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PHMB - polyhexamethylene biguanide hydrochloride 20% is a broad-spectrum antimicrobial polymer solution widely used for disinfection, preservation, and microbial control in water treatment, personal care, medical, textile, and industrial applications.
PHMB - polyhexamethylene biguanide hydrochloride 20% is effective against bacteria, fungi, algae, and some viruses by disrupting microbial cell membranes and intracellular functions.
PHMB - polyhexamethylene biguanide hydrochloride 20% is valued for its high efficacy at low use levels, long-lasting antimicrobial activity, and relatively low toxicity to humans when used as directed.
CAS Number: 32289-58-0
EC Number: 500-147-3
Molecular Formula: (C₈H₁₈N₅)ₙ·xHCl
Molecular Weight: Polymeric; variable depending on degree of polymerization
Synonyms: PHMB, Polyhexamethylene Biguanide Hydrochloride, Polyhexanide, PHMB 20% Solution, Biguanide Polymer, Antimicrobial Polymer PHMB, PHMB HCl 20%, Polyhexanide 20%, Polyhexamethylene Biguanide Solution 20%, PHMB Aqueous Solution 20%, PHMB Liquid 20%, PHMB Concentrate 20%, PHMB Antimicrobial 20%, PHMB Disinfectant 20%, PHMB Biocide 20%, PHMB Preservative 20%, PHMB Antibacterial Agent 20%, PHMB Antiseptic 20%, PHMB Broad-Spectrum Biocide 20%, PHMB Microbiocide 20%, PHMB Antifungal Agent 20%, PHMB Antiviral Agent 20%, PHMB Sanitizing Agent 20%, PHMB Water Treatment Biocide 20%, PHMB Pool & Spa Biocide 20%, PHMB Industrial Biocide 20%, PHMB Technical Grade 20%, PHMB Industrial Grade 20%, PHMB Pharmaceutical Grade 20%, PHMB Cosmetic Grade 20%, PHMB Personal Care Preservative 20%, PHMB Wound Care Antiseptic 20%, PHMB Medical Disinfectant 20%, PHMB Hospital Disinfectant 20%, PHMB Surface Disinfectant 20%, PHMB Textile Biocide 20%, PHMB Leather Preservative 20%, PHMB Paper Industry Biocide 20%, PHMB Cooling Tower Biocide 20%, PHMB Process Water Biocide 20%, PHMB Biofilm Control Agent 20%, PHMB Odor Control Biocide 20%, PHMB Slime Control Agent 20%, PHMB Antimicrobial Polymer 20%, Polybiguanide Hydrochloride 20%, Polyhexamethylene Biguanide Polymer 20%, Polybiguanide Solution 20%, Biguanide Polymer 20%, Cationic Biguanide Polymer 20%, Polymeric Biguanide 20%, Polyhexanide Preservative 20%, PHMB Preservative Solution 20%, PHMB Cleaning Formulation Biocide 20%, PHMB Detergent Preservative 20%, PHMB Cosmetic Preservative Solution 20%, PHMB Shampoo Preservative 20%
APPLICATIONS
PHMB - polyhexamethylene biguanide hydrochloride 20% is used in water treatment.
PHMB - polyhexamethylene biguanide hydrochloride 20% controls bacteria and algae in swimming pools and spas.
PHMB - polyhexamethylene biguanide hydrochloride 20% provides long-lasting residual disinfection.
PHMB - polyhexamethylene biguanide hydrochloride 20% is applied in personal care products.
PHMB - polyhexamethylene biguanide hydrochloride 20% acts as a preservative in wet wipes and cosmetics.
PHMB - polyhexamethylene biguanide hydrochloride 20% prevents microbial contamination in water-rich formulations.
PHMB - polyhexamethylene biguanide hydrochloride 20% is used in medical and healthcare products.
PHMB - polyhexamethylene biguanide hydrochloride 20% is incorporated into wound care solutions and dressings.
PHMB - polyhexamethylene biguanide hydrochloride 20% provides antimicrobial protection without significant cytotoxicity.
PHMB - polyhexamethylene biguanide hydrochloride 20% is used in textile finishing.
PHMB - polyhexamethylene biguanide hydrochloride 20% imparts antimicrobial properties to fabrics.
PHMB - polyhexamethylene biguanide hydrochloride 20% reduces odor-causing bacteria in textiles.
PHMB - polyhexamethylene biguanide hydrochloride 20% is applied in industrial disinfectants.
PHMB - polyhexamethylene biguanide hydrochloride 20% sanitizes surfaces and equipment.
PHMB - polyhexamethylene biguanide hydrochloride 20% supports hygiene in food-contact and industrial environments.
PHMB - polyhexamethylene biguanide hydrochloride 20% is used in aquaculture and animal care.
PHMB - polyhexamethylene biguanide hydrochloride 20% controls pathogenic microorganisms in water systems.
PHMB - polyhexamethylene biguanide hydrochloride 20% improves biosecurity and water quality.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used as a disinfectant in water treatment systems.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% controls bacterial growth in swimming pools and spas.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% provides long-lasting antimicrobial protection in water circuits.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in wound care products.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% prevents infection in wound dressings and gels.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% supports safe healing by controlling pathogenic microorganisms.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in medical disinfectants.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is effective against gram-positive and gram-negative bacteria.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% reduces microbial contamination on medical surfaces.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in personal care preservatives.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% protects cosmetic formulations from microbial spoilage.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% maintains product safety in water-based cosmetics.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in contact lens cleaning solutions.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% disinfects lenses without causing eye irritation.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% ensures microbial safety in ophthalmic products.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in surface disinfectants.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% provides residual antimicrobial activity on treated surfaces.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% improves hygiene in hospitals and clinics.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in textile treatments.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% imparts antimicrobial properties to fabrics.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% reduces odor-causing bacteria in treated textiles.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in wet wipes.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% ensures effective disinfection in personal hygiene wipes.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% supports gentle yet effective cleansing.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in household disinfectants.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% controls microbial growth on hard surfaces.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% enhances safety in domestic cleaning products.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in industrial sanitation.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% reduces biofilm formation in processing equipment.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% improves hygiene standards in manufacturing facilities.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in veterinary hygiene products.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% prevents infection in animal wound care.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% supports sanitation in animal housing environments.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in air humidifier disinfection.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% prevents microbial growth in humidifier water tanks.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% improves indoor air hygiene indirectly.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is used in antimicrobial coatings.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% provides long-term microbial resistance on coated surfaces.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% enhances durability of hygienic coatings.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% provides residual antimicrobial protection after application.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is less irritating than many traditional disinfectants when used correctly.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is widely used in medical, cosmetic, and industrial hygiene applications.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% should be stored in tightly closed containers away from light.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% must be handled according to safety guidelines due to its biocidal activity.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is valued for its effectiveness, stability, and long-lasting antimicrobial performance.
DESCRIPTION
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is a polymeric biguanide-based antimicrobial agent.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is supplied as an aqueous solution with 20% active content.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% appears as a clear to slightly yellow liquid.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% exhibits broad-spectrum antimicrobial activity.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% is effective at low use concentrations.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% disrupts microbial cell membranes to inhibit growth.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% has low volatility and high stability in aqueous systems.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% remains active over a wide pH range.
PHMB – Polyhexamethylene Biguanide Hydrochloride 20% shows good compatibility with many formulation ingredients.
PHMB - polyhexamethylene biguanide hydrochloride 20% is a clear to slightly yellow aqueous solution.
PHMB - polyhexamethylene biguanide hydrochloride 20% contains cationic biguanide polymer chains.
PHMB - polyhexamethylene biguanide hydrochloride 20% exhibits strong affinity for negatively charged microbial cell membranes.
PHMB - polyhexamethylene biguanide hydrochloride 20% disrupts membrane integrity and causes cell leakage.
PHMB - polyhexamethylene biguanide hydrochloride 20% interferes with microbial metabolic processes.
PHMB - polyhexamethylene biguanide hydrochloride 20% provides rapid and persistent antimicrobial action.
PHMB - polyhexamethylene biguanide hydrochloride 20% is odorless or has a very mild characteristic odor.
PHMB - polyhexamethylene biguanide hydrochloride 20% is non-volatile and stable in aqueous systems.
PHMB - polyhexamethylene biguanide hydrochloride 20% maintains efficacy over a wide pH range.
PHMB - polyhexamethylene biguanide hydrochloride 20% is compatible with many surfactants and formulation components.
PHMB - polyhexamethylene biguanide hydrochloride 20% may be incompatible with strong anionic compounds.
PHMB - polyhexamethylene biguanide hydrochloride 20% should be formulated carefully to maintain activity.
PROPERTIES
Chemical Nature: Cationic polymeric biguanide hydrochloride
Appearance: Clear to slightly yellow liquid
Odor: Odorless or very faint
Active Content: 20% ±1%
Density: ~1.04–1.06 g/cm³ at 20°C
pH: ~5.0–7.0
Solubility in Water: Completely miscible
Solubility in Organic Solvents: Insoluble
Viscosity: Low to moderate (solution dependent)
Thermal Stability: Stable under normal storage temperatures
pH Stability: Effective across pH 4–10
Ionic Character: Strongly cationic
Biocidal Activity: Broad-spectrum antibacterial and antifungal
Residual Activity: Long-lasting due to polymeric nature
Decomposition: Degrades at high temperatures or extreme pH
Storage Temperature: 5–30°C, protected from freezing
FIRST AID
Inhalation:
Move to fresh air if mist is inhaled.
Seek medical attention if respiratory irritation occurs.
Skin Contact:
Wash skin with soap and water.
Remove contaminated clothing.
Eye Contact:
Rinse eyes with water for at least 15 minutes.
Seek medical attention immediately.
Ingestion:
Rinse mouth and drink water.
Do NOT induce vomiting.
Seek medical advice promptly.
Note to Physicians:
Treat symptomatically and monitor for mucosal irritation.
HANDLING AND STORAGE
Handling:
Wear gloves, goggles, and protective clothing.
Avoid contact with eyes and prolonged skin exposure.
Ensure adequate ventilation during handling.
Avoidance:
Avoid mixing with strong anionic surfactants or soaps.
Avoid strong oxidizing agents.
Spill Procedures:
Absorb with inert material and collect for disposal.
Rinse area with water after cleanup.
Storage:
Store in tightly closed containers.
Keep in a cool, dry, well-ventilated place.
Protect from freezing, heat, and direct sunlight.
