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PEG 200

CAS Number: 25322-68-3
MDL number: MFCD00081839
PubChem Substance ID: 24898829

Molecular Formula: C27H46O7


Polyethylene glycol is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. 
PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG is commonly expressed as H−(O−CH2−CH2)n−OH.

Identifiers
CAS Number: 25322-68-3 
ChEMBL    
ChEMBL1201478 
ChemSpider    
none
ECHA InfoCard: 100.105.546 
E number: E1521 (additional chemicals)
UNII    
3WJQ0SDW1A 
CompTox Dashboard (EPA)    
DTXSID4027862 

Applications of PEG 200:
PEG 200 in Antibody Drug Conjugate
In antibody drug conjugates (ADCs), the Linker between antibody and payload can significantly affect the potency, stability, selectivity, and DMPK of an antibody-drug conjugate. 
For example, ADC drug Zynlonta has incorporated several interesting linker components including the maleimide PEG8 with enzymatically cleavable linkers (Val-Ala) that connect the payload to the antibody.

Zynlonta, shown above, has maleimide-peg8 linkers between antibody and payload SG319 PBD dimer.

PEG 200 in Nanoparticle Drug Delivery
Lipid nanoparticle drug delivery has now become famous with the development of Moderna and Pfizer COVID-19 vaccines. 
Typically, the delivery system are composed of a high transition temperature phospholipid, a PEG lipid, and an ionizable cationic phospholipid. 
One specific example is DSPE-mPEG 2000, which is essential to producing the Pfizer COVID-19 vaccine. 
Another well-known PEGylated lipid is DMG-PEG 2000, which is used in the Moderna COVID-19 vaccine.
PEG 200 Lipids used in COVID-19 vaccines, Pfizer's DSPE-PEG 2000 shown on top and Moderna's DMG-PEG 2000 shown on bottom.

PEG 200 in Small Molecule Drug
Introduction of PEG linkers to small molecule drugs increases the drug's solubility and molecular weight. 
This may allow for an extended drug half-life in the body. Asclera (Polidocanol) is one example of a small molecule drug that incorporates an m-PEG9 entity which can be used as a local anesthetic in topical ointment form or injected to treat varicose veins.

Uses of PEG 200

Medical uses
Main articles: Macrogol and PEGylation
Pharmaceutical-grade PEG is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
PEG 200 is the basis of a number of laxatives (as MiraLax).[5] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy.
PEG 200 used in medicines for treating disimpaction and maintenance therapy for children with constipation.
When attached to various protein medications or drug carriers, polyethylene glycol of suitable length slows down their clearance from the blood.
The possibility that PEG could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.
An example of PEG hydrogels (see Biological uses section) in a therapeutic has been theorized by Ma et al. They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums.[10] The gel and encapsulated stem cells was to be injected to the site of disease and crosslinked to create the microenvironment required for the stem cells to function.
PEGylation of adenoviruses for gene therapy can help prevent adverse reactions due to pre-existing adenovirus immunity.
PEG 200 is used as an excipient in both the Moderna and Pfizer–BioNTech vaccines for SARS-CoV-2. Both RNA vaccines consist of messenger RNA, or mRNA, encased in a bubble of oily molecules called lipids. Proprietary lipid technology is used for each. In both vaccines, the bubbles are coated with a stabilizing molecule of polyethylene glycol.[medical citation needed] As of December 2020 there is some concern that PEG could trigger allergic reaction,[12] and in fact allergic reactions are the driver for both the United Kingdom and Canadian regulators to issue an advisory, noting that: two "individuals in the U.K... were treated and have recovered" from anaphylactic shock.[13][14] As of 18 December, the US CDC stated that in their jurisdiction six cases of "severe allergic reaction" had been recorded from more than 250,000 vaccinations, and of those six only one person had a "history of vaccination reactions".[15]

Chemical uses
The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG in the 1980s
Terra cotta warrior, showing traces of original color
Because PEG 200 is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.
Polyethylene glycol has a low toxicity and is used in a variety of products. 
PEG 200 is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.
Since PEG 200 is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). 
PEG 200 also is unlikely to have specific interactions with biological chemicals. 
These properties make PEG one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique.
Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
PEG 200 is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases. 

PEG 200 replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries. 
In addition, PEG 200 is used when working with green wood as a stabilizer, and to prevent shrinkage.
PEG has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China. 
These painted artifacts were created during the Qin Shi Huang (first emperor of China) era. 
Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air. 
PEG 200 would subsequently flake off in about four minutes. 
The German Bavarian State Conservation Office developed a PEG preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.
PEG 200 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
PEG 200 derivatives, such as narrow range ethoxylates, are used as surfactants.
PEG 200 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
PEG 200 is a component of the propellent used in UGM-133M Trident II Missiles, in service with the United States Navy.

Biological uses
PEG can be modified and crosslinked into a hydrogel and used to mimic the extracellular matrix (ECM) environment for cell encapsulation and studies.
An example study was done using PEG-diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages. 
This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.
PEG 200 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
PEG 200 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.

PEG 200 is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. César Milstein and Georges J. F. Köhler originated this technique, which they used for antibody production, winning a Nobel Prize in Physiology or Medicine in 1984.[5]
Polymer segments derived from PEG polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions.
In microbiology, PEG precipitation is used to concentrate viruses. PEG is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro.
Gene therapy vectors (such as viruses) can be PEG-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect. 
The size of the PEG polymer has been shown to be important, with larger polymers achieving the best immune protection.
PEG 200 is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo.
In blood banking, PEG is used as a potentiator to enhance detection of antigens and antibodies.
When working with phenol in a laboratory situation, PEG 300 can be used on phenol skin burns to deactivate any residual phenol.
In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.

Commercial uses
PEG 200 is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin).
PEG 200 is used in a number of toothpastes[5] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
PEG 200 is also under investigation for use in body armor, and in tattoos to monitor diabetes.[35][36]
In low-molecular-weight formulations (e.g. PEG 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads.
PEG 200 is also used as an anti-foaming agent in food and drinks[37] – its INS number is 1521[38] or E1521 in the EU.
Industrial uses
A nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.
Dimethyl ethers of PEG are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the syngas stream.

PEG 200 has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
PEG 200 is also used as a polymer host for solid polymer electrolytes. 
Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.
PEG 200 is injected into industrial processes to reduce foaming in separation equipment.
PEG 200 is used as a binder in the preparation of technical ceramics.
PEG 200 was used as an additive to silver halide photographic emulsions.
Entertainment uses
PEG 200 is used to extend the size and durability of very large soap bubbles.
PEG 200 is the main ingredient in many personal lubricants. (Not to be confused with propylene glycol.)
PEG 200 is the main ingredient in the paint (known as "fill") in paintballs.

PEG Linkers
PEG linkers are chemically functionalized polyethylene glycol (PEG) linkers. 
PEG linkers are particularly attractive as very powerful tools in scientific community for conjugation, drug discovery, nanoparticle drug delivery, chemical biology and biolabeling due to their aqueous solubility and non-immunogenicity.

There are two classes of PEG, monodispersed and poly-dispersed. 
A monodispersed PEG linker has an exact number of PEG units with a specific chemical structure and a precise molecular weight. 
Whereas a poly-dispersed PEG (also known as Polymer PEG or PolyPEG) is a polymer with an averaged molecular weight.

Example of Monodispersed PEG Linkers
Azido-PEG4-NHS ester is a popular monodisperse PEG linker with azide and NHS groups.
As a leading PEG supplier worldwide, BroadPharm has over 4,000 high purity PEG linkers in stock for overnight shipping. 
These products cover a wide range of functional groups, such as Azide, Amine, Alkyne, DBCO, TCO, NHS ester, Maleimide. 

PEG 200  is a clear, colorless liquid that is made from sugar cane waste so it is naturally derived and renewable. 
PEG 200 is completely soluble in water and has an average molecular weight of 190 - 210. 
PEGS 200 are another group of products with an incredibly long list of uses and applications from industrial uses to food and pharma, and everything in between.


Description of PEG 200
Catalogue Number: 807483
Product Information
CAS number: 25322-68-3
EC number: 500-038-2
Molar Mass: 190 - 210 g/mol
HS Code    3907 29 11
Quality Level: MQ200
Application: Polyethylene glycol 200 for synthesis. CAS No. 25322-68-3, EC Number 500-038-2.

Physicochemical Information of PEG 200
Boiling point: >200 °C (1013 hPa)
Density: 1.124 g/cm3 (20 °C)
Flash point: 138.6 °C
Ignition temperature: 350 °C DIN 51794
Melting Point: -50 °C
pH value: 5 - 7 (100 g/l, H₂O, 20 °C)
Vapor pressure: <0.1 hPa (20 °C)
Solubility: 70 g/l soluble

Toxicological Information of PEG 200
LD 50 oral: LD50 Rat 28000 mg/kg
LD 50 dermal: LD50 Rabbit > 20000 mg/kg

Safety Information according to GHS
RTECS: TQ3600000
Storage class: 10 - 13 Other liquids and solids
WGK: WGK 1 slightly hazardous to water

Disposal of PEG 200
Relatively unreactive organic reagents should be collected in container A. 
If halogenated, they should be collected in container B. For solid residues use container C.
Storage and Shipping Information
Storage    NoTempLimit

Specifications of PEG 200
Density: (d 20 °C/ 4 °C)    1.124 - 1.126
Hydroxyl value: 535 - 590
Average molecular: mass    190 - 210
Identity (IR): passes test

What Is Polyethylene Glycol Made From?
Our PEG-200 is made from bagasse, a fibrous byproduct of sugarcane production, commonly used as a biofuel. 
It features the same chemical composition and molecular weight as polyethylene glycol made from petroleum, and can be used in all the same applications with no noticeable difference. 
Bio-based PEG-200 is better for the environment and ultimately, a more responsible choice for your organization.

What Is Polyethylene Glycol Used For?
PEG-200 has a wide range of potential uses. 
PEG 200 is a defoaming agent, lubricant and viscosity modifier in many different products. 
PEG-200 is also used as a coating for fresh fruit, as a solvent in metal working fluids, as a binder and modifier in latex paints, and as a humectant in inks and abrasives. 
Specific industries that rely on PEG-200 include cosmetics, health and medicine, textiles and more.For a detailed list of potential applications, or for assistance determining whether or not our polyethylene glycol can be used for your product, contact Acme-Hardesty today.

Chemical Properties of PEG 200
Our polyethylene glycol 200 is a clear, colorless liquid at room temperature, sold in both drums and isotanks. 
Our NF-grade product has a shelf life of one year when stored in a dry, cool place according to MSDS recommendations.
The viscosity of our polyethylene glycol is 4.0–4.2 at 99 degrees C, cSt. 
It has a maximum water content of 0.20 percent and a maximum acidity of 0.05 percent. 
Under normal conditions, it is stable and nonreactive, but should be kept away from open flames, direct sunlight and strong oxidizers.

First aid measures of PEG 200
Description of first-aid measures
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. 
Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most). 
Consult doctor if feeling unwell.

Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Indication of any immediate medical attention and special treatment needed


Specifications of PEG 200
CAS Number: 25322-68-3
Grade: Technical
Appearance: liquid
Auto Ignition Temperature: 280 - 400 °C (536 - 752 °F)
Boiling Point: 200 °C (392 °F)
Color: Clear, Colorless
Density: 1.127 - 1.2 g/cm3 @ 20 - 25 °C (68 - 77 °F)
Dynamic Viscosity: 12.9 - 175 mPa.s
Evaporation Rate: < 0.01
Flash Point: 198.9 - 270 °C (390.0 - 518 °F)
Freezing Point: 4 - 8 °C (39 - 46 °F)
Kinematic Viscosity: 6.8 - 11.3 mm2/s @ 98.9 °C (210.0 °F)
Odor: alcohol-like, mild
Partition Coefficient: Pow: 2.25
pH: 4.5 - 7.5 @ 20 - 25 °C (68 - 77 °F)
Recommended Use: Industrial chemical
Relative Density: 1.127 - 1.13 @ 20 - 25 °C (68 - 77 °F) Reference Material: (water = 1)
Relative Vapor Density: > 1 @ 20 - 25 °C (68 - 77 °F)
Solubility in Water: soluble
Vapor Pressure: < 0.08 mmHg @ 20 - 25 °C (68 - 77 °F)

Description of PEG 200
PEG 200, commonly referred to as PEG 200, is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient and active ingredient. 
Due to its low toxicity it can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder. 
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. 

Specifications of PEG 200
CAS Max %: 1
pH: 4.5 to 7.5
Quantity: 2.5 L
Grade: Reagent
Packaging: Glass Bottle

TYPICAL SPECIFICATIONS of PEG 200
CLASS:    Glycols
MOLECULAR WEIGHT: 190 - 210
APPEARANCE: Colorless liquid
DENSITY: 1.124 g/cm3
BOILING POINT: >150 °C
MELTING POINT: -50 °C
FLASH POINT: 180 °C

Product Specification of PEG 200
Purity %: >99%
Usage/Application: Osmotic laxatives, Inactive substance for drugs, Surfactants
Grade Standard: Industrial Grade
CAS No: 25322-68-3
Chemical Formula: H(OCH2CH2)nOH
HS Code: 39072090
EC No.: 500-038-2
Physical State: Powder
Color: Colorless
Odour: Odorless
Molecular Weight: 3500 - 4500 g/mol
Density: 1.2 g/cm3
Melting Point: 53 - 58 DegreeC
Boiling Point: 200 DegreeC
Solubility in Water: 500 g/L
Acidity: 5 - 7
Refractive Index: n 20/D 1.467
Viscosity: 90.0 cSt at 25 DegreeC
Flash Point: 240 DegreeC
Ignition Temperature: >320 DegreeC DIN 51794
Minimum Order Quantity: 200 Kg

Available forms and nomenclature
PEG, PEO, and POE refer to an oligomer or polymer of ethylene oxide. 
The three names are chemically synonymous, but historically PEG is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. 
Because different applications require different polymer chain lengths, PEG has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass. 
PEG 200 are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.

PEG 200 are liquids or low-melting solids, depending on their molecular weights. 
While PEG 200 with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. 
Different forms of PEG are also available, depending on the initiator used for the polymerization process – the most common initiator is a monofunctional methyl ether PEG, or methoxypoly(ethylene glycol), abbreviated mPEG. 
Lower-molecular-weight PEGs are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. 
Very high-purity PEG has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray crystallography. 
Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10–1000 fold that of polydisperse PEG.

PEGs are also available with different geometries.
Branched PEGs have three to ten PEG chains emanating from a central core group.
Star PEGs have 10 to 100 PEG chains emanating from a central core group.
Comb PEGs have multiple PEG chains normally grafted onto a polymer backbone.
The numbers that are often included in the names of PEGs indicate their average molecular weights (e.g. a PEG with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 400). Most PEGs include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index (ĐM). Mw and Mn can be measured by mass spectrometry.

PEGylation is the act of covalently coupling a PEG structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEGylated protein. 
PEGylated interferon alfa-2a or alfa-2b are commonly used injectable treatments for hepatitis C infection.

PEG 200 is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. 
PEG 200 is coupled to hydrophobic molecules to produce non-ionic surfactants.
PEGs 200potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane. 
PEG 200 and its ethers are nephrotoxic if applied to damaged skin.

PEG and related polymers (PEG phospholipid constructs) are often sonicated when used in biomedical applications. 
However, as reported by Murali et al., PEG is very sensitive to sonolytic degradation and PEG degradation products can be toxic to mammalian cells. 
PEG 200 is, thus, imperative to assess potential PEG degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.

PEG 200 are used commercially in numerous applications, including foods, in cosmetics, in pharmaceutics, in biomedicine, as dispersing agents, as solvents, in ointments, in suppository bases, as tablet excipients, and as laxatives. 
Some specific groups are lauromacrogols, nonoxynols, octoxynols, and poloxamers.

Macrogol, MiraLax, GoLytely, Colace used as a laxative, is a form of polyethylene glycol. 
The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000).

Description and Uses of PEG 200
Polyethylene glycol (C2nH4n+2On+1) is a polyether compound with many applications from industrial manufacturing to medicine.
Applications of polyethylene glycol 200 inlcude use as a humectant, solvent, lubricant and a mold release agent.

Uses:
Lubricants and greases
Plastics
Rubber
Soaps and detergents
Textiles
Personal care

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance
COLOURLESS VISCOUS SLIGHTLY HYGROSCOPIC LIQUID. 

Formula: HO(C2H4O)nH
Molecular mass: 200-600
Boiling point: 250°C
Melting point: softening point
See Notes.
Relative density (water = 1): 1.13
Solubility in water at 20°C: very good
Vapour pressure, Pa at 20°C: <10
Flash point: 171-235°C
Auto-ignition temperature: ~360°C  


What Is PEG 200?
PEG 200 are polymers of ethylene glycol. 
The number in the name represents the average number of ethylene glycol units. 
PEG 200 associated with the number stands for 1000, so PEG-25M is has an average of 25,000 units of ethylene glycol. 
The polyethylene glycol polymers are used in a wide variety of products including bath products, shaving products, skin care products, makeup, skin cleansing products, shampoo, hair conditioners and deodorants.

Why is PEG 200 used in cosmetics and personal care products?
The following functions have been reported for these ingredients.
Anticaking agent 
Binder 
Emulsion stabilizer 
Humectant 
Plasticizer 
Solvent 
Viscosity decreasing agent 
Viscosity increasing agent –

SPECIFICATIONS
CAS Number: 56-81-5
Appearance: Liquid
Flash Point: 160°C (320°F) 
Boiling Point: 182°C (360°F) at 27 hPa (20 mmHg)
Color :Clear
Relative Density: 1.25 g/mL
Formula: C3H8O3
Molecular Weight: 92.09 g/mol
Vapor Density : 1.25 g/mL

Computed Properties    
Molecular Weight: 482.6    
XLogP3-AA: 4.5    
Hydrogen Bond Donor Count: 0    
Hydrogen Bond Acceptor Count: 7    
Rotatable Bond Count: 24    
Exact Mass: 482.32435380    
Monoisotopic Mass: 482.32435380    
Topological Polar Surface Area    : 104 Ų    
Heavy Atom Count: 34    
Formal Charge: 0    
Complexity: 575    
Isotope Atom Count: 0    
Defined Atom Stereocenter Count: 0    
Undefined Atom Stereocenter Count: 2    
Defined Bond Stereocenter Count: 0    
Undefined Bond Stereocenter Count: 0    
Covalently-Bonded Unit Count: 1    
Compound Is Canonicalized: Yes    

Polyethylene glycol with molecular weight of 200, HO-(CH2CH20)n-H. 
Name : Polyethylene Glycol
CAS number : 25322-68-3
Type : Oxyalkylene Polymer
Adhesives: Lubricants
Agriculture: Mold Release Agent
Chemical Intermediates: Plasticizer
pH-5% in aq @ 25°C
Color: Water
Acidity, as Acetic Acid
Viscosity @ 210 °F (99°C)
Physical State
Odour
Solubility in Water @ 20 °C: 190 - 210

Properties and application of PEG 200
Polyethylene glycol series can be used as solvent, o/w emulsifying agent, stabilize;
PEG 200 are used as excipient in medical industry; as coating agent in paper-amking industry; as additive in rubber industry;
Polyethylene glycol series product can be used as ester type surface active agent;
PEG-200 can be used as medium in organic synthesis;
PEG-200, are used as basis of medical and cosmetics; lubrication agent in rubber and textile industry;

Packaging and storage
This series product is non-toxic chemical products; store in dry and ventilated place;
Expiration date: 2 year

Description
PEG 200 (Polyethylene Glycol 200) has a wide range of applications. 
PEG 200 is used in a variety of products as a defoaming agent, lubricant, and viscosity modifier. 
PEG-200 is also utilized as a fruit coating, a solvent in metalworking fluids, a latex paint binder and modifier, and a humectant in inks and abrasives. 
PEG-200 is used in a variety of industries, including cosmetics, healthcare, textiles, and more. 
At normal temperature, our polyethylene glycol 200 is a transparent, colorless liquid.

PEG 200 from DIYChemicals has a wide range of applications.
SUGGESTED USE: Defoaming agent, lubricant, and viscosity modifier in cosmetic, food, and industrial goods.
At room temperature, a clear, colorless liquid is stored.
Made in the United States, with a 100% satisfaction guarantee.

Polyethylene Glycol Specification
POLY ETHYLENE GLYCOL is produced by the reaction of ethylene oxide with either ethylene glycol or water. 
SVC offers a wide range of Polyethylene glycol in the brand name of PEG with average molecular weight of 200, 300, 400, 600, 1500, 3350, 4000, 6000 and 10000. 
The range has a gradual variation in properties which has enabled them to find their ways into wide variety of industries - either alone or in blends, in aqueous solution and as intermediates in the production of surfactants, lubricants and plasticizers. 
SVC's PEG conforms to the pharmacopoeia specification i.e. USP/NF, BP/Eph and IP.

Polyethylene Glycols are series of low to medium molecular weight polyether idols having primary hydroxyl group at each and all Polyethylene Glycols are completely soluble in water, very low toxicity, quite blend, non-irritating and possess wide compatibility good solvent action, good stability and good lubricity, etc. 
This unusual combination of properties has enabled them to find a very wide range of commercial application in field of pharmaceuticals, Cosmetics, Paper, Textiles, Rubber, Ceramics, Wood processing, Packing and manufacturing of surfactant, dispersant resin and plastics etc.

Polyethylene Glycols derivatives like mono and diesters of fatty acids are widely used as a surface active agent, emulsifiers and lubricants.
Glycol Polyethylene 200 or PEG 200 is most popular product is used in various industries like Textile, Lather, Pharmaceuticals, etc. 
Some special molecular weight of Glycol Polyethylene like PEG 200 & PEG 4000 are widely used in the industries.
A letters numbers identifies each of the Polyethylene Glycols and it’s also indicates the average molecular weight.

Polyethylene Glycol (PEG) Surface
Polyethylene glycol (PEG) is a polyether compound that consists of repeating units of ethylene oxide. 
PEG 200 is a safe compound that is used in a wide variety of application including food additives, as an excipient in pharmaceutical products, and as a stealth coating in biomedical applications to reduce non-specific binding and to evade the body’s immune system. 
The PEG 200 surface is the most stable of our surfaces in buffers containing high salt concentrations found in culture media or other high ionic buffers. 
The PEG 200 surface functionality disperses very well in water and protic solvents, increasing compatibility in biological systems. 
The methoxy 200 PEG surface has a slightly negative to neutral surface charge which is advantageous for in-vivo or in-vitro applications.


Methoxy PEG sulfhydryl
The methoxy terminated PEG is available on both gold and silver nanoparticles increasing particle stability in a wide range of solvents. 

PEG-200 Hydrogenated Glyceryl Palmate at a Glance
Thickener used in hair and skin care products
Also an emulsifier
Ruled safe as used in cosmetics
Appears as a slightly yellowish liquid in its raw form
PEG-200 Hydrogenated Glyceryl Palmate Description
PEG-200 hydrogenated glyceryl palmate is a thickener used in hair and skin care products, especially in formulas that are difficult to thicken. It is also an emulsifier and can help stabilize formulations by enhancing the solubility of key ingredients.

PEG-200 hydrogenated glyceryl palmate has been ruled safe as used in cosmetics. 
In PEG 200raw form, it is a slightly yellowish liquid. 
PEG 200 is often combined with emollient and emulsifying cleansing agent PEG-& glyceryl cocoate.

Product Details of PEG 200
CAS No: 25322-68-3
Chemical Name: Polyethylene Glycol
Medicine Name: Glycol
Physical Form: Liquid
Purity(%): 99%
Grade: Industrial Grade
Storage: Room Temperature
Solubility: 100%
Sample Available: Yes


Chemical composition of ethylene oxide condensates
Type nonionic
CAS 25322-68-3
Specification PEG200,300,400,600,800,1000,1500,2000,3000,4000,6000, 8000 (special specifications can be developed on behalf of processing)

Properties and Application
PEG 200 excipient used in the pharmaceutical industry suppositories, prepared as a paste; used as a coating agent for paper industry, increase paper gloss and smoothness; in the rubber industry as an additive to increase the lubrication of rubber products and plasticity, reduce processing power consumption and extend the life of rubber products.
PEG 200 can be used as raw material ester surfactant.
PEG-200 can be used as organic synthesis of medium and higher requirements for heat carrier, is used as a humectant in daily chemical industry, inorganic salt solubilizers, viscosity modifiers; used as a softener in the textile industry, anti- static agent; paper and used as a wetting agent in the pesticide industry.

Properties and applications
Product advantages:
excellent solvent for active substances,
strong hygroscopic properties,
agent with anti-electrostatic and lubricating properties,
the best alkali resistance among PEGs available in our offer,
low viscosity,
low pour point,
high solubility in water,
approved by the FDA for use as an indirect food additive.

Applications:
self-curing concretes,
cement mortars,
metalworking,
industrial cleaning,
cosmetics,
accessories for packaging,
cleaning of reactors in the polyurethane industry,
raw material for the synthesis of esters.

APPEARANCE
Slightly yellowish liquid

FUNCTION
PEG 200 Is a very effective thickening agent. 
PEG 200 is especially suitable for difficult to thicken formulations. 
PEG 200 is naturally derived and is used as a mild additive which is recommended for baby products and for other mild hair/skin cleansing formulations for delicate skin. 
Also has refatting properties.

STORAGE
Keep container tightly closed and away from oxidizing materials.

Synonyms of PEG 200    
Polyethylene glycol 200 di-2-ethylhexoate
Hydrogenated Glyceryl Palmate
REWODERM LI 520
Palmitoyl-rac-glycerol
Glycerol 1-monopalmitate
V2999
2,3-dihydroxypropyl hexadecanoate
1-Monopalmitin
Palmitin, 1-mono-
1-Palmitoylglycerol
Hexadecanoic acid, 2,3-dihydroxypropyl ester
Glyceryl palmitate
2,3-Dihydroxypropyl palmitate
 

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