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CAS: 25322-68-3
EINECS: 500-038-2
Description
PEG 4000 is a family of linear polymers formed by a base-catalyzed condensation reaction with repeating ethylene oxide units being added to ethylene.
The molecular formula is (C2H4O)multH2O where mult denotes the average number of oxyethylene groups.
The molecular weight can range from 200 to several million corresponding to the number of oxyethylene groups.
The higher-molecular-weight materials (100 000 to 5 000 000) are also referred to as polyethylene oxides.
The average molecular weight of any specific PEG 4000 product falls within quite narrow limits (°5%).
The number of ethylene oxide units or their approximate molecular weight (e.g., PEG-4 or PEG-200) commonly designates the nomenclature of specific PEG 4000.
PEG 4000 with amolecular weight less than 600 are liquid, whereas those of molecular weight 1000 and above are solid.
These materials are nonvolatile, water-soluble, tasteless, and odorless.
They are miscible with water, alcohols, esters, ketones, aromatic solvents, and chlorinated hydrocarbons, but immiscible with alkanes, paraffins, waxes, and ethers.
Any of several condensa-tion polymers of PEG 4000 with thegeneral formula HOCH2(CH2OCH2)nCH2OH orH(OCH2CH2)nOH.
Average molecular weightsrange from 200 to 6000.
Properties vary with molec-ular weight.
PEG 4000 polymers are formed by the reaction of ethylene oxide and water under pressure in the presence of a catalyst.
PEG 4000 is another osmotic laxative that is colorless and tasteless once it is mixed.
PEG 4000 helps in the purification and crystal growth of proteins and nucleic acids.
PEG 4000 also interacts with cell membrane, thereby allowing cell fusion.
PEG 4000 is a polyether compound with many applications from industrial manufacturing to medicine.
The structure of PEG 4000 is (note the repeated element in parentheses):
H-(O-CH2-CH2)n-OH
PEG 4000 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.
PEG 4000 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure :<0.01 mm Hg ( 20 °C)
Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility: H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: PEG 4000 (25322-68-3)
EPA Substance Registry System: PEG 4000 (25322-68-3)
PEG 4000 is a polymer which is hydrolyzed by ethylene oxide.
PEG 4000 has no toxicity and irritation.
PEG 4000 is widely used in various pharmaceutical preparations.
The toxicity of low molecular weight PEG 4000 is relatively large.
In general, the toxicity of diols is very low.
Topical application of PEG 4000, especially mucosal drug, can cause irritant pain.
In topical lotion, PEG 4000 can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin.
PEG 4000 can occur in large doses of oral administration.
In injection, the maximum PEG 4000 300 concentration is about 30% (V/V).
Hemolysis could occur when the concentration is more than 40% (V/V).
The USP32–NF27 describes PEG 4000 as being an addition polymer of ethylene oxide and water.
PEG 4000 grades 200–600 are liquids; grades 1000 and above are solids at ambient temperatures.
Liquid grades (PEG 200–600) occur as clear, colorless or slightly yellow-colored, viscous liquids.
They have a slight but characteristic odor and a bitter, slightly burning taste.
PEG 4000 can occur as a solid at ambient temperatures.
Solid grades (PEG>1000) are white or off-white in color, and range in consistency from pastes to waxy flakes.
They have a faint, sweet odor.
Grades of PEG 4000 and above are available as freeflowing milled powders.
Uses
PEG 4000 is a binder, coating agent, dispersing agent, flavoring adjuvant, and plasticizing agent that is a clear, colorless, viscous, hygroscopic liquid resembling paraffin (white, waxy, or flakes), with a ph of 4.0–7.5 in 1:20 concentration.
PEG 4000 is soluble in water (mw 1,000) and many organic solvents.polyethylene glycol (PEG) is a binder, solvent, plasticizing agent, and softener widely used for cosmetic cream bases and pharmaceutical ointments.
PEG 4000 is quite humectant up to a molecular weight of 500.
Beyond this weight, their water uptake diminishes.
Used in conjunction with carbon black to form a conductive composite.
Polymer nanospheres of PEG 4000 were used for drug delivery.
PEG 4000 molecules of approximately 2000 monomers.
PEG 4000 is used in various applications from industrial chemistry to biological chemistry.
Recent research has shown PEG 4000 maintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals.
In rats, PEG 4000 has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery.
PEG 4000 is industrially produced as a lubricating substance for various surfaces to reduce friction.
PEG 4000 is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.
H2 histamine receptor antagonist, anti-ulcer agent.
A polymer used to precipitate proteins, viruses, DNA and RNA.
PEG 4000 is used to extend the size and durability of very large soap bubbles.
PEG 4000 is the main ingredient in many personal lubricants. (Not to be confused with propylene glycol.)
PEG 4000 is the main ingredient in the paint (known as "fill") in paintballs.
Application in biomedicine
PEG 4000 is also known as polyoxirane (PEO).
PEG 4000 is a linear polyether obtained by ring opening polymerization of ethylene oxide.
The main uses in the field of biomedicine are as follows:
Contact lens liquid.
The viscosity of polyethylene glycol solution is sensitive to the shear rate and PEG 4000 is not easy for bacteria to grow on polyethylene glycol.
Synthetic lubricants.
The condensation polymer of ethylene oxide and water.
PEG 4000 is a cream matrix for preparing water-soluble drugs.
PEG 4000 can also be used as a solvent for acetylsalicylic acid and caffeine, which is difficult to dissolve in water.
Drug sustained-release and immobilized enzyme carrier.
The PEG 4000 solution is applied to the outer layer of the pill to control the diffusion of drugs in the pill so as to improve the efficacy.
Surface modification of medical polymer materials.
The biocompatibility of medical polymer materials in contact with blood can be improved by adsorption, interception and grafting of two amphiphilic copolymers containing polyethylene glycol on the surface of medical polymers.
PEG 4000 can make the membrane of the alkanol contraceptive pill.
PEG 4000 can make hydrophilic anticoagulant polyurethane.
PEG 4000 is an osmotic laxative.
PEG 4000 can increase osmotic pressure and absorb moisture in the intestinal cavity, which makes the stool soften and increase in volume, resulting in bowel movement and defecation.
Denture fixing agent.
Peg nontoxic and gelatinous nature can be used as a component of denture fixer.
PEG 4000 and PEG 6000 are commonly used to promote cell fusion or protoplast fusion and help organisms (such as yeasts) to take DNA in transformation.
PEG 4000 absorbs water from the solution, so it is also used to concentrate the solution.
Pharmaceutical-grade PEG 4000 is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
PEG 4000 is the basis of a number of laxatives (as MiraLax).
Whole bowel irrigation with PEG 4000 and added electrolytes is used for bowel preparation before surgery or colonoscopy.
PEG 4000 is used in medicines for treating disimpaction and maintenance therapy for children with constipation.
When attached to various protein medications or drug carriers, PEG 4000 of suitable length slows down their clearance from the blood.
The possibility that PEG 4000 could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.
An example of PEG 4000 (see Biological uses section) in a therapeutic has been theorized by Ma et al.
They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums.
The gel and encapsulated stem cells was to be injected to the site of disease and crosslinked to create the microenvironment required for the stem cells to function.
PEGylation of adenoviruses for gene therapy can help prevent adverse reactions due to pre-existing adenovirus immunity.
A PEGylated lipid is used as an excipient in both the Moderna and Pfizer–BioNTech vaccines for SARS-CoV-2.
Both RNA vaccines consist of messenger RNA, or mRNA, encased in a bubble of oily molecules called lipids.
Proprietary lipid technology is used for each.
In both vaccines, the bubbles are coated with a stabilizing molecule of polyethylene glycol.
Chemical uses
Because PEG 4000 is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.
PEG 4000 has a low toxicity and is used in a variety of products.
PEG 4000 is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.
Since PEG 4000 is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres).
PEG 4000 also is unlikely to have specific interactions with biological chemicals.
These properties make PEG 4000 one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique.
PEG 4000 is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
PEG 4000 is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases.
PEG 4000 replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, PEG 4000 is used when working with green wood as a stabilizer, and to prevent shrinkage.
PEG 4000 has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.
These painted artifacts were created during the Qin Shi Huang (first emperor of China) era.
Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air.
The paint would subsequently flake off in about four minutes.
The German Bavarian State Conservation Office developed a PEG preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.
PEG 4000 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
PEG 4000 derivatives, such as narrow range ethoxylates, are used as surfactants.
PEG 4000 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
PEG 4000 is a component of the propellent used in UGM-133M Trident II Missiles, in service with the United States Navy.
Preparation
The ring-opening polymerization of ethylene oxide is readily effected by a variety of ionic reagents and several types of polymer have been prepared.
For commercial purposes, poly(ethylene oxide)s of low molecular weight and of very high molecular weight are of interest.
(a) Low molecular weight polymers
Poly(ethylene oxide)s of low molecular weight, i.e. below about 3000, are generally prepared by passing ethylene oxide into ethylene glycol at 120-150°C and about 0.3 MPa (3 atmospheres) pressure, using an alkaline initiator such as sodium hydroxide.
Anionic polymerization proceeds according to the following scheme:
20220127142458
The polymers produced by these methods are thus terminated mainly by hydroxy groups (a few unsaturated end-groups are also formed) and are often referred to as poly(ethylene glycol)s.
Poly(ethylene glycol)s with molecular weights in the range 200-600 are viscous liquids which find use as surfactants in inks and paints and as humectants.
At molecular weights above about 600, poly(ethylene glycol)s are low-melting waxy solids, uses of which include pharmaceutical and cosmetic bases, lubricants and mould release agents.
PEG 4000 may be noted that homogeneous cationic polymerization of ethylene oxide also generally leads to low molecular weight products; typical initiators include aluminium chloride, boron trifluoride and titanium tetrachloride.
Systems of this type are not utilized on a commercial scale.
(b) High molecular weight polymers
Poly(ethylene oxide)s of molecular weight ranging from about 100000 to 5 x 106 and above are available.
Details of the techniques used to manufacture these polymers have not been disclosed, but the essential feature is the use of (generally) heterogeneous initiator systems.
Effective initiators are mainly of two types, namely alkaline earth compounds (e.g. carbonates and oxides of calcium, barium and strontium) and organometallic compounds (e.g. aluminium and zinc alkyls and alkoxides, commonly with added coinitiators).
The precise modes of action of these initiators have not, as yet, been fully resolved.
However, PEG 4000 is now generally thought that polymerization occurs through a co-ordinated anionic mechanism, in which the ethylene oxide is coordinated to the initiator through an unshared electron pair on the oxirane oxygen atom.
Unlike the low molecular weight poly(ethylene oxide)s, the high molecular weight polymers are tough and extensible.
They are highly crystalline, with a melting point of 66°C.
Unlike most water-soluble polymers, the high molecular weight poly(ethylene oxide)s may be melt processed; they may be injection moulded, extruded and calendered without difficulty.
Poly(ethylene oxide)s are soluble in an unusually broad range of solvents, which includes water; chlorinated hydrocarbons such as carbon tetrachloride and methylene dichloride; aromatic hydrocarbons such as benzene and toluene; ketones such as acetone and methyl ethyl ketone; and alcohols such as methanol and isopropanol.
There is an upper temperature limit of solubility in water for the high molecular weight poly(ethylene oxide)s; this varies with concentration and molecular weight but is usually between 90 and 100°C.
Water-solubility is due to the ability of the polyether to form hydrogen bonds with water; these bonds are broken when the temperature is raised, restoring the anhydrous polymer which is precipated from the solution.
High molecular weight poly(ethylene oxide)s find use as water-soluble packaging films and capsules for such products as laundry powders, colour concentrates, tablets and seeds.
In solution, the polymers are used as thickeners in pharmaceutical and cosmetic preparations, textile sizes and latex stabilizers.
Pharmaceutical Applications
PEG 4000 is widely used in a variety of pharmaceutical formulations, including parenteral, topical, ophthalmic, oral, and rectal preparations.
PEG 4000 has been used experimentally in biodegradable polymeric matrices used in controlled-release systems.
PEG 4000 is stable, hydrophilic substances that are essentially nonirritant to the skin; They do not readily penetrate the skin, although the polyethylene glycols are water-soluble and are easily removed from the skin by washing, making them useful as ointment bases.
Solid grades are generally employed in topical ointments, with the consistency of the base being adjusted by the addition of liquid grades of PEG 4000.
Mixtures of PEG 4000 can be used as suppository bases,for which they have many advantages over fats.
For example, the melting point of the suppository can be made higher to withstand exposure to warmer climates; release of the drug is not dependent upon melting point; the physical stability on storage is better; and suppositories are readily miscible with rectal fluids.
PEG 4000 have the following disadvantages: they are chemically more reactive than fats; greater care is needed in processing to avoid inelegant contraction holes in the suppositories; the rate of release of water-soluble medications decreases with the increasing molecular weight of the polyethylene glycol; and PEG 4000 tend to be more irritating to mucous membranes than fats.
Aqueous PEG 4000 solutions can be used either as suspending agents or to adjust the viscosity and consistency of other suspending vehicles.
When used in conjunction with other emulsifiers, PEG 4000 can act as emulsion stabilizers.
Liquid PEG 4000 is used as water-miscible solvents for the contents of soft gelatin capsules.
However, they may cause hardening of the capsule shell by preferential absorption of moisture from gelatin in the shell.
In concentrations up to approximately 30% v/v, PEG 3000 and PEG 4000 have been used as the vehicle for parenteral dosage forms.
In solid-dosage formulations, higher-molecular-weight polyethylene glycols can enhance the effectiveness of tablet binders and impart plasticity to granules.
However, they have only limited binding action when used alone, and can prolong disintegration if present in concentrations greater than 5% w/w.
When used for thermoplastic granulations,a mixture of the powdered constituents with 10–15% w/w PEG 6000 is heated to 70–75°C.
The mass becomes pastelike and forms granules if stirred while cooling.
This technique is useful for the preparation of dosage forms such as lozenges when prolonged disintegration is required.
PEG 4000 can also be used to enhance the aqueous solubility or dissolution characteristics of poorly soluble compounds by making solid dispersions with an appropriate polyethylene glycol.
Animal studies have also been performed using PEG 4000 as solvents for steroids in osmotic pumps.
In film coatings, solid grades of PEG 4000 can be used alone for the film-coating of tablets or can be useful as hydrophilic polishing materials.
Solid grades are also widely used as plasticizers in conjunction with film-forming polymers.
The presence of PEG 4000 in film coats, especially of liquid grades, tends to increase their water permeability and may reduce protection against low pH in enteric-coating films.
PEG 4000 is useful as plasticizers in microencapsulated products to avoid rupture of the coating film when the microcapsules are compressed into tablets.
PEG 4000 grades with molecular weights of 6000 and above can be used as lubricants, particularly for soluble tablets.
The lubricant action is not as good as that of magnesium stearate, and stickiness may develop if the material becomes too warm during compression.
An antiadherent effect is also exerted, again subject to the avoidance of overheating.
PEG 4000 have been used in the preparation of urethane hydrogels, which are used as controlled-release agents.
PEG 4000 has also been used in insulin-loaded microparticles for the oral delivery of insulin;it has been used in inhalation preparations to improve aerosolization;polyethylene glycol nanoparticles have been used to improve the oral bioavailability of cyclosporine;it has been used in self-assembled polymeric nanoparticles as a drug carrier;and copolymer networks of polyethylene glycol grafted with poly(methacrylic acid) have been used as bioadhesive controlled drug delivery formulations.
Synonyms
ETHYLENE GLYCOL
Ethane-1,2-diol
1,2-ethanediol
107-21-1
glycol
monoethylene glycol
1,2-Dihydroxyethane
2-hydroxyethanol
Glycol alcohol
Ethylene alcohol
polyethylene glycol
Macrogol
Fridex
Tescol
Ethylene dihydrate
Norkool
Macrogol 400 BPC
Dowtherm SR 1
ethanediol
Zerex
Poly(ethylene glycol)
Ucar 17
Lutrol-9
Polyethylene glycol 200
ethyleneglycol
Aethylenglykol
Ethylenglycol
1,2-Ethandiol
Polyethylene glycol 1000
1,2-ethylene glycol
1,2-dihydroxy ethane
ethylen glycol
ethylene-glycol
146AR
Polyethylene glycol 3350
Lutrol 9
MFCD00002885
NSC 93876
Carbowax 300
PEG
HOCH2CH2OH
Union Carbide XL 54 Type I De-icing Fluid
PEG 1000
M.e.g.
FC72KVT52F
DTXSID8020597
CHEBI:30742
1, 2-Ethanediol
NSC-93876
DSSTox_CID_597
DSSTox_RID_75680
DSSTox_GSID_20597
Glycol, ethylene-
Glycol, polyethylene
Glycols, polyethylene
Caswell No. 441
Aethylenglykol [German]
Polyethylene oxide
Carbowax 20
CAS-107-21-1
Polyethylene Glycols
Carbowax 400
Carbowax 1000
CCRIS 3744
Dowtherm 4000
HSDB 5012
Ethylene glycol polymer
NCI-C00920
PEG 3350
EINECS 203-473-3
Ethylene glycol homopolymer
Polyethylene Glycol 6000
UNII-FC72KVT52F
EPA Pesticide Chemical Code 042203
1,2-Ethanediol homopolymer
WLN: Q2Q
ethyleneglycole
Athylenglykol
ehtylene glycol
etylene glycol
AI3-03050
2-ethanediol
Polyaethylenglykol
Ilexan E
4-vinyl cathecol
Polyaethylenglykole
MEG 100
Solbanon (TN)
1,2-ethane diol
1,2-ethane-diol
ethane-1.2-diol
GXT
PEG 4000
1,2-ethyleneglycol
ethan-1,2-diol
mono-ethylene glycol
Macrogol 400
Carbowax 1540
1,2-ethylene-glycol
Lutrol E (TN)
NANOSILVER+EG
YLENE GLYCOL
DuPont Zonyl FSO Fluorinated Surfactants
Ethylene glycol-[d6]
alpha-Hydro-omega-hydroxypoly(oxyethylene)
GLYCOL [INCI]
polyethylene glycol-400
Macrogol 400 (TN)
Polyethylene oxide (NF)
Polyethylene glycol (NF)
Sentry polyox WSR (TN)
Ethyleneglycol, ReagentPlus
Macrogol 1500 (TN)
Macrogol 4000 (TN)
Macrogol 6000 (TN)
EC 203-473-3
LOWENOL T-163A
Macrogol ointment (JP17)
Glycol, polyethylene(300)
HO(CH2)2OH
NCIOpen2_001979
NCIOpen2_002019
NCIOpen2_002100
Macrogol 400 (JP17)
ETHYLENE GLYCOL [II]
ETHYLENE GLYCOL [MI]
Polyethylene Glycol 300 NF
alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
Ethylene glycol 5 M solution
MLS002454404
Polyethylene glycol, diglycidyl bisphenol A polymer
BIDD:ER0283
FisherFresh™ Concentrate
Macrogol 1500 (JP17)
Macrogol 4000 (JP17)
Macrogol 6000 (JP17)
ETHYLENE GLYCOL [HSDB]
CHEMBL457299
ETHYLENE GLYCOL [MART.]
Ethylene glycol, AR, >=99%
Ethylene glycol, LR, >=99%
Macrogol 20000 (JP17)
CHEBI:46793
ETHYLENE GLYCOL [USP-RS]
ETHYLENE GLYCOL [WHO-DD]
PEG1000
HMS2267F07
Poly(ethylene glycol) methyl ether
Polyethylene glycol 3350 (USP)
Ethylene glycol, p.a., 99.5%
LOWENOL COPOLYMER 1985-A
LOWENOL COPOLYMER 1985-B
1,2-ETHANEDIOL (GLYCOL)
AMY22336
NSC32853
NSC32854
NSC57859
NSC93876
PEG 3600
PEG-1000
poly (ethylene glycol) methyl ether
STR01171
ZINC5224354
Ethylene glycol, analytical standard
Tox21_202038
Tox21_300637
Ethane-1,2-diol (Ethylene Glycol)
Ethylene glycol, anhydrous, 99.8%
NSC-32853
NSC-32854
NSC-57859
NSC152324
NSC152325
NSC155081
Polyethylene Glycol 8000, NF FCC
STL264188
AKOS000119039
alpha,omega-hydroxypoly(ethylene oxide)
NSC-152324
NSC-152325
NSC-155081
Ethylene glycol, Spectrophotometric grade
NCGC00091510-01
NCGC00091510-02
NCGC00091510-03
NCGC00254292-01
NCGC00259587-01
BP-13454
BP-31056
GLYCEROL IMPURITY B [EP IMPURITY]
Oxirane, 2,2'-((1-methylethylidene)bis(4,1-phenyleneoxymethylene))bis-, polymer with alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
SMR001262244
Dihydrocarveol, (-)-, mixture of isomers
ETHYLENE GLYCOL HIGH PURITY GRD 1L
Ethylene glycol, ReagentPlus(R), >=99%
DuPont Zonyl FSE Fluorinated Surfactants
Residual Solvent Class 2 - Ethylene Glycol
E0105
Ethylene glycol 1000 microg/mL in Methanol
Ethylene glycol, puriss., >=99.5% (GC)
FT-0626292
FT-0692978
1,2-Ethane-1,1,2,2-d4-diol-d2(9ci)
EN300-19312
Ethylene glycol, BioUltra, >=99.5% (GC)
Ethylene glycol, SAJ first grade, >=99.0%
C01380
D03370
D06418
D06419
D06420
D06421
D06422
D06423
Ethylene glycol, JIS special grade, >=99.5%
Ethylene glycol, anhydrous, ZerO2(TM), 99.8%
Ethylene glycol, Vetec(TM) reagent grade, 98%
A851234
Ethylene glycol, spectrophotometric grade, >=99%
Q194207
J-001731
F0001-0142
004143F9-240E-472F-9D5A-B1B13BBA2A18
Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-
Ethylene glycol, United States Pharmacopeia (USP) Reference Standard
PROPYLENE GLYCOL RELATED COMPOUND ETHYLENE GLYCOL [USP IMPURITY]
Ethylene glycol, Pharmaceutical Secondary Standard; Certified Reference Material
Ethylene glycol solution, NMR reference standard, 80% in DMSO-d6 (99.9 atom % D), NMR tube size 3 mm x 8 in.
Ethylene glycol solution, NMR reference standard, 80% in DMSO-d6 (99.9 atom % D), NMR tube size 5 mm x 8 in.
ethylene glycol;1,2-ethanediol;ethane-1,2-diol;glycolethylene glycol;ethanediol;ethylene glycol 1,2-ethanediol ethane-1,2-diol glycolethylene glycol ethanediol
Residual Solvent Class 2 - Ethylene Glycol, United States Pharmacopeia (USP) Reference Standard
