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POLY(HEXAMETHYLENEBIGUANIDE)

Poly(hexamethylenebiguanide) is best known for its broad-spectrum antimicrobial and antifungal activity.
Poly(hexamethylenebiguanide) is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu).
Poly(hexamethylenebiguanide) is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.

CAS Number: 32289-58-0
Molecular Formula: C10H23N5
Molecular Weight: 213.32312
EINECS Number: 1308068-626-2

Caswell No. 676, Cosmoquil CQ, EPA Pesticide Chemical Code 111801, LS-118083, PHMB, PP 073, Polihexanide [INN], Polihexanido, Polihexanido [INN-Spanish], Polihexanidum, Polihexanidum [INN-Latin], Poly(hexamethylenebiguanide hydrochloride), Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl), hydrochloride, Poly(iminoimidocarbonyl-iminoimidocarbonyl-iminohexamethylene) hydrochloride, Poly(iminoimidocarbonyliminoimidocarbonylimino hexamethylene monohydrochloride), Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene) hydrochloride, Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene), hydrochloride, Polyhexanide, Polymeric biguanide polihexanide, Vantocil 1B

Poly(hexamethylenebiguanide), also known as PHMB, is a polymer compound with antimicrobial properties.
Poly(hexamethylenebiguanide) is commonly used as a disinfectant and preservative in various products such as personal care products, wound care products, contact lens solutions, and swimming pool water treatments.
Poly(hexamethylenebiguanide) works by disrupting the cell membranes of microorganisms, including bacteria, viruses, and fungi, which helps to kill or inhibit their growth.

Poly(hexamethylenebiguanide) is effective against a wide range of microorganisms and is known for its long-lasting antimicrobial activity.
Poly(hexamethylenebiguanide) is a polymer used as a disinfectant and antiseptic. In dermatological use, it is spelled polihexanide (INN) and sold under the names Lavasept, Serasept, Prontosan, and Omnicide.
Poly(hexamethylenebiguanide) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.

Products containing Poly(hexamethylenebiguanide) are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, first aid, surface disinfection, and linen disinfection.
Poly(hexamethylenebiguanide) eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Poly(hexamethylenebiguanide) is sold as a swimming pool and spa disinfectant in place of chlorine or bromine based products under the name Baquacil.

Poly(hexamethylenebiguanide) is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
Poly(hexamethylenebiguanide) is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors.
Poly(hexamethylenebiguanide) hydrochloride salt (solution) is used in the majority of formulations.

Poly(hexamethylenebiguanide) is a broad-spectrum antiseptic which avoids many efficacy and toxicity problems associated with antimicrobials, in particular, it has a low risk of loss of susceptibility due to acquired antimicrobial resistance.
Poly(hexamethylenebiguanide) is an antimicrobial agent, which can be used in medical, apparel, and household textile sectors.
Poly(hexamethylenebiguanide) is a polymer that has antimicrobial and disinfectant properties.

Poly(hexamethylenebiguanide) is synthesized from sodium salts and has been shown to have antibacterial efficacy against a variety of bacteria and viruses in vitro.
Poly(hexamethylenebiguanide) can be used as a model system for benzalkonium chloride or zirconium oxide, which are also antimicrobial agents.
The polymer has also been shown to have pharmacological effects, such as tissue infections in mice.

Poly(hexamethylenebiguanide), serving as an antimicrobial agent, finds applications across various fields including medical, apparel, and household textiles.
Poly(hexamethylenebiguanide) is widely utilized as a disinfectant in personal care commodities like cosmetics and toiletries and as a sanitizer in swimming pools. Poly(hexamethylenebiguanide) possesses marked characteristics of cationic polyelectrolytes. There are also unique determination methods to PHMB-HCl using its ion association with organic anions and polyanion.

Poly(hexamethylenebiguanide) will provide several colloidal titrations and a voltammetric method.
Poly(hexamethylenebiguanide) is a polymer applied as a disinfectant and anti-septic.
In dermatological use, it is also called polihexanide.

Poly(hexamethylenebiguanide) is very effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).
Some products containing Poly(hexamethylenebiguanide) are applied for inter-operative irrigation, both before and after surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.

Poly(hexamethylenebiguanide) eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Another good application of Poly(hexamethylenebiguanide) is that it is widely used as a swimming-pool and spa water sanitizer instead of chlorine- or bromine-based commodities.
Poly(hexamethylenebiguanide) is also utilized as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.

The solution of Poly(hexamethylenebiguanide) is an important ingredient in some pharmaceutical or veterinary formulations.
Poly(hexamethylenebiguanide) is a new environment-friendly cationic water-soluble polymer.
Poly(hexamethylenebiguanide) is a water solution that can be used as a broad-spectrum and high efficiency disinfectant.

Poly(hexamethylenebiguanide) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of its special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.
Poly(hexamethylenebiguanide) is a high molecular polymer, which is easy to be washed away.

Poly(hexamethylenebiguanide) is non-corrosive to the skin, and can not be easily absorbed by human organs.
Vitro studies show that Poly(hexamethylenebiguanide) is non-toxic to human cells. Skin irritancy test of rabbits and human hands shows that PHMB is non-irritant to animal and human skin.
Poly(hexamethylenebiguanide) is a highly effective antimicrobial agent used in various applications such as disinfectants, sanitizers, and preservatives.

With a purity of 98%, Poly(hexamethylenebiguanide) is commonly utilized in the healthcare and personal care industries.
Proper safety measures should be taken when handling this chemical as it can cause skin and eye irritation.
Poly(hexamethylenebiguanide) should be stored in a tightly sealed container in a cool, dry place away from sources of heat or ignition.

Performance data shows that this product conforms to technical grade standards and has no significant environmental impact if handled according to guidelines.
Poly(hexamethylenebiguanide) is a colorless or light yellow transparent liquid, in which the guanidine group has high activity, which can make the polymer into a positive charge, and it is easily attacked by various negatively charged bacteria and bacteria.
The virus is adsorbed, thereby inhibiting the division ability of bacteria and viruses, making them lose their reproductive ability, and the film formed by the polymer blocks the respiratory channels of the microorganisms, causing the microorganisms to die quickly.

Poly(hexamethylenebiguanide) is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, Poly(hexamethylenebiguanide) 2% solution is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.
Poly(hexamethylenebiguanide) is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.

Poly(hexamethylenebiguanide) is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.
As a preservative, Poly(hexamethylenebiguanide) is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Poly(hexamethylenebiguanide) is widely used in environmental disinfection including hospitals, schools, hotels, and public places.

Poly(hexamethylenebiguanide) is a disinfectant with a broad spectrum of inducing cell death by disrupting cell membrane integrity.
Poly(hexamethylenebiguanide) is an environmentally friendly, noncorrosive, and nontoxic to humans and animals.
Poly(hexamethylenebiguanide) is a preservative in cosmetics, personal care products, fabric softeners, contact lens solutions, hand washes, and more.

In cosmetics, Poly(hexamethylenebiguanide) enables the preservation of fruit and vegetables.
Polyhexamethylene biguanide is also used to preserve wet wipes, control odor in textiles, prevent microbial contamination in wound irrigation and sterile dressings; disinfect medical/dental utensils and trays, farm equipment, animal drinking water, and hard surfaces for food handling institutions and hospitals; and to deodorize vacuums and toilets.
Poly(hexamethylenebiguanide) can work at low concentrations with swift action, a broad spectrum of action, and its wide acceptance and exploitation for potential multi-purpose functional use.

Poly(hexamethylenebiguanide) will be promising for advanced environmental treatments, including food disinfection, water disinfection, and surface disinfection, and meet the criteria for an ideal antimicrobial agent.
Poly(hexamethylenebiguanide) is a chemical biocide and a member of the polymeric guanidine family.
Poly(hexamethylenebiguanide) is used as a disinfectant, antiseptic, and general disinfecting agent in the food industry and, very successfully, for the disinfection of swimming pools.

This widely used biocide has been reviewed by the US Environmental Protection Agency (EPA) and noted, except for occupational users, as having a shallow aggregate risk of adverse health effects on the public or environment.
Poly(hexamethylenebiguanide) binds to the negatively charged phosphate head groups of phospholipids at the bacteria cell wall, causing increased rigidity, sinking nonpolar segments into hydrophobic domains, and disrupting the membrane with subsequent cytoplasmic shedding culminating in cell death.

There have been no reported instances of bacteria acquiring resistance to Polyhexamethylene biguanide.
Poly(hexamethylenebiguanide) is well tolerated when used topically on skin, eyes, the ciliated epithelium of the nose, and wounds.
The market for Poly(hexamethylenebiguanide)s, which now include liquids, gels, and antimicrobial dressings, is expanding rapidly.

Poly(hexamethylenebiguanide) is a polymer used as a disinfectant and antiseptic.
Poly(hexamethylenebiguanide) is best known for its broad-spectrum antimicrobial and antifungal activity.
Poly(hexamethylenebiguanide) is part of the same pharmaceutical family as chlorhexidine and is active against many bacteria.

In dermatological use, Poly(hexamethylenebiguanide) is spelled polihexanide (INN) and sold under Lavasept, Serasept, Prontosan, and Omnicide.
Polyhexamethylene biguanide is effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.
Poly(hexamethylenebiguanide) is a new generation of disinfectant with a wide scope of applications in agriculture and food processing plants, logistics, kitchens, transport vehicles.

Poly(hexamethylenebiguanide) is a disinfectant with a broad spectrum of activity against bacteria, viruses and fungi, inducing cell death by disrupting cell membrane integrity and it is used as a preservative in cosmetics, personal care products, fabric softeners, contact lens solutions, hand washes, and more.
In cosmetics, the preservation of fruit and vegetables.
Poly(hexamethylenebiguanide) is also used to preserve wet wipes; to control odor in textiles; to prevent microbial contamination in wound irrigation, sterile dressings; to deodorize vacuums and toilets to disinfect medical/dental utensil and trays, farm equipment, animal drinking water and hard surfaces for food handling institutions and hospitals.

Polyhexamethylene biguanide is used in antimicrobial hand washes, rubs, and air filter treatments as an alternative to ozone.
Polyhexamethylene biguanide is also used as an active ingredient for recreational water treatment and as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.
Poly(hexamethylenebiguanide) has been used in many applications, from swimming pool sanitizers to preservatives in cosmetics and contact lens solutions.

Poly(hexamethylenebiguanide) appears to be available in presentations that provide clinicians with effective wound care modalities for most clinical scenarios and has also been used as a perioperative cleansing agent, in mouthwash, in ophthalmology.
Petrou-Binder describes the germicidal effects of Poly(hexamethylenebiguanide) as eye drops before cataract surgery.
Poly(hexamethylenebiguanide) can be found in swimming pool sanitizers, cosmetics, leather preservatives, contact lens disinfectants, cleansers in agriculture and food handling, in the treatment of hatching eggs, fibers and textiles, and technical fluids like cutting oils and glues.

Poly(hexamethylenebiguanide) is a polymer used as a disinfectant and antiseptic.
In dermatological use Poly(hexamethylenebiguanide) is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, and Omnicide.
Poly(hexamethylenebiguanide) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).

Some products containing Poly(hexamethylenebiguanide) are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.
Branded as Baquacil, Poly(hexamethylenebiguanide) also has an application as a swimming-pool and spa water sanitizer in place of chlorine- or bromine-based products.

storage temp.: Inert atmosphere,Room Temperature
solubility: Water
InChI: InChI=1S/C10H23N5/c1-9(11)14-7-5-3-4-6-8-15-10(12)13-2/h3-8H2,1-2H3,(H2,11,14)(H3,12,13,15)
InChIKey:SAGIGHPRUJPLKX-UHFFFAOYSA-N
SMILES: C(=N)(C)NCCCCCCNC(=N)NC

Poly(hexamethylenebiguanide) is also used as a surface disinfectant and is alleged to be suitable for skin disinfection.
Poly(hexamethylenebiguanide) has a slow effectand does not meet the practical requirementsfor prophylactic antiseptics in this respect.
Although Poly(hexamethylenebiguanide) is somewhat less effective than benzalkonium chloride, it is sometimes used instead of benzalkonium because it is less foamproducing under use conditions.

The preparation method of Poly(hexamethylenebiguanide):By a certain proportion of 1; the own bisguanides of 6-and catalyst join in reaction vessel; under nitrogen protection, said mixture is heated to 80-200 DEGC and reacts, react 2-24 hour; reaction terminates; cooling blowing, obtains poly hexamethylene biguanide, poly hexamethylene biguanide aqueous acid is neutralized to pH value 5-9; and performing filtering so as to obtain a polyhexamethylene biguanidine salt.
Poly(hexamethylenebiguanide) is a cationic polymer with antimicrobial and antiviral properties.
Poly(hexamethylenebiguanide) has been commonly accepted that the antimicrobial activity is due to the ability of PHMB to perforate the bacterial phospholipid membrane leading ultimately to its death.

Poly(hexamethylenebiguanide) is a new environment-friendly cationic water-soluble polymer.
Poly(hexamethylenebiguanide) is a water solution that can be used as a broad spectrum and high efficient disinfectant.
Poly(hexamethylenebiguanide) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.

Because of its special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.
Poly(hexamethylenebiguanide) is odorless and can be easily dissolved in water to form a tasteless colorless transparent solution.
Poly(hexamethylenebiguanide) can be used as a disinfectant for almost all kinds of bacteria.

Poly(hexamethylenebiguanide) is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, PHMB 20% solution is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.
Poly(hexamethylenebiguanide), is a cationic biguanide polymer bioci antimicrobial applications.

Poly(hexamethylenebiguanide) is a substance that controls, prevents, or destroys harmful microorganisms (i.e., bacter fungi) on inanimate objects and surfaces.
Poly(hexamethylenebiguanide) is a disinfectant with a broad spectrum of activity against bacteria, viruses, and fungi.
Poly(hexamethylenebiguanide) is a cationic biocide marketed worldwide due to its excellent antimicrobial activity, chem toxicity, and reasonable cost.

Poly(hexamethylenebiguanide) destroys or irreversibly inactivates most pathogenic microorganisms.
Poly(hexamethylenebiguanide) is a broad-spectrum antiseptic that avoids many efficacy and toxicity problems associat antimicrobials; in particular, it has a low risk of loss of susceptibility due to acquired antimicrobial resistance.
Poly(hexamethylenebiguanide) is used as a sanitizer, bactericide ( antibacterial ), antiseptic, and disinfectant, widely eff positive and negative gram bacteria with applications in surface cleaners, hand cleaners/sanitizing, close to neutral powder de polymers, antimicrobial and dishwashing liquids, and other personal care applications with microbial activity.

20% Aqueous solution of Poly(hexamethylenebiguanide) is used as a biocide, antibacterial, Disinfectant, and Virucidal.
At a 1% to 2% dosage, this can be an adequate replacement for alcohol in your products as a water-based disinfectant.
This is very effective compared to Benzalkonium Chloride.

Poly(hexamethylenebiguanide) is an excellent biocide that is an environmentally friendly product and is expected to be used w to provide valuable disinfection, cleaning, and hygiene functions in a broad type of products such as cosmetics, deodorant, co solutions, fabric softeners, water treatments, wound care products, and antimicrobial foam dressings.
Poly(hexamethylenebiguanide) is expected to be a component of pool cleaners, skin disinfectants, urinary catheter flush solutions, sanitizers in different ap hospital disinfectants, and food and equipment in contact with food.

Poly(hexamethylenebiguanide) is a polymer used as a disinfectant and antiseptic. In dermatological use, it is spelled polihexanide (INN) and sold under the names Lavasept, Serasept, Prontosan, and Omnicide.
Poly(hexamethylenebiguanide) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.
Products containing Poly(hexamethylenebiguanide) are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, first aid, surface disinfection, and linen disinfection.

Poly(hexamethylenebiguanide) eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Poly(hexamethylenebiguanide) is sold as a swimming pool and spa disinfectant in place of chlorine or bromine based products under the name Baquacil.
Poly(hexamethylenebiguanide) is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.

Poly(hexamethylenebiguanide) is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors.
The Poly(hexamethylenebiguanide) salt (solution) is used in the majority of formulations.
Poly(hexamethylenebiguanide) is a highly water soluble and hydrolytically stable polymeric material.

The presence of multiple hydrogen bond and chelation sites within Poly(hexamethylenebiguanide) renders it of potential interest in the field of supramolecular chemistry.
Poly(hexamethylenebiguanide) shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.
Poly(hexamethylenebiguanide) is available also as a solid.

A hydrochloride salt of Poly(hexamethylenebiguanide).
Poly(hexamethylenebiguanide) is a broad spectrum and fast acting bactericide which is used for the formulation of disinfectants and sanitisers.

Uses Of Poly(hexamethylenebiguanide):
Poly(hexamethylenebiguanide) is a polymer used as a disinfectant and antiseptic.
In dermatological use, Poly(hexamethylenebiguanide) is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, Prontosan and Omnicide.
Poly(hexamethylenebiguanide) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).

Poly(hexamethylenebiguanide) can be used as disinfectant, antibacterial, bactericide, mildew-proof, algae-inhibitor, flocculant ,etc.
Widely used in health care, chemicals, textiles, paper, wipes, livestock, aquaculture, fisheries, plastics, agriculture, water treatment and other fields.
Poly(hexamethylenebiguanide) is applied as a sanitizer or preservative to kill bacteria.

Poly(hexamethylenebiguanide) restrains the gram-positive bacterium, gram-negative bacterium, fungus and yeast, and so on.
As a preservative, Poly(hexamethylenebiguanide) is utilized in chemical products like cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and so on.
Poly(hexamethylenebiguanide) is also commonly applied in eviromental disinfection area, such as in hospitals, schools, hotels, and a lot of other public sites.

Fengchen Group is a leading Poly(hexamethylenebiguanide) supplier and manufacturer.
Poly(hexamethylenebiguanide) can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eelis, Aeromonas hydrophilus, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.
Poly(hexamethylenebiguanide) is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceuticals, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, anitary pads, clothes, etc.

Poly(hexamethylenebiguanide) can be widely used in textile, animal husbandry, aquaculture, medical sterilization, and daily disinfectant.
Poly(hexamethylenebiguanide) is used as a sanitizer or preservative to kill bacteria.
Poly(hexamethylenebiguanide) restrains the gram-positive bacterium,gram-negative bacterium, fungus and yeast etc.

As a preservative, Poly(hexamethylenebiguanide) is used in cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and more.
Poly(hexamethylenebiguanide) is also widely used in evironmental disinfection including hospitals, schools, hotels, and public places
Poly(hexamethylenebiguanide) is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.

Poly(hexamethylenebiguanide) is used for disinfection of contact lenses, eye drops, and surgical procedures.
Due to the strong tolerance of the eyes to PHMB.
Poly(hexamethylenebiguanide) can be used as a drug for the treatment of Acanthopanaxa Miba keratitis and the prevention and treatment of other eye diseases.

At the same time, Poly(hexamethylenebiguanide) is also widely used in cosmetics, personal care products, textiles, food industries, etc.
Poly(hexamethylenebiguanide) is a polymer used as a disinfectant and antiseptic, its salt (solution) is used in the majority of formulations.
Poly(hexamethylenebiguanide) eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.

Poly(hexamethylenebiguanide) also has an application as a swimming-pool and spa water sanitizer in place of chlorine- or bromine-based products.
Poly(hexamethylenebiguanide) is used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
Poly(hexamethylenebiguanide) is used in personal care products such as soaps, shampoos, body washes, hand sanitizers, and skincare products to help prevent the growth of bacteria, fungi, and other microorganisms.

Poly(hexamethylenebiguanide) is particularly useful in products intended for wound care and antiseptic purposes.
Poly(hexamethylenebiguanide) is used in medical and healthcare settings for wound care products, surgical scrubs, medical equipment disinfection, and contact lens solutions.
Its antimicrobial properties help reduce the risk of infections in healthcare environments.

Poly(hexamethylenebiguanide) can be incorporated into textiles and fabrics to impart antimicrobial properties.
Antimicrobial textiles find applications in medical textiles (such as hospital linens and surgical gowns), athletic wear, socks, and underwear to help control odor-causing bacteria and maintain freshness.
Poly(hexamethylenebiguanide) is used in swimming pool and spa water treatments as an alternative to chlorine.

Poly(hexamethylenebiguanide) helps control algae and bacteria growth in recreational water while being less harsh on the skin and eyes compared to chlorine.
Poly(hexamethylenebiguanide) may be found in household cleaning products, such as surface disinfectants and sanitizers, to help eliminate germs and bacteria on various surfaces around the home.
Poly(hexamethylenebiguanide) is used in industrial settings for microbial control in water systems, cooling towers, and manufacturing processes where microbial contamination can cause product spoilage or equipment damage.

Poly(hexamethylenebiguanide) may be used as a preservative to extend the shelf life of products and prevent microbial contamination.
Poly(hexamethylenebiguanide) is utilized in veterinary products such as wound care solutions, antiseptics, and shampoos for pets to prevent infections and promote healing.
Poly(hexamethylenebiguanide) can be used in agricultural settings as a biocide to control microbial growth in irrigation systems, crop protection formulations, and agricultural equipment sanitization.

Poly(hexamethylenebiguanide) may find application in the food industry for sanitizing food processing equipment, food contact surfaces, and food packaging materials to help maintain hygiene and prevent microbial contamination.
Poly(hexamethylenebiguanide) can be used in water purification systems, including potable water treatment and wastewater treatment, to control microbial populations and ensure water safety.
Poly(hexamethylenebiguanide) is sometimes incorporated into mouthwashes, toothpaste, and oral hygiene products for its antimicrobial properties, helping to reduce plaque formation, prevent gingivitis, and maintain oral health.

In horticulture, Poly(hexamethylenebiguanide) can be used in greenhouse applications to control fungal and bacterial diseases in plants and to disinfect gardening tools and equipment.
Poly(hexamethylenebiguanide)-treated fabrics are used in swimwear and other apparel to inhibit the growth of odor-causing bacteria and fungi, helping to keep garments fresh and hygienic, particularly in moist environments.
Poly(hexamethylenebiguanide) is found in pet care products such as pet shampoos, grooming sprays, and wound care solutions to help prevent infections and maintain pet hygiene.

Safety Profile Of Poly(hexamethylenebiguanide):
On the 20th of April 2018, the european commission decided to ban preservative uses of Poly(hexamethylenebiguanide) PT9 (Fibre, leather, rubber and polymerised materials preservatives).
Poly(hexamethylenebiguanide)’s still allowed for uses as disinfectants PT2 (Disinfectants and algaecides not intended for direct application to humans or animals).
In 2011, Poly(hexamethylenebiguanide) was classified as category 2 carcinogen by the European Chemical Agency, but it is still allowed in cosmetics in small quantities if exposure by inhalation is impossible.