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Phenoxypropanol, also known as 2-Phenoxypropanol, is a colorless liquid with a faint floral odor that is soluble in water, alcohol, and many oils.
Phenoxypropanol is a chiral chemical compound from the group of glycol ethers .
Phenoxypropanol is nontoxic and environmental and has remarkable impacts on reducing the VOC of the coatings.
CAS Number: 130879-97-9
Molecular Formula: C9H12O2
Molecular Weight: 152.19
EINECS Number: 212-222-7
Synonyms: 2-Phenoxypropanol, 4169-04-4, 2-phenoxypropan-1-ol, 2-Phenoxy-1-propanol, 1-PROPANOL, 2-PHENOXY-, 2-Phenoxypropyl alcohol, DTXSID7029665, 716K0675WC, DTXCID909665, 2-PHENOXYPROPANOL, (+/-)-, MFCD00142958, (-)-2-Phenoxypropanol, SCHEMBL120055, CHEMBL3186734, UNII-716K0675WC, CHEBI:229364, Propylene Glycol 2-Monophenyl Ether, Tox21_200782, AKOS022299936, PROPYLENE GLYCOL MONOPHENYL ETHER, NCGC00248831-01, NCGC00258336-01, AS-47960, CAS-4169-04-4, DB-268607, CS-0213244, NS00019723, NS00083490, P1111, F17120, 224-027-4, (+/-)-1-PHENOXYPROPAN-2-OL;1-PHENOXYPROPAN-2-OL;PROPYLENE GLYCOL MONOPHENYL ETHER;PROPYLENE PHENOXYTOL;PROPYLENE GLYCOL 1-MONOPHENYL ETHER;PHENOXY PROPANOL;(S)-1-Phenoxy-2-Propanol;AURORA KA-7000
Phenoxypropanol has a shelf life of almost 2 years.
Phenoxypropanol is an organic compound commonly used as a solvent, preservative, and antimicrobial agent in various industries, especially in cosmetics and personal care products.
Phenoxypropanol is a type of alcohol with a phenoxy group (C6H5O) attached to a propanol molecule, giving it both hydrophobic and hydrophilic properties, which makes it effective in formulations where water and oil need to be combined.
This chemical, which is often referred to as 2-Phenoxypropanol, is typically used to prevent the growth of bacteria and fungi in cosmetic products, helping to prolong their shelf life and maintain safety for consumers.
Phenoxypropanol, a gycol ether, can be synthesized by reacting propylene oxide with phenol in the presence of Al2O3- MgO/Fe3O4 catalyst.
In addition to its use in personal care items, phenoxypropanol also finds applications as a solvent in paints, coatings, and cleaning agents, where it aids in dissolving other chemicals and improving the performance of these products.
Phenoxypropanol is considered a safer alternative to other preservatives, such as parabens, in skincare formulations, due to its lower irritation potential.
However, like many chemicals, it must be used within regulated limits to ensure safety, as excessive concentrations may cause skin irritation or allergic reactions in some individuals.
The compound's pleasant odor and ability to dissolve other ingredients make it a valuable ingredient in a wide range of formulations, including lotions, shampoos, deodorants, and even household cleaning products.
This versatile compound is primarily utilized for its preservative properties, as it inhibits the growth of bacteria, fungi, and other microorganisms.
This makes it an essential ingredient in the formulation of cosmetics, toiletries, and personal care products like lotions, shampoos, and deodorants, where the prevention of microbial contamination is crucial to maintaining product stability and safety.
Beyond its antimicrobial role, phenoxypropanol is also used as a solvent, helping to dissolve and stabilize other ingredients within cosmetic and pharmaceutical formulations.
Phenoxypropanol is particularly useful in emulsions, where it ensures that both oil and water components mix evenly, improving the overall texture and performance of the product.
Additionally, its ability to enhance the penetration of active ingredients into the skin makes it an important component in anti-aging, moisturizing, and skin-conditioning products.
Phenoxypropanol is a strong solvent for alkyd resin, epoxy resin, acrylic resin, etc.
Phenoxypropanol can provide excellent ow and leveling, luster, while helping prevent coating defects such as pinholing, orange peel cracking and popping because of its high boiling point, good miscibility, moderate evaporation rate, good coalescing and coupling ability.
Phenoxypropanol or 2-phenoxypropanol is a clear, colourless and odourless liquid with 20 APHA Max and a pH value of 7 to 8 approximately.
Phenoxypropanol is a yellowish, hydrophobic liquid.
When propylene glycol-1-phenylether is mentioned in this article or in the scientic literature without a prex , the 1: 1 mixture (racemate) of ( R ) -propylene glycol-1 Phenoxypropanol and ( S ) -propylene glycol-1 is meant phenyl ether.
Propylene glycol 1-phenyl ether is obtained by reacting propylene oxide and phenol.
Melting point: 11 °C
Boiling point: 243 °C(lit.)
Density: 1.064 g/mL at 20 °C(lit.)
refractive index: n20/D 1.523(lit.)
Flash point: >230 °F
pka: 14.43±0.20(Predicted)
Phenoxypropanol has been used as an additive to saline to induce anesthetic eect on the peripheral tissues isolated from Biomphalaria alexandrina prior to xation.
Phenoxypropanol has wide applications as optical brighteners, pigments and dyestus.
Phenoxypropanol is a solvent for various applications, an intermediate product, formulation additive and additive for coatings, cleaning agents and metal working oil.
Phenoxypropanol is used in cosmetic products as a preservative and solvent and occurs as an active enhancer in disinfectants.
Propylene glycol phenyl ether is a slow-evaporating, very hydrophobic glycol ether ideal in coalescing and carrier solvent applications.
Phenoxypropanol is also used in the manufacturing of pharmaceutical agents, polymer auxiliaries, technical liquids and solvents for polymers.
Phenoxypropanol is one of the main ingredients in the manufacturing of rubber and latex, plastic and rubber polymers, specialities and organic solvents.
Phenoxypropanol is mainly used as a preservative and solvent in various products.
Phenoxypropanol is used as the main ingredient in the manufacturing of aromatic chemicals, preservatives, disperse dye intermediaries, and ethoxylates.
Phenoxypropanol has been used as an additive to saline to induce anesthetic eect on the peripheral tissues isolated from Biomphalaria alexandrina prior to xation.
Phenoxypropanol is widely used in top-grade automobile coatings,automobile repair coatings, electrophoresis coatings, shipping and container coatings, architecture coatings, furnature coatings.
Phenoxypropanol is used as protective agent in printing ink, paint remover, adhesives, insulated materials, cleaning agent, perfumes for soap and cosmetics, coupling agent for dissolving of dye.
Phenoxypropanol is carrier solvent for textile dyes.
Phenoxypropanol is solvent for inks in ball point and felt tip pens, stamp pads, and textile printing pastes.
Phenoxypropanol is coalescent for latex adhesives.
Phenoxypropanol is useful in the formulation of homogeneous, stable metalworking uids.
Phenoxypropanol is used in paint removers.
Phenoxypropanol is used for latex coalescent in water-based architectural and industrial coatings.
Phenoxypropanol is applied in cleaning products, paint formulations, and coatings due to its solvent properties, which enable it to dissolve a wide variety of substances.
Its low toxicity and skin irritation potential compared to other solvents have made it a preferred choice in these applications.
While it is considered a safer alternative to some other preservatives, it is still important for manufacturers to use phenoxypropanol within recommended concentrations, as higher amounts may cause irritation, especially in sensitive skin types.
Regulatory agencies like the FDA and the European Medicines Agency have set guidelines on safe usage levels to ensure that products containing phenoxypropanol remain safe for consumers.
Phenoxypropanol is used as a solvent and paint ( coalescing agent ).
High-boiling solvent, bactericidal agent, xa- tive for soaps and perfumes, intermediate for plas- ticizers.
Phenoxypropanol is a slow evaporating, very hydrophobic glycol ether — more hydrophobic than would be expected based simply on its molecular weight.
Phenoxypropanol is an excellent match for phenolic coatings and linings
Phenoxypropanol is also an excellent coalescent for acrylic-based latexes.
Phenoxypropanol is also used extensively in dyeing applications, where
Phenoxypropanol can function as both a dye solubilizer and as a dye carrier.
Phenoxypropanol has superior viscosity reduction properties in metalworking uids.
Uses Of Phenoxypropanol:
Phenoxypropanol is also widely used in household and industrial cleaning products due to its solvent and antimicrobial properties.
In this context, it helps enhance the cleaning power of surface disinfectants, degreasers, and multipurpose cleaners, ensuring that they effectively eliminate bacteria, fungi, and other pathogens from surfaces.
Its ability to dissolve oils, grease, and other difficult-to-remove substances makes it an ideal component for formulations designed to clean kitchen appliances, countertops, and industrial machinery.
In addition, phenoxypropanol finds use in the formulation of paint and coating products, where it helps improve the uniformity and application of the product.
Its role as a solvent aids in dissolving pigments and resins, ensuring that the paint or coating spreads evenly and adheres properly to surfaces.
This is particularly useful in products like varnishes, lacquers, and wood finishes, where a smooth and even finish is critical.
Furthermore, its low evaporation rate and ability to improve the performance of the product contribute to longer-lasting and more durable coatings.
In the realm of pharmaceuticals, phenoxypropanol can be found in both topical and oral formulations.
In topical products, Phenoxypropanol helps stabilize other ingredients and enhance the overall efficacy of the formulation, often in over-the-counter treatments for skin conditions such as acne or dermatitis.
Phenoxypropanol is also used in some oral products, such as cough syrups and lozenges, where it serves as a flavoring agent or helps improve the solubility of active pharmaceutical ingredients.
Furthermore, its ability to enhance the absorption of other substances into the skin makes phenoxypropanol a useful ingredient in transdermal drug delivery systems.
These systems are designed to deliver medications through the skin, offering a convenient alternative to oral medications.
By helping the active pharmaceutical ingredients penetrate the skin barrier, phenoxypropanol contributes to the effectiveness of these treatments.
Another important use of phenoxypropanol is in personal care products like deodorants and antiperspirants, where it not only acts as a preservative but also helps maintain the product's texture and stability.
Its inclusion in these products ensures they remain effective at combating odor-causing bacteria while remaining smooth and easy to apply.
Phenoxypropanol is a versatile compound with widespread applications across a variety of industries.
From cosmetics to pharmaceuticals to industrial products, its preservative, solvent, and stabilizing properties make it an essential ingredient in many formulations.
Phenoxypropanol has a wide range of uses, particularly in the cosmetic, personal care, and industrial sectors.
In the beauty and skincare industries, it is primarily used as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in formulations.
This helps extend the shelf life of products such as lotions, shampoos, deodorants, body washes, and facial creams, ensuring they remain safe for consumers to use over time.
Phenoxypropanols antimicrobial properties are especially beneficial in products that contain water, which is prone to microbial contamination.
In addition to its preservative role, phenoxypropanol also acts as a solvent, facilitating the dissolution of other ingredients within a product.
This makes it especially useful in emulsions, where it helps blend water and oil-based components together smoothly.
This functionality enhances the texture, consistency, and overall performance of cosmetic products.
Phenoxypropanol is commonly found in makeup removers, hair care products, and moisturizers, where it aids in creating stable, well-mixed formulations.
Beyond cosmetics, phenoxypropanol is utilized in the pharmaceutical industry, where it can be found in topical preparations and pharmaceutical formulations.
Its ability to dissolve and stabilize other substances is valuable in the development of creams, ointments, and gels.
Additionally, Phenoxypropanol serves as a carrier for active ingredients, improving the delivery of these substances to the skin, making them more effective in treating specific conditions.
Phenoxypropanol also has applications in industrial sectors.
It is employed as a solvent in cleaning products, paints, and coatings, where it helps dissolve and disperse other chemicals.
Its solvent properties make it ideal for use in products that require a smooth, consistent application, such as surface cleaners, degreasers, and even certain types of lubricants.
Furthermore, its low toxicity and skin irritation potential compared to other solvents make it a preferred choice in these applications, especially when working with consumer-facing products.
Safety Profile Of Phenoxypropanol:
Phenoxypropanol may cause irritation if it comes into direct contact with the skin or eyes, especially at higher concentrations.
Symptoms of irritation can include redness, itching, and discomfort.
Prolonged or repeated exposure to the skin could lead to dryness or mild dermatitis.
In more severe cases, it could cause a rash or blistering in sensitive individuals.
Some people may experience an allergic reaction to phenoxypropanol, though this is rare.
Symptoms can include swelling, hives, itching, or difficulty breathing.
Individuals with a known sensitivity to phenoxypropanol or similar compounds should avoid products containing it.
Inhalation of phenoxypropanol vapors, particularly in poorly ventilated areas or during industrial use, could cause respiratory irritation.
Symptoms may include coughing, wheezing, or difficulty breathing.
Phenoxypropanol is essential to use proper ventilation or protective equipment in environments where phenoxypropanol vapors might be inhaled.
While phenoxypropanol is generally considered to be a low-risk ingredient when used in regulated amounts, it does present some potential hazards if not handled properly or if used in excessive concentrations.
These risks are largely related to skin and eye irritation, as well as potential allergic reactions in sensitive individuals.
