PRODUCTS

PIROCTONE OLAMINE COSMETIC GRADE

Piroctone olamine cosmetic grade can be used as anti-dandruff and antipruritic agents on non-washable hair products.
Piroctone olamine cosmetic grade is widely used in hair care products, baths, cosmetics and washing products.
Piroctone olamine cosmetic grade is also being used in many preservative formulations at neutral pH, which is important for sunscreen formulations.

CAS Number: 68890-66-4
EC Number: 272-574-2
Chem/IUPAC Name: 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
Empirical Formula (Hill Notation): C14H23NO2 · C2H7NO
Molecular Formula: C16H30N2O3

SYNONYMS:
Piroctone Olamine, 68890-66-4, Octopirox, Kopirox, Piroctone Ethanolamine, Octopyrox, Piroctoneolamine, Piroctone Ethanolamine Salt, Piroctone Olamine [USAN], UNII-A4V5C6R9FB, EINECS 272-574-2, A4V5C6R9FB, 2-aminoethanol;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one, NSC-759894, Piroctone Ethanolamine Salt (1:1), EC 272-574-2, NSC 759894, Piroctone Olamine (USAN), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt, PIROCTONE OLAMINE (MART.), PIROCTONE OLAMINE [MART.], PIROCTONE OLAMINE (USP-RS), PIROCTONE OLAMINE [USP-RS], 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt, 1-HYDROXY-4-METHYL-6-(2,4,4-TRIMETHYLPENTYL)-2-PYRIDONE MONOETHANOLAMINE, (+/-)-, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one 2-aminoethanol salt, DTXCID2026735, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethan-1-ol (1:1), Allermyl, Keratolux, Octopirox (TN), SCHEMBL2843, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1), 2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compound with 2-aminoethanol (1:1), CHEMBL2107154, BTSZTGGZJQFALU-UHFFFAOYSA-N, AMY40819, BCP29912, HY-B1345, MFCD01690792, s5213, Piroctone Olamine, Analytical Standard, AKOS025149526, CCG-267454, CS-7659, PIROCTONE ETHANOLAMINE [WHO-DD], AS-15254, P2178, D05505, Piroctone Ethanolamine Salt; Octopirox; Kopirox, PIROCTONE ETHANOLAMINE SALT (1:1) [MI], A836281, Q412572, W-104652, 4-methyl-1-oxido-6-(2,4,4-trimethylpentyl)-2-pyridinone, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone Ethanolamine, Piroctone Olamine, United States Pharmacopeia (USP) Reference Standard, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-1,2-dihydropyridin-2-one; 2-aminoethan-1-ol, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt, EcoGard, POOctopirox, Piroctone Olamine, Ethanol, 2-amino-, compd. with 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone (1:1) (9CI), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt, Octopirox, Octopyrox, Piroctone Ethanolamine Salt, Piroctone Olamine, piroctone olamine, 1-hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one-2-aminoethanol (1:1), 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1h)-pyridinoncompd.with2-aminoethanol(1:1), 2(1H)-Pyridinone,1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-,compd.with2-aminoethanol(1:1), 4,4-trimethylpentyl)-1-hydroxy-4-methyl-6-(compd.with2-2(1h)-pyridinon, octopiroxolamine, 1-hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt, Octopirox, Pyridine-amino ethanol

Piroctone olamine cosmetic grade is a preservative also used for its antifungal functions in anti-dandruff shampoos.
Piroctone olamine cosmetic grade (PO) is a potent anti-dandruff ingredient commonly found in hair care products.
Piroctone olamine cosmetic grade, also known as octopirox, exhibits remarkable properties and has become a staple in combating dandruff and other scalp conditions.

Understanding Piroctone olamine cosmetic grade's chemical properties, synthesis methods, functions, usages, market information, and outlook sheds light on its significance in the hair care industry.
Piroctone olamine cosmetic grade is a white to off-white crystalline powder with a very faint odor.

Piroctone olamine cosmetic grade is insoluble in water, mineral oil, and isopropylene; and soluble in ethanol and propylene glycol.
Piroctone olamine cosmetic grade is a remarkably effective anti-dandruff agent, almost nontoxic ingredient for haircare products and clear shampoo.

Piroctone olamine cosmetic grade exhibits low toxicity, low irritation, and excellent efficacy in hair care applications.
In addition, Piroctone olamine cosmetic grade has good pH and thermal stability, solubility in surfactant systems, and good compatibility with other ingredients.

Piroctone olamine cosmetic grade is the only anti-dandruff agent approved for both rinse-off & leave-on products.
In comparison with other popular anti-dandruff agents, Piroctone olamine cosmetic grade is the best cost-performance option.
Piroctone olamine cosmetic grade is also known under the names PO.

Piroctone olamine cosmetic grade is a particular salt that is also known as Octopirox and Piroctone ethanolamine.
Piroctone olamine cosmetic grade is a compound, which is often used to cure fungal infections.
This salt is a hydroxamic acid derivative Piroctone.

One in every three persons suffers from a problem related to their hair.
Whether Piroctone olamine cosmetic grade is for dandruff, loss.

Piroctone olamine cosmetic grade is an anti-dandruff substance with a process of destroying the fungus Pityrosporum Ovale, which is the cause of dandruff on the scalp.
Piroctone olamine cosmetic grade can treat dandruff.

Piroctone olamine cosmetic grade inhibits new dandruff.
Piroctone olamine cosmetic grade can help stop itchy scalp.
Piroctone olamine cosmetic grade is a synthetic ingredient that is used as an anti-dandruff agent in all kinds of hair products.

Shampoos with Piroctone olamine cosmetic grade are very effective in curing dandruff and preventing hair loss.
Piroctone olamine cosmetic grade is a non-toxic cosmetic ingredient, well tolerated by all skin types, even for pregnant women.
Unlike other daily use shampoos, those containing Piroctone olamine cosmetic grade should not be used more than twice a week.

Piroctone olamine cosmetic grade belongs to the class of hydroxypyridone antimycotics.
Piroctone olamine cosmetic grade is the ethanolamine salt of the hydroxamic acid derivative piroctone.
Piroctone olamine cosmetic grade is structurally similar to Ciclopirox and Pyrithione.

Piroctone olamine cosmetic grade is a pyridone derivative, which is known to have bactericidal effects on gram-positive and gram-negative bacteria and fungicidal effects and hence is a component of many cosmetic products such as anti-dandruff shampoo.
Piroctone olamine cosmetic grade is a broad spectrum of microbiocide/microbiostat.

Piroctone olamine cosmetic grade, also known as piroctone ethanolamine, is a compound sometimes used in the treatment of fungal infections.
Piroctone olamine cosmetic grade is known for its bacteriostatic and fungistatic properties specifically working against Pityrosporum ovale, which lives on the skin and is associated with dandruff and other manifestations of flaking on the face and scalp.

Piroctone olamine cosmetic grade also reduced sebum production.
Piroctone olamine cosmetic grade is a synthetic ingredient that is used mainly as a preservative in personal care and cosmetic products.
Shampoos with Piroctone olamine cosmetic grade are very effective in curing dandruff and preventing hair loss.

Piroctone olamine cosmetic grade has anti-fungal properties and appears as a crystalline powder in its raw form that is white or slightly yellow in color.
Further, Piroctone olamine cosmetic grade is slightly soluble in oil and water.

The chemical formula of Piroctone olamine cosmetic grade is C14H23NO2.C2H7NO.
Piroctone olamine cosmetic grade is a broad spectrum of microbiostat, maybe used in formulating antidandruff shampoo, hair keep and hair care, soap, etc.

Piroctone olamine cosmetic grade is a highly effective, non-toxic and non-irritating anti-dandruff agent, which can be widely used in shampoo, hair conditioner and hair conditioner.
Piroctone olamine cosmetic grade is a white or off-white powder or crystalline powder, odorless.

Piroctone olamine cosmetic grade, also known as piroctone ethanolamine, is a compound sometimes used in the treatment of fungal infections, a broad spectrum of microbiocide/microbiostat.
Piroctone olamine cosmetic grade is known for its bacteriostatic and fungistatic properties specifically working against Pityrosporum ovale.

Piroctone olamine cosmetic grade is easily soluble in ethanol, slightly soluble in water.
Piroctone olamine cosmetic grade is with high purity 99% min.
With wide application of Piroctone olamine cosmetic grade in antidandruff agent, preservative, thickening and agent for elimination of body offensive smell.

USES and APPLICATIONS of PIROCTONE OLAMINE COSMETIC GRADE:
Thanks to its antiseptic properties, Piroctone olamine cosmetic grade can be used as an antimicrobial agent, deodorant, or even a preservative.
Thus, Piroctone olamine cosmetic grade is suitable for anti-acne preparations, antiperspirants, and various cosmetic products as a preservative with low toxicity.

Applications of Piroctone olamine cosmetic grade: Bath products, Hair care, and Sunscreens.
Piroctone olamine cosmetic grade is well used as antidandruff agent, preservative, thickening and agent for elimination of body offensive smell.
Piroctone olamine cosmetic grade can be used as anti-dandruff and antipruritic agents on non-washable hair products.

Piroctone olamine cosmetic grade is widely used in hair care products, baths, cosmetics and washing products.
Piroctone olamine cosmetic grade is also being used in many preservative formulations at neutral pH, which is important for sunscreen formulations.

Typical use level of Piroctone olamine cosmetic grade is only 0.05 – 0.2%.
Piroctone olamine cosmetic grade is an anti-dandruff substance with a process of destroying the fungus Pityrosporum Ovale, which is the cause of dandruff on the scalp.

Piroctone olamine cosmetic grade can treat dandruff.
Piroctone olamine cosmetic grade inhibits new dandruff.
Piroctone olamine cosmetic grade can help stop itchy scalp.

Piroctone olamine cosmetic grade can also be used in skin care products.
Piroctone olamine cosmetic grade helps reduce or prevent air inflammation and allergic reactions.
From the research results it was found that after using shampoo that has Piroctone olamine cosmetic grade 0.5% concentration for 6 weeks, dandruff is reduced by up to 81.7%.

This is compared to shampoo with the same 0.5% Zinc Pyrithione concentration for the same duration.
Zinc Pyrithione can reduce dandruff by 68.6%.
Piroctone olamine cosmetic grade affects the viscosity of the shampoo by making the shampoo thicker.

Due to Piroctone olamine cosmetic grade being effective in killing fungi and other germs (broad-spectrum microbiocide/microbiostat), it can help deodorize the body as well.
Piroctone olamine cosmetic grade is used for treatment products and prevention of dandruff.

Piroctone olamine cosmetic grade can be used together with Zinc Pyrithione for maximum dandruff removal efficiency.
Usage of Piroctone olamine cosmetic grade: Facial Care (creams, serums, shaving foams, sunscreens), Body Care (hand creams, sun care products), air Care (anti-dandruff shampoos, conditioners, hair tonics/creams/gels/lotions), and Hygiene (deodorants).

Application Areas of Piroctone olamine cosmetic grade: Anti-dandruff shampoos and scalp care products, Hair care tonics and serums, Facial cleansers and personal care creams, and Foot care and hygiene formulations.
The high quality Piroctone olamine cosmetic grade is an anti-dandruff active ingredient, soothes inflamed scalp and reduces flaking.

Piroctone olamine cosmetic grade has a specific action against Pityrosporum ovale, the agent responsible for the production of dandruff.
The anti-dandruff product containing Piroctone olamine cosmetic grade destroys the fungus infection that is responsible for the dandruff and works against the formation of new dandruff.

Piroctone olamine cosmetic grade makes the scalp stay clean, itch free and prevents the formation of new dandruff.
You become free of all the inconvenience relating to dandruff.
Piroctone olamine cosmetic grade is used as antidandruff agent, preservative, thickening and agent for elimination of body offensive smell.

Piroctone olamine cosmetic grade has anti-fungal as well as anti-dandruff activity making it ideal for a range of products for dry skin.
Use of Piroctone olamine cosmetic grade: For leave-on products the maximum permitted concentration is 0.5% as this ingredient can cause irritation at larger doses.

For rinse-off, Piroctone olamine cosmetic gradecan be added up to 1%.
Dandruff Removal and Itch Relief: Piroctone olamine cosmetic grade is commonly used in hair care products such as shampoos and conditioners as a dandruff remover and itch reliever.

Antiseptic and Bactericidal Effects: Piroctone olamine cosmetic grade has antibacterial and deodorizing properties, making it suitable for use in bath products and other personal care items.

Preservative in Cosmetics: In addition to its anti-fungal and antibacterial properties, Piroctone olamine cosmetic grade also serves as a preservative in cosmetics, helping to extend the shelf life of these products

As a Fungicide: Piroctone olamine cosmetic grade can be used as a fungicide in various settings, such as in agriculture or in the preservation of materials.
In Soap Products: Piroctone olamine cosmetic grade can act as a bactericide in soap, and also provides a thickening effect.

Piroctone olamine cosmetic grade will need stabilising into your shampoo or conditioner base as without that it will separate.
We recommend the use of Piroctone olamine cosmetic grade of a suspending agent to help with this.
Piroctone olamine cosmetic grade works to treat dandruff at the root cause by functioning as a fungicide with specific efficacy against Malassezia.

Application of Piroctone olamine cosmetic grade: Antidandruff agent, preservative, thickening and agent for elimination of body offensive smell.
Piroctone olamine cosmetic grade is mainly used in cosmetic raw materials, detergent raw materials, hair care chemicals, oral care minerals chemicals.

Piroctone olamine cosmetic grade is an anti-dandruff active ingredient, soothes inflamed scalp and reduces flaking.
Piroctone olamine cosmetic grade has a specific action against Pityrosporum ovale, the agent responsible for the production of dandruff.

The anti-dandruff product containing Piroctone olamine cosmetic grade destroys the fungus and works against the formation of new dandruff.
Piroctone olamine cosmetic grade makes the scalp stay clean, itch-free and prevents the formation of new dandruff.

-Examples of use Piroctone olamine cosmetic grade at various levels in various formulas:
*Anti-dandruff Shampoo (anti-dandruff shampoo): 0.5-1.0%
*Anti-dandruff Tonic (injected or applied to the scalp): 0.1-0.2%
Body odor eliminating soap: 0.2-0.5%

-Application of Piroctone olamine cosmetic grade:
*Antidandruff hair keep: 0.1-0.8% active ingredient.
*Antidandruff fixing agent: 0.05-0.2% active ingredients.
*Antidandruff hair emulsion: 0.1-0.3% active ingredients.
*Antidandruff hair supporting: 0.05-0.1% active ingredient.
*Preservative: 0.2-0.5% active ingredient.
*Smell-eliminating agent: 0.2-0.5% active ingredient.
*Smell-eliminating scented soap: 0.2-0.5% active ingredient.

FUNCTIONS AND USAGES OF PIROCTONE OLAMINE COSMETIC GRADE:
In hair care products, Piroctone olamine cosmetic grade serves as an active ingredient to alleviate dandruff, itching, and scalp irritation.
Piroctone olamine cosmetic grade works by inhibiting the growth of Malassezia furfur and reducing the production of scalp oils, thus addressing the root cause of dandruff.
Additionally, Piroctone olamine cosmetic grade has mild antiseptic properties, promoting scalp health and maintaining a balanced microbiome.

MARKET INFORMATION AND OUTLOOK OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade enjoys widespread use in various hair care formulations, including shampoos, conditioners, and scalp treatments.
With the rising demand for effective anti-dandruff solutions, the market for Piroctone olamine cosmetic grade-containing products continues to expand globally.

Piroctone olamine cosmetic grade's proven efficacy, coupled with consumer preference for gentle yet potent ingredients, positions PO for sustained growth in the hair care sector.
As research advances, further innovations in formulation and delivery systems are expected, enhancing the efficacy and versatility of Piroctone olamine cosmetic grade-based products.

FUNCTION OF PIROCTONE OLAMINE COSMETIC GRADE:
*Anti-fungal Properties:
Piroctone olamine cosmetic grade is a pyridine derivative that exhibits potent anti-fungal activity.
Piroctone olamine cosmetic grade is effective against a broad spectrum of fungi, including molds and yeasts.

By penetrating the cell membrane and forming complexes with iron ions, Piroctone olamine cosmetic grade inhibits energy metabolism in mitochondria, thereby inhibiting fungal growth.

FIND OUT MORE, PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade is an ethanolamine salt of the hydroxamic acid derivative piroctone, first synthesized in 1979 by SCHWARZKOPF-HENKEL.
Piroctone olamine cosmetic grade exhibits antifungal, antibacterial, and anti-inflammatory properties.

Piroctone olamine cosmetic grade's spectrum of action includes various Gram-positive and Gram-negative bacteria, yeasts, molds, and fungi.
Among these, Piroctone olamine cosmetic grade is particularly known for reducing the proliferation of Pityrosporum ovale (Malassezia furfur), a unicellular fungus primarily responsible for dandruff production.

This is why Piroctone olamine cosmetic grade is frequently found in shampoos and hair lotions as an anti-dandruff active ingredient, serving as an alternative to commonly used zinc pyrithione.
Piroctone olamine cosmetic grade works by penetrating the fungal cell wall and leading to the formation of molecular complexes with iron.

This then results in the inhibition of fungal energy metabolism.
While Piroctone olamine cosmetic grade is well known for its anti-dandruff effect, it is also ideal for oily scalps by regulating sebum production.

Other studies have also shown Piroctone olamine cosmetic grade's ability to promote hair growth, making it ideal for individuals prone to alopecia.
Finally, Piroctone olamine cosmetic grade can also offer hair conditioning benefits.

DIRECTIONS FOR USE OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade is readily soluble in alcohol or aqueous surfactant solutions (such as your shampoos and conditioners).
Piroctone olamine cosmetic grade needs to be formulated into a base having a final pH of between 5-8.
It is recommended that Piroctone olamine cosmetic grade be avoided if the formula contains nitrosating ingredients.
Examples of nitrosating ingredients are: Proteins, Amines (Triethanolamine), cocamide diethanolamine/monoethanolamine etc.

SYNTHESIS METHODS OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade is synthesized through a multi-step chemical process involving the reaction of 2-amino-1-ethanol with chloroacetic acid, followed by amidation with 2-aminoethanol and subsequent cyclization.
This synthesis route yields high purity Piroctone olamine cosmetic grade suitable for pharmaceutical and cosmetic applications.

WHAT IS PIROCTONE OLAMINE COSMETIC GRADE USED FOR?
Piroctone olamine cosmetic grade is quite beneficial in maintaining cosmetic and personal care products.
Piroctone olamine cosmetic grade can commonly be found in products like shampoos, cleansers, and hair masks.

*Skin care:
Piroctone olamine cosmetic grade can be used to eliminate the bad odor from the surface of the skin.
Piroctone olamine cosmetic grade is a great preservative that helps in keeping skin care products free from bacterial growth

*Hair care:
Piroctone olamine cosmetic grade is one of the most common 'anti-dandruff' ingredients that is added to hair care products.
Piroctone olamine cosmetic grade is also good for preventing hair loss and split ends

*Cosmetic products:
In cosmetic products, Piroctone olamine cosmetic grade makes use of its antifungal properties to keep the products free from unwanted bacterial growth for a longer time.
The addition of Piroctone olamine cosmetic grade improves the quality of the products and makes them last longer

ORIGIN OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade is basically an ethanolamine salt that is derived from Piroctone - which is a derivative of hydroxamic acid.
Piroctone olamine cosmetic grade appears as a crystalline white powder with a faint distinctive odor.

WHAT DOES PIROCTONE OLAMINE COSMETIC GRADE DO IN A FORMULATION?
*Antimicrobial
*Preservative

SAFETY PROFILE OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade is safe for use when added under the recommended percentage usage - 0.1% for rinse-off products and 0.5% for leave-on products.
Piroctone olamine cosmetic grade suits all skin and hair types, however, a patch test should be performed before full application.
Lastly, Piroctone olamine cosmetic grade is not used in organic products because it is a chemical preservative.

ALTERNATIVES OF PIROCTONE OLAMINE COSMETIC GRADE:
*ZINC PYRITHIONE

METHOD OF PRESERVATION OF PIROCTONE OLAMINE COSMETIC GRADE:
Method of Preservation
Piroctone olamine cosmetic grade is sensitive to UV light and can decompose depending on the degree of irradiation.
Store in its original container at room temperature, protected from moisture and light.

FUNCTIONS OF PIROCTONE OLAMINE COSMETIC GRADE:
*Anti-dandruff
*Antiseptic
*Preservative
*Anti-Seborrheic

PRIMARY PROPERTIES OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade destroys the fungus infection that is responsible for the dandruff and works against the formation of new dandruff.
Also, Piroctone olamine cosmetic grade makes the scalp stay clean and itch free.

Piroctone olamine cosmetic grade is a broad-spectrum antifungal and antibacterial ingredient commonly used in personal care and cosmetic formulations.
Piroctone olamine cosmetic grade helps reduce dandruff and maintain scalp health, offering a mild alternative to zinc-based actives.

FUNCTIONS OF PIROCTONE OLAMINE COSMETIC GRADE IN COSMETIC PRODUCTS:
*ANTI-SEBORRHEIC:
Piroctone olamine cosmetic grade prevents seborrhea and/or seborrheic dermatitis or relieves their symptoms; and/or acts against dandruff.

*PRESERVATIVE:
Piroctone olamine cosmetic grade protects cosmetic products from microbial spoilage.

CHEMICAL PROPERTIES OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade is a white, crystalline powder with a molecular formula of C₁₀H₁₅NO₂ and a molar mass of 185.23 g/mol.
Piroctone olamine cosmetic grade is sparingly soluble in water but dissolves well in ethanol and propylene glycol.
Piroctone olamine cosmetic grade exhibits antifungal and antibacterial properties, making it effective against the yeast Malassezia furfur, a common culprit in dandruff formation.

BENEFITS OF PIROCTONE OLAMINE COSMETIC GRADE:
*Very high purity Piroctone olamine cosmetic grade
*Being used often because of its special functions such as thickening, preservation and elimination of body offensive odor.

MIXING METHOD OF PIROCTONE OLAMINE COSMETIC GRADE:
Disperse Piroctone olamine cosmetic grade in water first.
Then mix Piroctone olamine cosmetic grade into the shampoo formula.
Piroctone olamine cosmetic grade will dissolve in detergent.

SOLUBILITY OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade is very soluble in N,N-Dimethylformamide.
Piroctone olamine cosmetic grade is soluble in methanol.

Piroctone olamine cosmetic grade is sparingly soluble in glacial acetic acid.
Piroctone olamine cosmetic grade is very slightly soluble in chloroform.
Piroctone olamine cosmetic grade is practically insoluble in water.

INCI FUNCTIONS OF PIROCTONE OLAMINE COSMETIC GRADE:
*Anti dandruff:
Piroctone olamine cosmetic grade helps fight against dandruff.

*Preservative:
Piroctone olamine cosmetic grade inhibits the development of microorganisms in cosmetic products.

PIROCTONE OLAMINE COSMETIC GRADE IS PRESENT:
This ingredient is present in 0.87% of cosmetics.
*Anti-dandruff shampoo (64.11%)
*Shaving cream (14.29%)
*Shaving gel (11%)
*Men's shampoo (8.82%)
*Fall protection shampoo (5.63%)

PROPERTIES OF PIROCTONE OLAMINE COSMETIC GRADE:
Appearance: white or slightly yellow powder.
Purity (HPLC): ≥99.0%.
Melting point: 130-135°C.
Boiling Point: 344.1°C.
SMILES string: C(CO)NC(C(CC(C)(C)C)C)C=1N(O)C(=O)C=C(C)C1.
InChI = 1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2.
HS ID: 2933399090.

FUNCTIONS OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade is effective antidandruff, antifungal activity, reduce dandruff shedding.
Volume of use: 0.1-1.0% for flushing type products, 0.05-0.2% for non-washing products.
Piroctone olamine cosmetic grade is commonly used in hair care, skin care, sunscreen, and oral care etc.

CHARACTERISTICS OF PIROCTONE OLAMINE COSMETIC GRADE:
Piroctone olamine cosmetic grade's known for its bacteriostatic and fungistatic properties specifically working against Pityrosporum ovale, which lives on the skin and is associated with dandruff and other manifestations of flaking on the face and scalp.
Piroctone olamine cosmetic grade also reduced sebum production.

PIROCTONE OLAMINE COSMETIC GRADE FOR COSMETICS MARKET OUTLOOK:
The global Piroctone olamine cosmetic grade for Cosmetics market size was valued at USD 320 million in 2023.
Piroctone olamine cosmetic grade is expected to reach USD 450 million by 2032, growing at a CAGR of 3.8% from 2024 to 2032.

The growth of this market is primarily driven by increasing consumer awareness about scalp and skin health.
It is also driven by the rising prevalence of dandruff and other fungal infections.
Expanding application areas of Piroctone olamine cosmetic grade in various cosmetic products also contribute to this growth.

The rising consumer awareness regarding personal grooming and hygiene is a significant growth factor for the Piroctone olamine cosmetic grade for Cosmetics market.
With a growing emphasis on maintaining healthy skin and hair, consumers are increasingly seeking out products that contain effective and scientifically-backed ingredients.

Piroctone olamine cosmetic grade, known for its anti-fungal and anti-bacterial properties, is gaining traction as an essential component in various personal care products.
The increasing shift towards preventive skincare, focusing on avoiding issues like dandruff and acne rather than just treating them, further propels the demand for Piroctone olamine cosmetic grade-based cosmetics.

PHYSICAL and CHEMICAL PROPERTIES of PIROCTONE OLAMINE COSMETIC GRADE:
Water Solubility: 0.351 mg/mL
logP: 3.77
logS: -2.8
pKa (Strongest Acidic): 6.87
pKa (Strongest Basic): -6.4
Physiological Charge: -1
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 1
Polar Surface Area: 40.54 Å²

Rotatable Bond Count: 5
Refractivity: 71.81 m³·mol⁻¹
Polarizability: 27.69 Å³
Number of Rings: 1
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: No
MDDR-like Rule: No

Physical State: Solid
Storage: Store at 4°C
Melting Point: 130-136°C
MDL Number: MFCD01690792
Molecular Weight: 298.4267 g/mol
Chemical Formula: C16H30N2O3
Assay: 95.00 to 100.00%
Food Chemicals Codex Listed: No
Boiling Point: 344.10°C at 760.00 mm Hg (estimated)

Vapor Pressure: 0.000004 mmHg at 25.00°C (estimated)
Flash Point: 323.00°F TCC (161.90°C) (estimated)
logP (o/w): 3.696 (estimated)
Soluble in: water, 18.75 mg/L at 25°C (estimated)
Boiling Point: 344.1°C
Melting Point: 130-135°C
pH: 8.5-10.0
Solubility: Slightly soluble in water
Molecular Weight: 298.42 g/mol
Hydrogen Bond Donor Count: 3

Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 5
Topological Polar Surface Area: 86.8Å²
Physical State: Powder
Color: White
Odor: Weak
Melting Point/Freezing Point: 132°C at 1.013 hPa
Initial Boiling Point and Boiling Range: 130-135°C (ECHA)
Flash Point: 161.9°C Pensky-Martens closed cup

Autoignition Temperature: >430°C at 1.013 hPa
pH: 8.5 at 25°C (saturated solution)
Water Solubility: Approximately 0.0298 g/l at 20°C - slightly soluble
Partition Coefficient (n-Octanol/Water): Log Pow: 3.86 at 20.5°C
Vapor Pressure: <0.1 hPa at 20°C
Density: 1.1 g/cm³ at 21.5°C
Relative Density: 1.1 at 21.5°C
Chemical Name: Piroctone ethanolamine
CAS No.: 68890-66-4

EINECS No.: 272-574-2
Molecular Formula: C14H23NO2·C2H7NO
Molecular Weight: 298.4 g/mol
Appearance: White or slightly yellow crystalline powder
Purity (HPLC): ≥99.0%
PH Value (1% aqueous suspension, 20°C): 9.0-10.0
Melting Point (ºC): 133-136°C
Weight Average: 298.427
Monoisotopic: 298.225642834
Chemical Formula: C16H30N2O3

InChI Key: BTSZTGGZJQFALU-UHFFFAOYSA-N
InChI: InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
IUPAC Name: 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-1,2-dihydropyridin-2-one; 2-aminoethan-1-ol
SMILES: NCCO.CC(CC1=CC(C)=CC(=O)N1O)CC(C)(C)C
CAS No.: 68890-66-4
EINECS No.: 272-574-2
Molecular Weight: 298.421
Molecular Formula:C16H30N2O3
Boiling Point(℃):344.1°C at 760 mmHg
Flash Point(℃):161.9°C

FIRST AID MEASURES of PIROCTONE OLAMINE COSMETIC GRADE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of PIROCTONE OLAMINE COSMETIC GRADE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of PIROCTONE OLAMINE COSMETIC GRADE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system

EXPOSURE CONTROLS/PERSONAL PROTECTION of PIROCTONE OLAMINE COSMETIC GRADE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of PIROCTONE OLAMINE COSMETIC GRADE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions.
Tightly closed.
Dry.

STABILITY and REACTIVITY of PIROCTONE OLAMINE COSMETIC GRADE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).