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PERMETHRIN


Permethrin is a synthetic pyrethroid insecticide modeled after natural pyrethrins.
Permethrin acts on insect nervous systems by affecting voltage-gated sodium channels.
Permethrin produces knockdown and residual insecticidal activity on treated surfaces.

CAS Number: 52645-53-1
EC Number: 258-067-9
Molecular Formula: C21H20Cl2O3
Molecular Weight: 391.29 g/mol

Synonyms: Permethrin, Permetrin (variant spelling), Permethrin Insecticide, Synthetic Pyrethroid Permethrin, 3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate, Permethrin Technical, Permethrin 25:75 cis/trans (common grade), Permethrin 40:60 cis/trans (common grade), Permethrin Concentrate, Permethrin Ectoparasiticide, Permethrin Tick Repellent, Permethrin Mosquito Control Agent, Permethrin, C21H20Cl2O3, Permethrin Insecticide, Permethrin Pesticide, Permethrin Pyrethroid, Synthetic Pyrethroid Permethrin, 3-Phenoxybenzyl (±)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylate, (±)-cis,trans-Permethrin, cis,trans-Permethrin, trans-Permethrin, cis-Permethrin, Permethrin Mixture of Isomers, Permethrin Technical, Permethrin Technical Grade, Permethrin Active Ingredient, Permethrin Concentrate, Permethrin Emulsifiable Concentrate, Permethrin EC, Permethrin WP, Permethrin Wettable Powder, Permethrin SC, Permethrin Suspension Concentrate, Permethrin ULV, Permethrin Aerosol, Permethrin Dust, Permethrin Lotion, Permethrin Cream, Permethrin 1% Cream, Permethrin 5% Cream, Permethrin Shampoo, Permethrin Solution, Permethrin Spray, Permethrin Impregnation Grade, Permethrin Textile Treatment, Permethrin Fabric Protector, Permethrin Mosquito Repellent Treatment, Permethrin Tick Repellent Treatment, Permethrin Insect Repellent Treatment, Permethrin Termiticide, Permethrin Household Insecticide, Permethrin Veterinary Insecticide, Permethrin Ectoparasiticide, Permethrin Pediculicide, Permethrin Scabicide, Permethrin Lice Treatment, Permethrin Scabies Treatment, Permethrin Reagent, Permethrin Analytical Standard, Permethrin Reference Standard, Permethrin (CAS 52645-53-1), Permethrin (ISO), Permethrin (INN), NRDC 143, Ambush, Pounce, Permethrin S, Permethrin S-(-), Permethrin R-(+), (1R,3R)-Permethrin, (1S,3S)-Permethrin, (1R,3S)-Permethrin, (1S,3R)-Permethrin, 3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate, 3-Phenoxybenzyl DVP Cyclopropanecarboxylate, Permethrin (cis/trans 25:75), Permethrin (cis/trans 40:60)

APPLICATIONS


Permethrin is used as a broad-spectrum insecticide in public health vector control programs.
Permethrin is used to reduce mosquito populations in targeted outdoor treatments under professional protocols.
Permethrin is used in integrated pest management strategies as a residual insecticidal component.

Permethrin is used in household insect control products designed to manage crawling insects.
Permethrin is used to control ants, cockroaches, and other nuisance insects in approved formulations.
Permethrin is used in perimeter treatments around buildings when applied by trained personnel.

Permethrin is used in agricultural pest control to protect crops from insect damage.
Permethrin is used on field crops to control chewing and sucking insects where registered.
Permethrin is used in orchard and vegetable programs to reduce yield losses from insect pests.

Permethrin is used in greenhouse pest management as part of rotation programs.
Permethrin is used to suppress insect outbreaks in protected cultivation when permitted.
Permethrin is used to support resistance management by alternating modes of action.

Permethrin is used in livestock protection to help control flies and ectoparasites on animals.
Permethrin is used in veterinary-approved products for tick and lice control on livestock.
Permethrin is used to reduce biting insect pressure in animal housing environments where permitted.

Permethrin is used in companion animal parasite control products in regions where approved.
Permethrin is used in certain tick and flea control systems for dogs under labeled products.
Permethrin is used to reduce reinfestation pressure in pet environments when used responsibly.

Permethrin is used in human health care as a topical pediculicide for head lice treatment in approved medicines.
Permethrin is used as a topical scabicide for scabies management in approved medical products.
Permethrin is used in clinical protocols under label directions and medical guidance.

Permethrin is used in institutional pest control for facilities that require residual insect management.
Permethrin is used in food-handling area pest programs only when regulations and professional practices allow.
Permethrin is used in warehouse and storage pest control plans to protect stored goods.

Permethrin is used in stored-product pest control to manage insects affecting grains and packaged commodities.
Permethrin is used to protect storage structures from insect infestations where registered.
Permethrin is used as part of sanitation-plus-treatment strategies to reduce pest recurrence.

Permethrin is used in textile and material treatments to provide insect-repellent performance in finished goods.
Permethrin is used in treated clothing and uniforms to reduce tick and mosquito bites in outdoor settings.
Permethrin is used in military and occupational garments where certified treatment is available.

Permethrin is used in outdoor gear treatments such as nets and covers to reduce insect contact.
Permethrin is used in mosquito net impregnation programs in some regions to support malaria prevention strategies.
Permethrin is used in camping and field equipment treatments when supplied as regulated products.

Permethrin is used in structural pest control for termites and wood-destroying insects in registered systems.
Permethrin is used in barrier and soil treatments around foundations when performed by licensed operators.
Permethrin is used to support long-lasting protection in construction-related pest control applications.

Permethrin is used in landscape and ornamental plant protection to manage insect pests.
Permethrin is used on turf and ornamentals to reduce damage from beetles and caterpillars where permitted.
Permethrin is used in municipal grounds maintenance programs under pesticide regulations.

Permethrin is used in mosquito control operations as a component of adulticide products in some jurisdictions.
Permethrin is used in ultra-low-volume applications only by authorized professionals following local rules.
Permethrin is used to complement larval source management in community vector control.

Permethrin is used in research laboratories to study insect neurophysiology and knockdown mechanisms.
Permethrin is used in efficacy testing to compare insecticide susceptibility across insect populations.
Permethrin is used in resistance monitoring programs to guide pest management decisions.

Permethrin is used in quality control testing to verify active content in pesticide formulations.
Permethrin is used in stability studies to evaluate shelf life under heat and light stress.
Permethrin is used in formulation development to optimize residual performance on different surfaces.

Permethrin is used in industrial hygiene programs to reduce insect presence in waste handling areas.
Permethrin is used in sanitation-adjacent pest programs for facilities managing organic residues.
Permethrin is used to reduce fly pressure around collection and transfer points where permitted.

Permethrin is used in emergency response stockpiles for vector control during outbreaks in some regions.
Permethrin is used to support rapid deployment pest control strategies under public health oversight.

Permethrin is used in public health mosquito control programs to reduce adult mosquito populations in approved application formats.
Permethrin is incorporated into residual sprays for indoor and outdoor insect control when permitted and properly applied.
Permethrin is used in barrier treatments around buildings to control crawling and flying insects.

Permethrin is used in household insect sprays to control ants, cockroaches, mosquitoes, and other common pests in approved products.
Permethrin is incorporated into aerosol and pump-spray formulations designed for domestic pest management.
Permethrin is used in crack-and-crevice treatments for targeted control of insects in structural pest control.

Permethrin is used in vector-control textiles where fabric is treated to repel or kill mosquitoes and ticks.
Permethrin is incorporated into insect-repellent clothing systems used for outdoor work and recreation.
Permethrin is used in military and occupational clothing programs to reduce insect bites and vector-borne disease risk.

Permethrin is used in veterinary ectoparasite control products for dogs and livestock to manage ticks, fleas, and mites in approved formulations.
Permethrin is incorporated into livestock premises sprays to reduce fly and insect pressure in animal housing.
Permethrin is used in agricultural and farm settings for pest management where permitted by local regulations.

Permethrin is used in lice-treatment pharmaceuticals and medical products in regulated preparations where indicated and properly labeled.
Permethrin is incorporated into scabicide products designed for mite control under medical supervision and regulatory approval.
Permethrin is used in topical treatment protocols where approved concentration, dosing, and safety guidance are followed.

Permethrin is used in outdoor residual treatments on tents, nets, and gear to reduce mosquito and tick exposure.
Permethrin is incorporated into bed nets and protective fabrics in programs aimed at malaria and vector control where approved.
Permethrin is used in camping and field equipment treatments to provide long-lasting insect deterrence.

Permethrin is used in warehouse and storage pest control to manage insects in approved industrial pest management programs.
Permethrin is incorporated into perimeter and spot treatments in food-handling environments only when allowed and with strict compliance controls.
Permethrin is used in transport and logistics pest control to reduce insect infestations in containers and facilities.

Permethrin is used in termite and wood-insect control products in some regions where Permethrin formulations are approved for structural use.
Permethrin is incorporated into anti-insect wood and surface treatments to reduce reinfestation in compatible systems.
Permethrin is used in pest-control service applications where professional labeling and application practices are followed.

Permethrin is used in integrated pest management (IPM) as a chemical tool combined with sanitation, exclusion, and monitoring.
Permethrin is incorporated into rotation programs to manage resistance development and maintain efficacy.
Permethrin is used in targeted treatments to reduce overall pesticide load while achieving effective pest control.

Permethrin is used in research and laboratory settings to evaluate insecticide susceptibility and resistance mechanisms.
Permethrin is incorporated into bioassays and efficacy testing protocols for vector control studies.
Permethrin is valued because Permethrin provides strong broad-spectrum insect control and long-lasting residual performance when used responsibly and according to regulations.

DESCRIPTION


Permethrin is a synthetic pyrethroid insecticide modeled after natural pyrethrins.
Permethrin acts on insect nervous systems by affecting voltage-gated sodium channels.
Permethrin produces knockdown and residual insecticidal activity on treated surfaces.

Permethrin is typically supplied as a technical active and formulated into emulsifiable concentrates, sprays, and other product types.
Permethrin is often present as a mixture of cis and trans isomers that influence performance characteristics.
Permethrin is lipophilic and tends to bind to organic matter and surfaces rather than remain in water.

Permethrin shows strong activity against many insects and some arthropods, including mosquitoes, ticks, and lice.
Permethrin efficacy depends on target species, exposure time, and application surface characteristics.
Permethrin performance can be reduced by insecticide resistance in some pest populations.

Permethrin is generally more stable than natural pyrethrins but can degrade under strong sunlight and environmental stress.
Permethrin persistence varies with formulation type, surface porosity, and weathering conditions.
Permethrin can be toxic to aquatic organisms, so environmental precautions are important in use programs.

Permethrin can be irritating with improper exposure, so handling requires appropriate protective measures.
Permethrin products should be used only according to the approved label and local regulations.
Permethrin is regulated differently across countries for agricultural, veterinary, and human medicinal uses.

Permethrin is used in some human topical medicines at controlled doses for specific parasitic infestations.
Permethrin should not be confused with general-purpose pesticide concentrates intended for non-medical use.
Permethrin safety depends strongly on the formulation, route of exposure, and correct use conditions.

Permethrin should be stored in tightly closed containers away from heat and direct sunlight.
Permethrin formulations may separate over time and require controlled storage to maintain uniformity.
Permethrin quality specifications commonly include assay, isomer ratio, impurity profile, and stability parameters.

Permethrin is a synthetic pyrethroid insecticide widely used for control of insects such as mosquitoes, flies, lice, ticks, and mites, and Permethrin is used in public health, veterinary, textile, and household pest control applications.
Permethrin acts on insect nervous systems by affecting sodium channel function, leading to paralysis and death in susceptible pests, and Permethrin is valued for strong efficacy at low use levels and broad-spectrum activity.
Permethrin use requires careful compliance with local regulations, appropriate labeling, and safe handling practices, because Permethrin can be harmful to aquatic life and is highly toxic to cats, and Permethrin concentrates can irritate skin and eyes.

Permethrin is a lipophilic synthetic pyrethroid typically supplied as a viscous liquid or as formulated concentrates and emulsions, and Permethrin consists of cis and trans isomers whose ratio can influence performance.
Permethrin acts on voltage-gated sodium channels in insects, causing prolonged nerve excitation and paralysis, which results in insect knockdown and mortality.
Permethrin has low water solubility, so Permethrin is commonly formulated as emulsifiable concentrates, microemulsions, suspension concentrates, or treated materials to ensure effective delivery.

Permethrin provides residual activity on treated surfaces, and this makes Permethrin useful for barrier sprays, textile treatments, and long-lasting vector-control products.
Permethrin can be hazardous to aquatic organisms, and Permethrin should not be allowed to enter waterways, drains, or aquatic habitats during use or disposal.
Permethrin is highly toxic to cats, so cat exposure to Permethrin-treated products not intended for cats must be prevented and veterinary guidance should be followed.

Permethrin should be stored in tightly closed containers in a cool, dry, well-ventilated area away from heat and ignition sources.
Permethrin should be handled with appropriate PPE to prevent skin and eye contact, and application must follow label directions and local regulatory requirements.
Permethrin products must be used only as registered, labeled formulations, and Permethrin concentrations and application methods must match the approved use.

PROPERTIES


Chemical Formula: C21H20Cl2O3
Molecular Weight: 391.29 g/mol
Common Name: Permethrin
Chemical Type: Synthetic pyrethroid insecticide
Appearance: Colorless to pale yellow liquid (technical); formulation dependent
Odor: Mild characteristic odor (formulation dependent)
Solubility: Practically insoluble in water; soluble in many organic solvents
Vapor Pressure: Low (reduced volatility; typical)
LogP: High (lipophilic; typical)
Isomer Ratio: Cis/trans ratio varies by grade (common ratios used for different applications)
Stability: Stable under normal storage; degrades with strong UV exposure and extreme conditions
Environmental Hazard: Highly toxic to aquatic life; avoid releases to water environments
Storage Temperature: 15–25°C, tightly closed, away from heat and direct sunlight
Shelf Life: Typically 24–36 months in original sealed packaging (supplier dependent)

FIRST AID


Inhalation:
Move to fresh air if vapors, aerosols, or mists are inhaled.
Seek medical attention if respiratory symptoms develop or persist.
Keep the exposed person warm and at rest.

Skin Contact:
Remove contaminated clothing and wash skin with soap and water.
Seek medical advice if irritation persists or if significant exposure occurred.
Wash contaminated clothing before reuse.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention promptly if irritation persists.

Ingestion:
Rinse mouth with water and do not induce vomiting unless directed by medical personnel.
Seek medical attention immediately, especially for concentrated product exposure.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
Consider aspiration risk if hydrocarbon solvents are present in the formulation.
Monitor for neurologic symptoms and provide supportive care.

HANDLING AND STORAGE


Handling:
Use appropriate PPE including chemical-resistant gloves, safety glasses or goggles, and protective clothing as required.
Avoid inhalation of mists and avoid skin and eye contact, especially with concentrates.
Follow label instructions, approved application rates, and local regulatory requirements.

Ventilation:
Use local exhaust or general ventilation in mixing and handling areas.
Avoid aerosol formation in enclosed spaces without proper ventilation.
Use respiratory protection if required by exposure assessment and product labeling.

Storage:
Store in original tightly closed containers in a cool, dry, well-ventilated place.
Keep away from heat, sparks, open flames, and strong oxidizers.
Store locked up and out of reach of children and unauthorized persons.

Spill and Leak Procedures:
Contain spills and prevent entry into drains, soil, and waterways.
Absorb with inert material and collect into suitable containers for disposal according to regulations.
Wash spill area with detergent solution and collect washings if required by local rules.

Handling Precautions:
Keep Permethrin away from cats and do not use dog-only products on cats or in cat-accessible areas unless explicitly labeled safe.
Avoid contamination of aquariums, ponds, and aquatic habitats and remove pets from treated areas as directed by the label.
Dispose of empty containers and unused product according to local hazardous waste and pesticide disposal regulations.


 

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