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Paraformaldehyde (PFA) is the smallest polyoxymethylene, the polymerization product of formaldehyde with a typical degree of polymerization of 8–100 units. P
Paraformaldehyde commonly has a slight odor of formaldehyde due to decomposition.
Paraformaldehyde is a poly-acetal.
CAS NUMBER: 30525-89-4
EC NUMBER: 608-494-5
MOLECULAR FORMULA: HO(CH2 O)xH
MOLECULAR WEIGHT: Not available because this is not a discrete structure.
IUPAC NAME: -
Paraformaldehyde is the informal name of polyoxymethylene, a polymer of formaldehyde
Paraformaldehyde appears as a white solid with a light pungent odor.
Paraformaldehyde is a linear polymer of formaldehyde of formula HO(CH2-O)xH where x averages about 30.
Paraformaldehyde is soluble in water when x is less than 12; higher polymers are not immediately soluble.
Slow dissolution in water proceeds by means of hydrolysis to give fragments of lower x.
Paraformaldehyde is flammable, although may take some effort to ignite.
Paraformaldehyde's flash point 158 °F.
Paraformaldehyde is used in fungicides, bactericides, and in the manufacture of adhesives.
Paraformaldehyde is an aldehyde.
Paraformaldehyde is the simplest aldehyde in the aldehyde series.
At room temperature and pressure, Paraformaldehyde is a gaseous compound.
Paraformaldehyde is a white solid with a light pungent odor.
Paraformaldehyde is a polymer formed from formaldehyde.
Typically, Paraformaldehyde is composed of 8-100 formaldehyde units.
Paraformaldehyde has chemical and physical properties that are different from formaldehyde.
The main difference between Paraformaldehyde and formaldehyde is that paraformaldehyde is in the solid phase at room temperature and pressure whereas formaldehyde is a gas.
Synthesis:
Paraformaldehyde forms slowly in aqueous formaldehyde solutions as a white precipitate, especially if stored in the cold.
Formalin actually contains very little monomeric formaldehyde; most of it forms short chains of polyformaldehyde.
A small amount of methanol is often added as a stabilizer to limit the extent of polymerization.
Reactions:
Paraformaldehyde can be depolymerized to formaldehyde gas by dry heating and to formaldehyde solution by water in the presence of a base, an acid or heat.
The high purity formaldehyde solutions obtained in this way are used as a fixative for microscopy and histology.
The resulting formaldehyde gas from dry heating Paraformaldehyde is flammable.
APPLICATIONS:
*Urea-Formaldehyde Resin
*Phenolic Resin
*Melamine Resin
*Fumigation
*Reagent for organic reactions
*Coating
*Pesticide
*Disinfectant
*Pharmaceuticals
Uses:
Once Paraformaldehyde is depolymerized, the resulting formaldehyde may be used as a fumigant, disinfectant, fungicide, and fixative.
Longer chain-length (high molecular weight) polyoxymethylenes are used as a thermoplastic and are known as polyoxymethylene plastic (POM, Delrin).
Paraformaldehyde was used in the past in the discredited Sargenti method of root canal treatment.
Paraformaldehyde is not a fixative; it must be depolymerized to formaldehyde in solution.
In cell culture, a typical formaldehyde fixing procedure would involve using a 4% formaldehyde solution in phosphate buffered saline (PBS) on ice for 10 minutes.
Paraformaldehyde is also used to crosslink proteins to DNA, as used in ChIP (chromatin immunoprecipitation) which is a technique to determine which part of DNA certain proteins are binding to.
Paraformaldehyde can be used as a substitute of aqueous formaldehyde to produce the resinous binding material, which is commonly used together with melamine, phenol or other reactive agents in the manufacturing of particle board, medium density fiberboard and plywood.
Paraformaldehyde is a white powder (CH2O)x that consists of a polymer of formaldehyde
Paraformaldehyde is used especially as a fungicide.
Paraformaldehyde is a polymer of formaldehyde.
Paraformaldehyde itself is not a fixing agent, and needs to be broken down into its basic building block, formaldehyde.
This can be done by heating or basic conditions until it becomes solubilized.
Paraformaldehyde is the solid form of liquid formaldehyde, formed by the polymerization of formaldehyde with a typical degree of polymerization of 8-100 units.
Since Paraformaldehyde is basically a condensed form of formaldehyde, it possesses the same characteristics but with a wider range of applications.
Use of Paraformaldehyde in resin production offers many advantages as compared to aqueous formaldehyde:
-Higher productivity from existing equipment and less water to be removed from the resin product.
-Paraformaldehyde takes the form of prilled, is stable and very easy to store.
Paraformaldehyde storage is less expensive than the storage of formaldehyde solution, which requires expensive tanks and which may need stabilization or be kept warm.
-Use of Paraformaldehyde is convenient and safe.
Paraformaldehyde avoids pollution arising from the disposal of the distillate obtained in the thermosetting resin production which is contaminated with organic matter.
-Paraformaldehyde does not need to be dissolved in water in order to take part in a chemical reaction.
-Paraformaldehyde eliminates the risk of transporting liquid formalin, which is notoriously dangerous.
Perfect for small uses straight from the bag.
Paraformaldehyde is used as a disinfectant, fungicide, fixation reagent and in the preparation of formaldehyde.
In fluorescence studies, Paraformaldehyde is used as as a formalin fixative to fix cells and tissues.
To use the chemical as a fixative, it must be converted to the monomer formaldehyde by heating as formaldehyde is the active chemical in fixation.
PHYSICAL PROPERTIES:
-Molecular Formula: OH-(CH2O)n-H where n=8 to 100 units
-Physical Description: White solid with a pungent odor
-Color: White
-Form: Solid
-Odor: Light pungent odor
-Melting Point: 164 °C
-Flash Point: 71 °C
-Solubility: Slowly soluble in cold , more readily soluble in hot water
-Density: 1.46
-Reactivity: 2 – 8 min
-Mean Particle Size: 250 – 350 µm
Paraformaldehyde is used as a disinfectant and hardening agent
Paraformaldehyde is used as a waterproofing agent.
Paraformaldehyde is also used to prepare adhesives, resins and in dentistry as an antiseptic.
Paraformaldehyde is also employed as a thermoplastic.
In addition, Paraformaldehyde is used in the preparation of formalin fixatives for tissues or cells, particularly when the samples are subjected to florescence studies.
CHEMICAL PROPERTIES:
-Vapor Density: 1.03
-Vapor Pressure: 10.5 mmHg
-Autoignition Temperature: 300 °C
-Decomposition: 120-180 °C
-Heat of Combustion: -3,712 cal/g
-pKa: 15.50
-Heat of solution: -83.5 cal/g
-Chemical Classes: Other Classes -> Aldehydes
Application Areas:
*Agricultural chemicals
*paint industry
*pharmaceutical & chemical industry
*organic chemical syntheses
*fertilizers
*pharmaceuticals
*printing & photography
*fluorescent lights
*consumer goods
*cleaning products
*personal care products
*intermediate additives and compounds.
Other Applications:
One of the most important uses of our paraformaldehyde solutions is as formalin fixatives for tissues or cells.
Paraformaldehyde is also used as a source of formaldehyde groups in the production of many thermosetting resins, together with phenol, urea, melamine, resorcinol and other similar reagents.
These resins are used as moulding powders
Paraformaldehyde is used in the wood industry as glues for chipboard, plywood and furniture
Paraformaldehyde is used as bonding resins for brakes, abrasives and foundry dyes
Paraformaldehyde can be used as finishing resins for paper and textiles
Paraformaldehyde is also used as driers and glossing agents for paints
Paraformaldehyde is used as insulating varnishes for electrical parts.
Some additional typical formulations for the production of such resins starting from Paraformaldehyde include dichloroethyl formal, methyl phenol, disinfectants, insecticides, pharmaceuticals such as vitamin A, embalming preparations, dyestuff and special plasticizers.
Paraformaldehyde is soluble in hot water, and many organic solvents.
Paraformaldehyde is insoluble in water, ether, and alcohol.
Paraformaldehyde is a white, solid polymer of formaldehyde
Paraformaldehyde has a pungent, characteristic formaldehyde odor.
Paraformaldehyde is made up of connected formaldehyde molecules.
Paraformaldehyde is slightly soluble in alcohols and insoluble in ethers, hydrocarbons, and carbon tetrachloride.
Paraformaldehyde is relative insoluble in cold water, but soluble in hot water with depolymerization.
The solubility and rate of solution of Paraformaldehyde in water are greatly influenced by pH and temperature.
Both acidic and alkaline pHs and higher temperatures accelerate the rate of solution.
Once dissolved, the Paraformaldehyde solution behaves like the methanol-free formaldehyde solution of the same concentration.
Paraformaldehyde is composed of varying molecular weight polymers of polyoxymethylene glycols.
Paraformaldehyde is generally prepared as 91 or 95% formaldehyde by weight with the remainder being free and combined water.
The combined water is the terminating agent for the Paraformaldehyde chains.
Paraformaldehyde reacts chemically as formaldehyde at a rate determined by its rate of depolymerization under the conditions of use.
The rate of depolymerization and thus perceived reactivity decreases with increasing molecular weight of the polymer chains.
Paraformaldehyde is widely used by resin manufacturers seeking low water content, or more favorable control of reaction rates when compared to aqueous formaldehyde solutions.
With less dehydration required, Paraformaldehyde resins are made in less time.
Better yields result from the complete or partial elimination of dehydration because fewer reactants are lost in the distillate.
Utility costs are reduced because paraformaldehyde requires less steam, cooling water and power for water removal.
The capability of charging more reactants to the process equipment (in the volume otherwise occupied by water and extra azeotroping agent) increases reactor capacity, and reduces capital required for equipment versus the equipment costs and capacity when using aqueous formaldehyde.
Finally, and of increasing importance, less wastewater is produced. Paraformaldehyde provides a source of formaldehyde for the synthesis of phenol-, urea-, furfural alcohol-, resorcinol- and melamine- formaldehyde resins.
These products find extensive usage in industrial coatings, wood products, textiles, and foundry resins.
Oil well drilling chemicals, lubricating oil additives, adhesive resins, and electrical component molding materials also use Paraformaldehyde.
Miscellaneous end uses include photographic and graphic arts chemicals, pigments, rubber antioxidants, fluorescent tube and ink chemicals, pharmaceuticals, slow release fertilizers and others.
Paraformaldehyde is weighed out and dissolved in solution for use in cell and tissue fixation.
Paraformaldehyde is widely used fixative for IHC and fluorescent protein samples
Paraformaldehyde (chemical name is polyoxymethylene) is a powder of polymerized formaldehyde that by itself cannot fix tissues
Paraformaldehyde is the smallest solid form of liquid formaldehyde, formed by the polymerization of formaldehyde with a typical degree of polymerization of 8-100 units.
As Paraformaldehyde is basically a condensed form of formaldehyde, it possesses the common characteristics with a wide range of applications.
Paraformaldehyde is used in the manufacturing of various agricultural chemicals such as herbicides, pesticides, bactericides, fertilizers, etc
Paraformaldehyde is a polymer of formaldehyde
Paraformaldehyde appears as a white solid with a light pungent odor.
Paraformaldehyde's formula is HO(CH2-O)xH where x averages about 30.
Paraformaldehyde is soluble in water
Paraformaldehyde is flammable
Paraformaldehyde's flash point 158 °F.
Paraformaldehyde is used in the manufacture of adhesives.
Paraformaldehyde is an aldehyde.
Paraformaldehyde is the simplest aldehyde in the aldehyde series.
Paraformaldehyde is a white solid with a light pungent odor.
Paraformaldehyde has chemical and physical properties that are different from formaldehyde.
SYNONYMS:
Paraformaldehyde
30525-89-4
Formagene
Aldacide
Flo-Mor
Polyoxymethylene glycol
Paraformic aldehyde
Polymerised formaldehyde
Y19UC83H8E
(CH2O)n
Oilstop, Halowax
Paraformaldehydum
608-494-5
HSDB 4070
Hyperband
PARAFORMALDEHYDE
Paraforsn
UNII-Y19UC83H8E
paraform
triformol
paraformaldehyde
para formaldehyde
para form aldehyde
peraformaldehyde
pera form aldehyde
pera formaldehyde
paraformaldehit
para formaldehit
para form aldehi
Paraformaldehyde
Para Formaldehyde
Para Form Aldehyde
Peraformaldehyde
Pera Form Aldehyde
Pera Formaldehyde
Paraformaldehit
Para formaldehit
Para Form Aldehit
PARAFORMALDEHIT
PARA FORMALDEHYDE
PARA FORM ALDEHYDE
PARAFORMALDEHYDE
PERA FORM ALDEHYDE
PERA FORMALDEHYDE
PARAFORMALDEHYDE
PARA FORMALDEHIT
PARA FORM ALDEHIT
formalin; methanal
formol; methylene oxide
paraformaldehyde
oxomethane
paraform
formic aldehyde;
oxymethylene
methyl aldehyde
Polyoxymethylene
Polyoxymethylene
metaformaldehyde
paraform
formagene
paraffinize
paraffinoid
paraffinoma
parafoil
parafollicular cell
paraformaldehyde
paraganglioma
paraganglion
paragenesis
parageusia
paraglide
paraflutizide
parafoil
parafoil
parafollicula
paraformaldehyde
paraformer
paraformers
parafoveal
parafransoletite
paraganglia
formaldehyde
formalin
methanal
formol
Paraformaldehyde
Formaldehyde
Formalin
Formol
Methanal
Oxomethane
formaldehyde
formalin
methanal
formol
Paraformaldehyde
50-00-0
Methylene oxide
Oxomethane
Paraform
Formic aldehyde
Oxymethylene
Methyl aldehyde
Fannoform
Formalith
Formaldehyde solution
Methaldehyde
Superlysoform
Formalina
Lysoform
Morbicid
Karsan
Formaldehyd
Formaline
Oxomethylene
Polyoxymethylene
Aldehyde formique
FYDE
Formaldehyde, gas
Formalin 40
Aldeide formica
30525-89-4
Oplossingen
Dormol
Polyformaldehyde
Formalin-loesungen
Paraformic aldehyde
