PERMETHRIN

Permethrin is a synthetic pyrethroid insecticide widely used for control of a broad range of insects through contact and stomach action, with rapid knockdown and residual activity on treated surfaces.
Permethrin is commonly used in public health, veterinary, household, textile, and agricultural applications where effective control of crawling and flying insects is needed at low use levels.
Permethrin is valued for strong efficacy, broad-spectrum performance, and formulation flexibility, but Permethrin requires careful handling due to aquatic toxicity and potential sensitivity in certain animals.

CAS Number: 52645-53-1
EC Number: 258-067-9
Molecular Formula: C21H20Cl2O3
Molecular Weight: 391.29 g/mol

Synonyms: Permethrin, 3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate, Permethrin Insecticide, Pyrethroid Permethrin, cis/trans Permethrin (mixture), Permethrin Technical, Permethrin Concentrate, Permethrin EC, Permethrin WP, Permethrin Textile Treatment, Permethrin Residual Insecticide, Synthetic Pyrethroid Insecticide, Permethrin, C21H20Cl2O3, Permethrin Insecticide, Permethrin Pesticide, Permethrin Pyrethroid, Synthetic Pyrethroid Permethrin, 3-Phenoxybenzyl (±)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylate, (±)-cis,trans-Permethrin, cis,trans-Permethrin, trans-Permethrin, cis-Permethrin, Permethrin Mixture of Isomers, Permethrin Technical, Permethrin Technical Grade, Permethrin Active Ingredient, Permethrin Concentrate, Permethrin Emulsifiable Concentrate, Permethrin EC, Permethrin WP, Permethrin Wettable Powder, Permethrin SC, Permethrin Suspension Concentrate, Permethrin ULV, Permethrin Aerosol, Permethrin Dust, Permethrin Lotion, Permethrin Cream, Permethrin 1% Cream, Permethrin 5% Cream, Permethrin Shampoo, Permethrin Solution, Permethrin Spray, Permethrin Impregnation Grade, Permethrin Textile Treatment, Permethrin Fabric Protector, Permethrin Mosquito Repellent Treatment, Permethrin Tick Repellent Treatment, Permethrin Insect Repellent Treatment, Permethrin Termiticide, Permethrin Household Insecticide, Permethrin Veterinary Insecticide, Permethrin Ectoparasiticide, Permethrin Pediculicide, Permethrin Scabicide, Permethrin Lice Treatment, Permethrin Scabies Treatment, Permethrin Reagent, Permethrin Analytical Standard, Permethrin Reference Standard, Permethrin (CAS 52645-53-1), Permethrin (ISO), Permethrin (INN), NRDC 143, Ambush, Pounce, Permethrin S, Permethrin S-(-), Permethrin R-(+), (1R,3R)-Permethrin, (1S,3S)-Permethrin, (1R,3S)-Permethrin, (1S,3R)-Permethrin, 3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

APPLICATIONS

Permethrin is used in residual surface treatments to control crawling insects such as ants, cockroaches, and spiders in suitable environments.
Permethrin is used in perimeter treatments around buildings to reduce insect entry and nesting activity.
Permethrin is incorporated into household insecticide products where long-lasting control on treated surfaces is desired.

Permethrin is used in aerosol and spray formulations for flying insects such as mosquitoes and flies in compatible application designs.
Permethrin is used in space spraying concepts where rapid knockdown is required under controlled conditions.
Permethrin is used in outdoor pest control programs to reduce mosquito populations in targeted areas.

Permethrin is used in public health vector control programs to reduce mosquito and tick exposure where regulations allow use.
Permethrin is applied in tick control strategies in outdoor settings to reduce tick presence on vegetation and treated zones.
Permethrin is used in integrated pest management programs as a residual option when paired with monitoring and sanitation measures.

Permethrin is used in veterinary ectoparasite control products to help manage fleas, ticks, and lice in approved animal uses.
Permethrin is incorporated into topical veterinary formulations where controlled dosing supports effective parasite control.
Permethrin is used in livestock environments to reduce biting flies and other pests in compatible husbandry programs.

Permethrin is used in textile and fabric treatments to provide insect-repellent and insecticidal performance against mosquitoes and ticks.
Permethrin is incorporated into treated clothing concepts for outdoor and occupational protection in approved markets.
Permethrin is used in treated bed nets and netting systems in some programs where long-lasting insecticidal performance is required.

Permethrin is used in agricultural insect control to manage pests on crops where permitted and according to label directions.
Permethrin is used in greenhouse and field applications to control chewing and sucking insects in integrated crop programs.
Permethrin is incorporated into pest rotation strategies to manage insect pressure while supporting resistance management plans.

Permethrin is used in stored-product and facility pest control to reduce infestation of insects in controlled areas where approved.
Permethrin is applied in warehouse and processing facility treatments to reduce insect activity in cracks, crevices, and structural zones.
Permethrin is used in pest control service applications as a residual insecticide in accordance with local regulations.

Permethrin is used in wood and building material protection systems in some applications to deter insect damage in approved uses.
Permethrin is incorporated into protective coatings where insect control on treated surfaces is part of the performance target.
Permethrin is used in outdoor equipment and gear treatments where insect exposure reduction is desired.

Permethrin is used in household garden insect control products for ornamental plants where label directions allow application.
Permethrin is incorporated into ready-to-use sprays to control common garden insects with residual effect.
Permethrin is used in lawn and landscape pest control to reduce insect pests in targeted treatment zones.

Permethrin is used in product development to create emulsifiable concentrates, wettable powders, suspension concentrates, and microencapsulated systems.
Permethrin is incorporated into microencapsulated formulations to improve residual performance and reduce odor and staining potential.
Permethrin is valued in many markets because Permethrin provides effective insect control at low dosage with flexible formulation options.

Permethrin is used as a synthetic pyrethroid insecticide for controlling a wide range of insects.
Permethrin is applied in public health programs to reduce populations of disease-vector mosquitoes.
Permethrin supports integrated vector management strategies when used according to approved labels.

Permethrin is used in agriculture to protect crops from chewing and sucking insect pests.
Permethrin is applied to field crops to reduce yield loss caused by insect feeding.
Permethrin supports pest control programs in rotations to help manage resistance pressure.

Permethrin is used in horticulture for pest control on fruits, vegetables, and ornamentals.
Permethrin helps control caterpillars, beetles, and other damaging pests on plants.
Permethrin supports improved plant quality and marketability in managed cultivation.

Permethrin is used in greenhouse operations as part of insect management.
Permethrin helps reduce infestations of pests that damage leaves, stems, and flowers.
Permethrin supports cleaner production environments when incorporated into an overall IPM plan.

Permethrin is used in forestry and landscape management for insect control in certain contexts.
Permethrin helps reduce defoliating insects that stress trees and shrubs.
Permethrin supports protection of ornamental and recreational green areas under regulated use.

Permethrin is used in structural pest control to manage crawling insects around buildings.
Permethrin is applied in professional pest management programs for perimeter and crack-and-crevice control.
Permethrin supports long-lasting residual control on suitable treated surfaces.

Permethrin is used in household insect control products in approved consumer formats.
Permethrin helps control insects such as ants, cockroaches, and other nuisance pests.
Permethrin supports improved indoor comfort by reducing insect presence when used as directed.

Permethrin is used in termite control programs in certain formulations and treatment approaches.
Permethrin helps create protective zones against termite intrusion in construction settings.
Permethrin supports building protection programs where permitted by local regulations.

Permethrin is used in livestock protection to reduce biting flies and external parasites.
Permethrin is applied in veterinary-approved products for animals to help manage ectoparasites.
Permethrin supports animal comfort and productivity by reducing pest stress.

Permethrin is used in animal housing and barn environments to control insects.
Permethrin helps reduce fly pressure in facilities with livestock or poultry operations.
Permethrin supports sanitation programs by reducing insect vectors associated with waste.

Permethrin is used in aquaculture facility perimeter control in certain regulated situations.
Permethrin supports insect management around water-adjacent infrastructure where allowed.
Permethrin helps reduce pest burdens that affect workers and nearby operations.

Permethrin is used in public health mosquito control operations for barrier treatments in some programs.
Permethrin supports reduction of mosquito resting populations on treated vegetation or surfaces.
Permethrin helps lower human–mosquito contact rates in targeted areas.

Permethrin is used in insecticide-treated textiles for vector bite prevention.
Permethrin is incorporated into fabrics to provide long-lasting insect-repellent and insecticidal activity.
Permethrin supports protective clothing concepts for outdoor work and travel.

Permethrin is used in military and occupational safety garments to reduce insect bites.
Permethrin supports protection for personnel working in tick- and mosquito-prone environments.
Permethrin helps reduce the likelihood of insect vector contact during field operations.

Permethrin is used in outdoor recreation clothing and gear treatments in approved products.
Permethrin supports treated socks, pants, and outdoor equipment aimed at reducing tick contact.
Permethrin helps improve comfort during hiking, camping, and hunting activities when used appropriately.

Permethrin is used in medical settings as a topical scabicide and pediculicide in certain approved formulations.
Permethrin is applied in treatment regimens for scabies under healthcare guidance.
Permethrin supports management of head lice in pediatric and adult care when used as directed.

Permethrin is used in community health programs to manage outbreaks of lice or scabies.
Permethrin supports coordinated treatment strategies that reduce reinfestation risk.
Permethrin helps improve patient outcomes when combined with hygiene and environmental measures.

Permethrin is used in veterinary medicine to control fleas and ticks in certain animal products.
Permethrin supports external parasite control programs to reduce discomfort and disease transmission.
Permethrin helps protect animals in environments with high tick and flea pressure.

Permethrin is used in kennel and shelter pest management to reduce parasite loads.
Permethrin supports facility-wide control of fleas and other pests when paired with cleaning protocols.
Permethrin helps reduce reinfestation cycles in high-density animal environments.

Permethrin is used in stored-product protection to reduce insect damage in certain storage contexts.
Permethrin supports pest management in storage facilities by controlling insects that infest goods.
Permethrin helps maintain product quality and reduce economic losses when used legally.

Permethrin is used in grain handling and storage protection in specific regulated applications.
Permethrin helps control beetles and moths that can infest stored commodities.
Permethrin supports post-harvest protection strategies under compliance requirements.

Permethrin is used in turf and lawn care to control insects that damage grass and ornamental landscapes.
Permethrin helps manage pests such as grubs and surface-feeding insects in treated areas.
Permethrin supports improved lawn appearance and resilience in managed properties.

Permethrin is used in public space pest management, including parks and recreational areas, where permitted.
Permethrin helps reduce nuisance insects that affect visitor comfort.
Permethrin supports seasonal insect management programs under professional supervision.

Permethrin is used in pest control around food-handling areas in restricted, compliant manners.
Permethrin supports insect control in non-food-contact zones following strict regulations.
Permethrin helps reduce pest entry and harborage near facilities.

Permethrin is used as part of resistance management plans by alternating insecticides with different modes of action.
Permethrin supports reduced selection pressure when used responsibly and not overapplied.
Permethrin helps maintain longer-term effectiveness in coordinated pest management programs.

Permethrin is used in research studies evaluating insecticide efficacy and residual performance.
Permethrin supports standardized bioassays against mosquitoes, flies, and other insects.
Permethrin helps generate comparative data for product development and regulatory testing.

Permethrin is used in toxicology and environmental fate studies as a reference pyrethroid compound.
Permethrin supports assessment of degradation pathways and exposure modeling.
Permethrin helps evaluate risk management measures in controlled research settings.

Permethrin is used in formulation development to optimize stability, adhesion, and residual activity.
Permethrin supports development of emulsifiable concentrates, wettable powders, and microencapsulated formats.
Permethrin helps tailor performance for different application environments and target pests.

Permethrin is used in household and institutional pest control programs as a residual insecticide option.
Permethrin supports coordinated treatments that include sanitation, exclusion, and monitoring.
Permethrin helps achieve longer intervals between treatments when conditions are suitable.

Permethrin is used in humanitarian and disaster response settings to support vector bite prevention measures.
Permethrin supports treated materials used in temporary shelters and field operations.
Permethrin helps reduce nuisance bites and vector exposure under approved deployment practices.

Permethrin is used in traveler health preparations through treated clothing strategies in approved products.
Permethrin supports bite reduction in areas with high tick or mosquito activity.
Permethrin helps complement physical barriers and other personal protection measures.

Permethrin is used in compliance-driven pest management for certain industrial sites with insect issues.
Permethrin supports insect control around warehouses, loading docks, and utility spaces.
Permethrin helps reduce pest-related contamination risks when used appropriately.

Permethrin is used in educational and training programs for pest management professionals.
Permethrin supports instruction on pyrethroid properties, safety practices, and resistance concepts.
Permethrin helps demonstrate best practices for responsible insecticide stewardship.

Permethrin is used in product quality control to verify active content and performance consistency.
Permethrin supports batch testing and stability monitoring across storage conditions.
Permethrin helps ensure labeled strength and predictable efficacy in finished products.

Permethrin is used in integrated tick management programs in certain environments.
Permethrin supports reduction of tick activity through targeted treatments and habitat measures.
Permethrin helps lower tick-human contact risk as part of broader prevention efforts.

Permethrin is used in community mosquito control planning alongside source reduction and surveillance.
Permethrin supports targeted intervention when mosquito populations exceed thresholds.
Permethrin helps reduce biting pressure and potential disease transmission when deployed responsibly.

Permethrin is used in laboratory development of insect-repellent and insecticidal textile technologies.
Permethrin supports testing of wash durability and long-term efficacy on fabrics.
Permethrin helps optimize binding methods to improve retention through laundering.

Permethrin is used in manufacturing of insect-control products requiring a fast-acting pyrethroid active.
Permethrin supports formulation of sprays, concentrates, and treated materials in approved categories.
Permethrin helps provide quick knockdown and residual activity in many use cases.

Permethrin is used in nuisance insect control where rapid knockdown is needed.
Permethrin helps reduce visible insect activity shortly after application in suitable settings.
Permethrin supports improved comfort in residential and commercial environments when used correctly.

Permethrin is used in pest control programs targeting flies in waste and sanitation-adjacent environments.
Permethrin supports reduction of fly populations near dumpsters and service areas where permitted.
Permethrin helps improve hygiene conditions when combined with proper waste management.

Permethrin is used in insect control for certain public transportation and facility maintenance contexts.
Permethrin supports treatment programs that reduce crawling insects in non-sensitive areas.
Permethrin helps maintain user comfort and cleanliness under regulated procedures.

Permethrin is used as a pyrethroid standard in analytical chemistry for method calibration.
Permethrin supports chromatographic method development for pesticide residue analysis.
Permethrin helps validate detection and quantification in environmental and food testing labs.

Permethrin is used in monitoring programs for pesticide residues in agriculture and water systems.
Permethrin supports reference standards used to verify lab accuracy.
Permethrin helps enable compliance testing for regulatory limits.

Permethrin is used in routine pest control decision-making as one option among multiple control tools.
Permethrin supports targeted application strategies based on monitoring results.
Permethrin helps minimize unnecessary treatments when integrated with prevention measures.

Permethrin is used in controlled research to understand insect behavior changes after pyrethroid exposure.
Permethrin supports studies of knockdown, repellency, and sublethal effects.
Permethrin helps improve design of more effective and sustainable insect control programs.

Permethrin is used in specialty insect control products designed for long-lasting residual action.
Permethrin supports microencapsulation technologies that extend performance on surfaces.
Permethrin helps maintain efficacy under environmental exposure in certain formulations.

Permethrin is used in pest management programs for schools, hospitals, and public facilities under strict policies.
Permethrin supports targeted use when non-chemical measures are insufficient.
Permethrin helps control pests while maintaining compliance with safety requirements.

DESCRIPTION

Permethrin is typically a colorless to pale yellow liquid or low-melting solid depending on grade and isomer ratio, and Permethrin is often supplied as a technical material or formulated concentrate.
Permethrin is a synthetic pyrethroid that acts primarily on insect nervous systems by disrupting sodium channel function, leading to paralysis and death.
Permethrin is commonly supplied as a mixture of cis and trans isomers, and the cis/trans ratio can affect efficacy, persistence, and formulation behavior.

Permethrin is poorly soluble in water and is typically formulated using solvents, emulsifiers, or encapsulation systems to enable practical application.
Permethrin binds to surfaces and can provide residual activity, but sunlight, heat, and surface type can influence how long Permethrin remains effective.
Permethrin can cause skin tingling or irritation in some individuals, and exposure control and hygiene are important during handling and application.

Permethrin is highly toxic to aquatic organisms and can be hazardous to cats, so environmental protection and correct use restrictions are essential.
Permethrin should be used only according to applicable regulations and product label instructions, especially regarding dose, re-entry, and treated-area ventilation.
Permethrin should be stored securely and handled with care to prevent accidental exposure, spills, and environmental release.

Permethrin is a synthetic pyrethroid insecticide derived from pyrethrin-inspired chemistry.
Permethrin is typically supplied as a technical-grade liquid or as formulated concentrates and treated products.
Permethrin is lipophilic and has low solubility in water compared with many polar chemicals.

Permethrin acts on insect nervous systems by affecting voltage-gated sodium channels.
Permethrin can produce rapid knockdown in many susceptible insects.
Permethrin residual activity depends on formulation, surface type, and environmental exposure.

Permethrin is often used because it combines strong efficacy with practical formulation flexibility.
Permethrin is commonly formulated as emulsifiable concentrates, suspension concentrates, or microencapsulated products.
Permethrin can be incorporated into textiles to provide durable insect control effects.

Permethrin can degrade under sunlight and environmental conditions, with stability depending on exposure and formulation.
Permethrin persistence varies in soil and on surfaces based on temperature, UV light, and moisture.
Permethrin tends to bind to organic matter due to its hydrophobic nature.

Permethrin should be handled with care because it can be harmful if misused or overexposed.
Permethrin may cause skin or eye irritation depending on concentration and contact duration.
Permethrin inhalation exposure should be minimized through appropriate handling and ventilation.

Permethrin is highly toxic to many aquatic organisms, so environmental precautions are important.
Permethrin use typically includes restrictions to prevent contamination of water bodies.
Permethrin risk management relies on label compliance and appropriate disposal practices.

Permethrin is used in human medicine in specific topical products at controlled concentrations.
Permethrin medical use typically follows guidance to minimize irritation and maximize effectiveness.
Permethrin is generally not intended for internal use and must be used only in approved formats.

Permethrin can contribute to resistance development in insect populations if overused.
Permethrin stewardship commonly involves rotation with different insecticide classes and non-chemical measures.
Permethrin effectiveness is best maintained through integrated pest management approaches.

Permethrin should be stored in tightly closed containers away from heat, ignition sources, and strong oxidizers.
Permethrin product safety and handling requirements depend on the specific formulated product and concentration.

PROPERTIES

Chemical Formula: C21H20Cl2O3
Molecular Weight: 391.29 g/mol
Common Name: Permethrin
Chemical Type: Synthetic pyrethroid insecticide
Appearance: Colorless to pale yellow liquid or low-melting solid (grade and isomer dependent)
Odor: Mild characteristic odor (formulation dependent)
Solubility: Practically insoluble in water; soluble in many organic solvents (grade dependent)
Melting Point: Isomer/grade dependent (often near room temperature for some grades)
Vapor Pressure: Low (typical for pyrethroids; temperature dependent)
LogP: High lipophilicity (typical; supports surface binding and residual effect)
Stability: Stable under normal storage; degraded by strong oxidizers and can degrade with prolonged UV exposure
Flash Point: Formulation dependent; technical material and solvent systems vary widely
Storage Temperature: 15–25°C, tightly closed, protected from light and heat
Shelf Life: Typically 24 months in original sealed packaging (supplier dependent)

FIRST AID

Inhalation:
Move to fresh air immediately if vapors or aerosols are inhaled.
Seek medical attention if coughing, dizziness, headache, or breathing difficulty occurs.
Keep the person at rest and monitor breathing.

Skin Contact:
Remove contaminated clothing and wash skin with soap and plenty of water.
Seek medical advice if irritation, tingling sensation, or redness persists.
Wash contaminated clothing before reuse and clean contaminated footwear.

Eye Contact:
Rinse cautiously with water for several minutes and continue rinsing.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if pain, redness, or visual disturbance persists.

Ingestion:
Rinse mouth with water and do not induce vomiting unless directed by medical personnel.
Seek immediate medical attention, especially if a significant amount is swallowed.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically and supportively.
Consider potential neurotoxic symptoms and manage as clinically indicated.
If aspiration risk exists due to solvent-based formulations, manage airway protection accordingly.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including chemical-resistant gloves, safety goggles, and protective clothing.
Avoid inhalation of spray mist and avoid skin contact during mixing, loading, and application.
Do not eat, drink, or smoke during handling, and wash thoroughly after use.

Ventilation:
Use in well-ventilated areas and avoid application in confined spaces without adequate ventilation.
Use local exhaust where aerosols or vapors may be generated during mixing and filling.
Follow site procedures for respiratory protection when handling concentrates or spraying.

Storage:
Store in tightly closed, properly labeled containers in a cool, dry, secure area.
Keep away from heat, sparks, open flames, and strong oxidizers.
Keep away from food, feed, and water sources, and prevent access by children and unauthorized persons.

Spill and Leak Procedures:
Contain spills and prevent entry into drains, soil, and waterways.
Absorb with inert material and collect into suitable containers for disposal.
Clean the area with detergent and water and dispose according to local regulations and site procedures.

Handling Precautions:
Protect aquatic environments and do not discharge Permethrin-containing waste to waterways.
Avoid use around cats and ensure animal safety by following product-specific restrictions and approved use directions.
Rotate stock using FIFO practices and follow all label requirements, including application rates, re-entry intervals, and disposal instructions.