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Pentaethylene Glycol = 3,6,9,12-tetraoxatetradecane-1,14-diol
CAS Number: 4792-15-8
EC Number: 225-341-4
Molecular Formula : C10H22O6
Formula Weight : 238.28
Description of Pentaethylene Glycol
Used as an intermediate in the synthesis of cyclic and noncyclic polyethers, complexing agents and immobilized phase-transfer catalysts.
Pentaethylene Glycol acts as a catalyst for potassium hydroxide induced elimination reactions in benzene.
Further, Pentaethylene Glycol is used in functional fluids and viscosity adjustors.
Pentaethylene glycol is used as an intermediate in the synthesis of cyclic and noncyclic polyethers, complexing agents and immobilized phase-transfer catalysts.
Pentaethylene glycol acts as a catalyst for potassium hydroxide induced elimination reactions in benzene.
Further, Pentaethylene Glycol is used in functional fluids and viscosity adjustors.
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio.
Some documentation and label information may refer to the legacy brand.
The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
Applications of Pentaethylene Glycol
Pentaethylene glycol is used as an intermediate in the synthesis of cyclic and noncyclic polyethers, complexing agents and immobilized phase-transfer catalysts.
It acts as a catalyst for potassium hydroxide induced elimination reactions in benzene.
Further, it is used in functional fluids and viscosity adjustors.
Polymer-supported pentaethylene glycols (PSpentaEG) as promising catalysts for nucleophilic fluorination with alkali metal fluoride (MF) could significantly enhance the nucleophilicity of MF and provide simple purification and recycling in the reaction.
Furthermore, by their synergistic effect, the combination of PSpentaEG and a tert-alcohol media system showed tremendous efficiency in the fluorination of base-sensitive substrates such as sec-alkyl halide.
Use and Manufacturing of Pentaethylene Glycol
Sources/Uses
Used in commercial mixtures (with tri- and tetraethylene glycols) added to brake fluids and in cement grinding; [OECD SIDS - Pentaethylene Glycol] Not manufactured in the pure form in the US; Commercial mixtures with tetraethylene glycol are produced as byproducts following distillation of ethylene, diethylene, and triethylene glycols;
Industrial Processes with risk of exposure
-Cement Producing
Industry Uses
-Functional fluids (closed systems)
-Viscosity adjustors
Household Products
Household & Commercial/Institutional Products
Information on 3 consumer products that contain Pentaethylene glycol in the following categories is provided:
-Auto Products
Specification of Pentaethylene Glycol
Density : 1.126 g/mL
Boiling Point : 338°C to 340°C
Flash Point : >110°C (230°F)
Assay Percent Range : >98%
Beilstein : 1635593
Refractive Index : 1.462
Quantity : 10g
Solubility Information : Miscible with water.
Formula Weight : 238.28
Chemical Name or Material : Pentaethylene glycol
Pentaethylene glycol is a polymer consisting of ethylene glycol monomers and two terminal hydroxyl groups.
The PEG chain increases the water solubility of a compound in aqueous media.
Increasing the number of ethylene glycol units within the entire chain improves the solubility properties of the PEG linker.
Pentaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Pentaethylene glycol is a non-ionic hydrophilic polymer and is available in different molecular weights.
Pentaethylene glycol helps in the purification and crystal growth of proteins and nucleic acids.
Pentaethylene glycol and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials.
Pentaethylene glycol also interacts with cell membrane, thereby allowing cell fusion.
Pentaethylene glycol is a useful research chemical.
Buy high-quality Pentaethylene glycol from Biosynth-Carbosynth for a variety of research applications.
We also offer Pentaethylene glycol in bulk quantities in addition to our standard pack sizes.
Orion Chem is manufacturer of Pentaethylene glycol in india, with state of art manufacturing facilites in MIDC Tarapur, Maharashtra, India , our utmost attention is given to generate quality products meeting stringent and demanding specifications of user industries.
Pentaethylene glycol is used an intermediate in the synthesis of cyclic and noncyclic polyethers, complexing agents and immobilized phase-transfer catalysts.
Pentaethylene glycol is applicated in medical research, drug-release, nanotechnology and new materials research, cell culture.
In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
Pentaethylene glycol is part of a group of compounds called polyethylene glycols (PEGs), which are major byproducts of non-ionic surfactants biodegradation. Pentaethylene glycol is a useful synthetic intermediate, and is used as a reagent to synthesize macrocyclic oligoesters through lipase-catalysis.
Pentaethylene glycol is a class of PEG linker with one side of PEG containing a carboxylic acid (CO2H) group.
Pentaethylene glycol will react with an amine-containing moiety in the presence of coupling reagents such as EDC, HATU.
Pentaethylene glycol can also be converted to a N-hydroxysuccinimide active ester which is widely used in bioconjugation.
First-aid measures of Pentaethylene Glycol
Eye Contact
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Get medical attention.
Skin Contact
Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.
Get medical attention.
Inhalation
Remove from exposure, lie down.
Remove to fresh air.
If breathing is difficult, give oxygen.
If not breathing, give artificial respiration.
Get medical attention.
Ingestion
Clean mouth with water.
Get medical attention.
Handling and storage of Pentaethylene Glycol
Handling
Avoid contact with skin and eyes.
Do not breathe mist/vapors/spray.
Storage
Keep in a dry, cool and well-ventilated place.
Keep container tightly closed.
Incompatible Materials.
Strong oxidizing agents.
Acid anhydrides.
Acid chlorides.
Stability and reactivity of Pentaethylene Glycol
Reactive Hazard :None known, based on information available
Stability : Stable under normal conditions. Conditions to Avoid Incompatible products.
Incompatible Materials : Strong oxidizing agents, Acid anhydrides, Acid chlorides
Hazardous Decomposition Products : Carbon monoxide (CO), Carbon dioxide (CO2)
Hazardous Polymerization : No information available.
Hazardous Reactions : None under normal processing.
Pentaethylene glycol is a colorless, odorless, and slightly viscous liquid and miscible with water in all proportions.
This grade is used where high purity is required.
Ethylene glycol is produced from ethylene, via the internediate ethylene oxide.
Ethylene oxide reacts with water to produce ethylene glycol according to the chemical equation.
Pentaethylene glycol can be used for applications that require chemical intermediates for resins, solvent couplers, freezing point depression, solvents, humectants and chemical intermediates.
These applications are vital to the manufacture of a wide range of products, including resins; deicing
fluids; heat transfer fluids; automotive antifreeze and coolants; water-based adhesives, latex paints and
asphalt emulsions; electrolytic capacitors; textile fibers; paper and leather.
- Polyester resins ( fibers, containers and films )
- Resin esters as plasticizers ( adhesives, lacquers and enamels )
- Alkyd-type resins ( synthetic rubbers, adhesives, surface coatings )
- Stabilizer against gel formation
- Freezing point depression
- Deicing fluids ( aircraft, runway )
- Heat transfer fluids ( gas compressors, heating, ventilating, air conditioning, process chillers )
- All-weather automotive antifreeze and coolants
- Water-based formulations ( adhesives, latex paints, asphalt emulsions )
- Medium for suspending conductive salt in electrolytic capacitors
- Textile fibers
- Paper
- Leather
- Adhesives
- Glue
Substance identity
EC / List no.: 225-341-4
CAS no.: 4792-15-8
Mol. formula: C10H22O6
Hazard classification & labelling of Pentaethylene Glycol
Warning! According to the classification provided by companies to ECHA in CLP notifications this substance causes serious eye irritation, causes skin irritation and may cause respiratory irritation.
Synonyms:
3,6,9,12-tetraoxatetradecane-1,14-diol
3,6,9,12-Tetraoxatetradecane-1,14-diol
3,6,9,12-tetraoxatetradecane-1,14-diol
3,6,9,12-Tetraoxatetradocane-1,14-diol
Pentaethylene glycol
3,6,9,12-Tetraoxatetradecane-1,14-diol
3,6,9,12-tetraoxatetradecane-1,14-diol
PENTAETHYLENE GLYCOL
Pentaethylene Glycol
Pentaethylene glycol
1186024-62-3
4792-15-8
942939-01-7
Pentaethylene glycol
4792-15-8
3,6,9,12-Tetraoxatetradecane-1,14-diol
HO-PEG5-OH
PENTAETHYLENEGLYCOL
2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethanol
Pentaglycol
PEG400
HO[CH2CH2O]5H
Hydroxypropyl starch phosphate
MFCD00002878
113894-92-1
CHEBI:39631
DSSTox_CID_7579
DSSTox_RID_78510
DSSTox_GSID_27579
CAS-4792-15-8
EINECS 225-341-4
BRN 1635593
2-(2-{2-[2-(2-Hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethanol
2-[2-[2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy]-ethoxy]-ethanol
3,6,9,12-Tetraoxatetradocane-1,14-diol
C10H22O6
Pentaethylene glycol, 98%
SCHEMBL45272
4-01-00-02405 (Beilstein Handbook Reference)
CHEMBL1229766
DTXSID4027579
AMY4487
ZINC4283769
Tox21_201721
Tox21_303127
AKOS015839786
CS-W007341
DS-4289
HY-W007341
MCULE-3214557644
NCGC00164364-01
NCGC00164364-02
NCGC00257199-01
NCGC00259270-01
BP-21065
SY010536
DB-070885
FT-0701756
P1154
Y4952
Amylopectin, phosphate, 2-hydroxypropyl ether
S10674
A872019
W-106062
Q15656852
