PRODUCTS

POLYETHYLENE GLYCOL 3000

CAS NUMBER: 25322-68-3

EC NUMBER: 500-038-2

MOLECULAR FORMULA: CH2OHCH2OH

MOLECULAR WEIGHT: 62.07

IUPAC NAME: ethane-1,2-diol

Polyethylene Glycol 3000 is used as an inactive ingredient in the pharmaceutical industry as a solvent
Polyethylene Glycol 3000 is used as a plasticizer

Polyethylene Glycol 3000 also can be used in surfactants
Polyethylene Glycol 3000 is used in ointment manufacturing

Polyethylene Glycol 3000 found in suppository base, and tablet and capsule lubricant.
Polyethylene Glycol 3000 is a cationic surfactant that has antibiotic-resistant properties.

Polyethylene Glycol 3000 can be used to treat cancers and bacterial infections.
Polyethylene Glycol 3000 is a superparamagnetic iron particles that can be used to target specific cells because of its magnetic properties.
Polyethylene Glycol 3000 is also an acylation reaction with an amine group and an ester bond.

Polyethylene Glycol 3000 can be used as:
-A surface-modification agent in the synthesis of monodispersed magnetite colloidal magnetic nanoparticles.
-A precipitating agent in the crystallization of oligoxyloglucan reducing-end specific cellobiohydrolase (OXG-RCBH) by the hanging-drop vapor diffusion method.
-A solvent and phase-transfer catalyst (PTC) in the application of aqueous biphasic reactive extraction.
-An additive in the preparation of polysulfone membrane to study the porometry.

Polyethylene Glycol 3000 is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.
Polyethylene Glycol 3000 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.
The structure of Polyethylene Glycol 3000 is commonly expressed as H−(O−CH2−CH2)n−OH.

MEDICAL USES OF POLYETHYLENE GLYCOL 3000:
Pharmaceutical-grade Polyethylene Glycol 3000 is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
Polyethylene Glycol 3000 is the basis of a number of laxatives
Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy.
Polyethylene Glycol 3000 is used in medicines for treating disimpaction and maintenance therapy for children with constipation.
When attached to various protein medications or drug carriers, polyethylene glycol of suitable length slows down their clearance from the blood.

CHEMICAL USES OF POLYETHYLENE GLYCOL 3000:
Because Polyethylene Glycol 3000 is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.
Polyethylene Glycol 3000 has a low toxicity and is used in a variety of products.

The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.
Since Polyethylene Glycol 3000 is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres).

Polyethylene Glycol 3000 also is unlikely to have specific interactions with biological chemicals.
These properties make Polyethylene Glycol 3000 one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique.

Polyethylene Glycol 3000 is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
Polyethylene Glycol 3000 is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases.

Polyethylene Glycol 3000 replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, Polyethylene Glycol 3000 is used when working with green wood as a stabilizer, and to prevent shrinkage.
Polyethylene Glycol 3000 has been used to preserve the painted colors

Polyethylene Glycol 3000 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
Polyethylene Glycol 3000 derivatives, such as narrow range ethoxylates, are used as surfactants.
Polyethylene Glycol 3000 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes

BIOLOGICAL USES OF POLYETHYLENE GLYCOL 3000:
Polyethylene Glycol 3000 can be modified and crosslinked into a hydrogel and used to mimic the extracellular matrix (ECM) environment for cell encapsulation and studies.
An example study was done using PEG-diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages.
This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.

Polyethylene Glycol 3000 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
Polyethylene Glycol 3000 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.

COMMERICAL USES OF POLYETHYLENE GLYCOL 3000:
Polyethylene Glycol 3000 is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin).
Polyethylene Glycol 3000 is used in a number of toothpastes as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
Polyethylene Glycol 3000 is also under investigation for use in body armor, and in tattoos to monitor diabetes
In low-molecular-weight formulations (e.g. PEG 400), Polyethylene Glycol 3000 is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads.
Polyethylene Glycol 3000 is also used as an anti-foaming agent in food and drinks – its INS number is 1521 or E1521 in the EU

INDUSTRIAL USES OF POLYETHYLENE GLYCOL 3000:
Dimethyl ethers of Polyethylene Glycol 3000 are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the syngas stream.

Polyethylene Glycol 3000 has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
Polyethylene Glycol 3000 is also used as a polymer host for solid polymer electrolytes.

Polyethylene Glycol 3000 is injected into industrial processes to reduce foaming in separation equipment.
Polyethylene Glycol 3000 is used as a binder in the preparation of technical ceramics.
Polyethylene Glycol 3000 is used as an additive to silver halide photographic emulsions.

ENTERTAINMENT USES OF POLYETHYLENE GLYCOL 3000:
Polyethylene Glycol 3000 is used to extend the size and durability of very large soap bubbles.
Polyethylene Glycol 3000 is the main ingredient in many personal lubricants. (Not to be confused with propylene glycol.)

Polyethylene Glycol 3000 is the main ingredient in the paint (known as "fill") in paintballs.
Polyethylene Glycol 3000 is a clear, colorless syrupy liquid.

Polyethylene Glycol 3000 is a synthetic liquid substance that absorbs water.
Polyethylene Glycol 3000 is odorless, but has a sweet taste.

Polyethylene Glycol 3000 is used to make antifreeze and de-icing solutions for cars, airplanes, and boats.
Polyethylene Glycol 3000 is also used in hydraulic brake fluids and inks used in stamp pads, ballpoint pens, and print shops.

PHYSICAL PROPERTIES:

-Molecular Weight: 62.07

-XLogP3: -1.4

-Hydrogen Bond Donor Count: 2

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 1

-Exact Mass: 62.036779430

-Monoisotopic Mass: 62.036779430

-Topological Polar Surface Area: 40.5 Å²

-Physical Description: Clear, colorless, syrupy, odorless liquid

-Color: Clear, colorless

-Form: Liquid

-Odor: Odorless

-Taste: Bittersweet taste

-Boiling Point: 197.3 °C

-Density: 1.21 g/cm3 (20 °C)

-Flash Point: 138.6 °C

-Ignition Temperature: 420 °C

-Melting Point: 57.5 °C

-pH Value: 4 - 7 (100 g/l, H₂O, 20 °C)

-Vapor Pressure: <0.1 hPa (20 °C)

-Bulk Density: 400 - 500 kg/m3

-Solubility: 550 g/l

-Surface Tension: 47.99 mN/m

Polyethylene Glycol 3000 is a binder, coating agent and dispersing agent
Polyethylene Glycol 3000 is flavoring adjuvant, and plasticizing agent

Polyethylene Glycol 3000 is a clear, colorless
Polyethylene Glycol 3000 is viscous liquid

Polyethylene Glycol 3000 is hygroscopic liquid resembling paraffin (white, waxy, or flakes), with a ph of 4.0–7.5 in 1:20 concentration.
Polyethylene Glycol 3000 is soluble in water (mw 1,000) and many organic solvents.

CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 2

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 1

-Heavy Atom Count: 4

-Formal Charge: 0

-Complexity: 6

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Other Classes -> Ethylene Glycols

Polyethylene Glycol 3000 is used as a plasticizer
Polyethylene Glycol 3000 also can be used in surfactants
Polyethylene Glycol 3000 is used in ointment manufacturing

Polyethylene Glycol 3000 is a cationic surfactant that has antibiotic-resistant properties.
Polyethylene Glycol 3000 can be used to treat cancers and bacterial infections.

Polyethylene Glycol 3000 is a superparamagnetic iron particles that can be used to target specific cells because of its magnetic properties.
Polyethylene Glycol 3000 is also an acylation reaction with an amine group and an ester bond.

Polyethylene Glycol 3000 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
Polyethylene Glycol 3000 is used in a number of toothpastes as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.

Polyethylene Glycol 3000 is also under investigation for use in body armor, and in tattoos to monitor diabetes
Polyethylene Glycol 3000 is also used as a polymer host for solid polymer electrolytes.

Polyethylene Glycol 3000 is used as a binder in the preparation of technical ceramics.
Polyethylene Glycol 3000 is used as an additive to silver halide photographic emulsions.

Polyethylene Glycol 3000 is a clear, colorless syrupy liquid.
Polyethylene Glycol 3000 is a synthetic liquid substance that absorbs water.
Polyethylene Glycol 3000 is odorless, but has a sweet taste.

SYNONYMS:

Polyethylene Glycol 3000
ETHYLENE GLYCOL
Ethane-1,2-diol
1,2-ethanediol
107-21-1
glycol
monoethylene glycol
1,2-Dihydroxyethane
2-hydroxyethanol
Glycol alcohol
Ethylene alcohol
polyethylene glycol
Macrogol
Fridex
Tescol
Ethylene dihydrate
Norkool
Macrogol 400 BPC
Dowtherm SR 1
ethanediol
Zerex
Poly(ethylene glycol)
Lutrol-9
Polyethylene glycol 200
ethyleneglycol
Aethylenglykol
Ethylenglycol
1,2-Ethandiol
Polyethylene glycol 1000
1,2-ethylene glycol
1,2-dihydroxy ethane
1, 2-Ethanediol
Polyethylene oxide
Carbowax 20
CAS-107-21-1
Polyethylene Glycols
Carbowax 400
Carbowax 1000
Dowtherm 4000
Ethylene glycol polymer
PEG 3350
EINECS 203-473-3
Ethylene glycol homopolymer
Polyethylene Glycol 6000
1,2-Ethanediol homopolymer
ethyleneglycole
Athylenglykol
ehtylene glycol
etylene glycol
AI3-03050
2-ethanediol
Polyaethylenglykol
Ilexan E
4-vinyl cathecol
Polyaethylenglykole
MEG 100
Solbanon (TN)
1,2-ethane diol
1,2-ethane-diol
ethane-1.2-diol
GXT
PEG 4000
1,2-ethyleneglycol
ethan-1,2-diol
mono-ethylene glycol
Macrogol 400
Carbowax 1540
1,2-ethylene-glycol
Ethylene glycol-[d6]
alpha-Hydro-omega-hydroxypoly(oxyethylene)
polyethylene glycol-400
Macrogol 400 (TN)
Macrogol 1500 (TN)
Glycol, polyethylene(300)
Macrogol 400 (JP17)
ETHYLENE GLYCOL [II]
ETHYLENE GLYCOL [MI]
Polyethylene Glycol 300 NF
alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
Polyethylene glycol, diglycidyl bisphenol A polymer
Macrogol 6000 (JP17)
Poly(ethylene glycol) methyl ether
1,2-ETHANEDIOL (GLYCOL)
PEG 3600
PEG-1000
poly (ethylene glycol) methyl ether
Ethane-1,2-diol (Ethylene Glycol)
Polyethylene Glycol 3000, NF FCC
alpha,omega-hydroxypoly(ethylene oxide)
Oxirane, 2,2'-((1-methylethylidene)bis(4,1-phenyleneoxymethylene))bis-, polymer with alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
Dihydrocarveol, (-)-, mixture of isomers
1,2-Ethane-1,1,2,2-d4-diol-d2(9ci)
Ethylene glycol, spectrophotometric grade, >=99%
Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-
ethylene glycol;1,2-ethanediol;ethane-1,2-diol;glycolethylene glycol;ethanediol;ethylene glycol 1,2-ethanediol ethane-1,2-diol glycolethylene glycol ethanediol