Quick Search
Polyethylene glycol 10000 is commonly also used in mass spec experiments.
Polyethylene glycol 10000 is also used to preserve objects that have been retrieved from the ocean.
Polyethylene glycol 10000 is used as excipients for pill and tablet binding or coating, gelatin capsules, ointments and creams, liquid medications, and suppositories.
CAS Number: 25322-68-3
EC (EINECS) Number: 500-038-2
Chemical Class: Polyether polymer (polyethylene glycol family)
Molecular Formula: H(OCH₂CH₂)nOH
Average Molecular Weight: 9000–11000 g/mol
SYNONYMS:
Polyethylene glycol, PEG, Polyethylene glycol 10000, Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 10000, PEG, Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 10000
Polyethylene glycol 10000 is a polyether compound with many applications from industrial manufacturing to medicine.
Polyethylene glycol 10000 is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels.
PEGs are made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions (polydispersity).
Polyethylene glycol 10000 is a polymer of ethylene oxide.
This specific compound, Polyethylene glycol 10000, has a MW average of 10,000.
Polyethylene glycol 10000 (PEG 10000, CAS 25322-68-3) is a high-molecular-weight (approx.), water-soluble, non-toxic polymer, typically found as white, flakes or powder.
Polyethylene Glycol 10000 (PEG 10000) is a high-molecular-weight synthetic polyether polymer belonging to the polyethylene glycol (PEG) family.
Polyethylene glycol 10000 is produced through the polymerization of ethylene oxide and contains repeating ethylene oxide units terminated by hydroxyl groups.
The number 10000 refers to the average molecular weight (~9000–11000 g/mol) of the polymer chain.
Polyethylene glycol 10000 is a hydrophilic, non-ionic compound widely used in pharmaceutical, cosmetic, biotechnology, and industrial formulations because of its excellent water solubility, chemical stability, lubricating properties, and low toxicity.
Polyethylene glycol 10000 typically appears as white flakes or powder and forms clear solutions in water.
Safety: Polyethylene glycol 10000 is generally considered non-toxic and non-irritant, though high, concentrated, or topically applied doses might cause mild reactions.
USES and APPLICATIONS of POLYETHYLENE GLYCOL 10000:
Polyethylene glycol 10000 is a compound used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene glycol 10000 is often used as a polar stationary phase for Gas Chromatorgraphy.
Polyethylene glycol 10000 is commonly also used in mass spec experiments.
Polyethylene glycol 10000 is also used to preserve objects that have been retrieved from the ocean.
Polyethylene glycol 10000 is used as excipients for pill and tablet binding or coating, gelatin capsules, ointments and creams, liquid medications, and suppositories.
Polyethylene glycol 10000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.
Polyethylene glycol 10000 can be used as a solubilizer.
Polyethylene glycol 10000 is a kind of biological materials or organic compounds that are widely used in life science research.
Polyethylene glycol 10000 is a viscosifier and moisturizer in hair conditioner and hair styling products.
Polyethylene glycol 10000 is also recommended as a binder in bath salts & denture cleaners when they are pressed into tablet form.
Industrial Applications of Polyethylene glycol 10000: Chemical / Cosmetics / Detergent / Food / Paint & Resin / Pharmaceutical / Rubber / Textile / Tile & Ceramic.
Polyethylene glycol 10000 is a compound used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene glycol 10000 can be used as a surfactant in the synthesis of Ni12P5 hollow microspheres via the hydrothermal method in the presence of hexamethylenetetramine (HMT).
Polyethylene glycol 10000 significantly improves the formation of high-quality hollow microspheres, without this surfactant morphology is near-spherical particles.
Polyethylene glycol 10000 can also be used as a reactant to synthesize N-PEGylated-thiazolium salt, which is used as an organocatalyst for the benzoin condensation.
Polyethylene glycol 10000 is used as a nonionic dispersive agent in the preparation Nd2Si2O7 ceramic pigment by a co-precipitation method.
Polyethylene glycol 10000 is used to modify therapeutic proteins and peptides to increase their solubility.
In gas chromatography, Polyethylene glycol 10000 is used as a polar stationary phase.
Polyethylene glycol 10000 is also useful in preserving objects obtained from the ocean.
As a dispersant, Polyethylene glycol 10000 is used in toothpastes.
Polyethylene glycol 10000 is used to modify therapeutic proteins and peptides to increase their solubility.
In gas chromatography, Polyethylene glycol 10000 is used as a polar stationary phase.
Polyethylene glycol 10000 is also useful in preserving objects obtained from the ocean.
As a dispersant, Polyethylene glycol 10000 is used in toothpastes.
Polyethylene glycol 10000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.
Polyethylene glycol 10000 is used as a binder, lubricant, and thickener in pharmaceuticals, cosmetics, and industrial applications.
Key Details and Applications: Polyethylene glycol 10000 is highly soluble in water and polar solvents.
Pharmaceuticals: Polyethylene glycol 10000 is used as a binder for tablets, in ointment bases, and for bowel cleansing solutions.
Industrial/Cosmetics: Polyethylene glycol 10000 is employed in detergents, as a dispersing agent in toothpaste, in deodorant sticks, and as a component in soaps.
Research: Polyethylene glycol 10000 is utilized in biotechnology for protein crystallization, DNA purification, and as a stationary phase in gas chromatography.
Applications of Polyethylene glycol 10000: Crystallization grade Polyethylene glycol 10,000 for formulating screens or for optimization
-Pharmaceutical Applications of Polyethylene glycol 10000:
Excipient in tablets and capsules as binder or lubricant
Suppository base material
Stabilizer in pharmaceutical suspensions and emulsions
Polyethylene glycol 10000 is used in PEGylation of therapeutic proteins and peptides to increase solubility and stability
Component in controlled-release drug delivery systems.
-Biotechnology and Laboratory Applications of Polyethylene glycol 10000:
Precipitation and purification of proteins, enzymes, and nucleic acids
Stabilizer in biological formulations
Polyethylene glycol 10000 is used in biomaterials and hydrogel preparation
Surface modification in biomedical research.
-Cosmetic and Personal Care Applications of Polyethylene glycol 10000:
Moisturizer and humectant in skin-care products
Binder in bath salts and denture-cleaning tablets
Thickening and viscosity-control agent in cosmetic formulations
Stabilizer in emulsions and dispersions.
-Industrial Applications of Polyethylene glycol 10000:
Raw material for surfactant synthesis
Lubricant and processing aid in polymer manufacturing
Dispersant in paints, inks, coatings, and pigments
Additive in adhesives and sealants
Processing aid in ceramics, rubber, textile, and detergent industries
Wetting agent and rheology modifier in industrial formulations.
BENEFITS AND ADVANTAGES of POLYETHYLENE GLYCOL 10000:
High water solubility and dispersibility
Low toxicity and good biocompatibility
Polyethylene glycol 10000 enhances lubrication and processability in formulations
Polyethylene glycol 10000 improves stability of suspensions and emulsions
Polyethylene glycol 10000 provides moisture retention and humectant properties
Polyethylene glycol 10000 increases solubility and stability of active ingredients
Compatible with many polymers and chemical ingredients
Stable polymer with long shelf life under appropriate storage conditions.
GENERAL PROPERTIES of POLYETHYLENE GLYCOL 10000:
*Non-ionic polymer
*Hydrophilic polyether backbone
*High molecular weight and viscosity
*Low volatility
*Capable of forming hydrogen bonds with water
*Chemically stable and relatively inert
*Compatible with many pharmaceutical excipients and industrial chemicals
*Polyethylene glycol 10000 forms clear aqueous solutions.
CHARACTERISTICS of POLYETHYLENE GLYCOL 10000:
Excellent moisture-retention ability (humectant)
Good film-forming properties
Effective binder and plasticizer
Polyethylene glycol 10000 provides lubrication and viscosity modification
Polyethylene glycol 10000 enhances dispersion of pigments and solid particles
Polyethylene glycol 10000 improves solubility of poorly soluble compounds
Polyethylene glycol 10000 provides steric stabilization in emulsions and suspensions
Compatible with ionic and non-ionic ingredients.
PHYSICAL and CHEMICAL PROPERTIES of POLYETHYLENE GLYCOL 10000:
Chemical Name: Polyethylene Glycol 10000 (PEG 10000)
Linear Formula: H(OCH₂CH₂)nOH
CAS Number: 25322‑68‑3
EC (EINECS) Number: 500‑038‑2
Average Molecular Weight: 9,000–11,250 g/mol (typical ~10,000 g/mol)
Molecular Formula (Representative): HOCH₂CH₂(OCH₂CH₂)nOH
Chemical Class: Polyether polymer / polyethylene glycol derivative
Appearance: White powder, flakes, or waxy solid
Odor: Odorless
Physical State: Solid at room temperature
Melting Point: 58–63 °C
Boiling Point: Decomposes before boiling (>200 °C)
Flash Point: 265–270 °C
Autoignition Temperature: ~340 °C
Density: ~1.2 g/cm³ at 20 °C
Bulk Density: 400–500 kg/m³
Vapor Pressure: <0.01 hPa at 20 °C
Refractive Index: ~1.46
Viscosity (kinematic, 20 °C): 500–900 cSt
pH (100 g/L aqueous solution): 5–7
Hydroxyl Value: ~10–12 mg KOH/g
Moisture Content: ≤1%
Solubility:
Highly soluble in water
Soluble in alcohols and certain aromatic solvents
Limited solubility in aliphatic hydrocarbons
Chemical Stability: Stable under normal storage conditions; chemically inert
WGK: 1 (slightly hazardous to water)
Storage Conditions: Store in a cool, dry, and dark place; avoid high temperatures
Chemical Name: Polyethylene Glycol 10000 (PEG 10000)
Linear Formula: H(OCH₂CH₂)nOH
CAS Number: 25322‑68‑3
NACRES: NA.23
PubChem Substance ID: 24887732
UNSPSC Code: 12352104
MDL Number: MFCD00081839
Average Molecular Weight: 9,000–11,000 g/mol
Hydroxyl Value: 10.0–12.5 mg KOH/g
Chemical Stability: Stable under normal conditions; incompatible with strong oxidizing agents
Appearance: White flakes, powder, or crystals
Odor: Not reported
Physical State: Solid at room temperature
Melting Point: 62–65 °C
Boiling Point: Not available (decomposes before boiling)
Flash Point: >113 °C (closed cup)
Autoignition Temperature: 305 °C
Decomposition Temperature: Not available
pH (5% aqueous solution): 5.0–7.5
pH (50 g/L aqueous solution, 25 °C): 5.5–7.0
Density: 1.210 g/cm³
Vapor Pressure: <0.01 hPa at 20 °C
Solubility: Highly soluble in water; clear and colorless 10% aqueous solution
Viscosity: Not reported
Partition Coefficient (n-octanol/water): Not available
Explosive Properties: None reported
Oxidizing Properties: None reported
Particle Characteristics: Not reported
Chemical Name: Polyethylene Glycol 10000 (PEG 10000)
Linear Formula: H(OCH₂CH₂)nOH
CAS Number: 25322‑68‑3
EC Number: 500‑038‑2
MDL Number: MFCD00081839
Quality Level: M‑Clarity™ MQ200
Average Molecular Weight: 9,000–10,000 g/mol
Hydroxyl Value: 10–12 mg KOH/g
Molecular Formula: (C₂H₄O)n
Appearance: White to pale yellow flakes or powder
Physical State: Solid at room temperature
Odor: Odorless or very faint
Solution Appearance: Clear aqueous solution, APHA ≤30
Melting Point: 58–63 °C
Boiling Point: Decomposes >200 °C
Flash Point: 265 °C
Autoignition Temperature: 340 °C
Ignition Point: 340 °C
Density: 1.2 g/cm³ at 20 °C
Bulk Density: 400–500 kg/m³
Vapor Pressure: <0.01 hPa at 20 °C
pH (100 g/L aqueous solution, 20 °C): 5–7.5
Viscosity (50% aqueous solution, 20 °C): 550–750 mPa·s (kinematic 500–900 cSt)
Water Solubility: ~500 g/L at 20 °C
Storage Temperature: Ambient, cool, dark place recommended
Moisture Content: ≤1%
Chemically stable under normal storage; incompatible with strong oxidizing agents
Refractive Index: Not specified
Transition Temperature: Not specified
Hygroscopicity: Slightly hygroscopic
SMILES: [H]OCCO
InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI Key: LYCAIKOWRPUZTN-UHFFFAOYSA-N
Chemical Name: Polyethylene Glycol 10000 (PEG 10000)
Linear Formula: H(OCH₂CH₂)nOH
CAS Number: 25322‑68‑3
EC Number: 500‑038‑2
MDL Number: MFCD00081839
NACRES: NA.22
UNSPSC Code: 13111021
Average Molecular Weight: 9,000–11,000 g/mol
Hydroxyl Value: 10–12 mg KOH/g
Appearance: White or colorless powder, flakes, or crystals
Physical State: Solid at room temperature
Odor: Odorless
Solution Appearance: Clear 5% aqueous solution at 25 °C
Refractive Index (n20/D): 1.465
Bulk Density: 400–500 kg/m³
Melting / Freezing Point: 58–63 °C (freezing point < −14.08 °C at 973.5 hPa)
Boiling Point: ~205.7 °C at 977.6 hPa (OECD Test Guideline 103); decomposes >200 °C
Flash Point: 138.6 °C (closed cup)
Autoignition Temperature: 360 °C
Density: 1.116 g/cm³ at 20 °C (975.5 hPa, OECD Test Guideline 109)
Vapor Pressure: <0.1 hPa at 20 °C
pH (5% aqueous solution): 4.5–7.5
Viscosity (25 °C): High; 800–1150 cSt at 98.9 °C
Water Solubility: Freely soluble (~256 g/L at 25 °C, OECD Test Guideline 105)
Partition Coefficient (log Pow, n-octanol/water): −0.698 at 30 °C (bioaccumulation not expected)
Chemical Stability: Stable under normal conditions; compatible with most organic and inorganic compounds; incompatible with strong oxidizing agents
Toxicity: Low toxicity; non-hazardous
Eco-Friendly Status: Biodegradable
Transport Information: Not regulated
Quality Standard: Meets AR/ACS specifications
Hygroscopicity: Slightly hygroscopic
FIRST AID MEASURES of POLYETHYLENE GLYCOL 10000:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of POLYETHYLENE GLYCOL 10000:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of POLYETHYLENE GLYCOL 10000:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYETHYLENE GLYCOL 10000:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of POLYETHYLENE GLYCOL 10000:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of POLYETHYLENE GLYCOL 10000:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
