PRODUCTS

PCL-SOLID

PCL-Solid is a mixture of long-chain fatty acid esters used as an emollient with well-developed consistency giving properties.
PCL-Solid is a colorless wax that melts at skin temperature, has neutral odor, gives emulsions a pleasant consistency and increases their stability.
PCL-Solid creates a soft, pleasant, smooth skin feel, has high levels of refatting potential, also demonstrates strong water repellent properties and forms a hydrophobic film that protects the skin from drying out.

CAS Number: 66009-41-4
Molecular Formula: C25H50O2
Molecular Weight: 382.66
EINECS Number: 266-065-4

Synonyms: CETEARYL NONANOATE, 878027-13-5, NONANOIC ACID, C16-18-ALKYL ESTERS, SYMMOLLIENT S 181598, F6ZWV2F361

PCL-Solid refers to a type of solid formulation of Polycaprolactone (PCL).
PCL-Solid is a biodegradable polyester with a variety of uses in industry and research.
PCL-Solid is a reliable emollient with valuable caring properties.

It melts slightly above skin temperature.
PCL-Solid gives emulsions a pleasant consistency and helps to increase their stability.
This ingredient creates a soft, pleasant and smooth skin feel.

PCL-Solid enhances the caring characteristic of formulations.
PCL-Solid is an emollient.
This bioinspired ester oil helps to protect skin.

It makes the skin soft, smooth and supple.
PCL-Solid helps the skin to maintain its natural equilibrium.
This ingredient spreads quickly on skin and has a strong film-forming effect without being occlusive.

Thus, it does not inhibit the natural skin respiration.
PCL-Solid does not leave a sticky or greasy skin feeling.
It maintains the natural moisture content of the skin.

PCL-Solid mimics the composition of natural preen-gland oil but is of course not animal-derived.
PCL-Solid offers low variation of viscosity with temperature.
PCL-Solid is particularly suitable for W/O emulsions.

Solid polymer electrolytes (SPEs) have attracted considerable attention for high energy solid-state lithium metal batteries (LMBs).
In this work, potentially ecofriendly, solid-state poly(ε-caprolactone) (PCL)-based star polymer electrolytes with cross-linked structures (xBt-PCL) are introduced that robustly cycle against LiNi0.6Mn0.2Co0.2O2 (NMC622) composite cathodes, affording long-term stability even at higher current densities.

PCL-Solid used in bone tissue regeneration should have highly porous micro-architecture.
In addition, they should have high mechanical properties and be biodegradable and biocompatible.
In this respect, the solid freeform fabricated PCL–β-TCP scaffold has been widely applied in bone tissue regeneration.

PCL-Solid is a synthetic, semi-crystalline, biodegradable polyester with a melting point of about 60 °C and a glass transition temperature of about −60 °C.
The most common use of polycaprolactone is in the production of speciality polyurethanes.
PCL-Solid impart good resistance to water, oil, solvent and chlorine to the polyurethane produced.

This polymer is often used as an additive for resins to improve their processing characteristics and their end use properties (e.g., impact resistance).
Being compatible with a range of other materials, PCL-Solid can be mixed with starch to lower its cost and increase biodegradability or it can be added as a polymeric plasticizer to polyvinyl chloride (PVC).

PCL-Solid is also used for splinting, modeling, and as a feedstock for prototyping systems such as fused filament fabrication 3D printers.
PCL-Solid also has many applications in the hobbyist market where it is known as Re-Form, Polydoh, Plastimake, NiftyFix, Protoplastic, InstaMorph, Polymorph, Shapelock, ReMoldables, Plastdude, TechTack, or Friendly Plastic.
PCL-Solid has physical properties of a very tough, nylon-like plastic that softens to a putty-like consistency at only 60 °C, easily achieved by immersing in hot water.

PCL-Solid's specific heat and conductivity are low enough that it is not hard to handle by hand at this temperature.
This makes it ideal for small-scale modeling, part fabrication, repair of plastic objects, and rapid prototyping where heat resistance is not needed.
Though softened PCL readily sticks to many other plastics when at higher temperature, if the surface is cooled, the stickiness can be minimized while still leaving the mass pliable.

PCL-Solid is biodegradable and can be broken down by microbial activity.
PCL-Solid is used in applications where biodegradability is desired, such as in medical devices and packaging.
PCL-Solid is a thermoplastic polymer, meaning it becomes moldable above a specific temperature and solidifies upon cooling.

PCL-Solid is used in 3D printing, film coating, and as a carrier in drug delivery systems.
It has a low melting point (approximately 60°C), which makes it easy to process.
It also has good flexibility and toughness.

Suitable for applications requiring a combination of flexibility and durability.
PCL-Solid soluble in organic solvents like chloroform, dichloromethane, and toluene.
PCL-Solid is used in solvent-based formulations and for creating coatings and films.

PCL-Solid is used in the manufacture of biodegradable implants and prosthetics.
Utilized as a matrix for controlled-release drug delivery systems.
Employed as a filament in 3D printing due to its low melting point and ease of processing.

PCL-Solid is used in rapid prototyping and custom manufacturing.
Applied in the creation of environmentally friendly packaging materials.
PCL-Solid is used for film coatings on tablets and other drug delivery systems.

Incorporated into fibers for textiles that require specific properties like biodegradability or flexibility.
Avoid inhaling dust or vapors.
PCL-Solid use in a well-ventilated area.

Generally safe but may cause irritation in some individuals. Wear appropriate protective clothing.
Rinse with water if contact occurs.
Follow local regulations for the disposal of polymer materials to minimize environmental impact.

LogP: 11.485 (est)
FDA UNII: 2M4UGL1NCN

PCL-Solid is degraded by hydrolysis of its ester linkages in physiological conditions (such as in the human body) and has therefore received a great deal of attention for use as an implantable biomaterial.
In particular PCL-Solid is especially interesting for the preparation of long term implantable devices, owing to its degradation which is even slower than that of polylactide.

PCL-Solid has been widely used in long-term implants and controlled drug release applications.
However, when PCL-Solid comes to tissue engineering, PCL suffers from some shortcomings such as slow degradation rate, poor mechanical properties, and low cell adhesion.
The incorporation of calcium phosphate-based ceramics and bioactive glasses into PCL-Solid has yielded a class of hybrid biomaterials with remarkably improved mechanical properties, controllable degradation rates, and enhanced bioactivity that are suitable for bone tissue engineering.

PCL-Solid has been approved by the Food and Drug Administration (FDA) in specific applications used in the human body as (for example) a drug delivery device, suture, or adhesion barrier.
PCL-Solid is used in the rapidly growing field of human esthetics following the recent introduction of a PCL-based microsphere dermal filler belonging to the collagen stimulator class (Ellansé).
Through the stimulation of collagen production, PCL-Solid products are able to correct facial ageing signs such as volume loss and contour laxity, providing an immediate and long-lasting natural effect.

PCL-Solid is being investigated as a scaffold for tissue repair by tissue engineering, GBR membrane.
It has been used as the hydrophobic block of amphiphilic synthetic block copolymers used to form the vesicle membrane of polymersomes.
A variety of drugs have been encapsulated within PCL-Solid beads for controlled release and targeted drug delivery.

In dentistry (as the composite named Resilon), PCL-Solid is used as a component of "night guards" (dental splints) and in root canal filling.
PCL-Solid performs like gutta-percha, has similar handling properties, and for re-treatment purposes may be softened with heat, or dissolved with solvents like chloroform.
Similar to gutta-percha, there are master cones in all ISO sizes and accessory cones in different sizes and taper available.

The major difference between the polycaprolactone-based root canal filling material (Resilon and Real Seal) and gutta-percha is that the PCL-based material is biodegradable, whereas gutta-percha is not.
There is a lack of consensus in the expert dental community as to whether a biodegradable root canal filling material, such as Resilon or Real Seal is desirable.
PCL-Solid has a relatively high degree of crystallinity compared to other biodegradable polymers.

The melting point of PCL-Solid is around 60°C, which is lower than many other polymers, making it suitable for processes requiring lower temperatures.
PCL-Solid exhibits moderate tensile strength, which can be improved through blending with other polymers or by using various processing techniques.
It has good elongation at break, allowing it to stretch without breaking, which is useful for flexible applications.

PCL-Solid degrades relatively slowly in the environment, which can be advantageous or disadvantageous depending on the application.
Its degradation rate can be accelerated by environmental factors such as moisture, temperature, and microbial activity.
PCL-Solid can be blended with other polymers to modify its properties, such as increasing its mechanical strength or altering its degradation rate.

Various additives can be incorporated into PCL-Solid to enhance its properties or add functionalities, such as colorants, plasticizers, or stabilizers.
PCL-Solid is used in sutures and implants due to its biocompatibility and ability to degrade gradually in the body.
It is employed as a scaffold material in tissue engineering to support cell growth and tissue regeneration.

PCL-Solid's low melting point makes it ideal for prototyping and creating complex structures in 3D printing.
It is used to manufacture custom parts and tools where high precision and customization are required.
PCL-Solid can be used in food packaging to provide a biodegradable alternative to conventional plastic.

PCL-Solid is used as a protective coating for various products to enhance their shelf life and safety.
PCL-Solid is used to create drug delivery systems that release medication in a controlled manner over time.
Incorporated into various medical devices where controlled degradation and biocompatibility are essential.

PCL-Solid fibers can be used in textiles to create fabrics with unique properties, such as enhanced durability or biodegradability.
PCL-Solid in a dry environment to prevent moisture absorption, which can affect its processing and properties.
Keep PCL-Solid at appropriate temperatures to prevent degradation or changes in its physical properties.

Wear gloves and safety goggles when handling PCL-Solid, especially in powdered form or during processing to avoid skin or eye irritation.
PCL-Solid use in well-ventilated areas to avoid inhaling dust or vapors.

Explore recycling options for PCL-Solid waste to minimize environmental impact.
Some forms of PCL can be recycled or reprocessed.
Follow local regulations for the disposal of PCL-Solid materials to ensure environmentally responsible practices.

Uses Of PCL-Solid:
PCL-Solid is used in the creation of biodegradable implants and prosthetics due to its biocompatibility and gradual degradation in the body.
Employed in the manufacture of absorbable sutures for surgical procedures.
Utilized in controlled-release drug delivery systems, where it acts as a matrix for the gradual release of medications.

Serves as a scaffold material in tissue engineering to support cell growth and tissue regeneration.
PCL-Solid is used as a filament in 3D printing due to its low melting point, which facilitates easy processing and molding.
Ideal for creating custom parts and prototypes, especially where high precision and flexibility are needed.

Employed in the development of environmentally friendly, biodegradable packaging solutions for various products.
PCL-Solid is used as a coating material to enhance the shelf life and safety of packaged goods.
Incorporated into fibers for textiles, offering properties like biodegradability, flexibility, and durability.

Applied in the production of controlled-release pharmaceutical formulations, where PCL-Solid helps to regulate the release rate of active ingredients.
PCL-Solid is used as a coating material for various medical devices to improve their performance and biocompatibility.
PCL-Solid can be used in adhesives and sealants, where its thermoplastic nature allows for easy processing and application.

PCL-Solid is used in industrial coatings for its protective properties and ease of application.
Utilized in applications aimed at controlling soil erosion, where its biodegradability helps in environmental restoration.
PCL-Solid used in cosmetic formulations as a film-forming agent in products such as nail polishes and certain types of facial masks.

Employed in various modeling and crafting applications due to its ease of shaping and molding.
PCL-Solid is used in orthopedic applications to create devices that support bone healing and tissue regeneration.
Applied in formulations and devices designed for bone tissue engineering, leveraging its biocompatibility and gradual degradation.

PCL-Solid is used in environmental applications such as pollution control and waste management.
Its biodegradable nature makes it suitable for creating materials that aid in the removal of pollutants.
Incorporated into packaging materials for food items to provide a biodegradable alternative to conventional plastics, helping reduce environmental impact.

PCL-Solid is used in automotive interior components where lightweight, flexible, and durable materials are required.
Employed in the production of lightweight and durable parts for aerospace applications, benefiting from its processing characteristics and performance properties.
Utilized in the encapsulation of electronic components, providing protection and insulation due to its thermal stability and low melting point.

PCL-Solid applied in the manufacturing of certain sporting goods where flexibility and impact resistance are desired.
PCL-Solid is used in art and design to create detailed and custom molds, leveraging its ease of processing and molding capabilities.
PCL-Solid employed in research and development settings to explore new applications and improve existing technologies due to its versatile nature.

Incorporated into certain construction materials for specialized applications, such as lightweight fillers or coatings.
PCL-Solid investigated for use in energy storage systems where its properties can be leveraged for new technologies.

Safety Profile Of PCL-Solid:
When processed in powdered form, PCL-Solid can generate dust, which may pose respiratory hazards if inhaled.
Ensure proper ventilation or use of dust control measures when handling powdered PCL-Solid.
PCL-Solid has a low melting point (~60°C). During processing, high temperatures can release fumes, so it's important to manage temperatures to prevent overheating.

Inhalation of PCL-Solid dust or fumes can cause respiratory irritation.
Use respiratory protection and ensure proper ventilation in processing areas.
Prolonged or repeated skin contact with PCL might cause irritation in some individuals.

Use appropriate protective clothing and gloves to minimize direct contact.
Dust or particles from PCL-Solid may cause irritation if they come into contact with the eyes.
Safety goggles should be worn when handling PCL-Solid in powdered or granulated form.

While PCL-Solid is biodegradable, its degradation is slow compared to some other bioplastics.
Proper disposal and management are necessary to minimize environmental impact.
Large quantities of PCL-Solid, if not properly managed, could potentially contribute to water pollution.

Proper disposal and recycling practices should be followed to minimize environmental impact.
Store PCL-Solid in a cool, dry place to prevent it from degrading or changing physical properties.
Avoid exposure to excessive heat.

PCL-Solid can absorb moisture, which may affect its processing and properties.
Store in a moisture-free environment and use moisture-proof packaging if necessary.