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PEG 120 METHYL GLUCOSE DIOLEATE

A surfactant and emulsifier 
PEG 120 Methyl Glucose Dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid. It is used in beauty products and cosmetics as a surfactant and emulsifier. It is used as a thickener in hair and skin care products.

PEG 120 METHYL GLUCOSE DIOLEATE

CAS No. : 86893-19-8
EC No. : 617-932-4

Synonyms:
Diethoxylated methyl glucopyranoside 2,6-dioleate; PEG-120 methyl glucose trioleate; Glucamate DOE-120; Diethoxylated methyl glucopyranoside 2,6-dioleate; Ethoxylated methyl glucoside dioleate; Macrogol 120 methylglucosedioleate; METHYL GLUCOSE DOLEATE; peg-120 metil glukoz dioleat; peg120metilglukozdioleat; PEG-120 METİL GLUKOZ DİOLEAT; PEG12METİLGLUKOZDİOLEAT; methil glukoze dioleat; Peg 120 Methyl Glucose Dioleate; Peg-120 Methyl Glucose Dioleate; PEG-120 methylglucosedioleate; PEG 120 METİL GLUKOZ DİOLEAT; PEG 120 METİL GLİKOZ DİOLAT; peg120 metilglukozdiolat; PEG-120 METHYLGLUCOSEDIOLEATE; PEG120METHYLGLUCOSEDIOLEATE; PEG120 METHYL GLUCOSE DIOLEATE; PEG120 methyl glucose dioleate; PEG120methylglucosedioleate; Macrogol 120 methyl glucose dioleate; methyl glucose dioleate; methyl gluceth-10; PEG-120 methyl glucose trioleate; Glucamate DOE-120; Diethoxylated methyl glucopyranoside 2,6-dioleate; Ethoxylated methyl glucoside dioleate; Macrogol 120 methylglucosedioleate; METHYL GLUCOSE DOLEATE; peg-120 metil glukoz dioleat; peg120metilglukozdioleat; PEG-120 METİL GLUKOZ DİOLEAT; PEG12METİLGLUKOZDİOLEAT; methil glukoze dioleat; 120peg methyl glucose dioleate; metilene glukoze dioleate; peg-120; PEG 120; PEG120; peg120; P E G 120; Macrogol 120 methil glucose dioleate; methyl glucose dioleat; methyl gluceth; PEG120 methyl glucose trioleate; GlucamateDOE120; Diethoxylatedmethylglucopyranoside 26-dioleate; Ethoxylatedmethyl glucoside dioleate; Macrogol120 methylglucosedioleate; METHYL GLUCOSE DOLEATE; Peg 120 Methyl Glucose Dioleate; Macrogol 120 methyl glucose dioleate; POE (120) methyl glucose dioleate; 86893-19-8; Peg 120 Methyl Glucose Dioleate; Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with methyl D-glucopyranoside 2,6-di-(9Z)-9-octadecenoate (2:1); Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with methyl D-glucopyranoside 2,6-di-9-octadecenoate (2:1), (Z,Z)-; Diethoxylated methyl glucopyranoside 2,6-dioleate; UNII-YM0K64F20V; Ethoxylated methyl glucoside dioleate; Antil 120 Plus; Unitol 120 Plus; Peg 120 Methyl Glucose Dioleate; Poly(oxy-1,2-ethanediyl),a-hydro-w-hydroxy-, ether with methylD-glucopyranoside 2,6-di-9-octadecenoate (2:1), (Z,Z)- ; Peg 120 Methyl Glucose Dioleate; Glucamate DOE-120; Antil 120Plus; PEG 120 Methyl Glucose Dioleate; Diethoxylated methyl glucopyranoside 2,6-dioleate; Glucamate DOE 120; ose dioleate; Ethoxylated methyl glucoside dioleate; Diethoxylated methyl glucopyranoside 2,6-dioleate; Glucamate DOE 120, Antil 120 Plus,cas:86893-19-8; Diethoxylated methyl glucopyranoside 2,6-dioleate; UNII-YM0K64F20V; Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with methyl D-glucopyranoside 2,6-di-(9Z)-9-octadecenoate (2:1); Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with methyl D-glucopyranoside 2,6-di-9-octadecenoate (2:1), (Z,Z)-; Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl d-glucopyranoside 2,6-bis[(Z)-9-octadecenoate] (2:1) (120 mol EO average molar ratio); (C2-H4-O)mult-(C2-H4-O)mult-C21-H42-O4; 51158-08-8; Cutina E 24PF; Ethoxylated glyceryl monostearate; Glycerin monostearate polyethylene glycol ether; Nikkol TMGS 15; PEG-10 GLYCERYL STEARATE; PEG-120 GLYCERYL STEARATE; PEG-20 GLYCERYL STEARATE; PEG-200 GLYCERYL STEARATE; PEG-25 GLYCERYL STEARATE; PEG-30 GLYCERYL STEARATE; PEG-5 GLYCERYL STEARATE; Poly(oxy- 1, 2- ethanediyl), a- hydro- ?- hydroxy- , ether with 1, 2, 3- propanetriol monooctadecanoate (2:1); Poly(oxy- 1, 2- ethanediyl), a- hydroy- ?- hydroxy- , ether with 1, 2, 3- propanetriol monooctadecanoate; Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with 1,2,3-propanetriol monooctadecanoate (2:1); Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with 1,2,3-propanetriol monooctadecanoate (2:1); Diethoxylated methyl glucopyranoside 2,6-dioleate; Peg 120 Methyl Glucose Dioleate; Peg-120 Methyl Glucose Dioleate; PEG-120 methylglucosedioleate; PEG 120 METİL GLUKOZ DİOLEAT; PEG 120 METİL GLİKOZ DİOLAT; peg120 metilglukozdiolat; PEG-120 METHYLGLUCOSEDIOLEATE; PEG120METHYLGLUCOSEDIOLEATE; PEG120 METHYL GLUCOSE DIOLEATE; PEG120 methyl glucose dioleate; PEG120methylglucosedioleate; Macrogol 120 methyl glucose dioleate; methyl glucose dioleate; methyl gluceth-10; PEG-120 methyl glucose trioleate; Glucamate DOE-120; Diethoxylated methyl glucopyranoside 2,6-dioleate; Ethoxylated methyl glucoside dioleate; Macrogol 120 methylglucosedioleate; METHYL GLUCOSE DOLEATE; peg-120 metil glukoz dioleat; peg120metilglukozdioleat; PEG-120 METİL GLUKOZ DİOLEAT; PEG12METİLGLUKOZDİOLEAT; methil glukoze dioleat; 120peg methyl glucose dioleate; metilene glukoze dioleate; peg-120; PEG 120; PEG120; peg120; P E G 120; Macrogol 120 methil glucose dioleate; methyl glucose dioleat; methyl gluceth; PEG120 methyl glucose trioleate; GlucamateDOE120; Diethoxylatedmethylglucopyranoside 26-dioleate; Ethoxylatedmethyl glucoside dioleate; Macrogol120 methylglucosedioleate; METHYL GLUCOSE DOLEATE; Peg 120 Methyl Glucose Dioleate; Macrogol 120 methyl glucose dioleate; POE (120) methyl glucose dioleate; YM0K64F20V; 86893-19-8; Peg 120 Methyl Glucose Dioleate; Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with methyl D-glucopyranoside 2,6-di-(9Z)-9-octadecenoate (2:1); Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with methyl D-glucopyranoside 2,6-di-9-octadecenoate (2:1), (Z,Z)-; Diethoxylated methyl glucopyranoside 2,6-dioleate; UNII-YM0K64F20V; Ethoxylated methyl glucoside dioleate; Antil 120 Plus; Unitol 120 Plus; Peg 120 Methyl Glucose Dioleate; Poly(oxy-1,2-ethanediyl),a-hydro-w-hydroxy-, ether with methylD-glucopyranoside 2,6-di-9-octadecenoate (2:1), (Z,Z)- ; Peg 120 Methyl Glucose Dioleate; Glucamate DOE-120; Antil 120Plus; PEG 120 Methyl Glucose Dioleate; Diethoxylated methyl glucopyranoside 2,6-dioleate; Glucamate DOE 120; ose dioleate; Ethoxylated methyl glucoside dioleate; Diethoxylated methyl glucopyranoside 2,6-dioleate; Glucamate DOE 120, Antil 120 Plus,cas:86893-19-8; Diethoxylated methyl glucopyranoside 2,6-dioleate; UNII-YM0K64F20V; Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with methyl D-glucopyranoside 2,6-di-(9Z)-9-octadecenoate (2:1); Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with methyl D-glucopyranoside 2,6-di-9-octadecenoate (2:1), (Z,Z)-; Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl d-glucopyranoside 2,6-bis[(Z)-9-octadecenoate] (2:1) (120 mol EO average molar ratio); (C2-H4-O)mult-(C2-H4-O)mult-C21-H42-O4; 51158-08-8; Cutina E 24PF; Ethoxylated glyceryl monostearate; Glycerin monostearate polyethylene glycol ether; Nikkol TMGS 15; PEG-10 GLYCERYL STEARATE; PEG-120 GLYCERYL STEARATE; PEG-20 GLYCERYL STEARATE; PEG-200 GLYCERYL STEARATE; PEG-25 GLYCERYL STEARATE; PEG-30 GLYCERYL STEARATE; PEG-5 GLYCERYL STEARATE; Poly(oxy- 1, 2- ethanediyl), a- hydro- ?- hydroxy- , ether with 1, 2, 3- propanetriol monooctadecanoate (2:1); Poly(oxy- 1, 2- ethanediyl), a- hydroy- ?- hydroxy- , ether with 1, 2, 3- propanetriol monooctadecanoate; Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with 1,2,3-propanetriol monooctadecanoate (2:1); Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-, ether with 1,2,3-propanetriol monooctadecanoate (2:1)


PEG 120 Methyl Glucose Dioleate

A surfactant and emulsifier 
PEG 120 Methyl Glucose Dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid. It is used in beauty products and cosmetics as a surfactant and emulsifier. It is used as a thickener in hair and skin care products. It is considered a non-irritant, and also has a specific property that allows it to reduce the irritation value of whole formulas (Source). The high molecular weight of this specific PEG makes it impenetratable to healthy skin; it is FDA and CIR approved for use, but not on broken skin
Functions:
Despite the many fears regarding PEGs (including PEG 120 Methyl Glucose Dioleate), they are seen as an ingredient in a large number of products because of their diverse properties. In a study published in the Toxicology journal in 2005, entitled "Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products," it was concluded that: "Taking into consideration all available information from related compounds, as well as the mode and mechanism of action, no safety concern with regard to these endpoints could be identified. Based on the available data it is therefore concluded that PEGs of a wide molecular weight range (200 to over 10,000), their ethers (laureths, ceteths, ceteareths, steareths, and oleths), and fatty acid esters (laurates, dilaurates, stearates, distearates) are safe for use in cosmetics."
Safety Measures/Side Effects PEG 120 Methyl Glucose Dioleate:

Benefits:
•Very effective non-ionic, liquid thickener for various surfactant and emulsion systems
•Due to its liquid form it is easily incorporated into a wide range of products
•Excellent in cold processed formulations
•Can be used for clear surfactant systems
•Does not need to be neutralized with an alkali
•Recommended for mild cleansing systems to reduce irritancy of surfactants
Use: Use levels 0.5-3% depending on application and amount of thickening required. Note: at colder temperatures Glucose-D can solidify and become thick like a gel. For easier handling we recommend to put the bottle first into a water bath (about 50-60oC) for 10min. For external use only.

Applications: Body washes, shampoos, face cleansers.
Country of Origin: USA
Raw material source: Rapeseed oil, ethylene oxide
Manufacture: Peg 120 Methyl Glucose Dioleate and methyl gluceth-10 are produced from fatty acids and then reacted with ethylene oxide.

Peg 120 Methyl Glucose Dioleate is derived from corn, it is a thickening agent for mild cleansing systems, it also reduces the irritancy of surfactant packages. It is the polyethylene glycol ether of the diester of natural Methyl glucose and Oleic Acid. It is used in beauty products and cosmetics as a surfactant and emulsifier. It is used as a thickener in hair and skin care products. 
GlucamateTM DOE-120 thickener is an ethoxylated methyl glucose ether which has been esterified with oleic acid. It is an extremely effective nonionic thickener for hair care and skin care products. This product is recommended for use in shower gels, facial cleansers and shampoos.

TYPICAL PRODUCT SPECIFICATIONS
NOTES : Peg 120 Methyl Glucose Dioleate is a PEG ether of the diester of methyl glucose and oleic acid with avg. 120 moles of ethylene oxide Peg 120 Methyl Glucose Dioleate uses and applications include: Thickener, emulsifier, solubilizer for shampoos, cosmetics, topical pharmaceuticals; anti-irritant for surfactants
CLASS : Surfactants 
FUNCTIONS : Surfactant, Emulsifier, Acid 
INDUSTRY : Cosmetic, Pharmaceutical 
APPEARANCE Pale yellow flake Yellow-brown viscous liquid
FUNCTION : Peg 120 Methyl Glucose Dioleate is an extremely effective nonionic thickener for hair care and skin care products.
STORAGE : Store in a cool dry place. Store only with compatible chemicals. Keep tightly closed.
USE: It is a kind of high-efficient thickener in shampoo, body wash, facial cleanser and baby cleanser

Physical and Chemical Properties
Polypropylene glycol-20 methyl glucose ether acetate is soluble in oils and organic solvents, but is essentially insoluble in water.2 A log Kow of 13.98 has been reported for d-glucopyranoside, methyl, 2,6-di-9-octadecenoate, (Z,Z)-(Chemical Abstracts Service Number 82933-91-3), another name for methyl glucose dioleate.3 A log Kow ≈ 7.09 has been reported for methyl glucose sesquistearate.4 Specifications for methyl glucoside-coconut oil ester (methyl glucose sesquicocoate) as a direct food additive are as follows5: acid number (10-20), hydroxyl number (200-300), pH (4.8-5.0, for 5% aqueous), and saponification number (178-190). Physical and chemical properties associated with methyl glucose polyether and ester trade name materials are included in Tables 3, 4, and 5.6 Studies on most of these trade name materials are included in the toxicology section of this article. Additionally, the chemical and physical properties of isostearic acid (esters with methyl α-d-glucoside [registered with the European Chemicals Industry, ECHA], defined as 80% methyl glucoside isostearate esters [mainly di-], 16% isostearic acid, and 4% methyl glucoside)7 are included in Table 6. Data on this mixture are also included in the toxicology section.

Method of Manufacture
Methyl glucoside (methyl α-d-glucopyranoside) forms the backbone of the methyl glucose polyethers and esters reviewed in this safety assessment. It is cyclic or "internal" full acetal that is formed from 1 mole of methanol and 1 mole of glucose. It has been characterized as an unusually stable glucoside that exists in discrete α or β forms.16 The pathways for methyl glucoside ester and polyether methyl glucoside synthesis starting from methyl glucoside are diagrammed in Figure 1.Manufacture of methyl glucoside esters, such as methyl glucose caprylate/caprate, methyl glucose dioleate, methyl glucose isostearate, methyl glucose laurate, methyl glucose sesquicaprylate/sesquicaprate, methyl glucose sesquicocoate, methyl glucose sesquiisostearate, methyl glucose sesquilaurate, methyl glucose sesquioleate, and methyl glucose sesquistearate, is typically achieved via transesterification of an appropriate fatty acid methyl ester (eg, methyl laurate to get methyl glucose laurate) with methyl glucoside (releasing methanol as a by-product).8-13 However, esterifications via a variety of other classical techniques, such as reacting the free fatty acids with methyl glucoside and a catalyst, are also known methods of manufacture for these ingredients.14,15 Under most conditions, the primary alcohol group at C6 of the methyl glucoside core is the most reactive to esterification and is the first site to be substituted. The polyether methyl glucosides, such as PPG-10 methyl glucose ether, PPG-20 methyl glucose ether, PPG-25 methyl glucose ether, methyl gluceth-10, and methyl gluceth-20, are typically manufactured by reaction of methyl glucoside with the required amount of the appropriate epoxide (eg, propylene oxide is used to produce PPG-10 methyl glucose; ethylene oxide is utilized to produce methyl gluceth-10).10 For those ingredients with both ester and polyether groups, such as Peg 120 Methyl Glucose Dioleate, PEG-20 methyl glucose distearate, PEG-80 methyl glucose laurate, PEG-20 methyl glucose sesquicaprylate/sesquicaprate, PEG-20 methyl glucose sesquilaurate, PEG-20 methyl glucose sesquistearate, PEG-120 methyl glucose triisostearate, PEG-120 methyl glucose trioleate, PPG-20 methyl glucose ether acetate, and PPG-20 methyl glucose ether distearate, these same methods are utilized, sequentially. An example would be PEG-80 methyl glucose laurate, which is produced in 2 steps: (1) esterification of methyl glucoside with methyl laurate, followed by (2) polyetherification with ethylene oxide.

Use
Cosmetic
The methyl glucose polyethers reportedly function as skin and hair-conditioning agents, whereas, the methyl glucose esters reportedly function only as skin-conditioning agents in cosmetic products.1 Ingredients classified as both methyl glucose polyethers and esters based on their chemical structures function as skin-conditioning agents, surfactants, and viscosity-increasing agents in cosmetic products. According to the information supplied to the Food and Drug Administration (FDA) by industry as part of the Voluntary Cosmetic Registration Program (VCRP) in 2013 (summarized in Table 7), methyl glucose dioleate, methyl glucose sesquioleate, methyl glucose sesquistearate, PPG-10 methyl glucose ether, PPG-20 methyl glucose ether, PPG-20 methyl glucose ether distearate, methyl gluceth-10, methyl gluceth-20, Peg 120 Methyl Glucose Dioleate, PEG-20 methyl glucose distearate, PEG-20 methyl glucose sesquistearate, and PEG-120 methyl glucose trioleate are being used in cosmetic products.17 A survey of ingredient use concentrations that was conducted by the Personal Care Products Council (Council) in 2013 (Table 7) indicates that the polyethers and esters are being used at concentrations up to 15% and 4%, respectively.18,19 The maximum use concentration was 15% for methyl gluceth-10 and methyl gluceth-20 used in rinse-off skin-cleansing products. For leave-on products, the 15% maximum use concentration was for methyl gluceth-10 used in face and neck creams, lotions, and powders (not sprays). The Council survey results also provided a use concentration for the newly reported VCRP use(s) of methyl glucose sesquistearate (1% maximum use concentration), but not PEG-20 methyl glucose sesquistearate, in lipsticks. Additionally, a maximum use concentration of 0.05% for PEG-20 methyl glucose distearate in lipsticks was reported in this survey. Uses of methyl glucose sesquistearate and PEG-20 methyl glucose sesquistearate, but not PEG-20 methyl glucose distearate, in lipsticks were also reported in FDA's VCRP. Cosmetic products containing methyl glucose polyethers and esters may be applied to the skin and hair, or, incidentally, may come in contact with the eyes and mucous membranes. Products containing these ingredients may be applied as frequently as several times per day and may come in contact with the skin or hair for variable periods following application. Daily or occasional use may extend over many years.

PEG 120 methyl glucose dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid. PEG 120 methyl glucose dioleate is used in beauty products and cosmetics as a surfactant and emulsifier. PEG 120 methyl glucose dioleate is used as a thickener in hair and skin care products. PEG 120 methyl glucose dioleate is considered a non-irritant, and also has a specific property that allows PEG 120 methyl glucose dioleate to reduce the irritation value of whole formulas (Source). The high molecular weight of this specific PEG 120 methyl glucose dioleate impenetratable to healthy skin; PEG 120 methyl glucose dioleate  is FDA and CIR approved for use, but not on broken skin PEG 120 methyl glucose dioleate thickener is an ethoxylated methyl glucose ether which has been esterified with oleic acid. PEG 120 methyl glucose dioleate is an extremely effective nonionic thickener for hair care and skin care products. 
PEG 120 methyl glucose dioleate is recommended for use in shower gels, facial cleansers and shampoos. PEG 120 methyl glucose dioleate is a very popular skin care ingredient and are used to dissolve oil and grease. PEG 120 methyl glucose dioleate is used in skin care products as thickeners and stabalizers, and to PEG 120 methyl glucose dioleate help dissolve oil on skin. PEG 120 methyl glucose dioleate is an extremely effective non-ionic thickener for hair care and skin care products, PEG 120 methyl glucose dioleate recommended in shower gels, PEG 120 methyl glucose dioleate recommended in facial cleansers and PEG 120 methyl glucose dioleate recommended in shampoos. Actives: 70-80%. Remaining part: water. PEG 120 methyl glucose dioleate is viscous liquid, PEG 120 methyl glucose dioleate light yellow color. An LD50 of > 5 g/kg was also reported for PEG 120 methyl glucose dioleate in a study involving rats (number and strain not stated). PEG 120 methyl glucose dioleate Details relating to the test protocol were not stated. The ocular irritation potential of PEG 120 methyl glucose dioleate was evaluated in the Draize test using 5 male or female New Zealand albino rabbits.37 The test substance (100 µl) was instilled into one eye of each animal. Instillation was followed by massaging for 30 seconds. Untreated eyes served as controls. Reactions were scored at 24 h, 48 h, 72 h, and 7 days post-instillation PEG 120 methyl glucose dioleate , and maximum average Draize scores (MAS; range: 0 to 110) were determined. PEG 120 methyl glucose dioleate was classified as a slight irritant (maximum average Draize score = 8.8). An in vitro assay was conducted to determine if there was a correlation with the in vivo Draize test conducted on rabbits. PEG 120 methyl glucose dioleate Using sheep red blood cells, this in vitro assay assessed hemolysis and protein denaturation. The extent of hemolysis was determined spectrophotometrically. 

Assay results for PEG 120 methyl glucose dioleate were as follows: effective concentration that caused 50% hemolysis (H50) = 1,125.56 µg/ml; denaturation index (DI) = 12.82%; H50/DI = 87.80. The Pearson and Spearman PEG 120 methyl glucose dioleate correlation coefficients between the log H50/DI and the MAS were 0.752 and 0.705, respectively. Thus, PEG 120 methyl glucose dioleate was also classified as a slight irritant in the in vitro assay. The ocular irritation potential of 100% PEG 120 methyl glucose dioleate was evaluated in the Draize test using rabbits (number and strain not stated).32 The test substance did not induce ocular irritation. In comparative irritation tests, PEG 120 methyl glucose dioleate (concentrations not stated) significantly reduced the ocular irritation induced by SLS and AOS in rabbits (number and strain not stated). The PEG 120 methyl glucose dioleate abbreviated chemical names were not defined. The skin irritation potential of 100% The PEG 120 methyl glucose dioleate (GlucamTM DOE-120 Thickener) was evaluated using rabbits (number and strain not stated).32 Details relating to the test protocol were not included. A primary irritation The PEG 120 methyl glucose dioleate index of 0.45 (range: 0 to 8) was reported. % PEG 120 methyl glucose dioleate was evaluated in an HRIPT (occlusive patches) involving 53 atopic volunteers. n the Ames plate incorporation test, the genotoxicity of PEG 120 methyl glucose dioleate (in ethanol) was evaluated at doses up to 5000 µg/plate. 
It was concluded that PEG 120 methyl glucose dioleate was not genotoxic in any of the bacterial strains tested, with or without metabolic activation. PEG 120 methyl glucose dioleate is derived from corn, PEG 120 methyl glucose dioleate is a thickening agent for mild cleansing systems, PEG 120 methyl glucose dioleate also reduces the irritancy of surfactant packages. PEG 120 methyl glucose dioleate is the polyethylene glycol ether of the diester of natural Methyl glucose and Oleic Acid. PEG 120 methyl glucose dioleate is used in beauty products and cosmetics as a surfactant and emulsifier. PEG 120 methyl glucose dioleate is used as a thickener in hair and skin care products. Ingredients: PEG 120 methyl glucose dioleate : PEG 120 methyl glucose dioleate is a naturally derived cleansing and thickening agent for shampoos and other cleansing products. PEG 120 methyl glucose dioleate also has good moisture retention properties which can help PEG 120 methyl glucose dioleate improve the skin-feel of surfactant-based products. PEG 120 methyl glucose dioleate is derived from corn and palm and then ethoxylated to make PEG 120 methyl glucose dioleate wate soluble. PEG 120 methyl glucose dioleate is usually a petrochemical process. PEG 120 methyl glucose dioleate Soluble in hot water. PEG 120 methyl glucose dioleate comes as flakes that will soften and dissolve into a water base but PEG 120 methyl glucose dioleate can be quite slow at room temperature. The best procedure is to heat a little of your water to 50-60C and add the PEG 120 methyl glucose dioleate , forming a fluid paste which can then be added into the rest of your formula for thickening. 

PEG 120 methyl glucose dioleate uses as a thickening and cleansing agent for shampoos and cleansing products. PEG 120 methyl glucose dioleate is Polyethylene glycol ether of the diester of methyl glucose and oleic acid with an average of 120 moles of ethylene oxide. PEG 120 methyl glucose dioleate Surfactant/thickener/solubilizer/emulsifier mainly used in cosmetics and personal care products. For those ingredients with both ester and polyether groups, such as PEG 120 methyl glucose dioleate , PEG-20 methyl glucose distearate, PEG 120 methyl glucose dioleate , PEG-20 methyl glucose sesquicaprylate/sesquicaprate, PEG 120 methyl glucose dioleate PEG-20 methyl glucose sesquistearate, PEG-120 methyl glucose triisostearate, PEG-120 methyl glucose trioleate, PPG-20 methyl glucose ether acetate, and PEG 120 methyl glucose dioleate these same methods are utilized, sequentially. PEG 120 methyl glucose dioleate is a PEG 120 methyl glucose dioleate ether of the diester of methyl glucose and oleic acid with avg. 120 moles of ethylene oxide PEG 120 methyl glucose dioleate uses and applications include: PEG 120 methyl glucose dioleate is used as Thickener, PEG 120 methyl glucose dioleate is used as emulsifier, PEG 120 methyl glucose dioleate is used as solubilizer for shampoos, PEG 120 methyl glucose dioleate is used in cosmetics, topical pharmaceuticals; anti-irritant for surfactants. PEG 120 methyl glucose dioleate is commonly included in medications in the following forms. Cas no of PEG 120 methyl glucose dioleate is 86893-19-8. PEG 120 methyl glucose dioleate ; DOE 120 is an extremely effective nonionic thickener for hair care and skin care products, derives from natural methyl glucoside. And it has non-irritation for eyes, which ideally is applied for baby shampoos and face wash products. It is a good ingredient for low irritation formulation, based on its specific property梔istinctly reduce the irritation of whole formulation.

Appearance of PEG 120 methyl glucose dioleate     Pale yellow flake liquid
Odor of PEG 120 methyl glucose dioleate     Mild characteristic
Acid value, mg/g of PEG 120 methyl glucose dioleate     1MAX
Hydroxyl value, mg/g of PEG 120 methyl glucose dioleate     14-26
Saponification value, mg/g of PEG 120 methyl glucose dioleate     14-26
Iodine value of PEG 120 methyl glucose dioleate     5-15
pH,(5% aqueous solution) of PEG 120 methyl glucose dioleate     4.5-8.0
PEG 120 methyl glucose dioleate : PEG 120 methyl glucose dioleate is a polyethylene glycol ether of the diester of methylglucose and oleic acid with an average of 120 moles of ethylene oxide. PEG 120 methyl glucose dioleate is used in skin care and hair care products as a surfactant and emulsifier. PEG 120 methyl glucose dioleate is considered a non-irritant, and also has a specific property that allows PEG 120 methyl glucose dioleate to reduce the irritation value of whole formulas. PEG 120 methyl glucose dioleate is known to be a moderate hazard depending on use and warns of contamination and toxicity concerns. PEG 120 methyl glucose dioleate including products should not be used on broken or irritated skin as studies showed that patients suffering from severe burns treated with PEG 120 methyl glucose dioleate based antimicrobial cream has resulted in kidney toxicity. PEG 120 methyl glucose dioleate is also known to increase the incidences of uterine and breast cancers and of leukemia and brain cancer according to a study published in the PEG 120 methyl glucose dioleate International Journal of Toxicology. 
PEG 120 methyl glucose dioleate is FDA and CIR approved for use, but not on broken skin. PEG 120 methyl glucose dioleate is a naturally derived cleansing and thickening agent for shampoos and other cleansing products. PEG 120 methyl glucose dioleate also has good moisture retention properties which can help PEG 120 methyl glucose dioleate improve the skin-feel of surfactant-based products. PEG 120 methyl glucose dioleate is a very popular skin care ingredient and are used to dissolve oil and grease. PEG 120 methyl glucose dioleate is used in skin care products as thickeners and stabalizers, and to PEG 120 methyl glucose dioleate help dissolve oil on skin. PEG 120 methyl glucose dioleate is an extremely effective non-ionic thickener for hair care and skin care products, PEG 120 methyl glucose dioleate recommended in shower gels, PEG 120 methyl glucose dioleate recommended in facial cleansers and PEG 120 methyl glucose dioleate recommended in shampoos. Actives: 70-80%. Remaining part: water. PEG 120 methyl glucose dioleate is viscous liquid, PEG 120 methyl glucose dioleate light yellow color. An LD50 of > 5 g/kg was also reported for PEG 120 methyl glucose dioleate in a study involving rats (number and strain not stated). 

PEG 120 methyl glucose dioleate Details relating to the test protocol were not stated. The ocular irritation potential of PEG 120 methyl glucose dioleate was evaluated in the Draize test using 5 male or female New Zealand albino rabbits.37 The test substance (100 µl) was instilled into one eye of each animal. Instillation was followed by massaging for 30 seconds. Untreated eyes served as controls. Reactions were scored at 24 h, 48 h, 72 h, and 7 days post-instillation PEG 120 methyl glucose dioleate , and maximum average Draize scores (MAS; range: 0 to 110) were determined. PEG 120 methyl glucose dioleate was classified as a slight irritant (maximum average Draize score = 8.8). An in vitro assay was conducted to determine if there was a correlation with the in vivo Draize test conducted on rabbits. PEG 120 methyl glucose dioleate Using sheep red blood cells, this in vitro assay assessed hemolysis and protein denaturation. The extent of hemolysis was determined spectrophotometrically. Assay results for PEG 120 methyl glucose dioleate were as follows: effective concentration that caused 50% hemolysis (H50) = 1,125.56 µg/ml; denaturation index (DI) = 12.82%; H50/DI = 87.80. The Pearson and Spearman PEG 120 methyl glucose dioleate correlation coefficients between the log H50/DI and the MAS were 0.752 and 0.705, respectively. Thus, PEG 120 methyl glucose dioleate was also classified as a slight irritant in the in vitro assay. The ocular irritation potential of 100% PEG 120 methyl glucose dioleate was evaluated in the Draize test using rabbits (number and strain not stated).32 The test substance did not induce ocular irritation. In comparative irritation tests, PEG 120 methyl glucose dioleate (concentrations not stated) significantly reduced the ocular irritation induced by SLS and AOS in rabbits (number and strain not stated). The PEG 120 methyl glucose dioleate abbreviated chemical names were not defined. The skin irritation potential of 100% The PEG 120 methyl glucose dioleate (GlucamTM DOE-120 Thickener) was evaluated using rabbits (number and strain not stated).32 Details relating to the test protocol were not included. A primary irritation The PEG 120 methyl glucose dioleate index of 0.45 (range: 0 to 8) was reported. % PEG 120 methyl glucose dioleate was evaluated in an HRIPT (occlusive patches) involving 53 atopic volunteers. n the Ames plate incorporation test, the genotoxicity of PEG 120 methyl glucose dioleate (in ethanol) was evaluated at doses up to 5000 µg/plate. It was concluded that PEG 120 methyl glucose dioleate was not genotoxic in any of the bacterial strains tested, with or without metabolic activation.

PEG 120 methyl glucose dioleate thickener is non-irritating to the eyes, making PEG 120 methyl glucose dioleate ideal for baby shampoos. PEG 120 methyl glucose dioleate Broad compatibility with various surfactant systems PEG 120 methyl glucose dioleate Enables formulations that are easy to pour and have aesthetically-pleasing foaming properties without the worry of changing foam characteristics PEG 120 methyl glucose dioleate Enables very mild formulations and reduces irritation associated with certain surfactants for application around the eyes. PEG 120 methyl glucose dioleate Highly efficient thickener of surfactant system formulations PEG 120 methyl glucose dioleate Naturally derive PEG 120 methyl glucose dioleate Very light feel. PEG 120 methyl glucose dioleate is used as Body Washes.PEG 120 methyl glucose dioleate is used as Body Washes PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Facial Cleansers. PEG 120 methyl glucose dioleate is used as Hand Soap.PEG 120 methyl glucose dioleate is used as Intimate Cleansers.PEG 120 methyl glucose dioleate is used as Mild Cleansers. PEG 120 methyl glucose dioleate is used as Shampoo. PEG 120 methyl glucose dioleate is a natural glucose derivative from corn, acting as high–efficient thickener in shampoo, body wash, facial cleanser and baby cleanser. PEG 120 methyl glucose dioleate is especially applicable to some surfactants hardly to thicken. PEG 120 methyl glucose dioleate causes no irritation to eyes, meanwhile significantly reduces irritation of whole formula.PEG 120 methyl glucose dioleate - PEG 120 methyl glucose dioleate Superior ability to thicken many anionic and amphoteric surfactants.

PEG 120 methyl glucose dioleate No irritation to eye, applicable in facial cleanser and baby shampoo. PEG 120 methyl glucose dioleate  No effect on foamability. PEG 120 methyl glucose dioleate Impart quite soft and gentle after-feeling.PEG 120 methyl glucose dioleate is used in Shampoo, body wash, facial cleanser.PEG 120 methyl glucose dioleate Typically used at a level of 0.1-5.0%. PEG 120 methyl glucose dioleate is extremely valued by the clients. PEG 120 methyl glucose dioleate is available with us at market leading prices. CAS Number of PEG 120 methyl glucose dioleate 86893-19-8 Linear Formula of PEG 120 methyl glucose dioleate C45H81O10. Molecular Weight of PEG 120 methyl glucose dioleate 782.12. PEG 120 methyl glucose dioleate holds a significant share in the overall market. PEG 120 methyl glucose dioleate functions as a surfactant and emulsifier in skincare and haircare products. PEG 120 methyl glucose dioleate does not cause irritation and is considered to minimize the irritation value of whole formulas. Moreover, PEG 120 methyl glucose dioleate , a corn-sugar derived active cosmetic ingredient, is projected to grow at a considerable rate over the forecast timeframe. PEG 120 methyl glucose dioleate offers water-retention characteristics to prevent water-loss from the skin along with emulsifying & thickening properties. PEG 120 methyl glucose dioleate is a flaked solid, highly efficient viscosity builder designed for use with numerous anionic surfactants and amphoteric surfactant systems PEG 120 methyl glucose dioleate popular in many shampoos, body washes, and liquid soaps. PEG 120 methyl glucose dioleate thickener is non-irritating to the eyes, making PEG 120 methyl glucose dioleate ideal for baby shampoos.

PEG 120 methyl glucose dioleate is a kind of mild non-ionic thickening agent, it can reduce formula irritation. PEG 120 methyl glucose dioleate is high-efficient thickener for rinse-off products, even for some surfactants which are hard to be thickening. PEG 120 methyl glucose dioleate Effective nonionic thickener for hair care and skin care products. . PEG 120 methyl glucose dioleate Highly efficient thickener of surfactant system formulations PEG 120 methyl glucose dioleate Naturally derive PEG 120 methyl glucose dioleate Very light feel. PEG 120 methyl glucose dioleate is used as Body Washes.PEG 120 methyl glucose dioleate is used as Body Washes PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Facial Cleansers. PEG 120 methyl glucose dioleate is used as Hand Soap.PEG 120 methyl glucose dioleate is used as Intimate Cleansers.PEG 120 methyl glucose dioleate is used as Mild Cleansers. PEG 120 methyl glucose dioleate is used as Shampoo. PEG 120 methyl glucose dioleate is a natural glucose derivative from corn, acting as high–efficient thickener in shampoo, body wash, facial cleanser and baby cleanser. PEG 120 methyl glucose dioleate is especially applicable to some surfactants hardly to thicken. PEG 120 methyl glucose dioleate causes no irritation to eyes, meanwhile significantly reduces irritation of whole formula.PEG 120 methyl glucose dioleate -     PEG 120 methyl glucose dioleate Superior ability to thicken many anionic and amphoteric surfactants.
Majorly be used as emulsifier, thickener, plasticizer etc. Solubility of PEG 120 methyl glucose dioleate : slightly soluble in water. PEG 120 methyl glucose dioleate Stability: Stable under strong acid, strong alkaline condition, PEG 120 methyl glucose dioleate is easy to hydrolyze, easily be oxidized. PEG 120 methyl glucose dioleate Biodegradation: biodegradable. PEG 120 methyl glucose dioleate Characteristics: A surfactant and emulsifier 
PEG 120 Methyl Glucose Dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid.

PEG 120 Methyl Glucose Dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid. It is used in beauty products and cosmetics as a surfactant and emulsifier. It is used as a thickener in hair and skin care products. It is considered a non-irritant, and also has a specific property that allows it to reduce the irritation value of whole formulas (Source). The high molecular weight of this specific PEG makes it impenetratable to healthy skin; it is FDA and CIR approved for use, but not on broken skin.
Despite the many fears regarding PEGs (including PEG 120 Methyl Glucose Dioleate), they are seen as an ingredient in a large number of products because of their diverse properties. In a study published in the Toxicology journal in 2005, entitled "Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products," it was concluded that: "Taking into consideration all available information from related compounds, as well as the mode and mechanism of action, no safety concern with regard to these endpoints could be identified. Based on the available data it is therefore concluded that PEGs of a wide molecular weight range (200 to over 10,000), their ethers (laureths, ceteths, ceteareths, steareths, and oleths), and fatty acid esters (laurates, dilaurates, stearates, distearates) are safe for use in cosmetics."
PEG 120 methyl glucose dioleate is derived from corn, it is a thickening agent for mild cleansing systems, it also reduces the irritancy of surfactant packages. It is the polyethylene glycol ether of the diester of natural Methyl glucose and Oleic Acid. It is used in beauty products and cosmetics as a surfactant and emulsifier. It is used as a thickener in hair and skin care products. 
GlucamateTM DOE-120 thickener is an ethoxylated methyl glucose ether which has been esterified with oleic acid. It is an extremely effective nonionic thickener for hair care and skin care products. This product is recommended for use in shower gels, facial cleansers and shampoos.

Use
PEG 120 methyl glucose dioleate (DOE-120) has good properties of emulsifying, dispersing, solubilization etc. PEG 120 methyl glucose dioleate is compatible to skin, feel comfortable.PEG 120 methyl glucose dioleate is naturally derived product. PEG 120 methyl glucose dioleate has very good compatibility, PEG 120 methyl glucose dioleate won’t decrease the foam of the surfactant system, PEG 120 methyl glucose dioleate has good compatibility and thickening function using together with AOS, SLES, Sulfosuccinate and ampho-surfactant.PEG 120 methyl glucose dioleate (DOE-120) has no jelly feeling, PEG 120 methyl glucose dioleate have superior cooperativity.PEG 120 methyl glucose dioleate (DOE-120) thickening agent has very mild irritation to eye, test result shows the irritation to eye is zero, so PEG 120 methyl glucose dioleate is ideal and perfect raw material of infant shampoo.Besides, PEG 120 methyl glucose dioleate (DOE-120) can remarkably decrease the irritation to eye of other surfactants. Because of thickening of PEG 120 methyl glucose dioleate and irritation of PEG 120 methyl glucose dioleate relieving function, PEG 120 methyl glucose dioleate is suitable to be produce cleaning products.The formula designer can adopt PEG 120 methyl glucose dioleate to produce pourable product which can produce beautiful foams, and meanwhile you don’t worry the foam characteristics are changed. PEG 120 methyl glucose dioleate (DOE-120) is widely used for producing infant shampoo, facial cleaning cream, hand washing liquid, mild shampoo, body washing liquid, make up remover etc.PEG 120 methyl glucose dioleate (DOE-120) has excellent mildness, PEG 120 methyl glucose dioleate is high effective thickening agent in surfactant system. PEG 120 methyl glucose dioleate can decrease the irritation brought by surfactants, PEG 120 methyl glucose dioleate won’t decrease the height of the foam.Recommended dosage: 0.1-5.0%. To study and analyze the global PEG 120 methyl glucose dioleate consumption (value & volume) by key regions/countries, type and application, history data from 2015 to 2019, and forecast to 2025. To understand the structure of PEG 120 methyl glucose dioleate market by identifying its various subsegments. Focuses on the key global PEG 120 methyl glucose dioleate manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years. To analyze the PEG 120 methyl glucose dioleate with respect to individual growth trends, future prospects, and their contribution to the total market. To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks). To project the consumption of PEG 120 methyl glucose dioleate submarkets, with respect to key regions (along with their respective key countries PEG 120 methyl glucose dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid. PEG 120 methyl glucose dioleate is used in beauty products and cosmetics as a surfactant and emulsifier. PEG 120 methyl glucose dioleate is used as a thickener in hair and skin care products. 

PEG 120 methyl glucose dioleate is high-efficient thickener for rinse-off products, even for some surfactants which are hard to be thickening. PEG 120 methyl glucose dioleate Effective nonionic thickener for hair care and skin care products. . PEG 120 methyl glucose dioleate Highly efficient thickener of surfactant system formulations PEG 120 methyl glucose dioleate Naturally derive PEG 120 methyl glucose dioleate Very light feel. PEG 120 methyl glucose dioleate is used as Body Washes.PEG 120 methyl glucose dioleate is used as Body Washes PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate (DOE-120) has good properties of emulsifying, dispersing, solubilization etc. PEG 120 methyl glucose dioleate is compatible to skin, feel comfortable.PEG 120 methyl glucose dioleate is naturally derived product. PEG 120 methyl glucose dioleate has very good compatibility, PEG 120 methyl glucose dioleate won’t decrease the foam of the surfactant system, PEG 120 methyl glucose dioleate has good compatibility and thickening function using together with AOS, SLES, Sulfosuccinate and ampho-surfactant.

PEG 120 methyl glucose dioleate (DOE-120) has no jelly feeling, PEG 120 methyl glucose dioleate have superior cooperativity.PEG 120 methyl glucose dioleate (DOE-120) thickening agent has very mild irritation to eye, test result shows the irritation to eye is zero, so PEG 120 methyl glucose dioleate is ideal and perfect raw material of infant shampoo.Besides, PEG 120 methyl glucose dioleate (DOE-120) can remarkably decrease the irritation to eye of other surfactants. Because of thickening of PEG 120 methyl glucose dioleate and irritation of PEG 120 methyl glucose dioleate relieving function, PEG 120 methyl glucose dioleate is suitable to be produce cleaning products.The formula designer can adopt PEG 120 methyl glucose dioleate to produce pourable product which can produce beautiful foams, and meanwhile you don’t worry the foam characteristics are changed. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Body Washes. PEG 120 methyl glucose dioleate is used as Facial Cleansers. PEG 120 methyl glucose dioleate is used as Hand Soap.PEG 120 methyl glucose dioleate is used as Intimate Cleansers.PEG 120 methyl glucose dioleate is used as Mild Cleansers. PEG 120 methyl glucose dioleate is used as Shampoo. PEG 120 methyl glucose dioleate is a natural glucose derivative from corn, acting as high–efficient thickener in shampoo, body wash, facial cleanser and baby cleanser. PEG 120 methyl glucose dioleate is especially applicable to some surfactants hardly to thicken. PEG 120 methyl glucose dioleate causes no irritation to eyes, meanwhile significantly reduces irritation of whole formula.PEG 120 methyl glucose dioleate - PEG 120 methyl glucose dioleate is considered a non-irritant, and also has a specific property that allows PEG 120 methyl glucose dioleate to reduce the irritation value of whole formulas. The high molecular weight of this specific PEG makes it impenetratable to healthy skin; it is FDA and CIR approved for use, but not on broken skin. Solubility of PEG 120 methyl glucose dioleate : slightly soluble in water. PEG 120 methyl glucose dioleate Stability: Stable under strong acid, strong alkaline condition, PEG 120 methyl glucose dioleate is easy to hydrolyze, easily be oxidized. PEG 120 methyl glucose dioleate Biodegradation: biodegradable. 

PEG 120 methyl glucose dioleate Characteristics:
PEG 120 methyl glucose dioleate (DOE-120) has good properties of emulsifying, dispersing, solubilization etc. PEG 120 methyl glucose dioleate is compatible to skin, feel comfortable.PEG 120 methyl glucose dioleate is naturally derived product. PEG 120 methyl glucose dioleate has very good compatibility, PEG 120 methyl glucose dioleate won’t decrease the foam of the surfactant system, PEG 120 methyl glucose dioleate has good compatibility and thickening function using together with AOS, SLES, Sulfosuccinate and ampho-surfactant.PEG 120 methyl glucose dioleate (DOE-120) has no jelly feeling, PEG 120 methyl glucose dioleate have superior cooperativity.PEG 120 methyl glucose dioleate (DOE-120) thickening agent has very mild irritation to eye, test result shows the irritation to eye is zero, so PEG 120 methyl glucose dioleate is ideal and perfect raw material of infant shampoo.Besides, PEG 120 methyl glucose dioleate (DOE-120) can remarkably decrease the irritation to eye of other surfactants. Because of thickening of PEG 120 methyl glucose dioleate and irritation of PEG 120 methyl glucose dioleate relieving function, PEG 120 methyl glucose dioleate is suitable to be produce cleaning products.The formula designer can adopt PEG 120 methyl glucose dioleate to produce pourable product which can produce beautiful foams, and meanwhile you don’t worry the foam characteristics are changed. PEG 120 methyl glucose dioleate (DOE-120) is widely used for producing infant shampoo, facial cleaning cream, hand washing liquid, mild shampoo, body washing liquid, make up remover etc.PEG 120 methyl glucose dioleate (DOE-120) has excellent mildness, PEG 120 methyl glucose dioleate is high effective thickening agent in surfactant system.

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