has good compatibility with pigment.

Palatinol IC can be used for coloring film, artificial leather and plastic products.
Palatinol IC can also be used as softener of natural rubber and synthetic rubber to improve the resilience of products.

Palatinol IC can be used as a substitute for DBP.
Palatinol IC is a phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of isobutanol Palatinol IC is considered a specialty plasticizer that is too volatile for use in polyvinyl chloride (PVC).

Palatinol IC is often combined with other phthalates.
Palatinol IC has good heat and light stability and has been used as a plasticizer for nitrocellulose (lowest cost plasticizer for cellulose nitrate), cellulose ether, and polyacrylate and polyacetate dispersions.

Palatinol IC is used in nail polish, cosmetics, lubricants, floor carpets, tapestry, clothing treatments, rubber dentistry settings, as a fuel stabilizer, in leather varnishes and lacquers, as a concrete additive, as an adjusting agent for lead chromate paint pigments, explosive material, lacquer manufacturing, and methyl methacrylate applications.

Palatinol IC is also used in printing inks for paper and packaging.
Because Palatinol IC has similar properties as dibutyl phthalate (DBP), Palatinol ICcan be used as a substitute for DBP.

Palatinol IC is mainly used as nitrocellulose, cellulose acetate, polyvinyl chloride and other plasticizers; General Chemical analysis reagents for gas chromatography stationary liquid.
Palatinol IC is used as solvents, pesticides, plasticizers.

Palatinol IC has similar properties as dibutyl phthalate and can be used as a substitute for it.
Palatinol IC is synthesized by chemical reaction of phthalic acid with iso-butyl alcohol.

Palatinol IC is a plasticizer with coagulating properties which was used with different polymers, e.g. poly acrylate, poly acetate dispersions, cellulose acetate, cellulose nitrate, ethyl cellulose, polyurethane, and polyvinyl butyrate.
In combination with other plasticizers Palatinol IC was applied as gellant in processing of so-called plastisols.

Palatinol IC is present for instance in floorings, adhesives, lacquers, inks, hydraulic fluids and lubricants.
Palatinol IC was used as marker in fuels for tax purposes and also in the production of titanium catalysers.
Palatinol IC can be used as a replacement for dibutyl phthalate due to lower production costs.

Palatinol IC is used in adhesives.
Palatinol IC may be used as a component in formulations of several products including adhesives, paints, coatings and lubricants.

This and other phthalates are used as plasticizers due to their flexibility and durability.
They are found in many industrial and personal products, such as lacquers, nail polish and cosmetics.

Industry uses:
Palatinol IC is used as a plasticizer additive in a range of plastic and rubber materials.
Palatinol IC has low volatility, which makes it ideal for use in products that require long-lasting flexibility, e.g. automotive parts, wire and cable insulation, and flooring.
Palatinol IC is dense and water-insoluble.

Food Industry:
Palatinol IC is used as a plasticizer in food packaging materials, such as polyvinyl chloride (PVC) films and sheets.
Palatinol IC is also used in food contact materials, such as adhesives, coatings, and sealants.
Palatinol IC is used to improve the flexibility, durability, and transparency of these materials.

Production Method of Palatinol IC:
Palatinol IC is manufactured by esterifying phthalic anhydride and isobutanol in the presence of sulfuric acid.
Palatinol IC is synthesized by the esterification process of isobutanol and phthalic anhydride in the presence of sulphuric acid as a catalyst.

Synthesis of Palatinol IC:
Palatinol IC is synthesized by a double nucleophilic acyl substitution reaction between phthalic anhydride and isobutanol, using various acids as a catalyst, such as sulfuric acid, sulfonated graphene, or iron(III) chloride.
Water is a byproduct.
Using sulfuric acid, the yield is 61% yield.

Optimization of Palatinol IC:
Sulfonated graphene is a heterogeneous catalyst that has several advantages over traditional liquid acids like sulfuric acid.
Sulfonated graphene can be easily separated from the reaction mixture by filtration and can be reused multiple times without reduction in activity.

Furthermore, sulfonated graphene is environmentally friendly, as Palatinol ICdoes not produce hazardous waste materials that are typically generated during the use of traditional liquid acid catalysts.
This method has a 95% yield.

Lewis acids, such as FeCl3, can also be used as the catalyst.
The Lewis acid catalysis process can be run at lower temperatures (50-100 °C), and gives a yield of 86%.

Actions Mechanism of Palatinol IC:

PPARγ Pathway:
The effects of Palatinol IC exposure are mainly realized through its activation of peroxisome proliferator-activated receptor gamma (PPARγ).
PPARs are ligand-activated nuclear transcription factors, the family consists of PPARα, PPARβ/δ and PPARγ.
There are two isoforms of PPARγ, PPARγ2 is mainly present on cells in adipose tissue, whereas PPARγ1 is found on multiple cells like those in the gut, brain, blood vessels, and some immune and inflammatory cells.

Transcriptional regulation through PPARs requires the formation of a heterodimer with retinoid X receptor (RXR).
Upon activation by Palatinol IC this PPARγ/RXR heterodimer binds to a DNA sequence called the PPAR response element (PPRE).
Binding of the transcription factor to this response element can result in either up- or down-regulation of genes.

PPARγ is involved in lipid metabolism and storage as well as glucose metabolism through improving insulin sensitivity, so binding of Palatinol IC leads to altered leptin and insulin levels.
Palatinol IC also leads to a down-regulation of proteins involved in steroid production, resulting in higher levels of androgenic hormones.

Cytokine-cytokine receptor pathway
Another type of pathway affected by Palatinol IC exposure is the cytokine-cytokine receptor pathway.
There are two pathways affected: the tumour necrosis factor receptor superfamily (TNFRSF) and the prolactin receptor pathway, both of which affect spermatogenesis.

Environmental Reactions of Palatinol IC:
Palatinol IC can undergo various reactions that may impact the environment

Examples include:

Hydrolysis:
Hydrolyzation of Palatinol IC can be done by enzymes, bacteria, and other microorganisms in the environment to form phthalic acid and isobutyl alcohol.
This can lead to the breakdown and the eventual degradation of Palatinol IC in the soil and water supply

Photodegradation:
Palatinol IC can undergo photodegradation by exposure to the sunlight.
This can lead to the formation of several degradation products, including phthalic acid, isobutyraldehyde, and other aldehydes.

Biodegradation:
Palatinol IC can be degraded by microorganisms in soil and in the water.
This can transform Palatinol IC into other compounds such as phthalic acid and various isobutyl alcohol derivatives.

Sorption:
Palatinol IC can adsorb or sorb onto soil and sediment particles, which can limit Palatinol IC mobility and availability for biological or chemical degradations and reactions.

Oxidation:
Palatinol IC can be oxidized in the presence of ozone or other reactive oxygen species.
The formation of various oxidation products, including aldehydes, ketones, and carboxylic acids can be expected.
These reactions can impact the persistence, bioaccumulation, and toxicity in the environment and may have implications for human and ecosystem health.

Matebolism of Palatinol IC:
Upon entering circulation Palatinol IC is quickly metabolized and excreted through urine, with metabolites reaching peak concentrations 2–4 hours after administration.
The main metabolite of Palatinol IC is mono-isobutyl phthalate (MiBP), which makes up 70% of the excretion products.

MiBP can be oxidized to either 2OH-mono-isobutyl phthalate (2OH-MiBP) or 3OH-mono-isobutyl phthalate (3OH-MiBP), which make up 20% and 1% of the excretion products respectively.
These reactions are likely catalyzed by cytochrome P450 in the liver.

The ratio between MiBP and the oxidized metabolites changes depending on the amount of time that has passed since exposure.
The ratio between MiBP and 2OH-MiBP and that between MiBP and 3OH-MiBP show a similar trend.
With the ratios being high, around 20-30:1, shortly after exposure and dropping gradually as more time passes to rest around 2-5:1.

Therefore, a high ratio of oxidized metabolites to the monoester metabolite suggests that there was recent exposure to Palatinol IC, within a few hours of measuring, while a lower ratio suggests that there has been more time since exposure.
In addition to oxidation, MiBP can also undergo a glucuronidation reaction, resulting in the metabolite MiBP-glucuronide

History of Palatinol IC:
In 1836 French chemist Auguste Laurent oxidized naphthalene with chromic acid and created phthalic anhydride, of which phthalates are derived.
Phthalates, including Palatinol IC, were first introduced in the 1920s to make plastics more flexible, transparent and long-lived.

They increased their popularity in 1931 when polyvinylchloride (PVC) became commercially available.
Due to the increase in human exposure to phthalates, in 1999 the European Union restricted the use of some of them in children’s toys

Storage of Palatinol IC:
Palatinol IC should be stored in a cool, dry, and well-ventilated place.
Palatinol IC should be stored in a Metal drum, stainless steel, aluminum, or polyester-reinforced resin.

Palatinol IC should be kept away from food.
Palatinol IC should be stored in containers, separately from Strong oxidants.

Handling and Storage of Palatinol IC:

Precautions for safe handling:

Advice on safe handling:
Work under hood.

Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with Palatinol IC.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.

Stability and Reactivity of Palatinol IC:

Reactivity:
Palatinol IC reacts with acids to liberate heat along with isobutyl alcohol and phthalic acid.
Palatinol IC may react sufficiently exothermically with strong oxidizing acids to ignite the reaction products.

Heat is also generated by interaction with caustic solutions.
Flammable hydrogen is generated by mixing with alkali metals and hydrides.
Palatinol IC can generate electrostatic charges in handling

Chemical stability:
Palatinol IC is chemically stable under standard ambient conditions (room temperature).

Possibility of hazardous reactions:
No data available

First Aid Measures of Palatinol IC:

General advice:
Show Palatinol IC safety data sheet to the doctor in attendance.

If inhaled:

After inhalation:
Fresh air.
Call in physician.

In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.

In case of eye contact:

After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.

If swallowed:

After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.

Indication of any immediate medical attention and special treatment needed
No data available

Fire Fighting Measures of Palatinol IC:

Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder

Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

Accidental Release Measures of Palatinol IC:

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.

Observe possible material restrictions.
Take up carefully with liquid-absorbent material.

Dispose of properly.
Clean up affected area.

Identifiers of Palatinol IC:
CAS Number: 84-69-5
Molecular Weight: 278.34
Beilstein: 2054802
EC Number: 201-553-2
MDL number: MFCD00026480
Chemical formula: C16H22O4
Molar mass: 278.348 g·mol−1
Appearance: Colorless viscous liquid
Density: 1.038 g/cm3
Melting point: −37 °C (−35 °F; 236 K)
Boiling point: 320 °C (608 °F; 593 K)
Solubility in water: 1 mg/L at 20 °C
log P: 4.11
Vapor pressure: 0.01 Pa at 20 °C
Flash point: 185 °C (365 °F; 458 K) c.c.
Autoignition temperature: 400 °C (752 °F; 673 K)

Melting Point: -37 °C
Flammability: Combustible
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 296.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.002000 mmHg @ 25.00 °C. (est)
Flash Point: 309.00 °F. TCC (153.90 °C.) (est)
logP (o/w): 4.110
Soluble in: water, 6.2 mg/L @ 24C (exp)
CAS: 84-74-2
EINECS: 201-557-4
InChIKey: DOIRQSBPFJWKBE-UHFFFAOYSA-N
Molecular Formula: C16H22O4
Molar Mass: 278.34

Storage Condition: 2-8°C
Sensitive: Easily absorbing moisture
Explosive Limit: 0.47%, 236°F
Refractive Index: n20/D 1.492(lit.)
MDL: MFCD00009441
Chemical Formula: C16H22O4
Average Molecular Mass: 278.344 g/mol
Monoisotopic Mass: 278.152 g/mol
CAS Registry Number: 84-69-5
IUPAC Name: 1,2-bis(2-methylpropyl) benzene-1,2-dicarboxylate
Traditional Name: Palatinol IC
SMILES: CC(C)COC(=O)C1=CC=CC=C1C(=O)OCC(C)C
InChI Identifier: InChI=1S/C16H22O4/c1-11(2)9-19-15(17)13-7-5-6-8-14(13)16(18)20-10-12(3)4/h5-8,11-12H,9-10H2,1-4H3
InChI Key: InChIKey=MGWAVDBGNNKXQV-UHFFFAOYSA-N

Properties of Palatinol IC:
Molecular Weight: 278.34 g/mol
XLogP3: 4.1
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 8
Exact Mass: 278.15180918 g/mol
Monoisotopic Mass: 278.15180918 g/mol
Topological Polar Surface Area: 52.6Ų
Heavy Atom Count: 20
Complexity: 290
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Physical state: liquid
Color: colorless
Odor: weak
Melting point/freezing point:
Melting point: -64 °C
Initial boiling point and boiling range: 327 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 3,2 %(V)
Lower explosion limit: 0,8 %(V)
Flash point: 109 °C - closed cup
Autoignition temperature: 423 °C at 1.013 hPa
Decomposition temperature: No data available
pH: neutral

Viscosity:
Viscosity, kinematic: 13,96 mm2/s at 40 °C
Viscosity, dynamic: No data available
Water solubility 0,02 g/l at 20 °C - slightly soluble
Partition coefficient: n-octanol/water:
log Pow: 4,11 at 20 °C
Vapor pressure: 0,11 hPa at 100 °C
Density: 1,039 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

Melting Point: -64 °C
Boiling Point: 295.3±8.0 °C at 760 mmHg
Flash Point: 153.9±7.9 °C
Molecular Formula: C16H22O4
Molecular Weight: 278.344
Density: 1.0±0.1 g/cm3
Molecular Formula: C16H22O4
IUPAC name: bis(2-methylpropyl) benzene-1,2-dicarboxylate
Cas Number: 84-69-5
Molecular weight: 278.34 g/mol
Density: 1.039 g/mL
Boiling Point: 320 °C
Flashpoint: 185 °C

Density: 1.043 g/mL at 25 °C (lit.)
Melting Point: -35 °C (lit.)
Boling Point: 340 °C (lit.)
Flash Point: 340°F
Water Solubility: Slightly soluble. 0.0013 g/100 mL
Solubility: Soluble in water (0.4 mg/ml at 20 °C), ethanol.
Very soluble in ether, acetone, and B
Vapor Presure: 1 mm Hg ( 147 °C)
Vapor Density: 9.6 (vs air)
Appearance: Colorless liquid
Specific Gravity: 1.049 (20/20℃)
Color: APHA: ≤10
Exposure Limit NIOSH REL: TWA 5 mg/m3, IDLH 4,000 mg/m3;
OSHA PEL: TWA5 mg/m3; ACGIH TLV: TWA 5 mg/m3.
Merck: 14,3035
BRN: 1914064

Compound Type of Palatinol IC:
Aromatic Hydrocarbon
Cosmetic Toxin
Ester
Ether
Household Toxin
Industrial/Workplace Toxin
Metabolite
Organic Compound
Phthalate
Plasticizer
Synthetic Compound

Alternative Parents of Palatinol IC:
Benzoyl derivatives
Dicarboxylic acids and derivatives
Carboxylic acid esters
Organooxygen compounds
Organic oxides
Hydrocarbon derivatives

Substituents of Palatinol IC:
Benzoate ester
Benzoyl
Dicarboxylic acid or derivatives
Carboxylic acid ester
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Aromatic homomonocyclic compound
 

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