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PLURONIC P 105

CAS NUMBER: 9003-11-6

EC NUMBER: 618-355-0

MOLECULAR FORMULA: C5H10O2

MOLECULAR WEIGHT: 102.13

IUPAC NAME: 2-methyloxirane;oxirane

Pluronic P 105 is a difunctional block copolymer surfactant terminating in primary hydroxyl groups. 
Pluronic P 105 is nonionic surfactant that is 100% active and relatively nontoxic.

Pluronic P 105 is an ethylene oxide and propylene oxide copolymer, versatile emulsifier that provides good o/w emulsion stability excellent wetting and dispersing properties. 
Pluronic P 105 can be used for the following formulation types: capsule suspensions, emulsion concentrates, emulsions (oil and water), microemulsions, suspension concentrates, suspo-emulsions, wettable granules, oil dispersions.

Synperonic Pluronic P 105 is an ethylene oxide/propylene oxide block copolymer. 
This high HLB, water soluble surfactant can be used as an oil in water emulsifier and as a co-emulsifier in blended surfactant systems for a range of industrial applications.
Pluronic P 105 is a lipoprotein secretion inhibitor.

Applications:
-Chemicals manufacture
-Emulsification
-Nonwovens
-Paper chemicals
-Hard and soft surface cleaners
-Defoamers in coatings
-Water treatment
-Lubricant in metal working
-Anti-foaming aid
-Extender for linear
-Cross-linked polyesters
-Polyurethanes


Pluronic P 105 glycol is nonionic 
Pluronic P 105 is used primarily in pharmaceutical formulations as emulsifying or solubilizing agents.

The polyoxyethylene segment is hydrophilic while the polyoxypropylene segment is hydrophobic. 
All of the Pluronic P 105 is chemically similar in composition, differing only in the relative amounts of propylene and ethylene oxides added during manufacture. 

Their physical and surface-active properties vary over a wide range and a number of different types are commercially available;
Pluronic P 105 is  used as emulsifying agents in intravenous fat emulsions, and as solubilizing and stabilizing agents to maintain the clarity of elixirs and syrups. 

Pluronic P 105 may also be used as wetting agents; in ointments, suppository bases, and gels; and as tablet binders and coatings.
Pluronic P 105 has also been used as an emulsifying agent for fluorocarbons used as artificial blood substitutes, and in the preparation of solid-dispersion systems. 

More recently, Pluronic P 105 has found use in drug-delivery systems.
Therapeutically, Pluronic P 105 is administered orally as a wetting agent and stool lubricant in the treatment of constipation

Pluronic P 105 is usually used in combination with a laxative such as danthron. 
Pluronic P 105 may also be used therapeutically as wetting agents in eye-drop formulations, in the treatment of kidney stones, and as skin-wound cleansers.
Pluronic P 105 is used in solutions for contact lens care.

Pluronic P 105 is a non-ionic block linear copolymer that exhibits rheological, anti-thrombotic, anti-inflammatory and cytoprotective activities in a variety of tissue injury models.
Pluronic P 105 consists of two hydrophilic side chains attached to a hydrophobic central core.

Pluronic P 105 has an average molecular weight of 8400 Daltons.
Pluronic P 105 can also be found in over-the-counter (OTC) products such as toothpaste, laxatives, and mouthwash due to its surfactant properties.

Pluronic P 105 can be used in a variety of cosmetic, industrial and pharmaceutical applications.
Pluronic P 105 is a Poloxamer epoxide.

Pluronic P 105 is used as a food additive.
Pluronic P 105 belongs to the Epoxide family.

Pluronic P 105 is compound containing a cyclic ether with three ring atoms (one oxygen and two carbon atoms).
Pluronic P 105 is commonly used as a surfactant in cosmetics for dissolving oily ingredients in water.

Pluronic P 105 is cell membrane stabilizer
Pluronic P 105 is an anti-foaming agent. 

Pluronic P 105 is a low foaming, non­ionic surfactant. 
Pluronic P 105 is a block copolymer in which the central polypropylene glycol group is flanked by two polyethylene glycol groups.

Pluronic P 105 is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. 
Containing two alcohol groups, it is classed as a diol. 
Pluronic P 105 is miscible with a broad range of solvents, including water, acetone, and chloroform. 


OTHER APPLICATIONS: 

*As a solvent for many substances, both natural and synthetic.
*As a humectant (E1520).
*As a freezing point depressant for slurry ice.
*In veterinary medicine as an oral treatment for hyperketonaemia in ruminants.
*In the cosmetics industry, where propylene glycol is very commonly used as a carrier or base for various types of makeup.
*For trapping and preserving insects (including as a DNA preservative).
*For the creation of theatrical smoke and fog in special effects for film and live entertainment. 
So-called 'smoke machines' or 'hazers' vaporize a mixture of propylene glycol and water to create the illusion of smoke. 
While many of these machines use a propylene glycol-based fuel, some use oil. 
Those which use propylene glycol do so in a process that is identical to how electronic cigarettes work; utilizing a heating element to produce a dense vapor. 
The vapor produced by these machines has the aesthetic look and appeal of smoke, but without exposing performers and stage crew to the harms and odors associated with actual smoke.
*As an additive in PCR to reduce the melting temperature of nucleic acids for targeting of GC rich sequences.
*as a surfactant, it is used to prevent water from beading up on objects. 
Pluronic P 105 is used in photography for this purpose to reduce the risk of water spots, or deposits of minerals from water used to process film or paper.


PHYSICAL PROPERTIES: 

-Molecular Weight: 102.13    

-Exact Mass: 102.068079557    

-Monoisotopic Mass: 102.068079557    

-Topological Polar Surface Area: 25.1 Ų    

-Physical Description: Cloudy paste or hazy viscous liquid

-Color: Colorless

-Form: Liquid

-Solubility: Soluble in cold water

-Melting point: 57-61 °C

-Boiling point: >200 °C

-Density: 1.095 g/mL

-Vapor density: >1

-Vapor pressure: <0.3 mm Hg

-Refractive index: n20/D 1.466

-Flash Point: >230 °F

-Storage temperature: 2-8°C


Pluronic P 105 is a difunctional block copolymer surfactant terminating in primary hydroxyl groups. 
Pluronic P 105 is nonionic surfactant that is 100% active and relatively nontoxic.

Pluronic P 105 is an ethylene oxide and propylene oxide copolymer, versatile emulsifier that provides good o/w emulsion stability excellent wetting and dispersing properties. 
Pluronic P 105 can be used for the following formulation types: capsule suspensions, emulsion concentrates, emulsions (oil and water), microemulsions, suspension concentrates, suspo-emulsions, wettable granules, oil dispersions.

Pluronic P 105 glycol is nonionic 
Pluronic P 105 is used primarily in pharmaceutical formulations as emulsifying or solubilizing agents.


CHEMICAL PROPERTIES: 
    
-Hydrogen Bond Donor Count: 0    

-Hydrogen Bond Acceptor Count: 2    

-Rotatable Bond Count: 0

-Heavy Atom Count: 7    

-Formal Charge: 0    

-Complexity: 36.7    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 1    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 2    

-Compound Is Canonicalized: Yes

-Chemical Classes: Plastics & Rubber -> Polymers


Pluronic P 105 is used as emulsifying agents in intravenous fat emulsions, and as solubilizing and stabilizing agents to maintain the clarity of elixirs and syrups. 
Pluronic P 105 has also been used as an emulsifying agent for fluorocarbons used as artificial blood substitutes, and in the preparation of solid-dispersion systems. 
Pluronic P 105 is usually used in combination with a laxative such as danthron. 

Pluronic P 105 is used in solutions for contact lens care.
Pluronic P 105 is a non-ionic block linear copolymer that exhibits rheological, anti-thrombotic, anti-inflammatory and cytoprotective activities in a variety of tissue injury models.

Pluronic P 105 can be used in a variety of cosmetic, industrial and pharmaceutical applications.
Pluronic P 105 is a Poloxamer epoxide.

Pluronic P 105 is used as a food additive.
Pluronic P 105 belongs to the Epoxide family.

Pluronic P 105 is commonly used as a surfactant in cosmetics for dissolving oily ingredients in water.
Pluronic P 105 is an anti-foaming agent. 

Pluronic P 105 is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. 
Pluronic P 105 is used in photography for this purpose to reduce the risk of water spots, or deposits of minerals from water used to process film or paper.


SYNONYMS: 

Pluronic P 105
Poloxalene
Poloxamer 188
9003-11-6
Poloxamer 407
Pluronic F-68
106392-12-5
2-methyloxirane;oxirane
TERGITOL(TM)XH(NONIONIC)
Pluronic L
Pluronic L 122
Polyethylene-polypropylene glycol
Pluronic
Polyethylene oxide-polypropylene oxide
Polyethylene glycol, propoxylated
Poloxalene L64
Glycols, polyethylene-polypropylene
Emkalyx L 101
Oxirane, methyl-, polymer with oxirane
Polylon 13-5
oxirane-propylene oxide
Teric PE 61
Teric PE 62
Laprol 1502
Pluriol PE 6810
Voranol P 2001
Monolan 8000E80
Niax LG 56
Tergitol XH (nonionic)
Thanol E 4003
Eban 710
Epan 750
Synperonic PE 30/40
Pluronic F87-A7850
Methyloxirane-oxirane polymer
Oxirane-methyloxirane polymer
Pluronic l62(mw 2500)
Pluronic l64(mw 2900)
ethylene oxide propylene oxide
Oxirane, polymer with oxirane
Methyloxirane-oxirane copolymer
Polyethylene-Pluronic L-62LF
Propylene Oxide Ethylene Oxide
Polyoxyethylene polyoxypropylene
Polyoxyethylene-polyoxypropylene
Oligoether L-1502-2-30
Polypropylene glycol, ethoxylated
Glycols, polyethylenepolypropylene
Oxirane, polymer with methyloxirane
Peg/ppg-24/34 triblock copolymer
Poly(propylene oxide-ethylene oxide)
Polyoxyethylenated poly(oxypropylene)
Poly(mixed ethylene, propylene)glycol
Propylene oxide-ethylene oxide polymer
Polyoxyethylene-polyoxypropylene polymer
Ethylene glycol-propylene glycol polymer
Ethylene oxide-propylene oxide copolymer
Propylene oxide-ethylene oxide copolymer
SK & F 18,667
Poly(oxyethylene)-poly(oxypropylene) glycol
N 480
Poly(oxyethylene)-poly(oxypropylene) polymer
Polypropylene glycol-ethylene oxide copolymer
Propane-1,2-diol, ethoxylated, propoxylated
D01941
D10680
Polyethylene oxide-polypropylene oxide copolymer
Polypropoxylated, polyethoxylated propylene glycol
1,2-Propyleneglycol, ethoxylated and propoxylated
M 90/20
75H90000
Propylene glycol, propylene oxide, ethylene oxide polymer
Oxirane, 2-methyl-, polymer with oxirane, ether with 1,2-propanediol (2:1)
.alpha.-Hydro-.omega.-hydroxypoly(oxyethylene)poly(oxypropylene)poly(oxyethylene) block copolymer
f98
PEOPO
rc102
PLURONIC
Poloxamer
75-h-1400
9003-11-6
poloxalene
poloxalkol
Poloxanlene
pluronicf98
POLYOXALKOL
PEG-PPG-PEG
PLURONICL31
PPG-PEG-PPG
Lutrol? F68
Ploxamer 407
PLURONICL122
POLOXAMER213
PLURONIC31R1
PLURONIC17R1
PLURONIC17RL
PLURONIC F87
PLURONIC L108
PLURONIC L-81
POLOXAMER 124
POLOXAMER 181
POLOXAMER 182
POLOXAMER 184
POLOXAMER 188
POLOXAMER 237
POLOXAMER 331
POLOXAMER 338
POLOXAMER 407
ucon75-h-1400
PLURONIC F-68
UCON50-H-5100
UCON75-H-9500
proxanoltsl-3
Pluronic L 35
Pluronic L 42
Pluronic L 43
Pluronic L 63
Thanol E 4003
Contex W18000
Contex W55000
Lutrol? F 127
Pluronic? 10R5
Pluronic? 17R4
synperonic CAS
PLURONIC F-127
SYNPERONIC P 85
PLURONIC(R) F68
PLURONIC(R) L44
PLURONIC(R) L61
PLURONIC(R) L64
Synperonic P 94
Poloxamer188407
Symperonic L 61
Contex W series
PoloxaMer Solid
Poloxanlene 182
Pluronic? L-121
Lμtrol? micro 68
Kolliphor? P 407
Pluronic(R) 31R1
Symperonic F 108
Pluronic(R) 10R5
PoloxaMer 124 NF
Pluronic(R) L-31
Pluronic(R) L-35
Pluronic(R) L-81
Pluronic(R) 17R4
Kolliphor? P 188
UCON75-H-380,000
POLOXAMER 181 NF
POLOXAMER 184 NF
Synperonic P 104
synperonic P 123
Polyetherpolyols
PLURONIC PE 6800
PLURONIC(TM) F68
PLURONIC(TM) F87
PLURONIC(TM) L44
PLURONIC(TM) L61
PLURONIC(TM) L62
PLURONIC(TM) L64
SYNPERONIC F 108
SYNPERONIC L 121
SYNPERONIC L 122
SYNPERONIC P 105
PLURONIC(TM) L101
PLURONIC(TM) L108
PLURONIC(R) F-127
PLURONIC(TM) F127
SYNPERONIC(R) F68
SYNPERONIC(R) L61
SYNPERONIC(R)/L64
Synperonic PE?F68
Synperonic PE?L61
Synperonic PE?L64
Pluronic(R) P-123
Pluronic(R) L-121
Lμtrol? micro 127
Synperonic? PE/P84
Pluracare F 127 NF
POP/POE condensate
Tergitol (TM) L-81
ICIBLOCKCOPOLYMERA
ICIBLOCKCOPOLYMERB
lubricant50-h-5100
SYNPERONIC(R) F108
Poloxalene (500 mg)
Synperonic? PE P105
Synperonic(R) PE/P84
Polyethylene-polypro
Synperonic(R) P 94
SYNPERONIC L61PRACT.
SYNPERONIC F68PRACT.
SYNPERONIC PE(R)/F68
SYNPERONIC PE(R)/L61
synperonic pe(R)/L64
Synperonic(R) P 85
Synperonic(R) L 121
Synperonic(R) PE/L64
Synperonic(R) L 122
Synperonic(R) PE/L61
Synperonic(R) P 104
PLURONICL31SURFACTANT
PLURONICL64SURFACTANT
SYNPERONIC F108PRACT.
Synperonic(R) PE/F68
Poloxamer Solid (1 g)
Lutrol? F-68 solution
Kolliphor? P 407 micro
Kolliphor? P 188 micro
PLURONIC17R1SURFACTANT
2-methyloxirane oxirane
Poloxamer Liquid (1 mL)
Poloxamer(Lutrol-BASF)
Synperonic(R) F68 pract.
Synperonic(R) F108 pract.
Poloxamer 188, micronized
Poloxamer liquid
Poloxamer 407, micronized
Poly(ethyleneglycol)-block
Poloxamer 188 solution
Methyloxirane-oxiranepolymer
polyoxyethylene-oxy-propylene
POLY(ETHYLENEPROPYLENE)GLYCOL
POLYOXYPROPYLENEPOLYOXYETHYLENE
Pluronic(R) 10R5, PPG-PEG-PPG
PEG-PPG-PEG, Pluronic(R) L-81
PEG-PPG-PEG, Pluronic(R) L-35
PEG-PPG-PEG, Pluronic(R) L-61
Pluronic(R) 17R4, PPG-PEG-PPG
PEG-PPG-PEG, Pluronic(R) L-64
PEG-PPG-PEG, Pluronic(R) L-31
PEG-PPG-PEG, Pluronic(R) F-68
methyl-oxiranpolymerwithoxirane
PEG-PPG-PEG [average MW (5800)]
Pluronic(R) 31R1, PPG-PEG-PPG
PEG-PPG-PEG, Pluronic(R) P-123
PEG-PPG-PEG, Pluronic(R) F-108
Synperonic(R) PE P105 surfactant
Polymerofmethyloxiraneandoxirane
PEG-PPG-PEG, Pluronic(R) L-121
POLYETHYLENE-POLYPROPYLENE GLYCOL
glycols,polyethylene-polypropylene
pluronic F-127 cell culture tested
ETHYLENEOXIDE/PROPYLENEOXIDEPOLYMER
ETHYLENEOXIDE-PROPYLENEOXIDEPOLYMERS
ETHYLENEOXIDE-PROPYLENEOXIDECOPOLYMER
2-Methyl-oxirane,polyMer with oxirane
EMbedded sections of polyether F-68
PROPYLENEGLYCOL-ETHYLENEOXIDECOPOLYMER
Oxirane, methyl-, polymer with oxirane
ETHYLENEOXIDE-PROPYLENEOXIDECOPOLYMERS
PROPYLENEOXIDE-ETHYLENEOXIDECOPOLYMERS
POLY(ETHYLENE OXIDE-B-PROPYLENE OXIDE)
POLY(ETHYLENE GLYCOL-CO-PROPYLENEOXIDE)
pluronic F-68 plant cell culture tested
Polymer(ethylene oxide·propylene oxide)
glycols,polyethylene-polypropylene,rc102
ETHYLENEOXIDE-PROPYLENEOXIDEBLOCKPOLYMER
POLY(ETHYLENE GLYCOL)-BLOCK-POLY-(PROPYL
POLY(OXYETHYLENE)POLY(OXYPROPYLENE)GLYCOL
POLY(ETHYLENE GLYCOL-CO-PROPYLENE GLYCOL)
Synperonic(R) F 108 surfactant, non-ionic
polyoxypropylene oxyethyleneglycerol ether
Poly(ethylene glycol-ran-propylene glycol)
polypropylene/ polyethylene glycol copolymer
POLYOXYPROPYLENE-POLYOXYETHYLENEBLOCKCOPOLYMERS
POLYOXYETHYLENE/POLOXYPROPYLENELINEARCOPOLYMERS
POLYOXYPROPYLENEPOLYOXYETHYLENE BLOCK COPOLYMER
pluronic F-68 solution (10%)
polyoxyethylene-polyoxypropylene block copolymer
POLYOXYETHYLENE/POLYOXYPROPYLENELINEARCOPOLYMERS
Pluronic F-127[R] Trade Mark of BASF 
poly(ethylene glycol)-B-poly(propylene glycol)-B-
poly(propylene glycol)-B-poly(ethylene gly-col)-
Polypropylene-polyethylene glycol: (Pluronic L-81)
PLURONIC F-68 SOLUTION
PLURONIC F-127
POLYETHYLENE OXIDE-POLYPROPYLENE OXIDE BLOCK COPOLYMER
POLYETHYLENEGLYCOL/POLYPROPYLENEGLYCOL,MIXEDCOPOLYMERS
BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL
PluronicF-68,Polyoxyethylene-polyoxypropylene block copolymer
Oxirane, 2-methyl-, polymer with oxirane, ether with 1,2-propanediol (2:1)
POLY(ETHYLENE GLYCOL)-BLOCK-POLY(PROPYLENE GLYCOL)-BLOCK-POLY(ETHYLENE GLYCOL)
POLY(ETHYLENE GLYCOL)-B-POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLYCOL) MN2900
POLY(ETHYLENE GLYCOL)-B-POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLYCOL) MN5800
POLY(ETHYLENE GLYCOL)-B-POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLYCOL) MN8400
POLY(ETHYLENE GLYCOL)-B-POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLYCOL) MN1900
POLY(ETHYLENE GLYCOL)-B-POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLYCOL) MN2000
POLY(ETHYLENE GLYCOL)-B-POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLYCOL) MN2800
POLY(ETHYLENE GLYCOL)-B-POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLYCOL) MN4400
POLY(ETHYLENE GLYCOL)-B-POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLYCOL) MN1100
POLY(PROPYLENE GLYCOL)-BLOCK-POLY(ETHYLENE GLYCOL)-BLOCK-POLY(PROPYLENE GLYCOL)
POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLY-COL)-B-POLY(PROPYLENE GLYCOL) MN 330
POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLY-COL)-B-POLY(PROPYLENE GLYCOL) MN 270
POLY(PROPYLENE GLYCOL)-B-POLY(ETHYLENE GLY-COL)-B-POLY(PROPYLENE GLYCOL) MN 200
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) 
 

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