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POLYETHYLENE GLYCOL 10000

CAS NUMBER: 25322-68-3

EC NUMBER: 500-038-2

MOLECULAR FORMULA: CH2OHCH2OH

MOLECULAR WEIGHT: 62.07

IUPAC NAME: ethane-1,2-diol

Polyethylene Glycol 10000 is used to modify therapeutic proteins and peptides to increase their solubility.
In gas chromatography, Polyethylene Glycol 10000 is used as a polar stationary phase.

Polyethylene Glycol 10000 is also useful in preserving objects obtained from the ocean.
As a dispersant, Polyethylene Glycol 10000 is used in toothpastes.
Polyethylene Glycol 10000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.

Polyethylene Glycol 10000 is a polymer of ethylene oxide.
This specific compound has a molecular weight average of 10,000.

Polyethylene Glycol 10000 is a compound used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene Glycol 10000 is often used as a polar stationary phase for Gas Chromatorgraphy.

Polyethylene Glycol 10000 commonly also used in mass spec experiments.
Polyethylene Glycol 10000 is also used to preserve objects that have been retrieved from the ocean.

Polyethylene Glycol 10000 is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels.
Polyethylene Glycol 10000 is made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions

Application:
Polyethylene Glycol 10000 can be used as a surfactant in the synthesis of Ni12P5 hollow microspheres via the hydrothermal method in the presence of hexamethylenetetramine (HMT).
Polyethylene Glycol 10000 significantly improves the formation of high-quality hollow microspheres, without this surfactant morphology is near-spherical particles.

Polyethylene Glycol 10000 can also be used as:
-A reactant to synthesize N-PEGylated-thiazolium salt, which is used as an organocatalyst for the benzoin condensation.
-A nonionic dispersive agent in the preparation Nd2Si2O7 ceramic pigment by a co-precipitation method.

Polyethylene Glycol 10000 is specified according to the requirements of the main international ICH guidelines and monographs
Polyethylene Glycol 10000 is condensation polymers of ethylene oxide and water with the general formula H(OCH2CH2)nOH.

Polyethylene Glycol 10000 is the most commercially important type of polyether.
Polyethylene Glycol 10000 is one of up to 700 low molecular weight compounds

Polyethylene Glycol 10000 has a freezing point of -10˚C
Polyethylene Glycol 10000 is colorless

Polyethylene Glycol 10000 is odorless viscous liquid
Wax-like solid with a melting point of up to 67˚C

Polyethylene Glycol 10000 finds use in different applications
Polyethylene Glycol 10000 has different physical properties (e.g. viscosity) due to chain length effects

Polyethylene Glycol 10000 has almost the same chemical properties as other PEG molecules.
The numbers frequently appearing in the names of Polyethylene Glycol 10000 indicate their average molecular weight.

A Polyethylene Glycol 10000 with n=9 has an average molecular weight of about 400 and is labeled PEG 400.
Polyethylene Glycol 10000 has a molecular weight distribution

So Polyethylene Glycol 10000 is polydisperse
Polyethylene Glycol 10000 is soluble in water and most organic solvents.

Polyethylene Glycol 10000 is non-toxic
Polyethylene Glycol 10000 is neutral and lubricating

Polyethylene Glycol 10000 is non-volatile
Polyethylene Glycol 10000 is non-irritating

Polyethylene Glycol 10000 is used as a solvent in various pharmaceuticals and drugs.
Polyethylene Glycol 10000 acts as dispersant in industry

Polyethylene Glycol 10000 is involved in the production of ointment and suppository bases
Polyethylene Glycol 10000 is used as vehicle and tablet excipient.

GENERAL PROPERTIES:

-Quality Level: 200

-Vapor Pressure: <0.01 hPa (20 °C)

-Form: Liquid

-Autoignition Temperature: 340 °C

-Potency: 28000 mg/kg LD50

-pH: 5-7 (20 °C, 100 g/L in H2O)

-Kinematic Viscosity: 500-900 cSt(20 °C)

-Melting Point: 58-63 °C

-Flash Point: 265 °C

-Density: 1.2 g/cm3 at 20 °C

-Bulk Density: 400‑500 kg/m3

-Storage Temperature: no temp limit

Polyethylene Glycol 10000 is a compound with wide compatibility over wide ranges of viscosity and hygroscopicity.
Polyethylene Glycol 10000 also exhibits excellent lubricity and low volatility.

Polyethylene Glycol 10000 is odorless and colorless.
Polyethylene Glycol 10000 has a hygroscopic property.

Polyethylene Glycol 10000 is readily soluble in water and most organic solvents except aliphatic hydrocarbons.
In addition, Polyethylene Glycol 10000 has excellent compatibility with various other chemicals.

APPLICATIONS:
Agriculture:
-Pesticide Vehicle

Ceramic and glass:
-Binder for glazes
-Screen print viscosity control

Chemical manufacture:
-Intermediate for copolymer
-PEG ester surfactant
-Complexing agent
-Methacrylate resin component

Cosmetic and Personal care:
-Antiseptic dental cream
-Deodorant sticks and roll-ons
-Hair dressing Preparation
-Shaving Cream
-Soaps

Pharmaceuticals:
-Capsule and pill binder
-Ointment bases
-Liquid preparation

Textile Treatment:
-Antistatic agent
-Finishing aids
-Sizing agents
-Spinning lubricant component

Rubber processing aid:
-Mould release agents
-Heat transfer agents-latex

Metals working:
-Electro Polishing
-Lubricants
-Brazing and soldering fluxes
-Lost wax casting

Polyethylene Glycol 10000 is widely used in a variety of pharmaceutical formulations, including parenteral, topical, ophthalmic, oral and rectal preparations.
Polyethylene Glycol 10000 does not irritate the skin

Polyethylene Glycol 10000 are stable, hydrophilic substances.
Polyethylene Glycol 10000 is water soluble

Thus, Polyethylene Glycol 10000 is easily removed from the skin by washing.
Therefore, Polyethylene Glycol 10000 are useful as ointment bases.

Solid types are often used in topical ointments, and the consistency of the base is adjusted by adding liquid grades of Polyethylene Glycol 10000.
Polyethylene Glycol 10000 can be used to adjust viscosity and consistency during the production phase of some products.

When used with other emulsifiers, Polyethylene Glycol 10000 can act as emulsion stabilizers.
Liquid Polyethylene Glycol 10000 is used as water-miscible solvents for the contents of soft gelatin capsules.

Polyethylene Glycol 10000 can increase the effectiveness of tablet binders and impart plasticity to granules.
Polyethylene Glycol 10000 can be used to improve the aqueous solubility or dissolution properties of poorly soluble compounds by making solid dispersions with a suitable polyethylene glycol.

Polyethylene Glycol 10000 was used as a solvent for steroids in osmotic pumps.
Polyethylene Glycol 10000 can be useful as hydrophilic polishing materials.

Polyethylene Glycol 10000 is widely used as plasticizers.
Polyethylene Glycol 10000 has been used in the preparation of urethane hydrogels used as a controlled release agent.

Polyethylene Glycol 10000 is a safe solvent and carrier for cosmetic use.
Polyethylene Glycol 10000 can act as a solvent in many substances.
Polyethylene Glycol 10000 is also a safe carrier.

PHYSICAL PROPERTIES:

-Molecular Weight: 62.07

-XLogP3: -1.4

-Hydrogen Bond Donor Count: 2

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 1

-Exact Mass: 62.036779430

-Monoisotopic Mass: 62.036779430

-Topological Polar Surface Area: 40.5 Å²

-Physical Description: Clear, colorless, syrupy, odorless liquid

-Color: Clear, colorless

-Solubility: 550 g/l

-Surface Tension: 47.99 mN/m

-pH Value: 4 - 7 (100 g/l, H₂O, 20 °C)

-Vapor Pressure: <0.1 hPa (20 °C)

-Form: Liquid

-Odor: Odorless

-Taste: Bittersweet taste

-Boiling Point: 197.3 °C

-Flash Point: 138.6 °C

Polyethylene Glycol 10000 is used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene Glycol 10000 is used as a polar stationary phase.

Polyethylene Glycol 10000 is also useful in preserving objects obtained from the ocean.
Polyethylene Glycol 10000 is a polymer of ethylene oxide.

Polyethylene Glycol 10000 commonly also used in mass spec experiments.
Polyethylene Glycol 10000 is also used to preserve objects that have been retrieved from the ocean.

CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 2

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 1

-Heavy Atom Count: 4

-Formal Charge: 0

-Complexity: 6

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Other Classes -> Ethylene Glycols

Polyethylene Glycol 10000 is colorless
Polyethylene Glycol 10000 is soluble in water and most organic solvents.

Polyethylene Glycol 10000 is used as a solvent in various pharmaceuticals and drugs.
Polyethylene Glycol 10000 is used as vehicle and tablet excipient.

Polyethylene Glycol 10000 is a compound with wide compatibility over wide ranges of viscosity and hygroscopicity.
Polyethylene Glycol 10000 has a hygroscopic property.

Polyethylene Glycol 10000 is water soluble
Polyethylene Glycol 10000 can be used to improve the aqueous solubility or dissolution properties of poorly soluble compounds by making solid dispersions with a suitable polyethylene glycol.

Polyethylene Glycol 10000 can be useful as hydrophilic polishing materials.
Polyethylene Glycol 10000 is widely used as plasticizers.
Polyethylene Glycol 10000 is also a safe carrier.

SYNONYM:

Polyethylene Glycol 10000
ethanediol
Zerex
Poly(ethylene glycol)
Lutrol-9
Polyethylene glycol 10000
ethyleneglycol
Aethylenglykol
Ethylenglycol
1,2-Ethandiol
Polyethylene glycol 1000
1,2-ethylene glycol
1,2-dihydroxy ethane
1, 2-Ethanediol
Polyethylene oxide
Carbowax 20
CAS-107-21-1
Polyethylene Glycols
Carbowax 1000
Carbowax 10000
Dowtherm 1000
Ethylene glycol polymer
PEG 3350
EINECS 203-473-3
Ethylene glycol homopolymer
Polyethylene Glycol 6000
1,2-Ethanediol homopolymer
ethyleneglycole
Athylenglykol
ehtylene glycol
etylene glycol
Dihydrocarveol, (-)-, mixture of isomers
1,2-Ethane-1,1,2,2-d4-diol-d2(9ci)
polyethylene glycol
Macrogol
Fridex
Tescol
Ethylene dihydrate
Norkool
Macrogol 400 BPC
Dowtherm SR 1
AI3-03050
2-ethanediol
Polyaethylenglykol
Ilexan E
4-vinyl cathecol
Polyaethylenglykole
MEG 100
Solbanon (TN)
1,2-ethane diol
1,2-ethane-diol
ethane-1.2-diol
Polyethylene Glycol 3000
ETHYLENE GLYCOL
Ethane-1,2-diol
1,2-ethanediol
107-21-1
glycol
monoethylene glycol
1,2-Dihydroxyethane
2-hydroxyethanol
Glycol alcohol
Ethylene alcohol
1,2-ethyleneglycol
ethan-1,2-diol
mono-ethylene glycol
Macrogol 10000
Carbowax 1540
1,2-ethylene-glycol
Ethylene glycol-[d6]
alpha-Hydro-omega-hydroxypoly(oxyethylene)
polyethylene glycol-400
Macrogol 400 (TN)
Macrogol 1500 (TN)
Glycol, polyethylene(300)
Macrogol 400 (JP17)
Polyethylene Glycol 300 NF
alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
Polyethylene glycol, diglycidyl bisphenol A polymer
Macrogol 6000 (JP17)
Poly(ethylene glycol) methyl ether
PEG 3600
PEG-10000
poly (ethylene glycol) methyl ether
Ethane-1,2-diol (Ethylene Glycol)
Polyethylene Glycol 3000, NF FCC
alpha,omega-hydroxypoly(ethylene oxide)