Quick Search
PEG 400 Monostearat is known for its ability to enhance the solubility of poorly soluble substances in water and is often used to create products with a lighter texture.
PEG 400 Monostearat can be found in a variety of personal care items such as creams, lotions, cleansers, and makeup products.
PEG 400 Monostearat is the polyethylene glycol ester of stearic acid.
CAS Number: 9004-99-3
Molecular Formula: C34H70O9
Molecular Weight: 622.91
EINECS Number: 618-405-1
PEG 400 Monostearat,E-431,INS NO.431,INS-431,POLYETHYLENE GLYCOL (40 DP) MONOSTEARATE,POLYOXYETHYLENE(40)MONOSTEARATE,POLYOXYL 40 MONOSTEARATE,POLYOXYL(40)STEARATE,2-Hydroxyethyl stearate, Glycol stearate,9004-99-3,2-Hydroxyethyl octadecanoate
PEG 400 Monostearat helps to stabilize emulsions, preventing the separation of oil and water components in a formulation.
PEG 400 Monostearat, is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient.
Due to its low toxicity PEG 400 Monostearat can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder.
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
PEG 400 Monostearat has a low vapour pressure and is stable to heat, acids and bases.
PEG 400 Monostearat is a thermoplastic resin with good compatibility with other resins.
PEG 400 Monostearat does not interact with many chemicals.
PEG 400 Monostearat has good hygroscopicity, lubricity and bonding properties.
PEG 400 Monostearat is white granular.
PEG 400 Monostearat is a nonionic mild fatty acid ester used primarily as a surfactant.
PEG 400 Monostearat is a mixture of the monoand diesters of stearic acid and mixed polyoxyethylene diols having an average polymer length of 7.5 oxyethylene units.
PEG 400 Monostearat is a polymer with the chemical formula HO(CH2CH2O)nH.
PEG 400 Monostearat , PEG for short , also (obsolete) polyethylene glycol and in pharmaceuticals also macrogol , is a - depending on the chain length - liquid or solid, water-soluble and non-toxic polymer with the general molecular formula C 2n H 4n+2 O n+1 .
Because of these properties, PEG 400 Monostearat is used in medicine , as an active ingredient carrier in pharmaceuticals , in industrial applications, in cell biology research and in cosmetic products.
PEG 400 Monostearat has different properties depending on the chain length and the resulting molar mass.
PEG 400 Monostearat is properties vary according to its molecular weight, from a colourless and odourless viscous liquid to a waxy solid.
PEG 400 Monostearat is a liquid at room temperature with a molecular weight of 200 to 600, and gradually becomes a semi-solid with a molecular weight above 600, with different properties depending on the average molecular weight.
As the molecular weight increases, PEG 400 Monostearat is hygroscopic capacity decreases accordingly.
PEG 400 Monostearat is resistant to bacterial erosion and has weak hygroscopicity in the atmosphere.
PEG 400 Monostearat is a polyethylene glycol (PEG) derivative of stearic acid.
PEG 400 Monostearats are a family of compounds that are formed by polymerizing ethylene oxide, and they are often used in the cosmetic and pharmaceutical industries as emollients, emulsifiers, and solubilizing agents.
PEG 400 Monostearat is soluble in water, ethanol and many other organic solvents.
PEG 400 Monostearat also imparts better spreading characteristics to creams and lotions and can be used as an emulsifier, lubricating agent and dispersant.
PEG 400 Monostearat is primarily employed as an emulsifier, helping to create stable mixtures of oil and water in cosmetic and personal care products.
Emulsifiers play a crucial role in maintaining the integrity of these formulations, ensuring that water and oil-based ingredients remain evenly distributed.
PEG 400 Monostearat contributes to the texture and consistency of a product, providing a smooth and desirable feel.
This is particularly important in skincare and cosmetic products where consumers often expect a certain texture and ease of application.
PEG 400 Monostearat acts as a solubilizing agent, enhancing the solubility of different ingredients in water.
This property is valuable for incorporating both water-soluble and oil-soluble components into a single formulation.
PEG 400 Monostearat aids in the spreadability of products on the skin or hair, allowing for easy application and absorption.
PEG 400 Monostearat is often found in cleansing formulations, such as facial cleansers and body washes, where it helps to emulsify and remove dirt, oils, and other impurities.
In hair care products like shampoos and conditioners, PEG 400 Monostearat can contribute to the emulsion stability and overall performance of the product.
PEG 400 Monostearat is a saturated fatty acid found in various animal and vegetable fats.
When combined with polyethylene glycol to form PEG-200 Stearate, it serves as an emulsifying agent.
Emulsifiers help stabilize and maintain the consistency of mixtures containing both water and oil components.
Polyethylene glycol is produced using anionic polymerization of ethylene oxide.
PEG 400 Monostearat with a molecular weight of up to 3,000,000 g/mol can be produced using catalysts such as alkaline earth metal oxides or carbonates.
Alternatively, cationic polymerization is also possible, but this plays no role technically.
PEG 400 Monostearat Market size is expected to develop revenue and exponential market growth at a remarkable CAGR during the forecast period from 2023–2030.
PEG 400 Monostearat is listed as particularly applicable for hand and body lotions and creams.
PEG 400 Monostearat is an emulsifier.
PEG 400 Monostearat is part of a family of PEG-stearate compounds, with the number indicating the average molecular weight of the polyethylene glycol chain.
In this case, PEG 400 Monostearat has a polyethylene glycol chain with an average molecular weight of 200.
The stearate portion of the molecule is derived from stearic acid, a long-chain fatty acid.
PEG 400 Monostearat is primary function is as an emulsifying agent, helping to stabilize and blend water and oil-based ingredients in formulations.
The growth of the market can be attributed to the increasing demand for PEG 400 Monostearat owning to the Cosmetic, Skin Care Products, Hair Care Products, Other Applications across the global level.
The report provides insights regarding the lucrative opportunities in the PEG 400 Monostearat at the country level.
They are well tolerated by the skin and are not microbiologically sensitive, so that in general it is not necessary to add any preservatives.
PEG 400 Monostearat report represents gathered information about a market within an industry or various industries.
The PEG 400 Monostearat Market report includes analysis in terms of both quantitative and qualitative data with a forecast period of the report extending from 2023 to 2030.
The report is prepared to take into consideration various factors such as Product pricing, Product or services penetration at both country and regional levels, Country GDP, market dynamics of parent market & child markets, End application industries, major players, consumer buying behavior, economic, political, social scenarios of countries, many others.
The report is divided into various segments to offer a detailed analysis of the market from every possible aspect of the market.
The overall report focuses on primary sections such as – market segments, market outlook, competitive landscape, and company profiles.
PEG 400 Monostearat can contribute to the smoothness and spreadability of a product.
PEG 400 Monostearat helps improve the overall sensory experience of applying creams and lotions.
Due to its emulsifying properties, products containing PEG 400 Monostearat may enhance hydration by combining water and oil components effectively.
In cosmetics, PEG 400 Monostearat may be used in creams, lotions, and other skincare products to improve texture, stability, and the overall performance of the formulation.
PEG 400 Monostearat is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.
PEG 400 Monostearats are poly condensation products of ethylene glycol, or polymerisation products of ethylene oxide.
The number added to the name refers to the mean number of ethylene oxide units in the PEG 400 Monostearat.
The consistency of the PEG derivatives is increasingly solid with a growing degree of polymerisation.
PEG 400 Monostearats with a mean molar mass of up to 600 g/mol are liquid, up to 1,000 g/mol wax-like and from 4,000 g/mol solid wax-like substances.
By mixing solid and liquid components, products of a creamy consistency are obtained which are used as water-free and water rinse-off bases.
With growing molar mass water solubility and hygroscopicity (ability to absorb moisture) of the polyethylene glycols decrease.
PEG 400 Monostearats and their derivates are preferentially used in cosmetic products since they have a broad spectrum of viscosity and solubility properties and have a very good skin tolerance.
As water soluble, non-greasy substances PEG 400 Monostearats are suitable for many cosmetic purposes.
Pegosperse(R) 1500 MS is a mixture of polyethylene glycol esters. It is compatible with lipophilic compounds due to a higher free fatty acid content. Suggested applications: cosmetic formulations, lubricants.
Melting point: 47 °C
Flash point: 39 °C
storage temp.: 2-8°C
Water Solubility: Soluble in water
solubility: Chloroform (Slighty), Methanol (Slightly)
form: powder to lump
color: White to Almost white
Odor: at 100.00?%. mild fatty
Hydrophilic-Lipophilic Balance (HLB): 18.8
LogP: 7.629 (est)
PEG 400 Monostearat is versatility and ability to improve the stability of emulsions make it a popular choice for formulators.
PEG 400 Monostearat reduces vinblastine sulfate efllux.
The cytotoxicity of vinblastine to K562/ADR cells is significantly enhanced when the cells are cotreated with 100 or 150 μg/mL PEG 400 Monostearat.
PEG 400 Monostearat is a neutral surfactant.
PEG 400 Monostearat is a non-ionic surfactant, which is permitted for use as the E number food additive E431.
PEG 400 Monostearat is an octadecanoate ester composed of repeating 8-40 ethyleneoxy units.
PEG 400 Monostearat is an ingredient used in cosmetics.
PEG 400 Monostearat is an ingredient used in beauty products primarily as a surfactant and emulsifier.
PEG 400 Monostearat is a mixture of the monoand diesters of stearic acid.
PEG 400 Monostearat is mixed polyoxyethylene diols having an average polymer length of 7.5 oxyethylene units.
Emulsions that contain PEG-200 Stearate tend to have improved stability over time.
This stability is crucial for maintaining the integrity of the product and preventing phase separation (separation of water and oil phases).
PEG 400 Monostearat acts as a surfactant, which means it can reduce the surface tension between different phases in a formulation.
This property is valuable in achieving a homogenous blend of ingredients.
PEG 400 Monostearat can enhance the solubility of certain ingredients in formulations.
PEG 400 Monostearat, like other PEG derivatives, has a specific HLB value.
This value determines the balance between its hydrophilic (water-attracting) and lipophilic (oil-attracting) properties.
The PEG 400 Monostearat value is crucial for formulators when selecting emulsifiers to achieve the desired characteristics in a product.
Blending different emulsifiers allows formulators to fine-tune the properties of a product.
PEG 400 Monostearat Stearate can contribute to the viscosity or thickness of a product.
This can be advantageous in creating creams and lotions with a desirable consistency for easy application and spreadability.
In some formulations, PEG 400 Monostearat may play a role in enhancing the absorption or penetration of other active ingredients into the skin.
During the manufacturing process, attention is given to controlling the molecular weight and purity of PEG 400 Monostearat to meet quality standards.
This includes measures to minimize impurities that could potentially be present, such as 1,4-dioxane.
PEG 400 Monostearats enables a significant reduction of the active surfactant level in standard cleansing formulations.
In addition, the extraordinary efficiency and high flexibility of PEG 400 Monostearat facilitate the thickening of challenging surfactant systems, such as sulfate-free formulas, effectively supporting the trend for milder cleansing in personal care.
PEG 400 Monostearat is a mixture of polyethylene glycol esters.
PEG 400 Monostearat is compatible with lipophilic compounds due to a higher free fatty acid content.
Suggested applications: cosmetic formulations, lubricants.
PEG 400 Monostearat is a high molecular weight, high HLB surface active agent suggested for use in cosmetic formulations (emulsifier, viscosity modifier) and in lubricants (emulsifier).
The larger the surfactantn of PEG 400 Monostearat is a neutral, the lower the saponification value (mgKOH/g) and the larger the HLB value.
The pH of 1% aqueous solution is between 5.0 and 7.5, in which n≤ 8 is diffusive in water and has good flexibility and lubricity.
PEG 400 Monostearat can be used as a softener for fiber processing and has good antistatic and lubricity.
PEG 400 Monostearat is use softener during fabric weaving to reduce breakage and improve fabric feel.
As an emulsifier in cosmetics, the general dosage is 1-3%.
PEG 400 Monostearat can also be used as a co-emulsifier for the emulsification of paraffin wax.
PEG 400 Monostearat is used as emulsifier in lubricating oil production.
The 100% active, preservative-free solid is clearly soluble in water and processable at room temperature.
PEG 400 Monostearat is a non-ionic surfactant, which is permitted for use as the E number food additive E431.
This property is important in skincare products where effective delivery of active compounds is desired.
PEG 400 Monostearat is used as softener and antistatic agent in textile industry, emulsifier and solubilizer in cosmetics, food and pharmaceutical industry, and can also be used for emulsification of cardboard, construction board and waterproof wax.
As an emulsifier, solubilizer, ointment matrix in the pharmaceutical industry, as an emulsifier and detergent in the cosmetics industry, as a softener and antistatic agent in the textile industry, and as an emulsifying additive in the food industry.
PEG 400 Monostearat is a neutral surfactant.
PEG 400 Monostearat itself is generally regarded as safe for use in cosmetics, the overall safety of a product also depends on the specific formulation and the concentration of ingredients.
Regulatory bodies in different countries, such as the U.S. Food and Drug Administration (FDA) and the European Commission, set guidelines for the use of cosmetic ingredients to ensure product safety.
PEG 400 Monostearat is considered safe for use in cosmetics, individuals with very sensitive skin may want to be cautious and patch-test products containing this ingredient, as with any new skincare or cosmetic product.
PEG 400 Monostearats are known for their biodegradability, which is a positive environmental characteristic.
However, the overall environmental impact of a product depends on its complete formulation, including other ingredients and packaging.
PEG 400 Monostearat has been recommended as an additive to the radiolabelled 7H12 Middlebrook TB media and as such has been shown to enhance growth of mycobacteria in the radiometric BACTEC rapid culture system.
PEG 400 Monostearat produces the greatest enhancement in growth and reduction in the time taken to detect growth for M. tuberculosis and polyoxyethylene (30) stearate and polyoxyethylene (JL) stearate for species of mycobacteria other than M. tuberculosis.
PEG 400 Monostearat inhibits P-gp mediated efflux in a concentration dependent manner mainly by modulating substrate-stimulated P-gp ATPase activity.
PEG 400 Monostearat is commonly used in a variety of cosmetic and personal care products, including creams, lotions, sunscreens, and other skincare formulations.
Uses Of PEG 400 Monostearat:
PEG 400 Monostearat lipid technology is used for each.
PEG 400 Monostearat is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
PEG 400 Monostearat is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases.
PEG 400 Monostearat replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, PEG 400 Monostearat is used when working with green wood as a stabilizer, and to prevent shrinkage.
PEG 400 Monostearat has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.
These painted artifacts were created during the Qin Shi Huang (first emperor of China) era.
Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air.
The paint would subsequently flake off in about four minutes.
The German Bavarian State Conservation Office developed a PEG 400 Monostearat preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.
PEG 400 Monostearat is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
PEG 400 Monostearat derivatives, such as narrow range ethoxylates, are used as surfactants.
PEG 400 Monostearat can be used as a medium for organic synthesis and a heat carrier with high requirements.
PEG 400 Monostearat is used as a humectant, inorganic salt solubilizer and viscosity adjuster in the daily chemical industry; as a softener and antistatic agent in the textile industry; as a wetting agent in the paper and pesticide industry.
PEG 400 Monostearat is most suitable for softgels.
PEG 400 Monostearat is a liquid, it has a wide range of compatibility with various solvents and is a good solvent and solubiliser, and is widely used in liquid formulations, such as oral liquids and eye drops.
PEG 400 Monostearat has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
PEG 400 Monostearat is a component of the propellent used in UGM-133M Trident II Missiles, in service with the United States Navy.
An example study was done using PEG 400 Monostearat-diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages.
This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.
PEG 400 Monostearat is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
Although polyethylene glycol is considered biologically inert, it can form non-covalent complexes with monovalent cations such as Na+, K+, Rb+, and Cs+, affecting equilibrium constants of biochemical reactions.
PEG 400 Monostearat is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.
PEG 400 Monostearat is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas.
In microbiology, PEG 400 Monostearat precipitation is used to concentrate viruses.
PEG 400 Monostearat is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro.
Gene therapy vectors (such as viruses) can be PEG-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.
PEG 400 Monostearat is the material of choice when vegetable oils are not suitable as a carrier for active ingredients.
PEG 400 Monostearat a nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.
Dimethyl ethers of PEG 400 Monostearat are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the syngas stream.
PEG 400 Monostearat has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
PEG 400 Monostearat is also used as a polymer host for solid polymer electrolytes.
PEG 400 Monostearat is also used as an anti-foaming agent in food and drinks[32] – its INS number is 1521[33] or E1521 in the EU.
PEG 400 Monostearat has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.
PEG 400 Monostearat has also been used in a study to investigate its effects on multidrug resistance (MDR).
PEG 400 Monostearat has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.
PEG 400 Monostearat has also been used in a study to investigate its effects on multidrug resistance (MDR).
PEG 400 Monostearat serves as an emulsifying agent, helping to blend water and oil-based ingredients in formulations.
This is particularly important in creams, lotions, and other skincare products where a stable and uniform texture is desired.
PEG 400 Monostearat contributes to the smoothness and spreadability of cosmetic and personal care products.
This enhances the sensory experience of applying creams, lotions, and other formulations.
PEG 400 Monostearat improves the stability of emulsions over time, preventing the separation of water and oil phases.
This is crucial for maintaining the integrity and appearance of the product throughout its shelf life.
Due to its emulsifying properties, products containing PEG 400 Monostearat can enhance hydration by effectively combining water and oil components.
This is beneficial for moisturizing and hydrating formulations.
PEG 400 Monostearat may be found in some cleansing products, contributing to the formulation's ability to remove dirt and oil from the skin.
PEG 400 Monostearat can act as a thickening agent, helping to give certain formulations a desired viscosity.
This is particularly useful in creating creams and lotions with a consistent and pleasant texture.
Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG 400 Monostearat, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.
PEG 400 Monostearat is injected into industrial processes to reduce foaming in separation equipment.
PEG 400 Monostearat is used as a binder in the preparation of technical ceramics.
PEG 400 Monostearat can improve the solubility of certain ingredients in formulations, making it easier to incorporate a diverse range of components into a product.
PEG 400 Monostearat may enhance the absorption or penetration of other active ingredients into the skin.
This is particularly relevant in skincare products where the effective delivery of active compounds is important.
PEG 400 Monostearat is sometimes included in hair care products such as conditioners and styling products.
PEG 400 Monostearat is emulsifying properties can contribute to the even distribution of conditioning agents, improving the overall performance of the product.
PEG 400 Monostearat may be used to help disperse UV filters evenly, improving the product's effectiveness and providing a smoother application.
PEG 400 Monostearat is utilized in a wide range of cosmetic formulations, including foundations, concealers, and color cosmetics.
PEG 400 Monostearat is emulsifying and stabilizing properties contribute to the uniform blending of pigments and other ingredients.
PEG 400 Monostearat can be found in pharmaceutical ointments and topical medications.
PEG 400 Monostearat is emulsifying properties aid in the formulation of stable and easy-to-apply medicinal creams.
In certain wound care formulations, PEG 400 Monostearat may be used to improve the spreadability of the product and facilitate the application of active ingredients.
PEG 400 Monostearat is often chosen for formulations that include both water-soluble and oil-soluble active ingredients, as it helps create a compatible and effective product.
In some formulations, PEG 400 Monostearat can be used as an alternative to petroleum jelly.
PEG 400 Monostearat provides a similar smooth texture and emollient properties without the heavy feel associated with petroleum-based products.
PEG 400 Monostearat was used as an additive to silver halide photographic emulsions.
PEG 400 Monostearat is the basis of many skin creams (as cetomacrogol) and personal lubricants.
PEG 400 Monostearat is used in a number of toothpastes[5] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
PEG 400 Monostearat is also under investigation for use in body armor, and in tattoos to monitor diabetes.
PEG 400 Monostearat is compatible with lipophilic compounds due to a higher free fatty acid content.
Suggested applications: cosmetic formulations, lubricants.
PEG 400 Monostearat is used as a base or lubricant and softener in the pharmaceutical, textile and cosmetic industries; used as a dispersant in the paint industry to improve the water dispersibility and flexibility of resins, with a dosage of 10-30%; used to improve the solubility of dyestuffs and reduce their volatility in printing ink, especially in wax paper and printing ink, also used to adjust the consistency of ink in biros ink.
PEG 400 Monostearat is used as metal processing casting agent, lubricant and cutting fluid for metal drawing, stamping or forming, grinding cooling lubricating polishing agent, welding agent, etc.; used as lubricant in paper industry, etc., also used as hot melt adhesive to increase fast rewetting ability.
PEG 400 Monostearat good coating material, hydrophilic polishing material, film and capsule material, plasticizer, lubricant and drip matrix for the preparation of tablets, pills, capsules, microcapsules, etc.
PEG 400 Monostearat is widely used as an emulsifying agent in cosmetic formulations.
PEG 400 Monostearat helps to create stable emulsions by dispersing and stabilizing the oil and water phases in a product.
This is particularly important in creams, lotions, and other emulsion-based formulations.
PEG 400 Monostearat can improve the wetting and spreading properties of cosmetic products.
PEG 400 Monostearat helps to break down the surface tension between different ingredients, facilitating their even distribution.
PEG 400 Monostearat contributes to the texture of cosmetic products, providing a smooth and creamy consistency.
PEG 400 Monostearat enhances the feel and application of creams, lotions, and other skincare formulations.
PEG 400 Monostearat acts as a solubilizing agent, aiding in the incorporation of both water-soluble and oil-soluble ingredients into a single formulation.
This is particularly useful in creating well-blended products.
PEG 400 Monostearat is often found in cleansers, including facial cleansers and body washes.
PEG 400 Monostearat is emulsifying properties help in the effective removal of dirt, oils, and impurities from the skin.
PEG 400 Monostearat is used in hair care products such as shampoos and conditioners to contribute to the emulsion stability and texture.
PEG 400 Monostearat can also help in the even distribution of active ingredients on the hair.
PEG 400 Monostearat may be included in the formulation of various makeup products, such as foundations, creams, and lotions, to improve texture, stability, and application.
PEG 400 Monostearat is found in a variety of topical formulations, including moisturizers, sunscreens, and serums, where its emulsifying and solubilizing properties are beneficial.
PEG 400 Monostearat is used as a finishing agent in the paper industry to increase the gloss and smoothness of paper; as an additive in the rubber industry to increase the lubricity and plasticity of rubber products, reduce the power consumption during processing and extend the service life of rubber products.
PEG 400 Monostearat is also used as a dispersant in the rubber industry to promote vulcanisation and as a dispersant for carbon black filling materials.
PEG 400 Monostearat is an emulsifier and antifoaming agent used in processed foods, fruit jellies, and sauces.
PEG 400 Monostearat is used as a surfactant, emulsifier (cosmetics, pharmaceuticals, textile finishes, defoamers, and baked goods), dye assistant, lubricant, and antistatic agent; Also used in dentifrice compositions and to make creams, lotions, ointments, and pharmaceutical preparations.
PEG 400 Monostearat is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
PEG 400 Monostearat is the basis of a number of laxatives (as MiraLax, RestoraLAX, etc.).
Whole bowel irrigation with PEG 400 Monostearat and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation.
Macrogol (with brand names such as Laxido, GoLytely and Miralax) is the generic name for PEG 400 Monostearat used as a laxative.
The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000).
The possibility that PEG could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.
An example of PEG 400 Monostearats in a therapeutic has been theorized by Ma et al.
They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums.
Safety Profile Of PEG 400 Monostearat:
Some individuals may be sensitive or allergic to certain PEG derivatives, including PEG 400 Monostearat.
This is a consideration for individuals who prefer products with minimal ingredient absorption.
Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG, hypersensitive reactions to PEG 400 Monostearat are an increasing concern.
Very slightly toxic by ingestion.
Skin irritation, redness, or allergic reactions are possible in susceptible individuals.
Performing a patch test before using products containing this ingredient can help identify any adverse reactions.
PEG 400 Monostearat compounds can sometimes be contaminated with impurities, such as ethylene oxide and 1,4-dioxane, during the manufacturing process.
These contaminants are known to be potential carcinogens.
However, reputable manufacturers take measures to minimize these impurities in their products.
In some cases, PEG 400 Monostearat may contribute to the penetration of other ingredients through the skin, potentially allowing them to be absorbed into the bloodstream.
