POLOXAMINE 1107 (TETRONIC 1107)

Poloxamine 1107, also known as Tetronic 1107, is a block copolymer that serves as a surfactant, emulsifier, and dispersant in various formulations.
Poloxamine 1107 is used for its multifunctional properties, including stabilization of emulsions, solubilization of hydrophobic compounds, and enhancement of product viscosity.
Poloxamine 1107 is widely applied in pharmaceutical, cosmetic, and industrial applications due to its amphiphilic nature and its ability to interact with both hydrophobic and hydrophilic components.

CAS Number: 9003-11-6
EC Number: 618-353-3
Molecular Formula: Mixture (block copolymer of ethylene oxide and propylene oxide)
Molecular Weight: Approx. 15,000 Da

Synonyms: Tetronic 1107, Poloxamine 1107, Block Copolymer Surfactant, Nonionic Surfactant, Poly(ethylene oxide)-Poly(propylene oxide) Copolymer, Emulsifying Agent, Dispersant

APPLICATIONS

Poloxamine 1107 (Tetronic 1107) is widely used in personal care formulations, including shampoos, conditioners, and body washes, where it acts as an emulsifier and surfactant, improving foam stability and product viscosity.
Poloxamine 1107 (Tetronic 1107) is employed in pharmaceutical formulations for drug delivery systems, where it helps to solubilize poorly soluble drugs and enhances the stability of emulsions and suspensions.
Poloxamine 1107 (Tetronic 1107) is found in topical creams and lotions, where it improves the spreadability of the product while enhancing the absorption of active ingredients through the skin.

Poloxamine 1107 (Tetronic 1107) is utilized in industrial cleaning formulations, where it acts as a detergent and wetting agent, helping to remove oils, dirt, and contaminants from surfaces.
Poloxamine 1107 (Tetronic 1107) is applied in paints and coatings, where it serves as a dispersant for pigments and additives, ensuring uniform distribution and stability of the formulation.
Poloxamine 1107 (Tetronic 1107) is incorporated into agricultural formulations, where it enhances the solubilization and dispersal of active ingredients, improving the effectiveness of pesticides and fertilizers.

Poloxamine 1107 (Tetronic 1107) is essential in emulsion polymerization processes, where it helps to stabilize latex emulsions, ensuring uniform particle size distribution and improving the overall quality of the polymer.
Poloxamine 1107 (Tetronic 1107) is used in water treatment formulations, where it acts as a dispersant, preventing the agglomeration of particles and helping to improve water clarity.
Poloxamine 1107 (Tetronic 1107) is employed in the formulation of oilfield chemicals, where it acts as a surfactant and demulsifier, aiding in the separation of oil and water and improving the efficiency of oil recovery processes.

Poloxamine 1107 (Tetronic 1107) is found in cosmetics, such as facial cleansers and makeup removers, where it helps to dissolve makeup and impurities while being gentle on the skin.
Poloxamine 1107 (Tetronic 1107) is applied in hair dyes and hair treatment formulations, where it enhances the solubility of colorants and improves product performance during application.
Poloxamine 1107 (Tetronic 1107) is used in pharmaceutical emulsions and creams to enhance the solubility of hydrophobic drugs and ensure a consistent product texture and stability.

Poloxamine 1107 (Tetronic 1107) is utilized in biotechnology applications for protein stabilization and the solubilization of biologics, ensuring that active ingredients remain stable throughout the formulation's shelf life.
Poloxamine 1107 (Tetronic 1107) is found in personal care products designed for sensitive skin, where its mild surfactant properties provide gentle cleansing without irritation.
Poloxamine 1107 (Tetronic 1107) is used in disinfectant formulations, where it aids in the dispersal of active antimicrobial agents and enhances their effectiveness in cleaning surfaces.

Poloxamine 1107 (Tetronic 1107) is employed in the formulation of textile treatments, where it acts as a wetting agent, enhancing the penetration of dyes and treatments into fabric fibers.
Poloxamine 1107 (Tetronic 1107) is used in anti-foaming agents, where it helps to control and reduce foam formation in industrial processes such as fermentation, chemical manufacturing, and food processing.
Poloxamine 1107 (Tetronic 1107) is applied in automotive care products, such as car washes and polishes, where it enhances the product's ability to remove dirt and grime while leaving a glossy finish on vehicle surfaces.

DESCRIPTION

Poloxamine 1107 (Tetronic 1107) is a versatile nonionic block copolymer surfactant, known for its ability to stabilize emulsions, enhance solubilization, and improve product viscosity.
Poloxamine 1107 (Tetronic 1107) contains both hydrophilic and hydrophobic segments, making it highly effective in solubilizing and stabilizing hydrophobic compounds in aqueous formulations.
Poloxamine 1107 (Tetronic 1107) is widely used in personal care, pharmaceutical, industrial, and agricultural applications due to its excellent emulsifying, dispersing, and stabilizing properties.

Poloxamine 1107 (Tetronic 1107) is known for its ability to improve the texture, consistency, and performance of formulations, providing smooth, uniform results in emulsions, creams, and gels.
Due to its amphiphilic nature, Poloxamine 1107 (Tetronic 1107) is ideal for formulations that require interaction between hydrophilic and hydrophobic components, such as surfactant-based systems.
Poloxamine 1107 (Tetronic 1107) is widely used in formulations that require controlled release of active ingredients, particularly in pharmaceutical and personal care applications, where it improves bioavailability and product stability.

Poloxamine 1107 (Tetronic 1107) is biodegradable and environmentally friendly, making it suitable for use in eco-friendly and sustainable product formulations.
In industrial applications, Poloxamine 1107 (Tetronic 1107) acts as a dispersant and wetting agent, improving the performance of formulations in harsh environments and enhancing the stability of emulsions.
Poloxamine 1107 (Tetronic 1107) is effective even at low concentrations, making it a cost-effective ingredient for manufacturers across a variety of industries.

PROPERTIES

Chemical Formula: Mixture (block copolymer of ethylene oxide and propylene oxide)
Molecular Weight: Approx. 15,000 Da
Common Name: Poloxamine 1107 (Tetronic 1107)
Appearance: White to off-white powder or viscous liquid
Density: 1.05 g/cm³
Boiling Point: N/A
Melting Point: N/A
Solubility: Soluble in water and alcohols; slightly soluble in oils
Flash Point: >200°C
Reactivity: Stable under normal conditions
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store in a cool, dry place away from direct sunlight and moisture
Vapor Pressure: Low

FIRST AID

Inhalation:
If Poloxamine 1107 (Tetronic 1107) is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation or rash develops, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Poloxamine 1107 (Tetronic 1107) is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.

HANDLING AND STORAGE

Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles when handling large quantities of Poloxamine 1107 (Tetronic 1107).
Use in a well-ventilated area to avoid inhalation of vapors or dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Poloxamine 1107 (Tetronic 1107) to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Poloxamine 1107 (Tetronic 1107).
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Poloxamine 1107 (Tetronic 1107) in a cool, dry, well-ventilated area away from incompatible materials.
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and moisture.

Handling Cautions:
Avoid inhalation of vapors and direct contact with skin and eyes.
Use explosion-proof equipment in areas where vapors may be present.