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PEG (20) SORBITAN MONOLAURATE (POLYSORBATE 20)

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is a polysorbate-type nonionic surfactant
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is formed by the ethoxylation of sorbitan monolaurate. 
PEG (20) Sorbitan Monolaurate (Polysorbate 20)'s stability allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications.


CAS NUMBER: 9005-64-5

EC NUMBER: 500-018-3

MOLECULAR FORMULA: C26H50O10

MOLECULAR WEIGHT: 522.7

IUPAC NAME: 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is a complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
As the name implies the ethoxylation process leaves the molecule with 20 repeat units of polyethylene glycol; in practice these are distributed across 4 different chains, leading to a commercial product containing a range of chemical species.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as a wetting agent in flavored mouth drops such as Ice Drops, helping to provide a spreading feeling to other ingredients like SD alcohol and mint flavor.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as an excipient in pharmaceutical applications to stabilize emulsions and suspensions.

APPLICATIONS: 
Biotechnical Applications:
In biological techniques and sciences, PEG (20) Sorbitan Monolaurate (Polysorbate 20) has a broad range of applications. 

For example, PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used:
*as a washing agent in immunoassays
PEG (20) Sorbitan Monolaurate (Polysorbate 20) helps to prevent non-specific antibody binding. 
These buffers are used for washes between each immunoreaction, to remove unbound immunologicals, and eventually for incubating solutions of immunoreagents (labeled antibodies) to reduce nonspecific background.

*to saturate binding sites on surfaces (i.e., to coat polystyrene microplates, generally combined with proteins such as BSA).

*to stabilize proteins purified protein derivative (PPD) solution used in skin testing for tuberculosis exposure

*as a solubilizing agent of membrane proteins

*for lysing mammalian cells, at a concentration of 0.05% to 0.5% v/v, generally combined with other detergents, salts and additives.


Industrial and Domestic Applications:
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in many brands of baby wipes.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is also used as wetting agent in rubber balers in the elastomer industry.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) has been used as a shape directing agent to synthesize spheroidal magnetite nanoassemblies

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is a non-ionic detergent that is routinely used in biochemical and life science research.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is non-ionic detergent for solubilizing membrane proteins during isolation of membrane-protein complexes

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is ultra low concentrations of contaminating peroxides, aldehydes, salts and carbonyl compounds
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is a surfactant and emulsifier used in cleaners and personal care products.

PEG (20) Sorbitan Monolaurate (Polysorbate 20), in its original form, is a harmless sorbitol (sugar alcohol). 
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in personal care products

PEG (20) Sorbitan Monolaurate (Polysorbate 20)'s common name is polysorbate 20.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as an emulsifier (mixing oil and water). 

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is an ingredient in baby oil
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in cosmetic creams, cream deodorant, lotions, and sun lotion.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is a liquid emulsifier that helps water and oil combine. 
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is ideal for use in room sprays, toners and liquid based products

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is regarded as a safe chemical in skincare
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as an emulsifier to combine oil and water.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in room sprays
PEG (20) Sorbitan Monolaurate (Polysorbate 20) can also be used in a bath oils

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in cream preparations and shower gels / shampoos to aid stability and solubilisation.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is soothing to the skin.

Common Usage Areas:
-Emulsifier
-Solubiliser
-Sorbitol
-Stabiliser
-Dispersant
 
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is typically used in the following products:
-Toner
-Room Spray
-Moisture Cream
-Moisture Lotion
-Cleansers
-Shower Gel
-Shampoo
-Hair Treatments

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is derived from sorbitol, a natural sugar alcohol
PEG (20) Sorbitan Monolaurate (Polysorbate 20) forms a polysorbate-type nonionic surfactant by the ethoxylation of sorbitan

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is nontoxic
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is stable

PEG (20) Sorbitan Monolaurate (Polysorbate 20) can be used as a emulsifier and detergent
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in scientific, and pharmacological applications. 

PEG (20) Sorbitan Monolaurate (Polysorbate 20) functions as a good wetting agent having food application in flavoured mouth drops
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is providing a spreading feeling to other added flavour ingredients. 

In biochemical applications, PEG (20) Sorbitan Monolaurate (Polysorbate 20) finds use as washing agent in solubilizing agent for membrane proteins, and lysis solutions for mammalian cells. 
While in the pharma sector, PEG (20) Sorbitan Monolaurate (Polysorbate 20) functions as an excipient helping to stabilize emulsions and suspensions. 
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is safe for use in cosmetic formulations.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is an ingredient used in skincare and cosmetic formulations to improve the texture, feel, and scent of the product. 
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is mainly used as a surfactant, emulsifier, and fragrance ingredient.


PHYSICAL PROPERTIES: 

-Molecular Weight: 522.7

-XLogP3-AA: 2.5        

-Exact Mass: 522.34039779    

-Monoisotopic Mass: 522.34039779

-Topological Polar Surface Area: 133 Ų

-Physical Description: Yellow viscous liquid

-Color: Lemon- to amber-colored

-Form: Liquid

-Odor: Characteristic odor

-Taste: Bitter

-Melting Point: 110 °C

-Solubility: Soluble in water, alcohol, ethyl acetate, methanol, dioxane

-Density: 1.095 g/mL

-Refractive Index: 1.468


PEG (20) Sorbitan Monolaurate (Polysorbate 20) is a mild nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid which is a medium-chain fatty acid found mainly in coconut oil. 
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as the emulsifier, detergent, dispersant, solvent and stabilizer, etc. in a number of fields such as pharmaceutical, chemical, food, textile and other industries due to its stability and relative non-toxicity.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is widely applied in biological techniques and sciences.
Besides, PEG (20) Sorbitan Monolaurate (Polysorbate 20) also has applications in food production as a common food grade additive
PEG (20) Sorbitan Monolaurate (Polysorbate 20) can also be used as a wetting agent in flavored mouth drops such as Ice Drops, in oral or non-gastrointestinal suspensions and in rubber balers in the elastomer industry.


CHEMICAL PROPERTIES: 

-Hydrogen Bond Donor Count: 3

-Hydrogen Bond Acceptor Count: 10    

-Rotatable Bond Count: 26

-Heavy Atom Count: 36    

-Formal Charge: 0    

-Complexity: 507    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 4    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 1    

-Compound Is Canonicalized: Yes

-Chemical Classes: Other Classes -> Polyoxyethylenes

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as a wetting agent in flavored mouth drops such as Ice Drops, helping to provide a spreading feeling to other ingredients like SD alcohol and mint flavor.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as an excipient in pharmaceutical applications to stabilize emulsions and suspensions.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in many brands of baby wipes.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is also used as wetting agent in rubber balers in the elastomer industry.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is a non-ionic detergent that is routinely used in biochemical and life science research.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is a surfactant and emulsifier used in cleaners and personal care products.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in personal care products

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as an emulsifier (mixing oil and water). 
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in cosmetic creams, cream deodorant, lotions, and sun lotion.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used as an emulsifier to combine oil and water.
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in room sprays

PEG (20) Sorbitan Monolaurate (Polysorbate 20) can also be used in a bath oils
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in cream preparations and shower gels / shampoos to aid stability and solubilisation.

PEG (20) Sorbitan Monolaurate (Polysorbate 20) is derived from sorbitol, a natural sugar alcohol
PEG (20) Sorbitan Monolaurate (Polysorbate 20) can be used as a emulsifier and detergent
PEG (20) Sorbitan Monolaurate (Polysorbate 20) is used in skincare and cosmetic formulations to improve the texture, feel, and scent of the product. 


SYNONYMS: 

PEG (20) Sorbitan Monolaurate
Polysorbate 20
Tween 20
9005-64-5
2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
1052273-76-3
9005-66-7
Sorbimacrogol laurate 300
2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate
2-(2-(3,4-Bis(2-hydroxyethoxy)tetrahydrofuran-2-yl)-2-(2-hydroxyethoxy)ethoxy)ethyl dodecanoate
2-[2-[3,4-bis(2-hydroxyethoxy)tetrahydrofuran-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
Alkest TW 20
Tween(R) 20
tween (R) 20
Tween 20 (TN)
Tween 40 (TN)
Tween 60 (TN)
POE (6) sorbitol monolaurate
POE(20) sorbitan monolaurate
POE (20) sorbitan monolaurate
2-(2-(3,4-bis(2-hydroxyethoxy)tetrahydrofuran-2-yl)-2-(2-hydroxyethoxy)ethoxy)ethyldodecanoate
2-{2-[3,4-Bis(2-hydroxyethoxy)tetrahydro-2-furanyl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate
3,6-Anhydro-1-O-[2-(dodecanoyloxy)ethyl]-2,4,5-tris-O-(2-hydroxyethyl)hexitol 
3,6-Anhydro-1-O-[2-(dodecanoyloxy)ethyl]-2,4,5-tris-O-(2-hydroxyethyl)hexitol 
3,6-Anhydro-1-O-[2-(dodecanoyloxy)éthyl]-2,4,5-tris-O-(2-hydroxyéthyl)hexitol
Hexitol, 3,6-anhydro-2,4,5-tris-O-(2-hydroxyethyl)-1-O-[2-[(1-oxododecyl)oxy]ethyl]- 
2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
9005-66-7 
9005-67-8 
Alkest TW 20
Dodecanoic acid 2-[2-[3,4-bis-(2-hydroxy-ethoxy)-tetrahydro-furan-2-yl]-2-(2-hydroxy-ethoxy)-ethoxy]-ethyl ester
E432
Ethoxylated Sorbitan monolaurate
MFCD00165986
PEG-80 Sorbitan laurate
POE(20) sorbitan monolaurate
Sorbimacrogol laurate 300
TWEEN 20
SORBITAN MONOLAURATE
capmul
PEG-80 SORBITAN LAURATE
Polisorbate 20- PS 20
POLYSORBATE 21
POLYOXYETHYLENE SORBITAN MONOLAUREATE
POLYETHYLENE GLYCOL SORBITAN MONOLAURATE
Tween 20
POLYOXYETHYLENE (20) SORBITAN MONOLAURATE
 

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